Published in J Leukoc Biol on October 01, 2002
Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases. J Leukoc Biol (2009) 2.17
Adaptive immune responses mediated by natural killer cells. Immunol Rev (2010) 1.48
Human cytomegalovirus elicits fetal gammadelta T cell responses in utero. J Exp Med (2010) 1.39
Natural killer cells in liver disease. Hepatology (2013) 1.31
Recognition of tumors by the innate immune system and natural killer cells. Adv Immunol (2014) 1.27
CD8+ T cells promote inflammation and apoptosis in the liver after sepsis: role of Fas-FasL. Am J Pathol (2007) 1.15
Cell death and fibrogenesis. Semin Liver Dis (2010) 1.09
Natural killer and natural killer T cells in liver fibrosis. Biochim Biophys Acta (2012) 1.00
Application of tissue-specific NK and NKT cell activity for tumor immunotherapy. J Autoimmun (2009) 0.92
CD11c identifies a subset of murine liver natural killer cells that responds to adenoviral hepatitis. J Leukoc Biol (2008) 0.91
Natural killer cell receptors and their ligands in liver diseases. Med Mol Morphol (2009) 0.88
The role of serpinb9/serine protease inhibitor 6 in preventing granzyme B-dependent hepatotoxicity. Hepatology (2007) 0.87
MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma. J Exp Clin Cancer Res (2014) 0.87
NKp30 is a functional activation receptor on a subset of rat natural killer cells. Eur J Immunol (2006) 0.86
Immunology of hepatocellular carcinoma. World J Hepatol (2015) 0.83
Receptor-interacting protein kinase 3 deficiency inhibits immune cell infiltration and attenuates organ injury in sepsis. Crit Care (2014) 0.81
NK cell development in bone marrow and liver: site matters. Genes Immun (2014) 0.80
The hepatic sinusoidal endothelial lining and colorectal liver metastases. World J Gastroenterol (2007) 0.80
Sorting Out Pandora's Box: Discerning the Dynamic Roles of Liver Microenvironment in Oncolytic Virus Therapy for Hepatocellular Carcinoma. Front Oncol (2014) 0.80
Impact of non-oncological factors on tumor recurrence after liver transplantation in hepatocellular carcinoma patients. World J Gastroenterol (2016) 0.77
Metabolic derivatives of alcohol and the molecular culprits of fibro-hepatocarcinogenesis: Allies or enemies? World J Gastroenterol (2016) 0.76
The Future Liver Remnant in Patients Undergoing the Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy (ALPPS) Maintains the Immunological Components of a Healthy Organ. Front Med (Lausanne) (2016) 0.75
STATs in NK-Cells: The Good, the Bad, and the Ugly. Front Immunol (2017) 0.75
Pit cells exclusively kill P815 tumor cells by the perforin/granzyme pathway. Comp Hepatol (2004) 0.75
Hepatic NK cell-mediated hypersensitivity to ConA-induced liver injury in mouse liver expressing hepatitis C virus polyprotein. Oncotarget (2016) 0.75
Selective Harvesting of Marginating-hepatic Leukocytes. J Vis Exp (2016) 0.75
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol (2010) 7.73
Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. Cell Stem Cell (2007) 7.05
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nat Med (2013) 4.22
The developing cancer stem-cell model: clinical challenges and opportunities. Lancet Oncol (2012) 2.83
Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp Hepatol (2002) 2.62
Colon cancer stem cells: promise of targeted therapy. Gastroenterology (2010) 2.58
Human and mouse granzyme A induce a proinflammatory cytokine response. Immunity (2008) 2.57
Apoptosis and non-apoptotic deaths in cancer development and treatment response. Cancer Treat Rev (2008) 2.20
Cancer stem cell niche: the place to be. Cancer Res (2011) 2.14
The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res (2010) 2.12
APRIL modulates B and T cell immunity. J Clin Invest (2002) 2.07
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients. Cell Stem Cell (2011) 1.80
Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging. Stem Cells (2015) 1.75
Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity. Cancer Res (2010) 1.71
Carbon nanomaterials in biosensors: should you use nanotubes or graphene? Angew Chem Int Ed Engl (2010) 1.70
Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development. Dev Dyn (2005) 1.60
Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer. Clin Cancer Res (2012) 1.60
