Published in J Biol Chem on July 31, 2002
Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots. J Virol (2002) 2.50
HIV-1 antiretroviral drug therapy. Cold Spring Harb Perspect Med (2012) 2.18
Nature, position, and frequency of mutations made in a single cycle of HIV-1 replication. J Virol (2010) 1.65
APOBEC3G contributes to HIV-1 variation through sublethal mutagenesis. J Virol (2010) 1.58
HIV-1 reverse transcription. Cold Spring Harb Perspect Med (2012) 1.29
Mutation rates and intrinsic fidelity of retroviral reverse transcriptases. Viruses (2009) 1.19
Mechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptases. J Biol Chem (2005) 1.10
The biased nucleotide composition of the HIV genome: a constant factor in a highly variable virus. Retrovirology (2012) 1.10
Influence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutant frequencies. J Virol (2003) 1.09
Current perspectives on HIV-1 antiretroviral drug resistance. Viruses (2014) 1.04
Precise identification of a human immunodeficiency virus type 1 antigen processing mutant. J Virol (2006) 1.02
Variation of HIV-1 mutation spectra among cell types. J Virol (2013) 0.90
Estimating the strength of selective sweeps from deep population diversity data. Genetics (2012) 0.90
The external domains of the HIV-1 envelope are a mutational cold spot. Nat Commun (2015) 0.89
Selection dramatically reduces effective population size in HIV-1 infection. BMC Evol Biol (2008) 0.89
5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors. Bioorg Med Chem (2013) 0.85
The high cost of fidelity. AIDS Res Hum Retroviruses (2014) 0.83
HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation. Retrovirology (2015) 0.83
Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation. PLoS Pathog (2016) 0.80
Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication. J Virol (2014) 0.78
Histidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins. J Virol (2016) 0.76
Retroviral vectors for analysis of viral mutagenesis and recombination. Viruses (2014) 0.76
Selection pressure in CD8⁺ T-cell epitopes in the pol gene of HIV-1 infected individuals in Colombia. A bioinformatic approach. Viruses (2015) 0.75
In vivo mutation rates and the landscape of fitness costs of HIV-1. Virus Evol (2017) 0.75
Evaluation of anti-HIV-1 mutagenic nucleoside analogues. J Biol Chem (2014) 0.75
Resolution of Specific Nucleotide Mismatches by Wild-Type and AZT-Resistant Reverse Transcriptases during HIV-1 Replication. J Mol Biol (2016) 0.75
Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra. J Mol Biol (2017) 0.75
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Global histone modification patterns predict risk of prostate cancer recurrence. Nature (2005) 7.03
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell (2011) 5.63
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. J Biol Chem (2007) 4.79
GeneWays: a system for extracting, analyzing, visualizing, and integrating molecular pathway data. J Biomed Inform (2004) 4.57
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc Natl Acad Sci U S A (2007) 4.20
Frontiers of biomedical text mining: current progress. Brief Bioinform (2007) 4.11
Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Mol Cell Biol (2002) 3.14
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol (2002) 2.95
Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (2009) 2.76
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Proc Natl Acad Sci U S A (2009) 2.57
Human immunodeficiency virus type 1 recombination: rate, fidelity, and putative hot spots. J Virol (2002) 2.50
Prognostic relevance of the mTOR pathway in renal cell carcinoma: implications for molecular patient selection for targeted therapy. Cancer (2007) 2.38
Global levels of histone modifications predict prognosis in different cancers. Am J Pathol (2009) 2.28
Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism. Proc Natl Acad Sci U S A (2002) 2.00
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading. Proc Natl Acad Sci U S A (2002) 1.95
Mutator phenotypes caused by substitution at a conserved motif A residue in eukaryotic DNA polymerase delta. J Biol Chem (2005) 1.94
Mouse model for human arginase deficiency. Mol Cell Biol (2002) 1.88
Mitochondrial 12S rRNA variants in 1642 Han Chinese pediatric subjects with aminoglycoside-induced and nonsyndromic hearing loss. Mitochondrion (2010) 1.80
