Published in Hum Exp Toxicol on February 01, 2002
A mitochondrial oscillator dependent on reactive oxygen species. Biophys J (2004) 1.99
Exogenous antioxidants-Double-edged swords in cellular redox state: Health beneficial effects at physiologic doses versus deleterious effects at high doses. Oxid Med Cell Longev (2016) 1.71
Mitochondrial criticality: a new concept at the turning point of life or death. Biochim Biophys Acta (2005) 1.68
Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxid Redox Signal (2010) 1.65
The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol Pharmacol (2008) 1.37
Non-thermal dielectric barrier discharge plasma induces angiogenesis through reactive oxygen species. J R Soc Interface (2011) 1.24
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation. Neuro Oncol (2012) 1.17
Fucoidan derived from Undaria pinnatifida induces apoptosis in human hepatocellular carcinoma SMMC-7721 cells via the ROS-mediated mitochondrial pathway. Mar Drugs (2013) 1.13
Subtoxic levels hydrogen peroxide-induced production of interleukin-6 by retinal pigment epithelial cells. Mol Vis (2010) 1.02
Sex as a response to oxidative stress: the effect of antioxidants on sexual induction in a facultatively sexual lineage. Proc Biol Sci (2003) 0.98
Oxidative Stress and Mitochondrial Dysfunction in Down's Syndrome: Relevance to Aging and Dementia. Curr Gerontol Geriatr Res (2012) 0.98
APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions. Exp Mol Med (2014) 0.97
ROS generation mediates the anti-cancer effects of WZ35 via activating JNK and ER stress apoptotic pathways in gastric cancer. Oncotarget (2015) 0.96
Pomegranate juice and punicalagin attenuate oxidative stress and apoptosis in human placenta and in human placental trophoblasts. Am J Physiol Endocrinol Metab (2012) 0.95
ROS homeostasis and metabolism: a dangerous liason in cancer cells. Cell Death Dis (2016) 0.94
Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease. World J Gastroenterol (2006) 0.94
Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes. Free Radic Biol Med (2007) 0.85
The nrf1 and nrf2 balance in oxidative stress regulation and androgen signaling in prostate cancer cells. Cancers (Basel) (2010) 0.83
A MAP kinase pathway is implicated in the pseudohyphal induction by hydrogen peroxide in Candica albicans. Mol Cells (2012) 0.83
Tumorigenic polyploid cells contain elevated ROS and ARE selectively targeted by antioxidant treatment. J Cell Physiol (2012) 0.83
Periodic Exposure of Keratinocytes to Cold Physical Plasma: An In Vitro Model for Redox-Related Diseases of the Skin. Oxid Med Cell Longev (2016) 0.82
Control of angiogenesis dictated by picomolar superoxide levels. Free Radic Biol Med (2013) 0.81
Polymorphisms in oxidative stress genes, physical activity, and breast cancer risk. Cancer Causes Control (2012) 0.80
Ascorbic Acid Attenuates Hyperoxia-Compromised Host Defense against Pulmonary Bacterial Infection. Am J Respir Cell Mol Biol (2016) 0.79
Impaired mitochondrial function due to familial Alzheimer's disease-causing presenilins mutants via Ca(2+) disruptions. Cell Calcium (2016) 0.78
Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis. Toxicol Appl Pharmacol (2014) 0.78
Increased hyaluronan levels in HABP1/p32/gC1qR overexpressing HepG2 cells inhibit autophagic vacuolation regulating tumor potency. PLoS One (2014) 0.78
A paper electrode integrated lateral flow immunosensor for quantitative analysis of oxidative stress induced DNA damage. Analyst (2014) 0.78
The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. PLoS One (2016) 0.77
TGFbeta1 expression in colonic mucosa: modulation by dietary lipids. Genes Nutr (2007) 0.77
Oxidative status in neuroblastoma: a source of stress? J Pediatr Surg (2008) 0.77
Identification of 2-oxohistidine Interacting Proteins Using E. coli Proteome Chips. Mol Cell Proteomics (2016) 0.76
Oxygen Use in Neonatal Care: A Two-edged Sword. Front Pediatr (2017) 0.76
Effects of physical activity on systemic oxidative/DNA status in breast cancer survivors. Oncol Lett (2016) 0.75
Curcuminoid EF24 enhances the anti-tumour activity of Akt inhibitor MK-2206 through ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction in gastric cancer. Br J Pharmacol (2017) 0.75
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells. Redox Biol (2017) 0.75
Emulsions Made of Oils from Seeds of GM Flax Protect V79 Cells against Oxidative Stress. Oxid Med Cell Longev (2015) 0.75
Functional implications of mitochondrial reactive oxygen species generated by oncogenic viruses. Front Biol (Beijing) (2014) 0.75
Oxidative and anti-oxidative status in muscle of young rats in response to six protein diets. Sci Rep (2017) 0.75
Proteasome inhibitor-induced cleavage of HSP90 is mediated by ROS generation and caspase 10-activation in human leukemic cells. Redox Biol (2017) 0.75
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc Natl Acad Sci U S A (1996) 4.33
KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2. Science (1995) 3.97
