Published in Nucleic Acids Res on July 01, 2002
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation. Blood (2008) 1.51
Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res (2009) 1.39
Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf. Mol Cell Biol (2004) 1.31
ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells. Proc Natl Acad Sci U S A (2014) 1.14
Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One (2012) 1.06
Transcriptional regulation of endothelial cell and vascular development. Circ Res (2013) 1.03
The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism. Mol Cell Biol (2004) 1.02
Etsrp/Etv2 is directly regulated by Foxc1a/b in the zebrafish angioblast. Circ Res (2011) 0.93
ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells. Oncol Rep (2012) 0.87
Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis. J Biol Chem (2012) 0.83
Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism. Mol Cancer (2011) 0.80
The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell Development. Mol Cells (2015) 0.79
ETS transcription factor ERG cooperates with histone demethylase KDM4A. Oncol Rep (2016) 0.78
A short amino acid sequence able to specify nuclear location. Cell (1984) 21.17
GAL4-VP16 is an unusually potent transcriptional activator. Nature (1988) 16.53
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell (1996) 11.02
Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell (1991) 9.96
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science (1994) 7.60
Negative effect of the transcriptional activator GAL4. Nature (1988) 7.15
Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell (1992) 7.07
Regulation of the specific DNA binding function of p53. Cell (1992) 6.16
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J (1996) 5.17
Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complex. Science (1991) 4.98
Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF. Nature (1992) 3.88
Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. EMBO J (1998) 3.86
Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator. Genes Dev (1995) 3.81
ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell (2000) 3.78
Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif. Genes Dev (1992) 3.69
Activation of ternary complex factor Elk-1 by MAP kinases. EMBO J (1993) 3.47
Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays (2000) 3.17
A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor. EMBO J (1992) 2.93
Ets target genes: past, present and future. Oncogene (2000) 2.58
Functionally related motor neuron pool and muscle sensory afferent subtypes defined by coordinate ETS gene expression. Cell (1998) 2.57
The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits. Biochem J (1993) 2.49
Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. Genes Dev (1992) 2.42
Spatial flexibility in ternary complexes between SRF and its accessory proteins. EMBO J (1992) 2.28
Specificity within the ets family of transcription factors. Adv Cancer Res (1998) 2.21
Structural studies of Ets-1/Pax5 complex formation on DNA. Mol Cell (2001) 2.16
Eukaryotic expression vectors for the analysis of mutant proteins. Nucleic Acids Res (1989) 2.15
The ETS-domain transcription factor family. Int J Biochem Cell Biol (1997) 1.94
Characterization of the cooperative function of inhibitory sequences in Ets-1. Mol Cell Biol (1996) 1.85
Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B. EMBO J (1997) 1.73
Definition of an Ets1 protein domain required for nuclear localization in cells and DNA-binding activity in vitro. Mol Cell Biol (1989) 1.67
SAP1a is a nuclear target of signaling cascades involving ERKs. Oncogene (1995) 1.65
Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers. EMBO J (1999) 1.56
The Ets family of proteins: weak modulators of gene expression in quest for transcriptional partners. Crit Rev Oncog (1994) 1.45
Functional dissection of the transcription factor Elk-1. Oncogene (1994) 1.42
An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes. Mol Cell Biol (1995) 1.40
Analysis of the ERK-stimulated ETS transcription factor ER81. Mol Cell Biol (1996) 1.36
Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein. Oncogene (1993) 1.32
HER2/Neu-mediated activation of the ETS transcription factor ER81 and its target gene MMP-1. Oncogene (2001) 1.30
Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice. Nature (1996) 1.25
Two independent activation domains in c-Ets-1 and c-Ets-2 located in non-conserved sequences of the ets gene family. Oncogene (1992) 1.25
DNA binding specificities of Spi-1/PU.1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter. Oncogene (1995) 1.23
The Ewing's sarcoma gene product functions as a transcriptional activator. Cancer Res (2001) 1.19
Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex. Oncogene (1996) 1.16
The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression. J Biol Chem (1997) 1.13
The PEA3 Ets transcription factor comprises multiple domains that regulate transactivation and DNA binding. J Biol Chem (2000) 1.12
Male sexual dysfunction in mice bearing targeted mutant alleles of the PEA3 ets gene. Mol Cell Biol (2000) 1.12
Molecular characterization of the zebrafish PEA3 ETS-domain transcription factor. Oncogene (1998) 1.11
