Published in J Cell Biol on July 08, 2002
Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells. J Cell Biol (2008) 2.30
Nuclear transport of single molecules: dwell times at the nuclear pore complex. J Cell Biol (2005) 2.23
Nup358 integrates nuclear envelope breakdown with kinetochore assembly. J Cell Biol (2003) 2.21
Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo. Mol Biol Cell (2003) 2.12
Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurements and computer simulation. EMBO J (2003) 2.06
Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket. Mol Biol Cell (2004) 2.05
Nuclear import time and transport efficiency depend on importin beta concentration. J Cell Biol (2006) 1.84
Flexible gates: dynamic topologies and functions for FG nucleoporins in nucleocytoplasmic transport. Eukaryot Cell (2009) 1.81
Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export. Mol Cell Biol (2004) 1.70
Importin beta negatively regulates nuclear membrane fusion and nuclear pore complex assembly. Mol Biol Cell (2003) 1.62
ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing. Curr Biol (2007) 1.61
Identification and characterization of nuclear pore complex components in Arabidopsis thaliana. Plant Cell (2010) 1.59
Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes. J Cell Biol (2003) 1.52
Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes. Mol Biol Cell (2003) 1.51
Nup214 is required for CRM1-dependent nuclear protein export in vivo. Mol Cell Biol (2006) 1.46
Towards reconciling structure and function in the nuclear pore complex. Histochem Cell Biol (2008) 1.45
Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358. EMBO J (2004) 1.44
Nuclear pore proteins and cancer. Semin Cell Dev Biol (2009) 1.44
Herpesvirus capsid association with the nuclear pore complex and viral DNA release involve the nucleoporin CAN/Nup214 and the capsid protein pUL25. J Virol (2009) 1.42
The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import. Mol Biol Cell (2008) 1.40
Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates. EMBO J (2005) 1.39
Biology and biophysics of the nuclear pore complex and its components. Int Rev Cell Mol Biol (2008) 1.39
Herpes simplex virus replication: roles of viral proteins and nucleoporins in capsid-nucleus attachment. J Virol (2008) 1.33
HIV infection of non-dividing cells: a divisive problem. Retrovirology (2006) 1.33
Visualizing single molecules interacting with nuclear pore complexes by narrow-field epifluorescence microscopy. Methods (2006) 1.30
Nup53 is required for nuclear envelope and nuclear pore complex assembly. Mol Biol Cell (2008) 1.29
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. EMBO J (2012) 1.27
RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export. Mol Cell Biol (2004) 1.26
Reticulon 4a/NogoA locates to regions of high membrane curvature and may have a role in nuclear envelope growth. J Struct Biol (2007) 1.26
RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet (2006) 1.23
Identification and functional clustering of global gene expression differences between human age-related cataract and clear lenses. Mol Vis (2003) 1.21
The FG-repeat asymmetry of the nuclear pore complex is dispensable for bulk nucleocytoplasmic transport in vivo. J Cell Biol (2004) 1.20
Specific cleavage of the nuclear pore complex protein Nup62 by a viral protease. J Biol Chem (2010) 1.13
Proteins of the PIAS family enhance the sumoylation of the papillomavirus E1 protein. Virology (2005) 1.13
Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration. PLoS One (2012) 1.12
In situ structural analysis of the human nuclear pore complex. Nature (2015) 1.10
The oncogene eIF4E reprograms the nuclear pore complex to promote mRNA export and oncogenic transformation. Cell Rep (2012) 1.08
Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability. J Cell Biol (2011) 1.07
Distinct functions of the Drosophila Nup153 and Nup214 FG domains in nuclear protein transport. J Cell Biol (2007) 1.07
Nuclear envelope breakdown is coordinated by both Nup358/RanBP2 and Nup153, two nucleoporins with zinc finger modules. Mol Biol Cell (2005) 1.06
From the trap to the basket: getting to the bottom of the nuclear pore complex. Chromosoma (2006) 1.06
Biochemical characterization of the Ran-RanBP1-RanGAP system: are RanBP proteins and the acidic tail of RanGAP required for the Ran-RanGAP GTPase reaction? Mol Cell Biol (2003) 1.02
HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358. Retrovirology (2013) 1.01
