Published in Genet Epidemiol on October 01, 2002
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet (2004) 14.76
An evaluation of statistical approaches to rare variant analysis in genetic association studies. Genet Epidemiol (2010) 10.54
Simple and efficient analysis of disease association with missing genotype data. Am J Hum Genet (2008) 4.52
GERBIL: Genotype resolution and block identification using likelihood. Proc Natl Acad Sci U S A (2004) 4.36
Inference on haplotype effects in case-control studies using unphased genotype data. Am J Hum Genet (2003) 3.74
A fast method for computing high-significance disease association in large population-based studies. Am J Hum Genet (2006) 2.84
Ranks of genuine associations in whole-genome scans. Genetics (2005) 2.42
A powerful strategy to account for multiple testing in the context of haplotype analysis. Am J Hum Genet (2004) 2.07
Hierarchical modeling of linkage disequilibrium: genetic structure and spatial relations. Am J Hum Genet (2003) 2.05
Association mapping via regularized regression analysis of single-nucleotide-polymorphism haplotypes in variable-sized sliding windows. Am J Hum Genet (2007) 2.04
Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One (2007) 1.89
Generalized linear modeling with regularization for detecting common disease rare haplotype association. Genet Epidemiol (2009) 1.75
Haplotype and missing data inference in nuclear families. Genome Res (2004) 1.69
Identification of risk-related haplotypes with the use of multiple SNPs from nuclear families. Am J Hum Genet (2007) 1.59
Expansion of the human mu-opioid receptor gene architecture: novel functional variants. Hum Mol Genet (2008) 1.59
Comparisons of multi-marker association methods to detect association between a candidate region and disease. Genet Epidemiol (2010) 1.50
Genome-wide association studies: progress and potential for drug discovery and development. Nat Rev Drug Discov (2008) 1.45
Association of KCNB1 polymorphisms with lipid metabolisms and insulin resistance: a case-control design of population-based cross-sectional study in Chinese Han population. Lipids Health Dis (2015) 1.39
Gene, region and pathway level analyses in whole-genome studies. Genet Epidemiol (2010) 1.36
Simple methods for assessing haplotype-environment interactions in case-only and case-control studies. Genet Epidemiol (2007) 1.29
Performance of single nucleotide polymorphisms versus haplotypes for genome-wide association analysis in barley. PLoS One (2010) 1.11
Are molecular haplotypes worth the time and expense? A cost-effective method for applying molecular haplotypes. PLoS Genet (2006) 1.09
Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma. JAMA (2011) 1.06
An efficient method for multi-locus molecular haplotyping. Nucleic Acids Res (2006) 1.06
Association of a CYP4A11 variant and blood pressure in black men. J Am Soc Nephrol (2008) 1.04
A survey of haplotype variants at several disease candidate genes: the importance of rare variants for complex diseases. J Med Genet (2005) 1.02
Haplotype diversity in 11 candidate genes across four populations. Genetics (2005) 0.99
Host genetic factors and vaccine-induced immunity to HBV infection: haplotype analysis. PLoS One (2010) 0.95
PDA: Pooled DNA analyzer. BMC Bioinformatics (2006) 0.94
HLA haplotype and supertype associations with cellular immune responses and cytokine production in healthy children after rubella vaccine. Vaccine (2009) 0.94
Power of genetic association studies in the presence of linkage disequilibrium and allelic heterogeneity. Hum Hered (2008) 0.93
The heterogeneous allelic repertoire of human toll-like receptor (TLR) genes. PLoS One (2009) 0.93
Haplotype analysis improved evidence for candidate genes for intramuscular fat percentage from a genome wide association study of cattle. PLoS One (2011) 0.92
The effect of single-nucleotide polymorphism marker selection on patterns of haplotype blocks and haplotype frequency estimates. Am J Hum Genet (2005) 0.92
Genomics of the NF-κB signaling pathway: hypothesized role in ovarian cancer. Cancer Causes Control (2011) 0.91
Haplotype reconstruction in large pedigrees with untyped individuals through IBD inference. J Comput Biol (2011) 0.91
Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly. PLoS One (2011) 0.91
Detecting genome-wide haplotype polymorphism by combined use of Mendelian constraints and local population structure. Pac Symp Biocomput (2010) 0.90
Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer. Mol Carcinog (2011) 0.89
A Bayesian hierarchical model for detecting haplotype-haplotype and haplotype-environment interactions in genetic association studies. Hum Hered (2011) 0.89
Genetic variations in ADIPOQ gene are associated with chronic obstructive pulmonary disease. PLoS One (2012) 0.88
An analysis of genetic variation across the MBL2 locus in Dutch Caucasians indicates that 3' haplotypes could modify circulating levels of mannose-binding lectin. Hum Genet (2005) 0.88
Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population. J Lipid Res (2010) 0.88
Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power. Eur J Hum Genet (2009) 0.88
A genome-wide scan for breast cancer risk haplotypes among African American women. PLoS One (2013) 0.87
Association of genetic polymorphisms of eNOS with glaucoma. Mol Vis (2011) 0.87
A variable-sized sliding-window approach for genetic association studies via principal component analysis. Ann Hum Genet (2009) 0.86
A haplotype of the GOSR2 gene is associated with myocardial infarction in Japanese men. Genet Test Mol Biomarkers (2013) 0.86
Detecting associations of rare variants with common diseases: collapsing or haplotyping? Brief Bioinform (2015) 0.86
Haplotype reconstruction error as a classical misclassification problem: introducing sensitivity and specificity as error measures. PLoS One (2008) 0.84
Association tests based on the principal-component analysis. BMC Proc (2007) 0.84
SHARE: an adaptive algorithm to select the most informative set of SNPs for candidate genetic association. Biostatistics (2009) 0.83
Haplotype analysis of ApoAI gene and sepsis-associated acute lung injury. Lipids Health Dis (2014) 0.83
Robust testing of haplotype/disease association. BMC Genet (2005) 0.82
Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk. Eur J Cancer (2010) 0.82
Determination of haplotypes at structurally complex regions using emulsion haplotype fusion PCR. BMC Genomics (2012) 0.82
Modeling haplotype-haplotype interactions in case-control genetic association studies. Front Genet (2012) 0.82
Association of polymorphisms in survivin gene with the risk of hepatocellular carcinoma in Chinese han population: a case control study. BMC Med Genet (2012) 0.81
Association of rare haplotypes on ULK4 and MAP4 genes with hypertension. BMC Proc (2016) 0.81
Mapping Nucleotide Sequences that Encode Complex Binary Disease Traits with HapMap. Curr Genomics (2007) 0.81
Association between fibroblast growth factor 7 and the risk of chronic obstructive pulmonary disease. Acta Pharmacol Sin (2012) 0.81
Haplotype thinking in lung disease. Proc Am Thorac Soc (2007) 0.81
Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis. BMC Med Genet (2012) 0.80
Imputation without doing imputation: a new method for the detection of non-genotyped causal variants. Genet Epidemiol (2014) 0.79
Genome-wide association studies using haplotypes and individual SNPs in Simmental cattle. PLoS One (2014) 0.79
A statistical model for genetic mapping of viral infection by integrating epidemiological behavior. Stat Appl Genet Mol Biol (2009) 0.79
NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles. BMC Bioinformatics (2008) 0.78
The association of cholesterol absorption gene Numb polymorphism with Coronary Artery Disease among Han Chinese and Uighur Chinese in Xinjiang, China. Lipids Health Dis (2015) 0.78
Comparison of haplotype-based statistical tests for disease association with rare and common variants. Brief Bioinform (2015) 0.78
Modeling Informatively Missing Genotypes in Haplotype Analysis. Commun Stat Theory Methods (2009) 0.78
A hidden Markov model for haplotype inference for present-absent data of clustered genes using identified haplotypes and haplotype patterns. Front Genet (2014) 0.78
Risk haplotype analysis for bovine paratuberculosis. Mamm Genome (2009) 0.78
Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population. PLoS One (2015) 0.78
