Published in EMBO J on July 01, 2002
How the fanconi anemia pathway guards the genome. Annu Rev Genet (2009) 4.94
A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. Mol Cell Biol (2003) 3.85
Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol Cell Biol (2004) 3.20
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia. Nat Genet (2011) 2.72
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. EMBO J (2007) 2.00
Fanconi anemia FANCG protein in mitigating radiation- and enzyme-induced DNA double-strand breaks by homologous recombination in vertebrate cells. Mol Cell Biol (2003) 1.84
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol Cell Biol (2006) 1.65
Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM. EMBO J (2004) 1.56
Evidence for subcomplexes in the Fanconi anemia pathway. Blood (2006) 1.43
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination. Mol Cell Biol (2007) 1.40
Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif. J Biol Chem (2009) 1.22
The genetic and biochemical basis of FANCD2 monoubiquitination. Mol Cell (2014) 1.22
Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum. PLoS Genet (2009) 1.19
Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway. Oncogene (2008) 1.18
FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures. J Biol Chem (2009) 1.15
The Fanconi anemia pathway and ubiquitin. BMC Biochem (2007) 1.10
Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy. Curr Cancer Drug Targets (2009) 1.00
The Fanconi Anemia Pathway Protects Genome Integrity from R-loops. PLoS Genet (2015) 0.96
Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases. Nucleic Acids Res (2014) 0.96
A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. Nucleic Acids Res (2013) 0.92
Insights into Fanconi Anaemia from the structure of human FANCE. Nucleic Acids Res (2007) 0.89
The Fanconi anemia ID2 complex: dueling saxes at the crossroads. Cell Cycle (2014) 0.87
The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway. J Biol Chem (2014) 0.84
Towards a molecular understanding of the fanconi anemia core complex. Anemia (2012) 0.84
The Fanconi anemia pathway and DNA interstrand cross-link repair. Protein Cell (2011) 0.83
Specificity and disease in the ubiquitin system. Biochem Soc Trans (2016) 0.82
Fanconi anemia proteins and their interacting partners: a molecular puzzle. Anemia (2012) 0.82
The Fanconi anemia pathway in replication stress and DNA crosslink repair. Cell Mol Life Sci (2012) 0.81
The phenotype of FancB-mutant mouse embryonic stem cells. Mutat Res (2011) 0.81
The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2. Cell Rep (2016) 0.75
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Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell (2001) 8.99
Themes and variations on ubiquitylation. Nat Rev Mol Cell Biol (2001) 8.68
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Involvement of Brca2 in DNA repair. Mol Cell (1998) 4.41
In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature (2000) 4.38
The emerging genetic and molecular basis of Fanconi anaemia. Nat Rev Genet (2001) 4.07
Positional cloning of a novel Fanconi anemia gene, FANCD2. Mol Cell (2001) 2.33
Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1. Nat Med (2001) 2.26
Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens. Nature (1976) 2.24
Spontaneous functional correction of homozygous fanconi anaemia alleles reveals novel mechanistic basis for reverse mosaicism. Nat Genet (1999) 1.81
Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. Mol Cell Biol (1999) 1.73
Evidence for at least eight Fanconi anemia genes. Am J Hum Genet (1997) 1.61
Isolation of a cDNA representing the Fanconi anemia complementation group E gene. Am J Hum Genet (2000) 1.51
Fanconi anemia and DNA repair. Hum Mol Genet (2001) 1.50
The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG. Hum Mol Genet (2000) 1.48
The Fanconi anemia polypeptide FACC is localized to the cytoplasm. Proc Natl Acad Sci U S A (1994) 1.36
Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway. Hum Mol Genet (2001) 1.34
A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA. Proc Natl Acad Sci U S A (1999) 1.32
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation. Proc Natl Acad Sci U S A (1998) 1.30
Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. Cancer Res (1982) 1.24
Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase. Blood (1998) 1.24
The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors. Mol Cell Biol (2000) 1.23
FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity. EMBO J (2001) 1.22
The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex. Nat Genet (1997) 1.20
Localization of Fanconi anemia C protein to the cytoplasm of mammalian cells. Proc Natl Acad Sci U S A (1994) 1.17
The Fanconi anemia group C gene product is located in both the nucleus and cytoplasm of human cells. Blood (1998) 1.01
A Leu554-to-Pro substitution completely abolishes the functional complementing activity of the Fanconi anemia (FACC) protein. Hum Mol Genet (1993) 0.99
Biallelic inactivation of BRCA2 in Fanconi anemia. Science (2002) 9.31
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet (2006) 4.98
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nat Genet (2005) 4.92
A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet (2003) 4.79
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat Genet (2005) 4.57
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. Mol Cell (2007) 4.28
The emerging genetic and molecular basis of Fanconi anaemia. Nat Rev Genet (2001) 4.07
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med (2003) 4.04
A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. Mol Cell Biol (2003) 3.85
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet (2011) 3.74
Transcatheter valve-in-valve implantation for failed bioprosthetic heart valves. Circulation (2010) 3.65
The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair. Mol Cell (2004) 3.44
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet (2013) 3.42
Aurora-A: the maker and breaker of spindle poles. J Cell Sci (2007) 3.20
Extreme diving of beaked whales. J Exp Biol (2006) 2.95
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X-linked inheritance of Fanconi anemia complementation group B. Nat Genet (2004) 2.86
Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion. Nat Genet (2005) 2.77
A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol (2007) 2.73
Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway. Science (2010) 2.67
BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity. EMBO J (2005) 2.60
The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway. Nat Struct Mol Biol (2005) 2.55
