Published in Eur J Biochem on September 01, 2002
Crystal structure of a clip-domain serine protease and functional roles of the clip domains. EMBO J (2005) 1.58
Identification of plasma proteases inhibited by Manduca sexta serpin-4 and serpin-5 and their association with components of the prophenol oxidase activation pathway. J Biol Chem (2005) 1.25
Manduca sexta prophenoloxidase (proPO) activation requires proPO-activating proteinase (PAP) and serine proteinase homologs (SPHs) simultaneously. Insect Biochem Mol Biol (2005) 1.13
The mosquito melanization response is implicated in defense against the entomopathogenic fungus Beauveria bassiana. PLoS Pathog (2012) 1.11
Diversity of innate immune recognition mechanism for bacterial polymeric meso-diaminopimelic acid-type peptidoglycan in insects. J Biol Chem (2010) 0.93
Identification of immunity-related genes in Ostrinia furnacalis against entomopathogenic fungi by RNA-seq analysis. PLoS One (2014) 0.87
Serine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanogaster. PLoS One (2013) 0.84
Cathepsin B homologue at the interface between a parasitic nematode and its intermediate host. Infect Immun (2006) 0.84
Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila. Mol Biol Evol (2011) 0.80
Identification of a serine proteinase homolog (Sp-SPH) involved in immune defense in the mud crab Scylla paramamosain. PLoS One (2013) 0.79
A serine protease homolog negatively regulates TEP1 consumption in systemic infections of the malaria vector Anopheles gambiae. J Innate Immun (2014) 0.79
High throughput profiling of the cotton bollworm Helicoverpa armigera immunotranscriptome during the fungal and bacterial infections. BMC Genomics (2015) 0.79
Selectively enhanced expression of prophenoloxidase activating enzyme 1 (PPAE1) at a bacteria clearance site in the white shrimp, Litopenaeus vannamei. BMC Immunol (2011) 0.78
Shrimp serine proteinase homologues PmMasSPH-1 and -2 play a role in the activation of the prophenoloxidase system. PLoS One (2015) 0.75
Bacillus subtillis RTSBA6 6.00, a new strain isolated from gut of Helicoverpa armigera (Lepidoptera: Noctuidae) produces chymotrypsin-like proteases. Saudi J Biol Sci (2012) 0.75
The Silencing of a 14-3-3ɛ Homolog in Tenebrio molitor Leads to Increased Antimicrobial Activity in Hemocyte and Reduces Larval Survivability. Genes (Basel) (2016) 0.75
Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial. Lancet Oncol (2010) 5.51
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Concern Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation (2002) 4.16
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Ice age terminations. Science (2009) 3.68
Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction. Biochem Biophys Res Commun (2009) 3.49
Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. Antimicrob Agents Chemother (2008) 3.10
The proPO-system: pros and cons for its role in invertebrate immunity. Trends Immunol (2008) 2.98
Effect of aging and physical activity on left ventricular compliance. Circulation (2004) 2.68
Performance of high-risk human papillomavirus DNA testing as a primary screen for cervical cancer: a pooled analysis of individual patient data from 17 population-based studies from China. Lancet Oncol (2010) 2.61
Persistent sympathetic activation during chronic antihypertensive therapy: a potential mechanism for long term morbidity? Hypertension (2005) 2.48
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. Nat Genet (2011) 2.27
Mitofusin 2 inhibits mitochondrial antiviral signaling. Sci Signal (2009) 2.25
Recent advances in the innate immunity of invertebrate animals. J Biochem Mol Biol (2005) 1.94
Calmodulin kinase II inhibition shortens action potential duration by upregulation of K+ currents. Circ Res (2006) 1.94
Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo. Am J Physiol Heart Circ Physiol (2006) 1.86
PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. PLoS One (2009) 1.86
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet (2012) 1.85
Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy. Circulation (2006) 1.85
Plasmid-mediated carbapenem-hydrolysing beta-lactamase KPC-2 in carbapenem-resistant Serratia marcescens isolates from Hangzhou, China. J Antimicrob Chemother (2007) 1.84
A calcium sensor in the sodium channel modulates cardiac excitability. Nature (2002) 1.83
