Robert Brasseur

Author PubWeight™ 79.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Apolipoprotein L-I is the trypanosome lytic factor of human serum. Nature 2003 4.33
2 Edgetic perturbation models of human inherited disorders. Mol Syst Biol 2009 3.96
3 Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science 2005 3.06
4 'Edgetic' perturbation of a C. elegans BCL2 ortholog. Nat Methods 2009 1.74
5 Revisiting the Ramachandran plot: hard-sphere repulsion, electrostatics, and H-bonding in the alpha-helix. Protein Sci 2003 1.73
6 A new potent secondary amphipathic cell-penetrating peptide for siRNA delivery into mammalian cells. Mol Ther 2008 1.58
7 Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein. Mol Cell Biol 2005 1.47
8 Protein-nucleic acid recognition: statistical analysis of atomic interactions and influence of DNA structure. Proteins 2005 1.46
9 Juxtamembrane protein segments that contribute to recruitment of cholesterol into domains. Biochemistry 2006 1.36
10 Analysis of accessible surface of residues in proteins. Protein Sci 2003 1.22
11 New basic membrane-destabilizing peptides for plasmid-based gene delivery in vitro and in vivo. Mol Ther 2002 1.22
12 The Ramachandran plots of glycine and pre-proline. BMC Struct Biol 2005 1.20
13 Atomic force microscopy of supported lipid bilayers. Nat Protoc 2008 1.19
14 Aromatic side-chain interactions in proteins. I. Main structural features. Proteins 2002 1.09
15 Prediction of peptide structure: how far are we? Proteins 2006 1.08
16 Functional analysis of the cell division protein FtsW of Escherichia coli. J Bacteriol 2004 1.06
17 Anti-hemostatic effects of a serpin from the saliva of the tick Ixodes ricinus. J Biol Chem 2006 1.05
18 Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation. Nucleic Acids Res 2003 1.04
19 In vitro characterization of the homogalacturonan-binding domain of the wall-associated kinase WAK1 using site-directed mutagenesis. Phytochemistry 2006 1.03
20 The N-terminal juxtamembranous domain of KCNQ1 is critical for channel surface expression: implications in the Romano-Ward LQT1 syndrome. Circ Res 2006 1.01
21 Cholesterol interaction with proteins that partition into membrane domains: an overview. Subcell Biochem 2010 0.97
22 Partial atomic charges of amino acids in proteins. Proteins 2004 0.97
23 TP0453, a concealed outer membrane protein of Treponema pallidum, enhances membrane permeability. J Bacteriol 2005 0.96
24 Membrane topology of the Escherichia coli AmpG permease required for recycling of cell wall anhydromuropeptides and AmpC beta-lactamase induction. Antimicrob Agents Chemother 2005 0.96
25 Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus. FEBS J 2009 0.96
26 Happy birthday cell penetrating peptides: already 20 years. Biochim Biophys Acta 2010 0.95
27 Determination of the topology of the hydrophobic segment of mammalian diacylglycerol kinase epsilon in a cell membrane and its relationship to predictions from modeling. J Mol Biol 2008 0.94
28 Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV. Biochemistry 2007 0.93
29 Interactions of ciprofloxacin with DPPC and DPPG: fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis. Biochim Biophys Acta 2008 0.93
30 The role of proline in the membrane re-entrant helix of caveolin-1. J Biol Chem 2010 0.91
31 Analysis of the C-terminal membrane anchor domains of hepatitis C virus glycoproteins E1 and E2: toward a topological model. J Virol 2002 0.91
32 Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity. FEBS Lett 2008 0.91
33 Aromatic side-chain interactions in proteins. II. Near- and far-sequence Phe-X pairs. Proteins 2002 0.90
34 Distantly related lipocalins share two conserved clusters of hydrophobic residues: use in homology modeling. BMC Struct Biol 2008 0.90
35 The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative? Biochim Biophys Acta 2011 0.89
36 Ir-LBP, an ixodes ricinus tick salivary LTB4-binding lipocalin, interferes with host neutrophil function. PLoS One 2008 0.88
37 Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin. Pharm Res 2003 0.88
38 Structural features conferring dual geranyl/farnesyl diphosphate synthase activity to an aphid prenyltransferase. Insect Biochem Mol Biol 2009 0.88
39 Membrane destabilization induced by beta-amyloid peptide 29-42: importance of the amino-terminus. Chem Phys Lipids 2002 0.87
40 Tilted properties of the 67-78 fragment of alpha-synuclein are responsible for membrane destabilization and neurotoxicity. Proteins 2007 0.87
41 Effects of surfactin on membrane models displaying lipid phase separation. Biochim Biophys Acta 2012 0.86
42 In silico predictions of 3D structures of linear and cyclic peptides with natural and non-proteinogenic residues. J Pept Sci 2011 0.86
43 Prolactin/growth hormone-derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis. Proc Natl Acad Sci U S A 2006 0.86