Lung cancer screening with sputum cytologic examination, chest radiography, and computed tomography: an update for the U.S. Preventive Services Task Force. Ann Intern Med (2004) 2.53
Identification of the Fanconi anemia complementation group I gene, FANCI. Cell Oncol (2007) 2.50
The genetic and molecular basis of Fanconi anemia. Mutat Res (2008) 2.45
Deep-diving foraging behaviour of sperm whales (Physeter macrocephalus). J Anim Ecol (2006) 2.41
WDR62 is associated with the spindle pole and is mutated in human microcephaly. Nat Genet (2010) 2.40
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
The NIH genetic testing registry: a new, centralized database of genetic tests to enable access to comprehensive information and improve transparency. Nucleic Acids Res (2012) 2.35
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. Blood (2009) 2.33
INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse. Nat Genet (2009) 2.26
A double-blind randomized controlled clinical trial to assess the effect of Doppler optimized intraoperative fluid management on outcome following radical cystectomy. J Urol (2011) 2.19
Fanconi anemia and DNA replication repair. DNA Repair (Amst) (2007) 2.09
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. EMBO J (2007) 2.00
Mapping infant brain myelination with magnetic resonance imaging. J Neurosci (2011) 1.97
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. Hum Mol Genet (2004) 1.95
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome. EMBO J (2011) 1.95
Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol (2002) 1.93
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts. J Biol Chem (2008) 1.93
Control of spin precession in a spin-injected field effect transistor. Science (2009) 1.93
Fanconi anemia: adult head and neck cancer and hematopoietic mosaicism. Arch Otolaryngol Head Neck Surg (2005) 1.91
Ocular biomechanics and biotransport. Annu Rev Biomed Eng (2004) 1.91
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev (2010) 1.88
Reducing DUI among US college students: results of an environmental prevention trial. Addiction (2005) 1.87
Mechanisms and treatment of cardiovascular disease in Williams-Beuren syndrome. J Clin Invest (2008) 1.86
Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung. J Pediatr Surg (2002) 1.84
Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol (2006) 1.82
A primary microcephaly protein complex forms a ring around parental centrioles. Nat Genet (2011) 1.80
Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins. Prog Retin Eye Res (2009) 1.80
The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. Exp Eye Res (2008) 1.77
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun (2013) 1.73
Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes. Blood (2003) 1.71
The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis. Am J Hum Genet (2011) 1.71
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
The oil spill in ageing Bruch membrane. Br J Ophthalmol (2011) 1.62
Why does the bone marrow fail in Fanconi anemia? Blood (2013) 1.55
The Fanconi anemia pathway of genomic maintenance. Cell Oncol (2006) 1.52
The Human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities. J Biol Chem (2008) 1.52
Characterising the complexity of medication safety using a human factors approach: an observational study in two intensive care units. BMJ Qual Saf (2013) 1.52
Expression profiles of osteosarcoma that can predict response to chemotherapy. Cancer Res (2005) 1.49
Multidetector computed tomography in transcatheter aortic valve implantation. JACC Cardiovasc Imaging (2011) 1.47
Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. Hum Mol Genet (2009) 1.47
Centrosome function in cancer: guilty or innocent? Trends Cell Biol (2009) 1.46
BRCA1-independent ubiquitination of FANCD2. Mol Cell (2003) 1.46
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res (2011) 1.45
The mechanism of increasing outflow facility during washout in the bovine eye. Invest Ophthalmol Vis Sci (2002) 1.44
Residency training in preventive medicine: challenges and opportunities. Am J Prev Med (2005) 1.44
Evidence for subcomplexes in the Fanconi anemia pathway. Blood (2006) 1.43
CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. J Cell Biol (2010) 1.43
Should chromosome breakage studies be performed in patients with VACTERL association? Am J Med Genet A (2005) 1.42
Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1. Am J Hum Genet (2010) 1.42
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics. FEBS J (2009) 1.41
Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration. J Lipid Res (2009) 1.41
UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination. Mol Cell Biol (2007) 1.40
On-film formation of bi nanowires with extraordinary electron mobility. Nano Lett (2009) 1.38
Can the Kattan nomogram still accurately predict prognosis in renal cell carcinoma using the revised 2010 tumor-nodes-metastasis reclassification? Int J Urol (2012) 1.38
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nat Commun (2013) 1.36
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients. J Natl Cancer Inst (2008) 1.36
Quick-freeze/deep-etch visualization of age-related lipid accumulation in Bruch's membrane. Invest Ophthalmol Vis Sci (2003) 1.36
Thymic lymphomas in mice with a truncating mutation in Brca2. Cancer Res (1998) 1.36
Expression of Bcl-2 family proteins in advanced laryngeal squamous cell carcinoma: correlation with response to chemotherapy and organ preservation. Laryngoscope (2002) 1.35
Genetic subtyping of Fanconi anemia by comprehensive mutation screening. Hum Mutat (2008) 1.34
Individual right whales call louder in increased environmental noise. Biol Lett (2010) 1.31
Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice. Hum Mol Genet (2002) 1.29
Loss of centrioles causes chromosomal instability in vertebrate somatic cells. J Cell Biol (2013) 1.28
Quality of interaction between at-risk infants and caregiver at 12-15 months is associated with 3-year autism outcome. J Child Psychol Psychiatry (2012) 1.27
Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway. J Immunol (2006) 1.24
Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2. Cancer Res (2003) 1.23
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Parent-infant interaction in infant siblings at risk of autism. Res Dev Disabil (2012) 1.22
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A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Mol Cell (2012) 1.19
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Monoubiquitylation in the Fanconi anemia DNA damage response pathway. DNA Repair (Amst) (2009) 1.17