A newly discovered function for RNase L in regulating translation termination. Nat Struct Mol Biol (2005) 1.80
Mutation at the polymerase active site of mouse DNA polymerase delta increases genomic instability and accelerates tumorigenesis. Mol Cell Biol (2007) 1.74
Automatically classifying sentences in full-text biomedical articles into Introduction, Methods, Results and Discussion. Bioinformatics (2009) 1.74
Down-regulation of miR-141 in gastric cancer and its involvement in cell growth. J Gastroenterol (2009) 1.73
Arginases I and II: do their functions overlap? Mol Genet Metab (2004) 1.67
Short communication: activation of latent HIV type 1 gene expression by suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor approved for use to treat cutaneous T cell lymphoma. AIDS Res Hum Retroviruses (2009) 1.66
New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. J Neurosci (2007) 1.62
Hypoxia-inducible factor 1 alpha in clear cell renal cell carcinoma. Clin Cancer Res (2007) 1.61
Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma. J Urol (2005) 1.60
Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol (2003) 1.57
AskHERMES: An online question answering system for complex clinical questions. J Biomed Inform (2011) 1.57
Regulation of mitochondrial oxidative phosphorylation through cell signaling. Biochim Biophys Acta (2007) 1.51
Using protein expressions to predict survival in clear cell renal carcinoma. Clin Cancer Res (2004) 1.51
Alternative mechanisms by which mediator subunit MED1/TRAP220 regulates peroxisome proliferator-activated receptor gamma-stimulated adipogenesis and target gene expression. Mol Cell Biol (2007) 1.50
Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability. Mol Cell Biol (2005) 1.50
Lancet: a high precision medication event extraction system for clinical text. J Am Med Inform Assoc (2010) 1.49
Human dermal stem cells differentiate into functional epidermal melanocytes. J Cell Sci (2010) 1.48
Complete genome sequence of bacteriophage T5. Virology (2005) 1.48
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron (2010) 1.45
Effect of antisense VEGF cDNA transfection on the growth of chronic myeloid leukemia K562 cells in vitro and in nude mice. Leuk Res (2004) 1.45
Role of individual basal ganglia nuclei in force amplitude generation. J Neurophysiol (2007) 1.44
Neuromodulation of the cingulum for neuropathic pain after spinal cord injury. Case report. J Neurosurg (2007) 1.42
Heat stress-induced response of the proteomes of leaves from Salvia splendens Vista and King. Proteome Sci (2013) 1.41
Association of genetic polymorphisms in the fibrinogen and platelet glycoprotein genes with unstable angina in Chinese patients. Clin Cardiol (2004) 1.39
TARPs differentially decorate AMPA receptors to specify neuropharmacology. Trends Neurosci (2010) 1.39
FigSum: automatically generating structured text summaries for figures in biomedical literature. AMIA Annu Symp Proc (2009) 1.38
A role for the melanocortin 4 receptor in sexual function. Proc Natl Acad Sci U S A (2002) 1.38
Parameter uncertainty analysis of non-point source pollution from different land use types. Sci Total Environ (2009) 1.37
Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma. Cancer Res (2007) 1.37
Statin and stromal cell-derived factor-1 additively promote angiogenesis by enhancement of progenitor cells incorporation into new vessels. Stem Cells (2008) 1.34
Hierarchical modularity of nested bow-ties in metabolic networks. BMC Bioinformatics (2006) 1.33
Immunoproteomic discovery of novel T cell antigens from the obligate intracellular pathogen Chlamydia. J Immunol (2008) 1.32
TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro. Arthritis Res Ther (2012) 1.30
Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage. Hypertension (2011) 1.29
High frequency deep brain stimulation attenuates subthalamic and cortical rhythms in Parkinson's disease. Front Hum Neurosci (2012) 1.29
Exploring supervised and unsupervised methods to detect topics in biomedical text. BMC Bioinformatics (2006) 1.28
Biomedical negation scope detection with conditional random fields. J Am Med Inform Assoc (2010) 1.27
Age-related molecular genetic changes of murine bone marrow mesenchymal stem cells. BMC Genomics (2010) 1.27
The human immunodeficiency virus type 1 ribosomal frameshifting site is an invariant sequence determinant and an important target for antiviral therapy. J Virol (2004) 1.27
