Published in J Nutr on August 01, 2002
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc Natl Acad Sci U S A (2007) 5.57
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect (2006) 4.46
Epigenetic transgenerational actions of environmental factors in disease etiology. Trends Endocrinol Metab (2010) 2.86
Prospects for epigenetic epidemiology. Am J Epidemiol (2009) 2.00
Epigenetic reprogramming and imprinting in origins of disease. Rev Endocr Metab Disord (2007) 1.75
Cancer chemoprevention by dietary polyphenols: promising role for epigenetics. Biochem Pharmacol (2010) 1.63
The functional significance of microRNA-145 in prostate cancer. Br J Cancer (2010) 1.48
Environmental exposures and gene regulation in disease etiology. Environ Health Perspect (2007) 1.44
Epigenetic targets of bioactive dietary components for cancer prevention and therapy. Clin Epigenetics (2010) 1.33
A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. Bioessays (2014) 1.33
DNA methylation in endometrial cancer. Epigenetics (2010) 1.32
The role of early life genistein exposures in modifying breast cancer risk. Br J Cancer (2008) 1.31
Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components. Curr Med Chem (2010) 1.30
Epigenetic changes induced by curcumin and other natural compounds. Genes Nutr (2011) 1.28
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer (2009) 1.26
Sex is a potent modifier of the cardiovascular system. J Clin Invest (2003) 1.26
Up-regulation of microRNA-21 correlates with lower kidney cancer survival. PLoS One (2012) 1.26
Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer. Mol Cancer (2013) 1.17
Techniques used in studies of epigenome dysregulation due to aberrant DNA methylation: an emphasis on fetal-based adult diseases. Reprod Toxicol (2007) 1.13
Is soy consumption good or bad for the breast? J Nutr (2010) 1.08
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice. BMC Physiol (2008) 1.07
Epigenetic control of aging. Antioxid Redox Signal (2010) 1.02
Dietary factors and epigenetic regulation for prostate cancer prevention. Adv Nutr (2011) 1.00
Induction of regulatory T cells by green tea polyphenol EGCG. Immunol Lett (2011) 0.99
Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr Cancer (2009) 0.96
Genistein affects histone modifications on Dickkopf-related protein 1 (DKK1) gene in SW480 human colon cancer cell line. PLoS One (2012) 0.93
Targeting the epigenome with bioactive food components for cancer prevention. J Nutrigenet Nutrigenomics (2012) 0.91
DNA methylation and histone modifications of Wnt genes by genistein during colon cancer development. Carcinogenesis (2013) 0.91
Impact of soy isoflavones on the epigenome in cancer prevention. Nutrients (2014) 0.90
Epigenetic changes with dietary soy in cynomolgus monkeys. PLoS One (2011) 0.89
Epigenetics and its implications for ecotoxicology. Ecotoxicology (2011) 0.89
Hypomethylation of Alu elements in post-menopausal women with osteoporosis. PLoS One (2013) 0.88
Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study. Environ Health Perspect (2016) 0.86
Systematic evaluation of genome-wide methylated DNA enrichment using a CpG island array. BMC Genomics (2011) 0.86
Quantitative proteomics and transcriptomics addressing the estrogen receptor subtype-mediated effects in T47D breast cancer cells exposed to the phytoestrogen genistein. Mol Cell Proteomics (2010) 0.86
Environmental Epigenetics: Crossroad between Public Health, Lifestyle, and Cancer Prevention. Biomed Res Int (2015) 0.84
Epigenetic regulation by selected dietary phytochemicals in cancer chemoprevention. Cancer Lett (2014) 0.84
Cocoa Consumption Alters the Global DNA Methylation of Peripheral Leukocytes in Humans with Cardiovascular Disease Risk Factors: A Randomized Controlled Trial. PLoS One (2013) 0.84
Environmental epigenetics and phytoestrogen/phytochemical exposures. J Steroid Biochem Mol Biol (2012) 0.84
Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges. Semin Cancer Biol (2016) 0.83
DNA demethylation and invasive cancer: implications for therapeutics. Br J Pharmacol (2015) 0.83
The impact of nutrition on differential methylated regions of the genome. Adv Nutr (2011) 0.82
DNA-intercalators causing rapid re-expression of methylated and silenced genes in cancer cells. Oncotarget (2013) 0.82
Isoflavones, their Glycosides and Glycoconjugates. Synthesis and Biological Activity. Curr Org Chem (2017) 0.81
DNA Methylation and Flavonoids in Genitourinary Cancers. Curr Pharmacol Rep (2015) 0.80
Stimulation of the immune response in B6C3F1 mice by genistein is affected by exposure duration, gender, and litter order. J Nutr (2005) 0.77
Genistein enhancement of respiratory allergen trimellitic anhydride-induced IgE production by adult B6C3F1 mice following in utero and postnatal exposure. Toxicol Sci (2005) 0.77
Genistein potentiates the effect of 17-beta estradiol on human hepatocellular carcinoma cell line. Adv Biomed Res (2016) 0.76
Speciation, phenotypic variation and plasticity: what can endocrine disruptors tell us? Int J Endocrinol (2013) 0.75