Cell-mediated immunity in arthropods: hematopoiesis, coagulation, melanization and opsonization. Immunobiology (2006) 1.81
Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science (2013) 1.76
Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer. Mol Cancer (2011) 1.75
Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells. Proc Natl Acad Sci U S A (2006) 1.74
Skin cooling maintains cerebral blood flow velocity and orthostatic tolerance during tilting in heated humans. J Appl Physiol (1985) (2002) 1.67
Heat stress reduces cerebral blood velocity and markedly impairs orthostatic tolerance in humans. Am J Physiol Regul Integr Comp Physiol (2006) 1.65
Hemodynamics of orthostatic intolerance: implications for gender differences. Am J Physiol Heart Circ Physiol (2003) 1.65
Calmodulin kinase II activity is required for normal atrioventricular nodal conduction. Heart Rhythm (2005) 1.63
Small-animal PET imaging of human epidermal growth factor receptor type 2 expression with site-specific 18F-labeled protein scaffold molecules. J Nucl Med (2008) 1.63
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. Cancer Biol Ther (2009) 1.61
Crystal structure of a clip-domain serine protease and functional roles of the clip domains. EMBO J (2005) 1.58
Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing. J Appl Physiol (1985) (2006) 1.57
AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation. J Biol Chem (2004) 1.56
Human muscle sympathetic neural and haemodynamic responses to tilt following spaceflight. J Physiol (2002) 1.56
Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart. J Clin Invest (2009) 1.56
Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility genes in the Chinese: significant linkage to chromosome 6q21-q23 and chromosome 1q21-q24. Diabetes (2004) 1.54
Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. Am J Physiol Heart Circ Physiol (2007) 1.54
Cerebral vasomotor reactivity before and after blood pressure reduction in hypertensive patients. Am J Hypertens (2009) 1.53
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am J Pathol (2007) 1.52
CT and MRI of radiation-induced sarcomas of the head and neck following radiotherapy for nasopharyngeal carcinoma. Clin Radiol (2013) 1.51
Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. Am J Pathol (2006) 1.50
MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. Cell Cycle (2012) 1.50
Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing. Nat Mater (2010) 1.50
Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling. Sci Signal (2011) 1.50
Increases in cerebrovascular impedance in older adults. J Appl Physiol (1985) (2011) 1.49
Early intrapulmonary recurrence after pulmonary metastasectomy related to colorectal cancer. Ann Thorac Surg (2010) 1.49
A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. Diabetes (2012) 1.47
Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J Biol Chem (2001) 1.47
Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis. J Clin Invest (2006) 1.46
Molecular control of phenoloxidase-induced melanin synthesis in an insect. J Biol Chem (2008) 1.42
The iron-binding protein Dps confers hydrogen peroxide stress resistance to Campylobacter jejuni. J Bacteriol (2003) 1.41
Proteolytic cascades and their involvement in invertebrate immunity. Trends Biochem Sci (2010) 1.40
Sequence analysis of the human fucosyltransferase 1 and 2 genes in Tibetan blood donors: identification of three novel alleles. Transfusion (2014) 1.40
Retracted The effects of dexamethasone on the proliferation and apoptosis of human ovarian cancer cells induced by paclitaxel. J Ovarian Res (2014) 1.40
Dynamic cerebral autoregulation during repeated squat-stand maneuvers. J Appl Physiol (1985) (2008) 1.39
Effects of active and passive smoking on the development of cardiovascular disease as assessed by a carotid intima-media thickness examination in patients with type 2 diabetes mellitus. Clin Exp Pharmacol Physiol (2015) 1.38
A three-step proteolytic cascade mediates the activation of the peptidoglycan-induced toll pathway in an insect. J Biol Chem (2008) 1.37
Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis. Mol Cell Biol (2002) 1.37
RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. J Biol Chem (2007) 1.37
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling. J Pathol (2011) 1.36
Homing of endogenous stem/progenitor cells for in situ tissue regeneration: Promises, strategies, and translational perspectives. Biomaterials (2011) 1.35