The need for transparency and good practices in the qPCR literature. Nat Methods (2013) 1.58
Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. Stem Cells (2012) 1.55
Activation of the granzyme pathway in children with severe respiratory syncytial virus infection. Pediatr Res (2008) 1.54
Wnt3a binds to several sFRPs in the nanomolar range. Biochem Biophys Res Commun (2007) 1.52
The TNF family member APRIL dampens collagen-induced arthritis. Ann Rheum Dis (2012) 1.49
Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier. Am J Physiol Renal Physiol (2009) 1.48
Targeting Wnt signaling in colon cancer stem cells. Clin Cancer Res (2010) 1.46
The biochemiresistor: an ultrasensitive biosensor for small organic molecules. Angew Chem Int Ed Engl (2012) 1.41
Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation. Immunity (2002) 1.39
Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin. J Biol Chem (2005) 1.39
APRIL promotes B-1 cell-associated neoplasm. Cancer Cell (2004) 1.34
Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles. BMC Genomics (2005) 1.34
CD40 stimulation leads to effective therapy of CD40(-) tumors through induction of strong systemic cytotoxic T lymphocyte immunity. Proc Natl Acad Sci U S A (2002) 1.34
Molecular identification and targeting of colorectal cancer stem cells. Oncotarget (2010) 1.33
Underexpression of miR-34a in hepatocellular carcinoma and its contribution towards enhancement of proliferating inhibitory effects of agents targeting c-MET. PLoS One (2013) 1.33
IL-4-mediated drug resistance in colon cancer stem cells. Cell Cycle (2007) 1.29
Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells. PLoS One (2008) 1.26
Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events. J Biol Chem (2004) 1.23
Induced pluripotent stem cells in cardiovascular drug discovery. Circ Res (2013) 1.22
A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs. J Cell Sci (2007) 1.21
Contribution of high-resolution correlative imaging techniques in the study of the liver sieve in three-dimensions. Microsc Res Tech (2007) 1.21
The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation. Microbes Infect (2009) 1.19
Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin. J Med Chem (2007) 1.18
Granzymes at a glance. J Cell Sci (2006) 1.18
The new anti-actin agent dihydrohalichondramide reveals fenestrae-forming centers in hepatic endothelial cells. BMC Cell Biol (2002) 1.17
Pseudogenes as weaknesses of ACTB (Actb) and GAPDH (Gapdh) used as reference genes in reverse transcription and polymerase chain reactions. PLoS One (2012) 1.15
Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin. J Biol Chem (2002) 1.14
Mechanisms directing the nuclear localization of the CtBP family proteins. Mol Cell Biol (2006) 1.13
Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis. J Cell Biol (2003) 1.13
Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling. Dev Dyn (2007) 1.12
Betulinic acid, a natural compound with potent anticancer effects. Anticancer Drugs (2010) 1.11
Broad in vitro efficacy of plant-derived betulinic acid against cell lines derived from the most prevalent human cancer types. Cancer Lett (2006) 1.11
Cancer heterogeneity--a multifaceted view. EMBO Rep (2013) 1.11
APRIL but not BLyS serum levels are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival. Haematologica (2007) 1.11
Expression of decoy receptor 3 in liver tissue microarrays. Natl Med J India (2009) 1.09
Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion. Apoptosis (2009) 1.09
Tumor microvasculature supports proliferation and expansion of glioma-propagating cells. Int J Cancer (2009) 1.08
Ionic Liquid-assisted Synthesis of Polyaniline/Gold Nanocomposite and Its Biocatalytic Application. Nanoscale Res Lett (2008) 1.07
Detection and functional analysis of CD8+ T cells specific for PRAME: a target for T-cell therapy. Clin Cancer Res (2006) 1.06
Toward ubiquitous environmental gas sensors-capitalizing on the promise of graphene. Environ Sci Technol (2010) 1.06
Cancer stem cell dynamics in tumor progression and metastasis: is the microenvironment to blame? Cancer Lett (2012) 1.06
A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis. J Immunol (2004) 1.06