DNA binding by the ETS-domain transcription factor PEA3 is regulated by intramolecular and intermolecular protein.protein interactions. J Biol Chem (2001) 1.10
Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors. Oncogene (1997) 1.06
Altered Ets transcription factor activity in prostate tumor cells inhibits anchorage-independent growth, survival, and invasiveness. Oncogene (2000) 1.04
Characterization of the DNA binding and transcriptional activation domains of the erg protein. Oncogene (1993) 0.98
Interactions of proteases and protease inhibitors in Sertoli-germ cell cocultures preceding the formation of specialized Sertoli-germ cell junctions in vitro. J Androl (1998) 0.94
Titration by estrogen receptor activation function-2 of targets that are downstream from coactivators. Mol Endocrinol (1999) 0.92
Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin. Oncogene (1997) 0.92
The analysis of the transcriptional activator PrnA reveals a tripartite nuclear localisation sequence. J Mol Biol (2000) 0.88
Ets-1 flips for new partner Pax-5. Structure (2002) 0.85
Regulation of tissue inhibitor of metalloproteinases-1 in rat Sertoli cells: induction by germ cell residual bodies, interleukin-1alpha, and second messengers. Biol Reprod (2000) 0.83
Transcriptional activity and constitutive nuclear localization of the ETS protein Elf-1. FEBS Lett (1997) 0.78
[Correlation between expression of metastasis-related genes and lymph node metastasis in testicular cancer]. Hinyokika Kiyo (2000) 0.78
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D. Biochem Biophys Res Commun (2007) 1.75
Diversity within the JMJD2 histone demethylase family. Biochem Biophys Res Commun (2006) 1.74
Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma. Hum Mol Genet (2007) 1.67
KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells. Cancer Res (2013) 1.65
ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors. Biochim Biophys Acta (2012) 1.58
TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses. Oncogene (2002) 1.53
Involvement of RNA helicases p68 and p72 in colon cancer. Cancer Res (2007) 1.41
Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res (2009) 1.39
Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor. Oncogene (2003) 1.38
Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential. Biochemistry (2010) 1.38
Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu. J Biol Chem (2004) 1.35
Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300. Oncogene (2003) 1.32
Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf. Mol Cell Biol (2004) 1.31
Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors. Bioorg Med Chem Lett (2009) 1.28
Vascular endothelial growth factor expression is up-regulated by EWS-ETS oncoproteins and Sp1 and may represent an independent predictor of survival in Ewing's sarcoma. Clin Cancer Res (2004) 1.28
Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu. Mol Cell Biol (2003) 1.27
Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue. J Biol Chem (2002) 1.25
Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene. J Cell Biochem (2002) 1.22
HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81. J Biol Chem (2003) 1.16
Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71. J Cell Biochem (2006) 1.15
Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. J Biol Chem (2002) 1.14
Repression of Smad3 activity by histone demethylase SMCX/JARID1C. Biochem Biophys Res Commun (2007) 1.06
Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One (2012) 1.06
The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells. J Cell Biochem (2012) 1.05
Rcl is a novel ETV1/ER81 target gene upregulated in breast tumors. J Cell Biochem (2008) 1.04
Regulation of Her2/neu promoter activity by the ETS transcription factor, ER81. J Cell Biochem (2002) 1.03
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1. Mol Cancer (2014) 0.99
Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase. J Biol Chem (2010) 0.99
Cloning of the murine ER71 gene (Etsrp71) and initial characterization of its promoter. Genomics (2005) 0.98
Oncogenic features of the JMJD2A histone demethylase in breast cancer. Int J Oncol (2012) 0.98
Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer. Gynecol Oncol (2005) 0.97
Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10. Biochem Biophys Res Commun (2010) 0.96
Upregulation of the matrix metalloproteinase-1 gene by the Ewing's sarcoma associated EWS-ER81 and EWS-Fli-1 oncoproteins, c-Jun and p300. FEBS Lett (2003) 0.93
Histone demethylase JMJD5 is essential for embryonic development. Biochem Biophys Res Commun (2012) 0.92
Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF. J Cell Biochem (2007) 0.92
Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells. Biochim Biophys Acta (2011) 0.90
Developmental localization of nephrin in zebrafish and medaka pronephric glomerulus. J Histochem Cytochem (2013) 0.88
ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells. Oncol Rep (2012) 0.87
Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism. PLoS One (2013) 0.85
14-3-3 proteins modulate the ETS transcription factor ETV1 in prostate cancer. Cancer Res (2013) 0.83
Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis. J Biol Chem (2012) 0.83
Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1. J Clin Invest (2016) 0.80