Embryonic environment and transgenerational effects in quail. Genet Sel Evol (2017) 0.75
Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques. Cancer Prev Res (Phila) (2016) 0.75
Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev (2002) 6.74
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet (2008) 5.08
Methylation-specific oligonucleotide microarray: a new potential for high-throughput methylation analysis. Genome Res (2002) 2.71
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J (2003) 2.21
Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. Hum Mol Genet (2003) 1.93
Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers. Clin Cancer Res (2002) 1.91
Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function. Cell Metab (2006) 1.84
The peroxisome proliferator-activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator-activated receptor-alpha-dependent manner in vitro and in vivo in mice. J Am Coll Cardiol (2008) 1.81
Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer. Cancer Res (2010) 1.69
Estrogen receptor-alpha mediates estrogen protection from angiotensin II-induced hypertension in conscious female mice. Am J Physiol Heart Circ Physiol (2006) 1.59
A histidine-rich cluster mediates the ubiquitination and degradation of the human zinc transporter, hZIP4, and protects against zinc cytotoxicity. J Biol Chem (2007) 1.58
Methylation target array for rapid analysis of CpG island hypermethylation in multiple tissue genomes. Am J Pathol (2003) 1.51
Copper-regulated trafficking of the Menkes disease copper ATPase is associated with formation of a phosphorylated catalytic intermediate. J Biol Chem (2002) 1.48
Applications of CpG island microarrays for high-throughput analysis of DNA methylation. J Nutr (2002) 1.46
Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Proc Natl Acad Sci U S A (2004) 1.45
Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer. Cancer Res (2003) 1.45
The soy isoflavone genistein decreases adipose deposition in mice. Endocrinology (2003) 1.43
Microsurgical anatomy of the posterior spinal artery via a far-lateral transcondylar approach. J Neurosurg Spine (2009) 1.43
Estrogen receptor alpha mediates estrogen's immune protection in autoimmune disease. J Immunol (2003) 1.40
Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation. Cancer Res (2003) 1.38
Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits. J Neurosci Res (2005) 1.38
High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring. Nat Commun (2012) 1.35
Phenotyping of transgenic cloned piglets. Cloning Stem Cells (2002) 1.34
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. Cancer Res (2003) 1.32
Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics. Cancer Res (2007) 1.31
The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells. J Biol Chem (2004) 1.28
Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer. Prostate (2012) 1.28
Oligonucleotide-based microarray for DNA methylation analysis: principles and applications. J Cell Biochem (2003) 1.26
A novel role for copper in Ras/mitogen-activated protein kinase signaling. Mol Cell Biol (2012) 1.24
Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas. Neoplasia (2005) 1.24
Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter. Hum Mol Genet (2004) 1.23
Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters. J Biol Chem (2004) 1.20
Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stability. J Biol Chem (2010) 1.19
Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell. Endocrinology (2003) 1.17
Quantitative assessment of DNA methylation: Potential applications for disease diagnosis, classification, and prognosis in clinical settings. J Mol Med (Berl) (2006) 1.16
Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. Breast Cancer Res (2012) 1.14
Impact on bone of an estrogen receptor-alpha gene loss of function mutation. J Clin Endocrinol Metab (2008) 1.12
Anoikis effector Bit1 negatively regulates Erk activity. Proc Natl Acad Sci U S A (2008) 1.11
Epigenetic gene silencing in cancer initiation and progression. Cancer Lett (2003) 1.08
High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion. Circ Res (2006) 1.06
Promoter region methylation and reduced expression of thrombospondin-1 after oxygen-glucose deprivation in murine cerebral endothelial cells. J Cereb Blood Flow Metab (2006) 1.04
Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia (2007) 1.03
Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro. Nutr Cancer (2004) 1.03
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice. Carcinogenesis (2009) 1.02
Epigenetic hypothesis tests for methylation and acetylation in a triple microarray system. J Comput Biol (2005) 1.01
PRIMA-1 inhibits growth of breast cancer cells by re-activating mutant p53 protein. Int J Oncol (2009) 0.99
Expressed CpG island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells. Cancer Res (2002) 0.99
Promoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer. Clin Cancer Res (2013) 0.99
