Published in Nat Rev Immunol on June 01, 2002
Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells. Immunology (2006) 2.03
At the bedside: CTLA-4- and PD-1-blocking antibodies in cancer immunotherapy. J Leukoc Biol (2013) 1.90
T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy. Blood (2008) 1.69
Metabolic control of the Treg/Th17 axis. Immunol Rev (2013) 1.26
Pathogenesis beyond the cancer clone(s) in multiple myeloma. Blood (2015) 1.04
Immunomodulatory therapy for melanoma: ipilimumab and beyond. Clin Dermatol (2013) 1.04
Azathioprine: old drug, new actions. J Clin Invest (2003) 0.98
Immune checkpoint blockade in cancer treatment: a double-edged sword cross-targeting the host as an "innocent bystander". Toxins (Basel) (2014) 0.92
T-cell costimulatory molecules in acute-graft-versus host disease: therapeutic implications. Bone Marrow Res (2010) 0.87
Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia. Respir Res (2005) 0.86
Role of diacylglycerol kinases in T cell development and function. Crit Rev Immunol (2013) 0.85
NKG2D expression by CD8+ T cells contributes to GVHD and GVT effects in a murine model of allogeneic HSCT. Blood (2015) 0.83
IL-2 regulates SEB induced toxic shock syndrome in BALB/c mice. PLoS One (2009) 0.83
Immunotherapy of Ovarian Cancer: The Role of Checkpoint Inhibitors. J Immunol Res (2015) 0.82
Comparative analysis of cytotoxic T lymphocyte response induced by dendritic cells loaded with hepatocellular carcinoma -derived RNA or cell lysate. Int J Biol Sci (2010) 0.82
Multiple sclerosis: experimental models and reality. Acta Neuropathol (2016) 0.82
Co-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells? Front Immunol (2015) 0.80
Immune checkpoint inhibitor combinations in solid tumors: opportunities and challenges. Immunotherapy (2016) 0.77
VSIG4 expression on macrophages facilitates lung cancer development. Lab Invest (2014) 0.77
Review of Mouse Models of Graves' Disease and Orbitopathy-Novel Treatment by Induction of Tolerance. Clin Rev Allergy Immunol (2017) 0.77
Positive and negative selection, self-nonself discrimination and the roles of costimulation and anergy. Sci Rep (2012) 0.76
Making many from few: IL-12p40 as a model for the combinatorial assembly of heterodimeric cytokines. Cytokine (2015) 0.76
Autoimmunity: Antigen-specific immunotherapy. Nature (2016) 0.76
Hepatitis B virus X protein modulates renal tubular epithelial cell-induced T-cell and macrophage responses. Immunol Cell Biol (2015) 0.75
Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri. J Immunol Res (2015) 0.75
Can plasma exchange therapy induce regulatory T lymphocytes in multiple sclerosis patients? Clin Exp Immunol (2012) 0.75
Interplay of polarity proteins and GTPases in T-lymphocyte function. Clin Dev Immunol (2012) 0.75
The Relationship Between Dormant Cancer Cells and Their Microenvironment. Adv Cancer Res (2016) 0.75
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nat Immunol (2006) 3.09
BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest (2003) 2.87
Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med (2004) 2.76
Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. Immunity (2007) 2.61
Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization. J Exp Med (2005) 2.51
Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses. J Immunol (2003) 2.17
Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat Immunol (2003) 2.11
Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data. Nat Protoc (2007) 2.04
Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells. J Clin Invest (2005) 1.92
B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells. J Exp Med (2003) 1.89
Activation-induced B cell fates are selected by intracellular stochastic competition. Science (2012) 1.84
The genetic network controlling plasma cell differentiation. Semin Immunol (2011) 1.66
A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells. J Immunol (2003) 1.53
Estimating lymphocyte division and death rates from CFSE data. Bull Math Biol (2006) 1.53
Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage. J Immunol (2005) 1.52
Division-linked differentiation can account for CD8+ T-cell phenotype in vivo. Eur J Immunol (2009) 1.51
Isotype switching by human B cells is division-associated and regulated by cytokines. J Immunol (2002) 1.36
Stochastic model of T cell proliferation: a calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival. J Immunol (2003) 1.35
Divide and conquer: the importance of cell division in regulating B-cell responses. Immunology (2004) 1.31
Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow. Blood (2003) 1.19
Differential requirement for OBF-1 during antibody-secreting cell differentiation. J Exp Med (2005) 1.10
Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty. Immunol Cell Biol (2003) 1.08
Stretched cell cycle model for proliferating lymphocytes. Proc Natl Acad Sci U S A (2014) 1.04
Intracellular competition for fates in the immune system. Trends Cell Biol (2012) 1.03
Quantitative regulation of B cell division destiny by signal strength. J Immunol (2008) 1.03
CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2. Eur J Immunol (2002) 1.02
High rate of antibody secretion is not integral to plasma cell differentiation as revealed by XBP-1 deficiency. J Immunol (2012) 1.00
Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses. J Immunol (2011) 0.99
TCR affinity promotes CD8+ T cell expansion by regulating survival. J Immunol (2007) 0.99
Determining the expected variability of immune responses using the cyton model. J Math Biol (2007) 0.99
Platelet senescence is regulated by an internal timer, not damage inflicted by hits. Blood (2010) 0.97
Modelling cell lifespan and proliferation: is likelihood to die or to divide independent of age? J R Soc Interface (2005) 0.96
Cross-linking surface Ig delays CD40 ligand- and IL-4-induced B cell Ig class switching and reveals evidence for independent regulation of B cell proliferation and differentiation. J Immunol (2002) 0.95
Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals. Nat Commun (2013) 0.94
Why does the thymus involute? A selection-based hypothesis. Trends Immunol (2009) 0.93
Automatic generation of lymphocyte heterogeneity: Division-dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4+ T cells are independently regulated. Immunol Cell Biol (2004) 0.93
Immunophenotypic changes induced on human HL60 leukaemia cells by 1alpha,25-dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol-13-acetate. Leuk Res (2005) 0.89
'Proliferative' and 'synthetic' airway smooth muscle cells are overlapping populations. Immunol Cell Biol (2004) 0.89
Decision criteria for resolving isotype switching conflicts by B cells. Eur J Immunol (2005) 0.88
Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models. Bull Math Biol (2009) 0.85
Modelling naive T-cell homeostasis: consequences of heritable cellular lifespan during ageing. Immunol Cell Biol (2009) 0.84
Targeting plasma cells in autoimmune diseases. J Exp Med (2004) 0.84
A minimum of two distinct heritable factors are required to explain correlation structures in proliferating lymphocytes. J R Soc Interface (2010) 0.83
The proliferative response of CD4 T cells to steady-state CD8+ dendritic cells is restricted by post-activation death. Int Immunol (2006) 0.83
High-affinity B cell receptor ligation by cognate antigen induces cytokine-independent isotype switching. J Immunol (2010) 0.82
A model for studying the hemostatic consumption or destruction of platelets. PLoS One (2013) 0.78
Shedding light on cell cycle control by T and B lymphocytes. Cell Cycle (2015) 0.76