| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases.
|
Hepatology
|
2012
|
3.94
|
|
2
|
The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.
|
Hepatology
|
2008
|
2.99
|
|
3
|
IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.
|
J Clin Invest
|
2012
|
2.64
|
|
4
|
Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial.
|
Hepatology
|
2008
|
2.44
|
|
5
|
Signalling pathways in alcohol-induced liver inflammation.
|
J Hepatol
|
2009
|
2.29
|
|
6
|
Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation.
|
Gastroenterology
|
2004
|
2.16
|
|
7
|
Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease.
|
J Biol Chem
|
2010
|
2.16
|
|
8
|
Cytokines and alcohol.
|
Alcohol Clin Exp Res
|
2006
|
2.04
|
|
9
|
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells.
|
Hepatology
|
2011
|
2.04
|
|
10
|
Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.
|
Hepatology
|
2011
|
1.98
|
|
11
|
Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus.
|
J Virol
|
2009
|
1.92
|
|
12
|
Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.
|
J Immunol
|
2006
|
1.82
|
|
13
|
Human type 2 myeloid dendritic cells produce interferon-λ and amplify interferon-α in response to hepatitis C virus infection.
|
Gastroenterology
|
2012
|
1.80
|
|
14
|
Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection.
|
Gastroenterology
|
2007
|
1.71
|
|
15
|
The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes.
|
J Immunol
|
2009
|
1.70
|
|
16
|
Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation.
|
J Immunol
|
2003
|
1.64
|
|
17
|
MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice.
|
Alcohol Clin Exp Res
|
2009
|
1.61
|
|
18
|
Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.
|
J Leukoc Biol
|
2007
|
1.61
|
|
19
|
An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.
|
Hepatology
|
2011
|
1.60
|
|
20
|
Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice.
|
Gastroenterology
|
2010
|
1.56
|
|
21
|
Innate immunity in alcoholic liver disease.
|
Am J Physiol Gastrointest Liver Physiol
|
2011
|
1.55
|
|
22
|
STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease.
|
Proc Natl Acad Sci U S A
|
2013
|
1.53
|
|
23
|
Factors that determine the development and progression of gastroesophageal varices in patients with chronic hepatitis C.
|
Gastroenterology
|
2010
|
1.52
|
|
24
|
VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.
|
Hepatology
|
2009
|
1.47
|
|
25
|
Emerging role of microRNAs in liver diseases.
|
World J Gastroenterol
|
2009
|
1.45
|
|
26
|
TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.
|
J Immunol
|
2006
|
1.43
|
|
27
|
Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.
|
Hepatology
|
2011
|
1.40
|
|
28
|
Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10.
|
Alcohol Clin Exp Res
|
2006
|
1.35
|
|
29
|
Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.
|
PLoS Pathog
|
2012
|
1.35
|
|
30
|
Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.
|
Am J Physiol Gastrointest Liver Physiol
|
2011
|
1.35
|
|
31
|
A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C.
|
Hepatology
|
2011
|
1.33
|
|
32
|
Hypoxia and hypoxia inducible factors: diverse roles in liver diseases.
|
Hepatology
|
2012
|
1.32
|
|
33
|
Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes.
|
J Immunol
|
2006
|
1.29
|
|
34
|
Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection.
|
J Transl Med
|
2012
|
1.28
|
|
35
|
Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts.
|
Alcohol Clin Exp Res
|
2006
|
1.24
|
|
36
|
Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes.
|
Alcohol Clin Exp Res
|
2008
|
1.23
|
|
37
|
Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury.
|
J Hepatol
|
2006
|
1.22
|
|
38
|
Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production.
|
J Immunol
|
2004
|
1.20
|
|
39
|
Acute and chronic alcohol abuse modulate immunity.
|
Alcohol Clin Exp Res
|
2006
|
1.18
|
|
40
|
Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes.
|
J Leukoc Biol
|
2007
|
1.17
|
|
41
|
Binge ethanol and liver: new molecular developments.
|
Alcohol Clin Exp Res
|
2013
|
1.13
|
|
42
|
MicroRNA Signature in Alcoholic Liver Disease.
|
Int J Hepatol
|
2012
|
1.12
|
|
43
|
Myeloid dendritic cells of patients with chronic HCV infection induce proliferation of regulatory T lymphocytes.
|
Gastroenterology
|
2008
|
1.11
|
|
44
|
Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver.
|
Hepatology
|
2004
|
1.10
|
|
45
|
Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.
|
J Leukoc Biol
|
2013
|
1.10
|
|
46
|
Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells.
|
Hepatology
|
2010
|
1.09
|
|
47
|
Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver.
|
World J Gastroenterol
|
2011
|
1.07
|
|
48
|
Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice.
|
Hepatology
|
2004
|
1.06
|
|
49
|
Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity.
|
Semin Liver Dis
|
2009
|
1.02
|
|
50
|
Alcohol exposure as a risk factor for adverse outcomes in elective surgery.
|
J Gastrointest Surg
|
2010
|
1.01
|
|
51
|
Distinct Toll-like receptor expression in monocytes and T cells in chronic HCV infection.
|
World J Gastroenterol
|
2006
|
1.01
|
|
52
|
Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IkappaB kinase activity and p65 phosphorylation in human monocytes.
|
J Immunol
|
2007
|
1.01
|
|
53
|
Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion.
|
Hepatology
|
2008
|
1.01
|
|
54
|
Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction.