The proteoglycan (heparan sulfate proteoglycan) binding domain of APRIL serves as a platform for ligand multimerization and cross-linking. FASEB J (2009) 1.05
Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas. Blood (2011) 1.05
Significance of decoy receptor 3 in sera of hepatocellular carcinoma patients. Ups J Med Sci (2010) 1.04
Human perforin employs different avenues to damage membranes. J Biol Chem (2010) 1.03
Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells. J Biol Chem (2004) 1.02
A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death. J Cell Biol (2003) 1.02
Over-expression of decoy receptor 3 in gastric precancerous lesions and carcinoma. Ups J Med Sci (2008) 1.01
Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival. Blood (2011) 1.01
VEGF-induced mobilization of caveolae and increase in permeability of endothelial cells. Am J Physiol Cell Physiol (2002) 1.01
Effects of MACPF/CDC proteins on lipid membranes. Cell Mol Life Sci (2012) 1.00
NK cell protease granzyme M targets alpha-tubulin and disorganizes the microtubule network. J Immunol (2008) 1.00
Moving in the right direction-nanoimaging in cancer cell motility and metastasis. Microsc Res Tech (2007) 1.00
NF-kappaB protects from the lysosomal pathway of cell death. EMBO J (2003) 1.00
An optimized procedure for whole-mount in situ hybridization on mouse embryos and embryoid bodies. Nat Protoc (2008) 0.98
Actin filament formation, reorganization and migration are impaired in hepatic stellate cells under influence of trichostatin A, a histone deacetylase inhibitor. J Hepatol (2002) 0.98
TNFRSF6B neutralization antibody inhibits proliferation and induces apoptosis in hepatocellular carcinoma cell. Pathol Res Pract (2010) 0.98
Perforin rapidly induces plasma membrane phospholipid flip-flop. PLoS One (2011) 0.97
Fixation methods for electron microscopy of human and other liver. World J Gastroenterol (2010) 0.97
Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment. Genes Dev (2013) 0.96
Prognostic value of apoptosis in rectal cancer patients of the dutch total mesorectal excision trial: radiotherapy is redundant in intrinsically high-apoptotic tumors. Clin Cancer Res (2006) 0.96
The role of liver sinusoidal cells in hepatocyte-directed gene transfer. Am J Pathol (2009) 0.95
Granzyme A produced by γ(9)δ(2) T cells induces human macrophages to inhibit growth of an intracellular pathogen. PLoS Pathog (2013) 0.95
A quick, cost-free method of purification of DNA fragments from agarose gel. J Cancer (2012) 0.94
Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR-dependent manner. Eur J Immunol (2007) 0.94
A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells. J Biol Chem (2005) 0.93
Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure-activity relationship study based on inhibitors for the Wnt response. J Med Chem (2012) 0.93
Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma. Mol Oncol (2013) 0.92
Expression of the antiapoptotic protein BAG3 is a feature of pancreatic adenocarcinoma and its overexpression is associated with poorer survival. Am J Pathol (2012) 0.92
Tropoelastin massively associates during coacervation to form quantized protein spheres. Biochemistry (2006) 0.92
The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin. Exp Cell Res (2004) 0.92
Defects in tongue papillae and taste sensation indicate a problem with neurotrophic support in various neurological diseases. Neuroscientist (2008) 0.92
The selective growth inhibition of oral cancer by iron core-gold shell nanoparticles through mitochondria-mediated autophagy. Biomaterials (2011) 0.91
In situ polymerization of tropoelastin in the absence of chemical cross-linking. Biomaterials (2008) 0.90
SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity. Blood (2004) 0.90
Isolation and propagation of colon cancer stem cells. Methods Mol Biol (2013) 0.89
CyclinD1 protein plays different roles in modulating chemoresponses in MCF7 and MDA-MB231 cells. J Carcinog (2012) 0.89
Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism. Curr Opin Immunol (2003) 0.88
Interactions between rat colon carcinoma cells and Kupffer cells during the onset of hepatic metastasis. Int J Cancer (2004) 0.88
Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model. Blood (2013) 0.88