Region of interest template for the human basal ganglia: comparing EPI and standardized space approaches. Neuroimage (2007) 1.26
Migration of mesenchymal stem cells to heart allografts during chronic rejection. Transplantation (2003) 1.26
Efficacy of pulmonary vein isolation by cryoballoon ablation in patients with paroxysmal atrial fibrillation. Heart Rhythm (2008) 1.26
Lethal mutagenesis of HIV. Virus Res (2005) 1.26
Modular co-evolution of metabolic networks. BMC Bioinformatics (2007) 1.23
Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence. Clin Cancer Res (2007) 1.23
Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII. Cancer Biol Ther (2006) 1.20
Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression. Genomics (2002) 1.20
Clinical study of laparoscopic versus open hepatectomy for malignant liver tumors. Surg Endosc (2008) 1.20
Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines. Hum Mol Genet (2002) 1.19
C-Myc-activated long noncoding RNA CCAT1 promotes colon cancer cell proliferation and invasion. Tumour Biol (2014) 1.19
The serine/threonine kinase dPak is required for polarized assembly of F-actin bundles and apical-basal polarity in the Drosophila follicular epithelium. Dev Biol (2007) 1.18
Interactions between extracellular signal-regulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity. J Bone Miner Res (2012) 1.18
Incorporation of uracil into minus strand DNA affects the specificity of plus strand synthesis initiation during lentiviral reverse transcription. J Biol Chem (2002) 1.16
Stromal cell-derived factor-1 enhances pro-angiogenic effect of granulocyte-colony stimulating factor. Cardiovasc Res (2006) 1.15
Laparoscopic liver resection and the learning curve: a 14-year, single-center experience. Surg Endosc (2014) 1.15
A pathway-dependent on apoE, ApoAI, and ABCA1 determines formation of buoyant high-density lipoprotein by macrophage foam cells. Arterioscler Thromb Vasc Biol (2007) 1.15
Role of the basal ganglia and frontal cortex in selecting and producing internally guided force pulses. Neuroimage (2007) 1.14
Availability and quality of paraffin blocks identified in pathology archives: a multi-institutional study by the Shared Pathology Informatics Network (SPIN). BMC Cancer (2007) 1.14
Effect of hepatocyte apoptosis induced by TNF-alpha on acute severe hepatitis in mouse models. World J Gastroenterol (2000) 1.14
Mutations in POFUT1, encoding protein O-fucosyltransferase 1, cause generalized Dowling-Degos disease. Am J Hum Genet (2013) 1.13
Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity. Cell Metab (2010) 1.13
Association study of the polymorphisms in the KISS1 gene with central precocious puberty in Chinese girls. Eur J Endocrinol (2007) 1.13
Small-molecule activation of the TRAIL receptor DR5 in human cancer cells. Nat Chem Biol (2012) 1.13
Decoding cell lineage from acquired mutations using arbitrary deep sequencing. Nat Methods (2011) 1.12
Carbonic anhydrase IX in bladder cancer: a diagnostic, prognostic, and therapeutic molecular marker. Cancer (2009) 1.11
Generation of mouse ES cell lines engineered for the forced induction of transcription factors. Sci Rep (2011) 1.11
Laparoscopic hepatectomy for hepatolithiasis: a feasibility and safety study in 29 patients. Surg Endosc (2007) 1.11
Genome-wide binding analysis of the transcription activator ideal plant architecture1 reveals a complex network regulating rice plant architecture. Plant Cell (2013) 1.10
Hydrogen peroxide-mediated isoniazid activation catalyzed by Mycobacterium tuberculosis catalase-peroxidase (KatG) and its S315T mutant. Biochemistry (2006) 1.10
Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction. Brain (2003) 1.10
Principles and analytical performance of Abbott RealTime High Risk HPV test. J Clin Virol (2009) 1.10
Intracranial hypotension producing reversible coma: a systematic review, including three new cases. J Neurosurg (2012) 1.09
CordyMax Cs-4 improves glucose metabolism and increases insulin sensitivity in normal rats. J Altern Complement Med (2002) 1.09
Age-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virus. Virol J (2011) 1.09
Automatically classifying sentences in full-text biomedical articles into introduction, methods, results and discussion. Summit on Translat Bioinforma (2009) 1.08
Automatically extracting information needs from complex clinical questions. J Biomed Inform (2010) 1.08