Mice lacking the nuclear pore complex protein ALADIN show female infertility but fail to develop a phenotype resembling human triple A syndrome. Mol Cell Biol (2006) 0.99
Brownian dynamics simulation of nucleocytoplasmic transport: a coarse-grained model for the functional state of the nuclear pore complex. PLoS Comput Biol (2011) 0.99
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity. Elife (2015) 0.98
The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity. J Cell Biol (2011) 0.94
Single-molecule studies of nucleocytoplasmic transport: from one dimension to three dimensions. Integr Biol (Camb) (2011) 0.94
A supraphysiological nuclear export signal is required for parvovirus nuclear export. Mol Biol Cell (2008) 0.91
Transportin mediates nuclear entry of DNA in vertebrate systems. Traffic (2009) 0.90
Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation. J Biol Chem (2014) 0.90
High-resolution three-dimensional mapping of mRNA export through the nuclear pore. Nat Commun (2013) 0.89
Aiding and abetting cancer: mRNA export and the nuclear pore. Trends Cell Biol (2013) 0.88
The nuclear pore complex protein Tpr is a common autoantigen in sera that demonstrate nuclear envelope staining by indirect immunofluorescence. Clin Exp Immunol (2004) 0.88
Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains. Mol Cell Biol (2002) 0.88
Cdk1 Activates Pre-mitotic Nuclear Envelope Dynein Recruitment and Apical Nuclear Migration in Neural Stem Cells. Dev Cell (2015) 0.88
Three siblings with triple A syndrome with a novel frameshift mutation in the AAAS gene and a review of 17 independent patients with the frequent p.Ser263Pro mutation. Eur J Pediatr (2008) 0.88
Importin beta-depending nuclear import pathways: role of the adapter proteins in the docking and releasing steps. Mol Biol Cell (2003) 0.88
The nucleoporin Nup88 is interacting with nuclear lamin A. Mol Biol Cell (2011) 0.84
Dynamics and diverse functions of nuclear pore complex proteins. Nucleus (2012) 0.84
The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2. Mol Biol Cell (2012) 0.83
Nuclear import of an intact preassembled proteasome particle. Mol Biol Cell (2011) 0.83
Choreography of importin-α/CAS complex assembly and disassembly at nuclear pores. Proc Natl Acad Sci U S A (2013) 0.82
Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1. J Biol Chem (2012) 0.79
Calcium regulation of nucleocytoplasmic transport. Protein Cell (2011) 0.79
Selective Removal of FG Repeat Domains from the Nuclear Pore Complex by Enterovirus 2Apro. J Virol (2015) 0.77
Quantitative topographical analysis of nuclear pore complex function using scanning force microscopy. Biophys J (2003) 0.77
High-resolution imaging reveals new features of nuclear export of mRNA through the nuclear pore complexes. Int J Mol Sci (2014) 0.77
The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget (2014) 0.76
Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2). FEBS Lett (2015) 0.75
Cooperative Interactions between Different Classes of Disordered Proteins Play a Functional Role in the Nuclear Pore Complex of Baker's Yeast. PLoS One (2017) 0.75
The Ran Pathway in Drosophila melanogaster Mitosis. Front Cell Dev Biol (2015) 0.75
Regulation of aPKC activity by Nup358 dependent SUMO modification. Sci Rep (2016) 0.75
The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol (2000) 10.20
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell (1997) 9.01
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol (1996) 7.64
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Movement of a karyophilic protein through the nuclear pores of oocytes. J Cell Biol (1984) 6.51
Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs. Cell (1986) 5.96
The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell (2002) 5.80
Identification of different roles for RanGDP and RanGTP in nuclear protein import. EMBO J (1996) 5.53
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The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. EMBO J (1997) 4.65
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell (1995) 4.55
Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. J Biol Chem (1995) 4.50
A giant nucleopore protein that binds Ran/TC4. Nature (1995) 4.36
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A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm. Cell (1993) 3.98
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SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex. J Cell Biol (1998) 3.65
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The essential yeast nucleoporin NUP159 is located on the cytoplasmic side of the nuclear pore complex and serves in karyopherin-mediated binding of transport substrate. J Biol Chem (1995) 2.39
Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain. EMBO J (1999) 2.37
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Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments. J Cell Biol (1997) 2.32
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RanBP1 stabilizes the interaction of Ran with p97 nuclear protein import. J Cell Biol (1996) 2.19
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The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. EMBO J (2001) 2.14
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Reconstituted nuclei depleted of a vertebrate GLFG nuclear pore protein, p97, import but are defective in nuclear growth and replication. J Cell Biol (1995) 2.11
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Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Mol Biol Cell (1995) 2.04
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ATP-Induced shape change of nuclear pores visualized with the atomic force microscope. J Membr Biol (1998) 0.97
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Energy- and temperature-dependent in vitro export of RNA from synthetic nuclei. Biol Chem (1997) 0.87
The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome. J Biol Chem (1998) 0.84
The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Cell (2003) 3.58
Characterization of the Drosophila melanogaster genome at the nuclear lamina. Nat Genet (2006) 3.44
A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes. Nat Cell Biol (2006) 3.09
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Pushing the envelope: structure, function, and dynamics of the nuclear periphery. Annu Rev Cell Dev Biol (2005) 2.95
Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm. Cell (2010) 2.80
HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol (2006) 2.74
Nonprocessive methylation by Dot1 leads to functional redundancy of histone H3K79 methylation states. Nat Struct Mol Biol (2008) 2.27
MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly. EMBO Rep (2007) 2.18
HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore. EMBO J (2007) 2.17
Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo. Mol Biol Cell (2003) 2.12
Large-scale induced fit recognition of an m(7)GpppG cap analogue by the human nuclear cap-binding complex. EMBO J (2002) 2.10
RanGTP mediates nuclear pore complex assembly. Nature (2003) 2.08
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol (2010) 2.07
Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket. Mol Biol Cell (2004) 2.05
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly. Nat Cell Biol (2002) 2.05
The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells. Mol Cell (2006) 2.04
The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia. Blood (2008) 1.95
Direct interaction with nup153 mediates binding of Tpr to the periphery of the nuclear pore complex. Mol Biol Cell (2003) 1.91
The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation. Mol Cell (2005) 1.85
Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly. EMBO J (2006) 1.81
Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging. Science (2013) 1.80
The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins. PLoS Biol (2010) 1.78
Importin alpha-regulated nucleation of microtubules by TPX2. EMBO J (2003) 1.77
MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegans. Curr Biol (2006) 1.74
Architecture of CRM1/Exportin1 suggests how cooperativity is achieved during formation of a nuclear export complex. Mol Cell (2004) 1.72
Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export. Mol Cell Biol (2004) 1.70
Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos. Mol Biol Cell (2002) 1.69
NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes. J Cell Biol (2006) 1.67
The inner nuclear envelope as a transcription factor resting place. EMBO Rep (2007) 1.61
Coaligned dual-channel STED nanoscopy and molecular diffusion analysis at 20 nm resolution. Biophys J (2013) 1.46
Direct membrane protein-DNA interactions required early in nuclear envelope assembly. J Cell Biol (2006) 1.46
Supraphysiological nuclear export signals bind CRM1 independently of RanGTP and arrest at Nup358. EMBO J (2004) 1.44
Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway. J Cell Sci (2008) 1.39
Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates. EMBO J (2005) 1.39
The SMN complex is associated with snRNPs throughout their cytoplasmic assembly pathway. Mol Cell Biol (2002) 1.39