Multi-allelic haplotype model based on genetic partition for genomic prediction and variance component estimation using SNP markers. BMC Genet (2015) 0.78
PPARα gene polymorphisms modulate the association between physical activity and cardiometabolic risk. Nutr Metab Cardiovasc Dis (2014) 0.78
Comparison of linear mixed model analysis and genealogy-based haplotype clustering with a Bayesian approach for association mapping in a pedigreed population. BMC Proc (2012) 0.78
A graphical weighted power improving multiplicity correction approach for SNP selections. Curr Genomics (2014) 0.78
Meta-analysis of haplotype-association studies: comparison of methods and empirical evaluation of the literature. BMC Genet (2011) 0.77
Chromosome 9p21 and ABCA1 Genetic Variants and Their Interactions on Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population. Int J Mol Sci (2016) 0.77
Genetic variations in RORα are associated with chronic obstructive pulmonary disease. J Hum Genet (2014) 0.77
Osteoprotegerin CGA haplotype protection against cerebrovascular complications in anti-CCP negative patients with rheumatoid arthritis. PLoS One (2014) 0.77
A haplotype inference algorithm for trios based on deterministic sampling. BMC Genet (2010) 0.77
Unbiased and locally efficient estimation of genetic effect on quantitative trait in the presence of population admixture. Biometrics (2010) 0.77
Genome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer's disease in Caribbean Hispanic individuals. Oncotarget (2015) 0.76
Holm multiple correction for large-scale gene-shape association mapping. BMC Genet (2014) 0.76
Haplotype analysis of the XRCC1 gene and laryngeal cancer. Genet Test Mol Biomarkers (2014) 0.76
CGTS: a site-clustering graph based tagSNP selection algorithm in genotype data. BMC Bioinformatics (2009) 0.75
Polymorphisms in the Perilipin Gene May Affect Carcass Traits of Chinese Meat-type Chickens. Asian-Australas J Anim Sci (2015) 0.75
Association of C5aR1genetic polymorphisms with coronary artery disease in a Han population in Xinjiang, China. Diagn Pathol (2015) 0.75
More powerful haplotype sharing by accounting for the mode of inheritance. Genet Epidemiol (2009) 0.75
The Association of Mitofusion-2 Gene Polymorphisms with Susceptibility of Essential Hypertension in Northern Han Chinese Population. Int J Med Sci (2016) 0.75
Genome-wide Association Analysis Tracks Bacterial Leaf Blight Resistance Loci In Rice Diverse Germplasm. Rice (N Y) (2017) 0.75
Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. Oncotarget (2016) 0.75
Family-Based Multi-SNP X Chromosome Analysis Using Parent Information. Front Genet (2016) 0.75
Association mapping of resistance to rice blast in upland field conditions. Rice (N Y) (2016) 0.75
Association of nNOS gene polymorphism with ischemic stroke in Han Chinese of North China. ScientificWorldJournal (2013) 0.75
Relation between ADIPOQ gene polymorphisms and type 2 diabetes in a Chinese population. Int J Clin Exp Med (2015) 0.75
Association between polymorphisms in the flanking region of the TAFI gene and atherosclerotic cerebral infarction in a Chinese population. Lipids Health Dis (2014) 0.75
An EM algorithm based on an internal list for estimating haplotype distributions of rare variants from pooled genotype data. BMC Genet (2013) 0.75
Single Marker and Haplotype-Based Association Analysis of Semolina and Pasta Colour in Elite Durum Wheat Breeding Lines Using a High-Density Consensus Map. PLoS One (2017) 0.75
Accounting for linkage in family-based tests of association with missing parental genotypes. Am J Hum Genet (2003) 1.92
TAGster: efficient selection of LD tag SNPs in single or multiple populations. Bioinformatics (2007) 1.38
Tag SNP selection for candidate gene association studies using HapMap and gene resequencing data. Eur J Hum Genet (2007) 1.21
Testing for association with a case-parents design in the presence of genotyping errors. Genet Epidemiol (2004) 1.16
How well do HapMap haplotypes identify common haplotypes of genes? A comparison with haplotypes of 334 genes resequenced in the environmental genome project. Cancer Epidemiol Biomarkers Prev (2006) 0.96
Disease associations and family-based tests. Curr Protoc Hum Genet (2003) 0.75
Disease associations and family-based tests. Curr Protoc Hum Genet (2008) 0.75