|
Alcohol Clin Exp Res
|
2003
|
1.00
|
|
55
|
Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells.
|
PLoS One
|
2012
|
1.00
|
|
56
|
Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics.
|
Am J Respir Crit Care Med
|
2006
|
0.98
|
|
57
|
Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation?
|
Alcohol Clin Exp Res
|
2002
|
0.96
|
|
58
|
Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice.
|
Hepatology
|
2011
|
0.95
|
|
59
|
Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice.
|
PLoS One
|
2013
|
0.94
|
|
60
|
IFN-γ production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells.
|
J Hepatol
|
2013
|
0.94
|
|
61
|
Dendritic cells in hepatitis C infection: can they (help) win the battle?
|
J Gastroenterol
|
2011
|
0.94
|
|
62
|
In vitro and in vivo models of acute alcohol exposure.
|
World J Gastroenterol
|
2009
|
0.93
|
|
63
|
Toll-like receptors in liver disease.
|
Adv Clin Chem
|
2013
|
0.93
|
|
64
|
CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus-infected cells and induction of interferon-alpha.
|
Hepatology
|
2013
|
0.93
|
|
65
|
Toll-like receptors in the pathogenesis of alcoholic liver disease.
|
Gastroenterol Res Pract
|
2010
|
0.93
|
|
66
|
T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't.
|
J Leukoc Biol
|
2008
|
0.93
|
|
67
|
Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes.
|
J Leukoc Biol
|
2005
|
0.92
|
|
68
|
Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells.
|
Hepatology
|
2013
|
0.92
|
|
69
|
Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.
|
Hepatology
|
2013
|
0.91
|
|
70
|
Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes.
|
BMC Immunol
|
2011
|
0.90
|
|
71
|
The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.
|
Alcohol Clin Exp Res
|
2012
|
0.90
|
|
72
|
Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance.
|
J Leukoc Biol
|
2012
|
0.89
|
|
73
|
Antigen-presenting cells under the influence of alcohol.
|
Trends Immunol
|
2008
|
0.89
|
|
74
|
Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells.
|
Alcohol Clin Exp Res
|
2012
|
0.89
|
|
75
|
microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis.
|
Liver Int
|
2014
|
0.89
|
|
76
|
Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression.
|
Alcohol Clin Exp Res
|
2005
|
0.88
|
|
77
|
Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone.
|
Dig Dis Sci
|
2002
|
0.87
|
|
78
|
Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis.
|
Liver Int
|
2014
|
0.86
|
|
79
|
Plasma microRNA profiles distinguish lethal injury in acetaminophen toxicity: a research study.
|
World J Gastroenterol
|
2012
|
0.85
|
|
80
|
Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in mice.
|
Alcohol Clin Exp Res
|
2014
|
0.85
|
|
81
|
Hepatitis C virus NS5A protein--a master regulator?
|
Gastroenterology
|
2006
|
0.82
|
|
82
|
FcgammaR cross-linking mediates NF-kappaB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development.
|
J Leukoc Biol
|
2002
|
0.81
|
|
83
|
Hepatitis C core protein - the "core" of immune deception?
|
J Hepatol
|
2007
|
0.81
|
|
84
|
The emerging role of toll-like receptor pathways in surgical diseases.
|
Arch Surg
|
2006
|
0.80
|
|
85
|
Inhibition of NF-kappa B binding correlates with increased nuclear glucocorticoid receptor levels in acute alcohol-treated human monocytes.
|
Alcohol Clin Exp Res
|
2002
|
0.80
|
|
86
|
Differences in innate immune signaling between alcoholic and non-alcoholic steatohepatitis.
|
J Gastroenterol Hepatol
|
2013
|
0.79
|
|
87
|
Novel developmental biology-based protocol of embryonic stem cell differentiation to morphologically sound and functional yet immature hepatocytes.
|
Liver Int
|
2012
|
0.79
|
|
88
|
The genetics of hepatitis C virus underlie its ability to escape humoral immunity.
|
J Clin Invest
|
2014
|
0.78
|
|
89
|
Reduction in Hepatic Inflammation Is Associated With Less Fibrosis Progression and Fewer Clinical Outcomes in Advanced Hepatitis C.
|
Am J Gastroenterol
|
2012
|
0.78
|
|
90
|
Another armed CD4(+) T cell ready to battle hepatocellular carcinoma.
|
Hepatology
|
2013
|
0.78
|
|
91
|
The 40th anniversary of the National Institute on Alcoholism and Alcohol Abuse: the impact on liver disease.
|
Hepatology
|
2010
|
0.77
|
|
92
|
Modulation of immunity and viral-host interactions by alcohol.
|
Alcohol Clin Exp Res
|
2002
|
0.76
|
|
93
|
Advanced molecular biologic techniques in toxicologic disease.
|
J Med Toxicol
|
2011
|
0.75
|
|
94
|
Reply: To PMID 22684891.
|
Hepatology
|
2013
|
0.75
|
|
95
|
Hepatitis C virus infection--pathobiology and implications for new therapeutic options.
|
Dig Dis Sci
|
2007
|
0.75
|
|
96
|
RSA 2004: combined basic research satellite symposium - session two: toll-like receptors and organ damage.
|
Alcohol Clin Exp Res
|
2005
|
0.75
|
|
97
|
Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice.
|
PLoS One
|
2017
|
0.75
|