Identity elements used in export of mRNAs. Mol Cell (2002) 1.37
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis. Dev Cell (2005) 1.30
A role for the dynamin-like protein Vps1 during endocytosis in yeast. J Cell Sci (2010) 1.29
RanBP3 enhances nuclear export of active (beta)-catenin independently of CRM1. J Cell Biol (2005) 1.29
Nup53 is required for nuclear envelope and nuclear pore complex assembly. Mol Biol Cell (2008) 1.29
Ran binds to chromatin by two distinct mechanisms. Curr Biol (2002) 1.27
Reticulon 4a/NogoA locates to regions of high membrane curvature and may have a role in nuclear envelope growth. J Struct Biol (2007) 1.26
Actin- and protein-4.1-containing filaments link nuclear pore complexes to subnuclear organelles in Xenopus oocyte nuclei. J Cell Sci (2004) 1.25
Venezuelan equine Encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin alpha/beta that obstructs nuclear pore complex function. J Virol (2010) 1.25
The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export. J Cell Biol (2003) 1.24
Protein Tpr is required for establishing nuclear pore-associated zones of heterochromatin exclusion. EMBO J (2010) 1.22
Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. J Cell Biol (2009) 1.22
Lipin is required for efficient breakdown of the nuclear envelope in Caenorhabditis elegans. J Cell Sci (2009) 1.22
Nuclear envelope and nuclear pore complex structure and organization in tobacco BY-2 cells. Plant J (2009) 1.20
Nuclear pore complex assembly and maintenance in POM121- and gp210-deficient cells. J Cell Biol (2006) 1.20
Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis. Cell (2012) 1.19
Three-dimensional reconstruction of bacteria with a complex endomembrane system. PLoS Biol (2013) 1.19
Yeast nuclear pore complexes have a cytoplasmic ring and internal filaments. J Struct Biol (2004) 1.17
The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex. Mol Biol Cell (2009) 1.15
Importin alpha associates with membranes and participates in nuclear envelope assembly in vitro. EMBO J (2004) 1.14
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol (2008) 1.13
Samp1 is a component of TAN lines and is required for nuclear movement. J Cell Sci (2012) 1.11
The inner nuclear membrane protein Lem2 is critical for normal nuclear envelope morphology. FEBS Lett (2006) 1.09
A role for NuSAP in linking microtubules to mitotic chromosomes. Curr Biol (2007) 1.08
Co-crystallization of the human nuclear cap-binding complex with a m7GpppG cap analogue using protein engineering. Acta Crystallogr D Biol Crystallogr (2002) 1.07
FGF-2 release from the lens capsule by MMP-2 maintains lens epithelial cell viability. Mol Biol Cell (2007) 1.07
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Homodimerization antagonizes nuclear export of survivin. Traffic (2007) 1.04
Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly. Eur J Cell Biol (2002) 1.03
Yeast dynamin Vps1 and amphiphysin Rvs167 function together during endocytosis. Traffic (2011) 1.03
Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope. Cell Mol Life Sci (2010) 1.02
Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export. J Biol Chem (2006) 1.02
System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics. J Cell Biol (2011) 1.01
The strategy for coupling the RanGTP gradient to nuclear protein export. Proc Natl Acad Sci U S A (2003) 1.00
Mitotic lamin disassembly is triggered by lipid-mediated signaling. J Cell Biol (2012) 1.00
Facilitated transport and diffusion take distinct spatial routes through the nuclear pore complex. J Cell Sci (2010) 1.00
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Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore. Mol Cell (2008) 0.98
The evolutionarily conserved single-copy gene for murine Tpr encodes one prevalent isoform in somatic cells and lacks paralogs in higher eukaryotes. Chromosoma (2002) 0.97
Nup153 affects entry of messenger and ribosomal ribonucleoproteins into the nuclear basket during export. Mol Biol Cell (2005) 0.97
NLS-mediated NPC functions of the nucleoporin Pom121. FEBS Lett (2010) 0.95
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40LoVe interacts with Vg1RBP/Vera and hnRNP I in binding the Vg1-localization element. RNA (2005) 0.93
Characterization of genome-nucleoporin interactions in Drosophila links chromatin insulators to the nuclear pore complex. Cell Cycle (2010) 0.93
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A supraphysiological nuclear export signal is required for parvovirus nuclear export. Mol Biol Cell (2008) 0.91
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