Published in Blood on August 15, 2002
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer (2009) 18.53
Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer (2013) 6.13
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines. Br J Cancer (2006) 2.74
Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury. J Clin Invest (2004) 1.85
SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype. BMC Cancer (2010) 1.56
Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression. J Mammary Gland Biol Neoplasia (2004) 1.33
Transcription factor binding dynamics during human ES cell differentiation. Nature (2015) 1.30
An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm. PLoS One (2006) 1.09
Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood-derived hematopoietic progenitor cells. Blood (2008) 1.08
Molecular biology of adenoid cystic carcinoma. Head Neck (2011) 1.07
Regulation of cell junction dynamics by cytokines in the testis: a molecular and biochemical perspective. Cytokine Growth Factor Rev (2007) 1.06
Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression. Cell Death Differ (2014) 1.05
Hoxa-10 deficiency alters region-specific gene expression and perturbs differentiation of natural killer cells during decidualization. Dev Biol (2005) 1.04
Cancer as a reprogramming-like disease: implications in tumor development and treatment. Semin Cancer Biol (2010) 1.03
Sustained proliferation in cancer: Mechanisms and novel therapeutic targets. Semin Cancer Biol (2015) 1.01
Slug expression during melanoma progression. Am J Pathol (2012) 0.97
SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts. BMC Mol Biol (2010) 0.95
A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. Mol Cell (2014) 0.94
Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice. Mol Cell Biol (2007) 0.93
Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency. PLoS One (2013) 0.92
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. EMBO J (2015) 0.92
Role of miRNA let-7 and its major targets in prostate cancer. Biomed Res Int (2014) 0.89
Neural crest as the source of adult stem cells. Stem Cells Dev (2006) 0.89
Stem cell factor expression after renal ischemia promotes tubular epithelial survival. PLoS One (2010) 0.89
Slug deficiency enhances self-renewal of hematopoietic stem cells during hematopoietic regeneration. Blood (2009) 0.87
Snai2 expression enhances ultraviolet radiation-induced skin carcinogenesis. Am J Pathol (2007) 0.86
C-kit induces epithelial-mesenchymal transition and contributes to salivary adenoid cystic cancer progression. Oncotarget (2014) 0.86
Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2). Br J Cancer (2008) 0.86
Genome-wide mapping of loci explaining variance in scrotal circumference in Nellore cattle. PLoS One (2014) 0.85
Overexpression of Snai3 suppresses lymphoid- and enhances myeloid-cell differentiation. Eur J Immunol (2012) 0.85
Gut stem cells, a story of snails, flies and mice. EMBO J (2015) 0.79
KIT is required for hepatic function during mouse post-natal development. BMC Dev Biol (2007) 0.79
Allelic Mutations of KITLG, Encoding KIT Ligand, Cause Asymmetric and Unilateral Hearing Loss and Waardenburg Syndrome Type 2. Am J Hum Genet (2015) 0.78
Snail transcription factors in hematopoietic cell development: a model of functional redundancy. Exp Hematol (2014) 0.78
New functions for the Snail family of transcription factors: Two-faced proteins. Cell Cycle (2010) 0.77
The mesenchymal transcription factor SNAI-1 instructs human liver specification. Stem Cell Res (2016) 0.76
Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3. Cell Immunol (2015) 0.76
A novel slug-containing negative-feedback loop regulates SCF/c-Kit-mediated hematopoietic stem cell self-renewal. Leukemia (2016) 0.75
Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors. Carcinogenesis (2015) 0.75
Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells. Drug Des Devel Ther (2016) 0.75
Inhibition of Snail Family Transcriptional Repressor 2 (SNAI2) Enhances Multidrug Resistance of Hepatocellular Carcinoma Cells. PLoS One (2016) 0.75
Should we consider cancers as embryonic diseases or as consequences of stem-cell deregulation? Clin Med Oncol (2008) 0.75
SLUG transcription factor: a pro-survival and prognostic factor in gastrointestinal stromal tumour. Br J Cancer (2017) 0.75
Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders. Haematologica (2008) 2.99
Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference. Leuk Res (2007) 2.97
Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation. Blood (2008) 2.74
Clinical benefit associated with idiotypic vaccination in patients with follicular lymphoma. J Natl Cancer Inst (2006) 2.69
Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification. Blood (2011) 2.14
Identification and molecular characterization of the mammalian α-kleisin RAD21L. Cell Cycle (2011) 1.86
Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma. J Clin Oncol (2011) 1.78
TWIST1 promotes invasion through mesenchymal change in human glioblastoma. Mol Cancer (2010) 1.73
Deletion of the SLUG (SNAI2) gene results in human piebaldism. Am J Med Genet A (2003) 1.72
SLUG (SNAI2) deletions in patients with Waardenburg disease. Hum Mol Genet (2002) 1.64
Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal. Int Arch Allergy Immunol (2011) 1.63
Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. Blood (2009) 1.62
Expanded cells in monoclonal TCR-alphabeta+/CD4+/NKa+/CD8-/+dim T-LGL lymphocytosis recognize hCMV antigens. Blood (2008) 1.61
Circulating human B and plasma cells. Age-associated changes in counts and detailed characterization of circulating normal CD138- and CD138+ plasma cells. Haematologica (2010) 1.61
Differences in anti-apoptotic and multidrug resistance phenotypes in elderly and young acute myeloid leukemia patients are related to the maturation of blast cells. Haematologica (2005) 1.56
Prognostic value of immunophenotyping in multiple myeloma: a study by the PETHEMA/GEM cooperative study groups on patients uniformly treated with high-dose therapy. J Clin Oncol (2008) 1.53
Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO J (2008) 1.52
Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice. Genes Dev (2008) 1.49
Function of the zinc-finger transcription factor SNAI2 in cancer and development. Annu Rev Genet (2007) 1.46
Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms. J Allergy Clin Immunol (2010) 1.46
Long-term effects of mouse intracytoplasmic sperm injection with DNA-fragmented sperm on health and behavior of adult offspring. Biol Reprod (2008) 1.45
Different subsets of peripheral blood dendritic cells show distinct phenotypic and functional abnormalities in HIV-1 infection. AIDS (2005) 1.44
The incorporation of quantum effects in enzyme kinetics modeling. Acc Chem Res (2002) 1.44
Hodgkin and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: analyses using tissue microarrays. Blood (2002) 1.44
SLUG in cancer development. Oncogene (2005) 1.42
Standardization of flow cytometry in myelodysplastic syndromes: report from the first European LeukemiaNet working conference on flow cytometry in myelodysplastic syndromes. Haematologica (2009) 1.40
Utility of flow cytometry immunophenotyping in multiple myeloma and other clonal plasma cell-related disorders. Cytometry B Clin Cytom (2010) 1.36
The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility. EMBO J (2011) 1.34
The radioresistance biological function of the SCF/kit signaling pathway is mediated by the zinc-finger transcription factor Slug. Oncogene (2003) 1.26
Prognostic and biologic significance of chromosomal imbalances assessed by comparative genomic hybridization in multiple myeloma. Blood (2004) 1.26
B-cell acute lymphoblastic leukaemia: towards understanding its cellular origin. Bioessays (2009) 1.24
Meiotic cohesin complexes are essential for the formation of the axial element in mice. J Cell Biol (2012) 1.23
The nature of circulating CD27+CD43+ B cells. J Exp Med (2011) 1.22
Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes. J Allergy Clin Immunol (2010) 1.22
Identification of leptomeningeal disease in aggressive B-cell non-Hodgkin's lymphoma: improved sensitivity of flow cytometry. J Clin Oncol (2009) 1.21
Genetic abnormalities and patterns of antigenic expression in multiple myeloma. Clin Cancer Res (2005) 1.21
Conventional diagnostics in multiple myeloma. Eur J Cancer (2006) 1.20
Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model. J Biol Chem (2005) 1.19
Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice. Proc Natl Acad Sci U S A (2012) 1.19
Cancer development induced by graded expression of Snail in mice. Hum Mol Genet (2005) 1.18
Snail family transcription factors are implicated in thyroid carcinogenesis. Am J Pathol (2007) 1.17
Generation of flow cytometry data files with a potentially infinite number of dimensions. Cytometry A (2008) 1.16
Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients. J Allergy Clin Immunol (2009) 1.15
Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile. Blood (2013) 1.15
CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype. Haematologica (2012) 1.14
Immunogenetics shows that not all MBL are equal: the larger the clone, the more similar to CLL. Blood (2013) 1.14
Dermoscopic features of skin lesions in patients with mastocytosis. Arch Dermatol (2011) 1.14
Risk of progression in smouldering myeloma and monoclonal gammopathies of unknown significance: comparative analysis of the evolution of monoclonal component and multiparameter flow cytometry of bone marrow plasma cells. Br J Haematol (2009) 1.13
A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors. EMBO J (2012) 1.12
Bone marrow cells from myelodysplastic syndromes show altered immunophenotypic profiles that may contribute to the diagnosis and prognostic stratification of the disease: a pilot study on a series of 56 patients. Cytometry B Clin Cytom (2010) 1.12
Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma. Proc Natl Acad Sci U S A (2013) 1.11
Stem-cell driven cancer: "hands-off" regulation of cancer development. Cell Cycle (2009) 1.10
[Diagnosis and treatment of nocturnal paroxysmal hemoglobinuria]. Med Clin (Barc) (2010) 1.10
Flow cytometry criteria for systemic mastocytosis: bone marrow mast cell counts do not always count. Am J Clin Pathol (2013) 1.10
Quantitative analysis of the expression of glycosylphosphatidylinositol-anchored proteins during the maturation of different hematopoietic cell compartments of normal bone marrow. Cytometry B Clin Cytom (2007) 1.10
Multiparameter flow cytometry quantification of bone marrow plasma cells at diagnosis provides more prognostic information than morphological assessment in myeloma patients. Haematologica (2009) 1.08
Essential role for telomerase in chronic myeloid leukemia induced by BCR-ABL in mice. Oncotarget (2012) 1.07
Systemic mastocytosis as a risk factor for severe Hymenoptera sting-induced anaphylaxis. J Allergy Clin Immunol (2012) 1.07
Flow cytometry in myelodysplastic syndromes: report from a working conference. Leuk Res (2007) 1.06
Minimal residual disease in adolescent (older than 14 years) and adult acute lymphoblastic leukemias: early immunophenotypic evaluation has high clinical value. Blood (2003) 1.06
TCRalphabeta+/CD4+ large granular lymphocytosis: a new clonal T-cell lymphoproliferative disorder. Am J Pathol (2003) 1.05
Mouse cDNA microarray analysis uncovers Slug targets in mouse embryonic fibroblasts. Genomics (2005) 1.05
The endoplasmic reticulum of dorsal root ganglion neurons contains functional TRPV1 channels. J Biol Chem (2009) 1.04
Incidence and clinicobiologic characteristics of leukemic B-cell chronic lymphoproliferative disorders with more than one B-cell clone. Blood (2003) 1.04
The age of the target cell affects B-cell leukaemia malignancy. Aging (Albany NY) (2010) 1.04
Patient gender is associated with distinct patterns of chromosomal abnormalities and sex chromosome linked gene-expression profiles in meningiomas. Oncologist (2007) 1.04
Incidence and characteristics of CD4(+)/HLA DRhi dendritic cell malignancies. Haematologica (2004) 1.04
Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry. Haematologica (2012) 1.04
Flow cytometric immunophenotyping of cerebrospinal fluid. Curr Protoc Cytom (2008) 1.03
Cancer as a reprogramming-like disease: implications in tumor development and treatment. Semin Cancer Biol (2010) 1.03
Evaluation of multiparameter flow cytometry for the detection of breast cancer tumor cells in blood samples. Am J Clin Pathol (2005) 1.03
Function of oncogenes in cancer development: a changing paradigm. EMBO J (2013) 1.02
Overview of clinical flow cytometry data analysis: recent advances and future challenges. Trends Biotechnol (2013) 1.01
Evaluation of the WHO criteria for the classification of patients with mastocytosis. Mod Pathol (2011) 1.01
Immunophenotypic analysis of mast cells in mastocytosis: When and how to do it. Proposals of the Spanish Network on Mastocytosis (REMA). Cytometry B Clin Cytom (2004) 1.01
Chronic alcohol consumption is associated with changes in the distribution, immunophenotype, and the inflammatory cytokine secretion profile of circulating dendritic cells. Alcohol Clin Exp Res (2007) 1.01
Proposal for a new risk stratification classification for meningioma based on patient age, WHO tumor grade, size, localization, and karyotype. Neuro Oncol (2014) 1.00