Cre-loxP biochemistry.

Testing gene function early in the B cell lineage in mb1-cre mice. Proc Natl Acad Sci U S A (2006) 3.32

Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. J Neurosci (2006) 1.55

dSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae. Methods (2007) 1.28

Relevance of animal models to human eating disorders and obesity. Psychopharmacology (Berl) (2008) 1.13

FtsK translocation on DNA stops at XerCD-dif. Nucleic Acids Res (2009) 1.11

Specific expression of channelrhodopsin-2 in single neurons of Caenorhabditis elegans. PLoS One (2012) 1.04

Cre-lox-based method for generation of large deletions within the genomic magnetosome island of Magnetospirillum gryphiswaldense. Appl Environ Microbiol (2010) 0.99

A self-deleting Cre-lox-ermAM cassette, Cheshire, for marker-less gene deletion in Streptococcus pneumoniae. J Microbiol Methods (2009) 0.98

Requirements for catalysis in the Cre recombinase active site. Nucleic Acids Res (2010) 0.98

Real-time single-molecule tethered particle motion experiments reveal the kinetics and mechanisms of Cre-mediated site-specific recombination. Nucleic Acids Res (2012) 0.96

A simple and effective chromosome modification method for large-scale deletion of genome sequences and identification of essential genes in fission yeast. Nucleic Acids Res (2006) 0.95

Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase. PLoS One (2009) 0.89

Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11). Proc Natl Acad Sci U S A (2013) 0.88

Measurements of DNA-loop formation via Cre-mediated recombination. Nucleic Acids Res (2012) 0.86

Mesoporous silica nanoparticle-mediated intracellular cre protein delivery for maize genome editing via loxP site excision. Plant Physiol (2013) 0.83

Properties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy. Neoplasia (2005) 0.82

Real-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and λ Int. Nucleic Acids Res (2013) 0.80

Single molecule TPM analysis of the catalytic pentad mutants of Cre and Flp site-specific recombinases: contributions of the pentad residues to the pre-chemical steps of recombination. Nucleic Acids Res (2015) 0.79

Development of selectable marker free, insect resistant, transgenic mustard (Brassica juncea) plants using Cre/lox mediated recombination. BMC Biotechnol (2013) 0.78

Novel Heterotypic Rox Sites for Combinatorial Dre Recombination Strategies. G3 (Bethesda) (2015) 0.77

Monodispersity of recombinant Cre recombinase correlates with its effectiveness in vivo. BMC Biotechnol (2009) 0.75

Preferential synapsis of loxP sites drives ordered strand exchange in Cre-loxP site-specific recombination. Nat Chem Biol (2005) 1.77

The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure. Structure (2005) 1.64

Structure of the Y14-Magoh core of the exon junction complex. Curr Biol (2003) 1.43

Structural basis for specificity in the poxvirus topoisomerase. Mol Cell (2006) 1.34

Tetrameric structure of a serine integrase catalytic domain. Structure (2008) 1.21

Synapsis of loxP sites by Cre recombinase. J Biol Chem (2007) 1.14

Structural coupling between FKBP12 and buried water. Proteins (2009) 1.07

Solution conformations of prototype foamy virus integrase and its stable synaptic complex with U5 viral DNA. Structure (2012) 1.07

Role of pICLn in methylation of Sm proteins by PRMT5. J Biol Chem (2009) 1.07

Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J Biol Chem (2004) 1.06

Allosteric inhibition of human immunodeficiency virus integrase: late block during viral replication and abnormal multimerization involving specific protein domains. J Biol Chem (2014) 1.04

Disorder-to-order transition underlies the structural basis for the assembly of a transcriptionally active PGC-1α/ERRγ complex. Proc Natl Acad Sci U S A (2011) 1.01

Requirements for catalysis in the Cre recombinase active site. Nucleic Acids Res (2010) 0.98

Insights from the structure of a smallpox virus topoisomerase-DNA transition state mimic. Structure (2010) 0.98

Structural properties of HIV integrase. Lens epithelium-derived growth factor oligomers. J Biol Chem (2010) 0.98

Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res (2013) 0.97

Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2). J Biol Chem (2012) 0.94

Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes. Virology (2007) 0.88

Solution structure of the core SMN-Gemin2 complex. Biochem J (2012) 0.86

The survival motor neuron protein forms soluble glycine zipper oligomers. Structure (2012) 0.85

The group II intron ribonucleoprotein precursor is a large, loosely packed structure. Nucleic Acids Res (2010) 0.85

Quaternary arrangement of an active, native group II intron ribonucleoprotein complex revealed by small-angle X-ray scattering. Nucleic Acids Res (2014) 0.84

Cre Recombinase. Microbiol Spectr (2015) 0.82

Regulation of catalysis by the smallpox virus topoisomerase. J Biol Chem (2006) 0.82

Protein-nucleic acid complexes: large, small, old, and new. Curr Opin Struct Biol (2008) 0.77

Bending and cutting forks and flaps. Structure (2005) 0.76