High-resolution serum proteomic features for ovarian cancer detection. Endocr Relat Cancer (2004) 3.75
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
New IBD genetics: common pathways with other diseases. Gut (2011) 2.95
PTEN/MMAC1 mutations in endometrial cancers. Cancer Res (1997) 2.89
Analysis of the cell population kinetics of transplanted tumours of widely-differing growth rate. Br J Cancer (1966) 2.88
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
A mathematical model of the mitotic cycle and its application to the interpretation of percentage labeled mitoses data. J Natl Cancer Inst (1966) 2.36
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res (1995) 2.35
Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res (1997) 2.34
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res (1999) 2.32
A gene involved in control of human cellular senescence on human chromosome 1q. Mol Cell Biol (1994) 2.26
Microarrays and toxicology: the advent of toxicogenomics. Mol Carcinog (1999) 2.12
Dependence of asbestos- and mineral dust-induced transformation of mammalian cells in culture on fiber dimension. Cancer Res (1984) 2.03
Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation. Cancer Res (1999) 2.02
Evidence for the progressive nature of neoplastic transformation in vitro. Proc Natl Acad Sci U S A (1978) 2.00
Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res (1997) 1.96
Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. Cancer Res (1992) 1.93
Age, time and cohort factors in mortality from cancer of the cervix. J Hyg (Lond) (1973) 1.92
DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene. Cancer Res (1999) 1.79
Induction of gene amplification by arsenic. Science (1988) 1.72
Functional overlap in mismatch repair by human MSH3 and MSH6. Genetics (1998) 1.70
Transcriptional activation of the telomerase hTERT gene by human papillomavirus type 16 E6 oncoprotein. J Virol (2001) 1.68
optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants. Bioinformatics (2012) 1.62
A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res (1998) 1.60
Avoided and avoidable risks of cancer. Carcinogenesis (1997) 1.58
PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics. Clin Cancer Res (1998) 1.58
Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes. Mol Cell Biol (1999) 1.57
Possible cellular and molecular mechanisms for asbestos carcinogenicity. Am J Ind Med (1992) 1.56
Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss. Cancer Res (1996) 1.50
Evidence for a p53-independent pathway for upregulation of SDI1/CIP1/WAF1/p21 RNA in human cells. Mol Carcinog (1994) 1.49
Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid. Biochemistry (1974) 1.49
Molecular genetic evidence of the occurrence of breast cancer as an integral tumor in patients with the hereditary nonpolyposis colorectal carcinoma syndrome. Cancer (1996) 1.48
Induction by asbestos fibers of anaphase abnormalities: mechanism for aneuploidy induction and possibly carcinogenesis. Carcinogenesis (1985) 1.46
Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias. Cancer Res (1998) 1.46
Comparison of spontaneous mutation rates of normal and chemically transformed human skin fibroblasts. Cancer Res (1983) 1.45
Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells. Cancer Res (1995) 1.44
Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radic Biol Med (2005) 1.42
Mutational analysis of the PTEN gene in human uterine sarcomas. Am J Obstet Gynecol (2001) 1.41
Methylene chloride. Science (1996) 1.40
The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: correlation with replicative bypass of platinum-DNA adducts. Cancer Res (1998) 1.39
Nonrandom loss of chromosome 15 in Syrian hamster tumours induced by v-Ha-ras plus v-myc oncogenes. Nature (1985) 1.39
Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture. Carcinogenesis (1985) 1.37
Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers. Clin Cancer Res (1995) 1.37
Breast cancer and environmental risk factors: epidemiological and experimental findings. Annu Rev Pharmacol Toxicol (1996) 1.35
Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control. Science (1991) 1.35
Temporal acquistion of enhanced fibrinolytic activity by syrian hamster embryo cells following treatment with benzo(a)pyrene. Cancer Res (1977) 1.31
Induction of cellular senescence in immortalized cells by human chromosome 1. Science (1990) 1.31
Direct isolation of human BRCA2 gene by transformation-associated recombination in yeast. Proc Natl Acad Sci U S A (1997) 1.30
Chromosome 5 suppresses tumorigenicity of PC3 prostate cancer cells: correlation with re-expression of alpha-catenin and restoration of E-cadherin function. Cancer Res (1995) 1.28
Mutation of MSH3 in endometrial cancer and evidence for its functional role in heteroduplex repair. Nat Genet (1996) 1.28
Induction of apoptosis by c-Fos protein. Mol Cell Biol (1996) 1.26
Insulin-like growth factor-I: a key regulator of human cancer risk? J Natl Cancer Inst (1999) 1.24
Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa. Mol Carcinog (1989) 1.23
Genomic organization of the human KAI1 metastasis-suppressor gene. Genomics (1997) 1.23
Correlation of asbestos-induced cytogenetic effects with cell transformation of Syrian hamster embryo cells in culture. Cancer Res (1984) 1.21
Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs. Cancer Res (1997) 1.19
Biomarkers of oxidative stress study: are plasma antioxidants markers of CCl(4) poisoning? Free Radic Biol Med (2000) 1.19
Induction of gene mutation in and cell transformation of mammalian cells by modified purines: 2-aminopurine and 6-N-hydroxylaminopurine. Proc Natl Acad Sci U S A (1981) 1.16
Regulation of microfilament organization and anchorage-independent growth by tropomyosin 1. Proc Natl Acad Sci U S A (1995) 1.16
An Alu polymorphism intragenic to the TP53 gene. Nucleic Acids Res (1991) 1.15
Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3' end target sequence. Proc Natl Acad Sci U S A (1998) 1.14
Neoplastic transformation induced by a direct perturbation of DNA. Nature (1978) 1.14
Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues. Am J Pathol (1999) 1.13
Loss of KAI1 expression in the progression of colorectal cancer. Cancer Res (1999) 1.13
A defined chromosome 6q fragment (at D6S310) harbors a putative tumor suppressor gene for breast cancer. Oncogene (1996) 1.12
Bisphenol-A induces cellular transformation, aneuploidy and DNA adduct formation in cultured Syrian hamster embryo cells. Int J Cancer (1998) 1.12
Complementation of an hMSH2 defect in human colorectal carcinoma cells by human chromosome 2 transfer. Mol Carcinog (2000) 1.12
Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes. Nucleic Acids Res (2003) 1.11
Defining a common region of deletion at 13q21 in human cancers. Genes Chromosomes Cancer (2001) 1.11
Correlation of in vitro growth properties and tumorigenicity of Syrian hamster cell lines. Cancer Res (1979) 1.10
Relationship between somatic mutation and neoplastic transformation. Proc Natl Acad Sci U S A (1978) 1.09
Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis. Oncogene (1999) 1.09
Involvement of p85 in p53-dependent apoptotic response to oxidative stress. Nature (1998) 1.07
Quantitation of fibrinolytic activity of Syrian hamster fibroblasts using 3H-labeled fibrinogen prepared by reductive alkylation. Cancer Res (1977) 1.07
Roles for insulin-like growth factor-1 in mediating the anti-carcinogenic effects of caloric restriction. J Nutr Health Aging (1999) 1.07
cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome. J Natl Cancer Inst (2001) 1.07
A mammalian cellular system for the concomitant study of neoplastic transformation and somatic mutation. Mutat Res (1978) 1.07
Genetic and cellular basis of multistep carcinogenesis. Pharmacol Ther (1990) 1.07
Diethylstilbestrol induces neoplastic transformation without measurable gene mutation at two loci. Science (1981) 1.06
Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox-9 transcription factor. Rheumatology (Oxford) (2001) 1.06
Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. Tissue Antigens (2009) 1.06
Restoration of the cellular senescence program and repression of telomerase by human chromosome 3. Jpn J Cancer Res (1995) 1.05
Estrogen upregulation of BRCA1 expression with no effect on localization. Mol Carcinog (1998) 1.05
Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells. Neoplasia (2002) 1.04
Gap junction function and cancer. Cancer Res (1993) 1.04
Chemically induced aneuploidy in mammalian cells: mechanisms and biological significance in cancer. Environ Mutagen (1986) 1.04
Regulation of p53 stability and activity in response to genotoxic stress. Mutat Res (2000) 1.04
Role of phagocytosis in Syrian hamster cell transformation and cytogenetic effects induced by asbestos and short and long glass fibers. Cancer Res (1986) 1.04
The carcinogenesis bioassay in perspective: application in identifying human cancer hazards. Environ Health Perspect (1995) 1.03
Genetic analysis of cellular senescence. Biochim Biophys Acta (1995) 1.03
Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome. Gene Ther (2008) 1.03
Growth and differentiation of hamster tracheal epithelial cells in culture. Exp Lung Res (1984) 1.03
Up-regulation of urokinase-type plasminogen activator by insulin-like growth factor-I depends upon phosphatidylinositol-3 kinase and mitogen-activated protein kinase kinase. Cancer Res (2001) 1.03
An integrated transcript map of human chromosome 1p35-p36. Genomics (1997) 1.03
Protective effect of pregnancy for development of uterine leiomyoma. Carcinogenesis (2001) 1.03
Morphologic and neoplastic transformation of Syrian hamster embryo fibroblasts by diethylstilbestrol and its analogs. Cancer Res (1982) 1.03
A hPMS2 mutant cell line is defective in strand-specific mismatch repair. J Biol Chem (1995) 1.02
Suppression of the tumorigenicity of prostatic cancer cells by gene(s) located on human chromosome 19p13.1-13.2. Prostate (1999) 1.02