Estrogen receptor-alpha deficiency promotes increased TNF-alpha secretion and bacterial killing by murine macrophages in response to microbial stimuli in vitro. J Leukoc Biol (2004) 0.98
Estrogen receptor-alpha mediates estrogen facilitation of baroreflex heart rate responses in conscious mice. Am J Physiol Heart Circ Physiol (2004) 0.98
Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers. Epigenetics (2013) 0.96
Aggressive prostate cancer is prevented in ERαKO mice and stimulated in ERβKO TRAMP mice. Endocrinology (2012) 0.96
Estrogen receptor alpha-mediated events promote sex-specific diabetic glomerular hypertrophy. Am J Physiol Renal Physiol (2004) 0.96
Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women. Nutr Cancer (2009) 0.96
Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain. Proc Natl Acad Sci U S A (2013) 0.96
Near-infrared fluorescence imaging of gastrin releasing peptide receptor targeting in prostate cancer lymph node metastases. Prostate (2012) 0.95
Identification and characterization of two novel splicing isoforms of human estrogen-related receptor beta. J Clin Endocrinol Metab (2005) 0.95
Differential methylation hybridization using CpG island arrays. Methods Mol Biol (2002) 0.95
Bronchial varices in congenital unilateral pulmonary vein atresia. Am J Respir Crit Care Med (2013) 0.95
Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers. Clin Cancer Res (2007) 0.94
Soy isoflavones increase latency of spontaneous mammary tumors in mice. J Nutr (2002) 0.93
Genome-wide analysis of changes in early gene expression induced by oestrogen. Genes Cells (2002) 0.93
Phenotypic diversity of Menkes disease in mottled mice is associated with defects in localisation and trafficking of the ATP7A protein. J Med Genet (2007) 0.92
Synthetic progestins induce growth and metastasis of BT-474 human breast cancer xenografts in nude mice. Menopause (2010) 0.91
Ribosomal DNA methylation in patients with endometrial carcinoma: an independent prognostic marker. Cancer (2002) 0.90
Expression of aquaporins in the efferent ductules, sperm counts, and sperm motility in estrogen receptor-alpha deficient mice fed lab chow versus casein. Mol Reprod Dev (2006) 0.90
Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells. J Neuroinflammation (2013) 0.89
Apigenin induces apoptosis and blocks growth of medroxyprogesterone acetate-dependent BT-474 xenograft tumors. Horm Cancer (2012) 0.89
Dietary soy isoflavones and estrone protect ovariectomized ERalphaKO and wild-type mice from carcinogen-induced colon cancer. J Nutr (2004) 0.89
Proteomic quantification and site-mapping of S-nitrosylated proteins using isobaric iodoTMT reagents. J Proteome Res (2014) 0.89
An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer. BMC Med Genomics (2010) 0.88
Re-activation of the p53 pathway inhibits in vivo and in vitro growth of hormone-dependent human breast cancer cells. Int J Oncol (2007) 0.88
Estrogen receptor-alpha and -beta and aromatase knockout effects on lower limb muscle mass and contractile function in female mice. Am J Physiol Endocrinol Metab (2009) 0.88
Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells. Endocrine (2007) 0.87
ERRbeta: a potent inhibitor of Nrf2 transcriptional activity. Mol Cell Endocrinol (2007) 0.87
Estrogen receptor alpha is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in the aromatase transgenic mice. J Steroid Biochem Mol Biol (2005) 0.87
Estrogen modulation of baroreflex function in conscious mice. Am J Physiol Regul Integr Comp Physiol (2003) 0.87
The neuroprotective effects of apocynin. Front Biosci (Elite Ed) (2012) 0.87
Telomerase gene mutations and telomere length shortening in patients with idiopathic pulmonary fibrosis in a Chinese population. Respirology (2014) 0.86
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats. Clin Cancer Res (2006) 0.86
Integrated analysis identifies a class of androgen-responsive genes regulated by short combinatorial long-range mechanism facilitated by CTCF. Nucleic Acids Res (2012) 0.86
Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma. Genes Chromosomes Cancer (2009) 0.86
Curcumin delays development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors. Menopause (2010) 0.86
Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors. Breast Cancer Res Treat (2010) 0.86
Acupuncture point specificity. Int Rev Neurobiol (2013) 0.85
Epigenetic deregulation of the anaplastic lymphoma kinase gene modulates mesenchymal characteristics of oral squamous cell carcinomas. Carcinogenesis (2013) 0.84
Estrogenic regulation of host immunity against an estrogen receptor-negative human breast cancer. Clin Cancer Res (2006) 0.84
Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1. Stem Cells (2014) 0.84
The Xpc gene markedly affects cell survival in mouse bone marrow. Mutagenesis (2009) 0.84
Regulation of nitric oxide-dependent vasodilation in coronary arteries of estrogen receptor-alpha-deficient mice. Am J Physiol Heart Circ Physiol (2003) 0.83
Methylation-specific oligonucleotide microarray. Methods Mol Biol (2004) 0.83
Phytosterol Pygeum africanum regulates prostate cancer in vitro and in vivo. Endocrine (2007) 0.83