Endoscopic submucosal dissection as a treatment for gastric subepithelial tumors that originate from the muscularis propria layer: a preliminary analysis of appropriate indications. Surg Endosc (2013) 1.34
Web-based tailored education program for disease-free cancer survivors with cancer-related fatigue: a randomized controlled trial. J Clin Oncol (2012) 1.34
Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion. PLoS One (2010) 1.33
Reduced susceptibility to carbapenems in Klebsiella pneumoniae clinical isolates associated with plasmid-mediated beta-lactamase production and OmpK36 porin deficiency. J Med Microbiol (2009) 1.33
Phenoloxidase is an important component of the defense against Aeromonas hydrophila Infection in a crustacean, Pacifastacus leniusculus. J Biol Chem (2007) 1.31
Crystal structure of CCM3, a cerebral cavernous malformation protein critical for vascular integrity. J Biol Chem (2010) 1.30
Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complement. J Biol Chem (2004) 1.29
SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation. J Biol Chem (2006) 1.29
Genome-wide association study identifies three novel loci for type 2 diabetes. Hum Mol Genet (2013) 1.28
Preoperative plasma hyperfibrinogenemia is predictive of poor prognosis in patients with nonmetastatic colon cancer. Ann Surg Oncol (2013) 1.28
A new easter-type serine protease cleaves a masquerade-like protein during prophenoloxidase activation in Holotrichia diomphalia larvae. J Biol Chem (2002) 1.26
Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis. Int J Radiat Oncol Biol Phys (2009) 1.25
Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese. PLoS One (2010) 1.23
Urinary bladder smooth muscle engineered from adipose stem cells and a three dimensional synthetic composite. Biomaterials (2009) 1.21
The structural basis of integrin-linked kinase-PINCH interactions. Proc Natl Acad Sci U S A (2008) 1.21
The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. J Biol Chem (2009) 1.21
Extranodal follicular dendritic cell sarcoma of the pharyngeal region: a potential diagnostic pitfall, with literature review. Am J Clin Pathol (2010) 1.20
Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation. Mol Cell (2013) 1.17
Two-dimensional universal conductance fluctuations and the electron-phonon interaction of surface states in Bi2Te2Se microflakes. Sci Rep (2012) 1.17
Processed lipoaspirate cells for tissue engineering of the lower urinary tract: implications for the treatment of stress urinary incontinence and bladder reconstruction. J Urol (2005) 1.16
Regulatory polymorphisms in the promoter of CXCL10 gene and disease progression in male hepatitis B virus carriers. Gastroenterology (2008) 1.16
Highly sensitive glucose sensor based on pt nanoparticle/polyaniline hydrogel heterostructures. ACS Nano (2013) 1.15
Cyclin G2 dysregulation in human oral cancer. Cancer Res (2004) 1.15
Lipoproteins in bacteria: structures and biosynthetic pathways. FEBS J (2012) 1.14
Pathologic nodal classification is the most discriminating prognostic factor for disease-free survival in rectal cancer patients treated with preoperative chemoradiotherapy and curative resection. Int J Radiat Oncol Biol Phys (2009) 1.13
Cerebral hemodynamics during orthostatic stress assessed by nonlinear modeling. J Appl Physiol (1985) (2006) 1.12
Genome-wide association study identified a narrow chromosome 1 region associated with chicken growth traits. PLoS One (2012) 1.11
A novel method for direct site-specific radiolabeling of peptides using [18F]FDG. Bioconjug Chem (2009) 1.11
New objective measures to quantify stress urinary incontinence in a novel durable animal model of intrinsic sphincter deficiency. Am J Physiol Regul Integr Comp Physiol (2005) 1.11
Stress vulnerability during adolescent development in rats. Endocrinology (2010) 1.11
Molecular typing of CTX-M-producing escherichia coli isolates from environmental water, swine feces, specimens from healthy humans, and human patients. Appl Environ Microbiol (2013) 1.10
Altered cerebral hemodynamics in early Alzheimer disease: a pilot study using transcranial Doppler. J Alzheimers Dis (2009) 1.10
Cerebral autoregulation of blood velocity and volumetric flow during steady-state changes in arterial pressure. Hypertension (2013) 1.10
64Cu-labeled affibody molecules for imaging of HER2 expressing tumors. Mol Imaging Biol (2009) 1.10