44 Insight into the cellular uptake mechanism of a secondary amphipathic cell-penetrating peptide for siRNA delivery. Biochemistry 2010 0.86
45 Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX. FEBS Lett 2009 0.85
46 Standardized evaluation of protein stability. Biochim Biophys Acta 2010 0.84
47 HIV-1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment. Characterization of gp41 mutants. Eur J Biochem 2004 0.83
48 Role of the lid hydrophobicity pattern in pancreatic lipase activity. J Biol Chem 2005 0.83
49 Aromatic side-chain interactions in proteins. Near- and far-sequence His-X pairs. Biochim Biophys Acta 2003 0.83
50 Interaction of the 106-126 prion peptide with lipid membranes and potential implication for neurotoxicity. Biochem Biophys Res Commun 2005 0.83
51 Mutational analysis of the TRE2 oncogene encoding an inactive RabGAP. Biotechnol Lett 2007 0.82
52 Ixodes ricinus tick lipocalins: identification, cloning, phylogenetic analysis and biochemical characterization. PLoS One 2008 0.82
53 Transferrin-binding protein B of Neisseria meningitidis: sequence-based identification of the transferrin-Binding site confirmed by site-directed mutagenesis. J Bacteriol 2004 0.82
54 Acylated and unacylated ghrelin binding to membranes and to ghrelin receptor: towards a better understanding of the underlying mechanisms. Biochim Biophys Acta 2010 0.82
55 Characterization of the interactions between fluoroquinolone antibiotics and lipids: a multitechnique approach. Biophys J 2008 0.81
56 Fusogenic Alzheimer's peptide fragment Abeta (29-42) in interaction with lipid bilayers: secondary structure, dynamics, and specific interaction with phosphatidyl ethanolamine polar heads as revealed by solid-state NMR. Protein Sci 2005 0.81
57 Tilted peptides: the history. Curr Protein Pept Sci 2006 0.80
58 Realistic modeling approaches of structure-function properties of CPPs in non-covalent complexes. Biochim Biophys Acta 2010 0.80
59 Large changes in the CRAC segment of gp41 of HIV do not destroy fusion activity if the segment interacts with cholesterol. Biochemistry 2008 0.80
60 Computational study of colipase interaction with lipid droplets and bile salt micelles. Proteins 2008 0.79
61 Multi-scale simulation of the simian immunodeficiency virus fusion peptide. J Phys Chem B 2012 0.79
62 SAHBNET, an accessible surface-based elastic network: an application to membrane protein. Int J Mol Sci 2013 0.78
63 Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo. Biochim Biophys Acta 2012 0.78
64 Determination of the minimal fusion peptide of bovine leukemia virus gp30. Biochem Biophys Res Commun 2007 0.78
65 Self-assembling peptide-based nanoparticles for siRNA delivery in primary cell lines. Small 2012 0.78
66 Mode of membrane interaction and fusogenic properties of a de novo transmembrane model peptide depend on the length of the hydrophobic core. J Biol Chem 2007 0.78
67 PepLook: an innovative in silico tool for determination of structure, polymorphism and stability of peptides. Adv Exp Med Biol 2009 0.78
68 Structural polymorphism of two CPP: an important parameter of activity. Biochim Biophys Acta 2008 0.78
69 Probing the interaction forces between hydrophobic peptides and supported lipid bilayers using AFM. J Mol Recognit 2007 0.77
70 Monolayer properties of uronic acid bicatenary derivatives at the air-water interface: effect of hydroxyl group stereochemistry evidenced by experimental and computational approaches. Phys Chem Chem Phys 2011 0.77
71 The minimal fusion peptide of simian immunodeficiency virus corresponds to the 11 first residues of gp32. J Pept Sci 2008 0.77
72 Insertion of X-ray structures of proteins in membranes. J Mol Graph Model 2003 0.77
73 The SIV tilted peptide induces cylindrical reverse micelles in supported lipid bilayers. Biochemistry 2006 0.77
74 Rational design of complementary peptides to the betaAmyloid 29-42 fusion peptide: an application of PepDesign. Biochim Biophys Acta 2005 0.76
75 Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment. Biochim Biophys Acta 2003 0.76
76 Domain formation and permeabilization induced by the saponin α-hederin and its aglycone hederagenin in a cholesterol-containing bilayer. Langmuir 2014 0.76
77 A new in-silico method for determination of helical transmembrane domains based on the PepLook scan: application to IL-2Rβ and IL-2Rγc receptor chains. BMC Struct Biol 2011 0.75
78 Fusogenic tilted peptides induce nanoscale holes in supported phosphatidylcholine bilayers. Langmuir 2005 0.75
79 Impacts of the carbonyl group location of ester bond on interfacial properties of sugar-based surfactants: experimental and computational evidences. J Phys Chem B 2009 0.75
80 Aromatic side-chain interactions in proteins: near- and far-sequence Tyr-X pairs. Proteins 2004 0.75
81 Determination of the minimal fusion peptide of HIV, SIV and BLV fusion glycoproteins. Adv Exp Med Biol 2009 0.75
82 Exploring the active site cavity of human pancreatic lipase. Biochem Biophys Res Commun 2008 0.75