Published in J Exp Med on August 01, 1975
On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? J Exp Med (1978) 9.51
The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help. J Exp Med (1978) 4.27
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J Exp Med (1978) 3.46
Virus and trinitrophenol hapten-specific T-cell-mediated cytotoxicity against H-2 incompatible target cells. J Exp Med (1976) 3.00
Humoral and cell-mediated immune responses in fully allogeneic bone marrow chimera in mice. J Exp Med (1980) 1.94
Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction. J Immunol (1997) 1.81
Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules. J Exp Med (1981) 1.65
Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy. J Exp Med (1990) 1.54
Reconstitution after transplantation with T-lymphocyte-depleted HLA haplotype-mismatched bone marrow for severe combined immunodeficiency. Proc Natl Acad Sci U S A (1982) 1.44
Recirculating, suppressor T cells in transplantation tolerance. J Exp Med (1977) 1.43
Mouse models of bone marrow transplantation. Biol Blood Marrow Transplant (2008) 1.35
Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants. J Exp Med (1976) 1.30
Human hematopoietic cells and thymic epithelial cells induce tolerance via different mechanisms in the SCID-hu mouse thymus. J Exp Med (1992) 1.07
Tolerance of CD8+ T cells developing in parent-->F1 chimeras prepared with supralethal irradiation: step-wise induction of tolerance in the intrathymic and extrathymic environments. J Exp Med (1993) 1.03
Self recognition by T cells. I. Bystander killing of target cells bearing syngeneic MHC antigens. J Exp Med (1989) 0.91
Physiology of B cells in mice with X-linked immunodeficiency. II. Influence of the thymus and mature T cells on B cell differentiation. J Exp Med (1984) 0.91
Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. V. F1 mice with secondary chronic GVHD contain F1-reactive allohelper but no allosuppressor T cells. J Exp Med (1984) 0.85
Presence of host-reactive T cells in lymphohaematopoietic chimeras. Immunology (1983) 0.81
Can studies of tolerance ever lead to therapy? Ann Rheum Dis (2006) 0.79
Cellular basis of graft versus host tolerance in chimeras prepared with total lymphoid irradiation. J Exp Med (1980) 0.78
Treatment of an autoimmune disease with "classical" T cell veto: a proposal. J Clin Immunol (1999) 0.75
Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs. Immunology (1968) 11.20
Cell-mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse. Eur J Immunol (1974) 4.87
Some further data on cytotoxic isoantibodies in the mouse. Ann N Y Acad Sci (1962) 4.59
Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse. J Exp Med (1972) 4.59
Suppressor T cells. J Immunol (1972) 3.92
Circulating T and B lymphocytes of the mouse. I. Migratory properties. Cell Immunol (1973) 3.53
Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory. J Exp Med (1971) 3.14
Cell mediated immunity: separation of cells involved in recognitive and destructive phases. Science (1973) 3.04
Immunogenetic and biological aspects of in vitro lymphocyte allotransformation (MLR) in the mouse. Transplant Rev (1973) 2.79
Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras. J Exp Med (1975) 2.29
A major role for the Ir-1 region of the mouse H-2 complex in the mixed leukocyte reaction. Transplant Proc (1973) 1.97
Cellular immunology and the pathogenesis of graft versus host reactions. Prog Allergy (1971) 1.89
Graft-versus-host reactions across different regions of the H-2 complex of the mouse. J Exp Med (1973) 1.87
Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells. Cell Immunol (1972) 1.68
Effect of recent antigen priming on adoptive immune responses. I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes. J Exp Med (1973) 1.58
Nature of the stimulating cell in the syngeneic and the allogeneic mixed lymphocyte reaction in mice. J Exp Med (1972) 1.12
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity (1998) 9.02
Turnover of naive- and memory-phenotype T cells. J Exp Med (1994) 8.07
A receptor for antibody on B lymphocytes. I. Method of detection and functional significance. J Exp Med (1972) 7.47
Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science (1996) 7.00
IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A (2001) 6.91
Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell (1990) 6.33
T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature (1994) 6.20
A monoclonal antibody discriminating between subsets of T and B cells. J Immunol (1981) 6.15
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity (1999) 6.10
Cell-mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse. Eur J Immunol (1974) 4.87
Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature (1985) 4.22
Cloned T-cell lines with specific cytolytic activity. Curr Top Microbiol Immunol (1978) 3.60
Circulating T and B lymphocytes of the mouse. I. Migratory properties. Cell Immunol (1973) 3.53
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J Exp Med (1978) 3.46
Antigen-induced selective recruitment of circulating lymphocytes. Cell Immunol (1971) 3.35
Quantitative features of a sandwich radioimmunolabeling technique for lymphocyte surface receptors. J Exp Med (1972) 3.28
Fine specificity of a continuously growing killer cell clone specific for H-Y antigen. Eur J Immunol (1979) 3.27
Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory. J Exp Med (1971) 3.14
Interaction between lymphocytes in immune responses. Cell Immunol (1971) 3.03
Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras. J Exp Med (1975) 3.03
T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. J Immunol (1987) 2.93
DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites. J Biol Chem (2000) 2.90
Genetic analysis with human--mouse somatic cell hybrids. Nature (1969) 2.82
Reentry of T cells to the adult thymus is restricted to activated T cells. J Exp Med (1991) 2.81
Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens. J Exp Med (1985) 2.79
Cell-to-cell interaction in the immune response. X. T-cell-dependent suppression in tolerant mice. J Exp Med (1974) 2.77
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science (1999) 2.70
A defect in central tolerance in NOD mice. Nat Immunol (2001) 2.59
Type I interferon-mediated stimulation of T cells by CpG DNA. J Exp Med (1998) 2.58
Homeostatic T cell proliferation: how far can T cells be activated to self-ligands? J Exp Med (2000) 2.55
Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras. J Exp Med (1975) 2.29
T cell stimulation in vivo by lipopolysaccharide (LPS). J Exp Med (1997) 2.29
Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences. J Exp Med (1986) 2.29
Activation of thymus cells by histocompatibility antigens. Nat New Biol (1971) 2.26
High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61. J Immunol (1985) 2.20
Restricted helper function of F1 leads to parent bone marrow chimeras controlled by K-end of H-2 complex. J Exp Med (1978) 2.17
Identity of cells that imprint H-2-restricted T-cell specificity in the thymus. Nature (1986) 2.11
Thymus-derived cells in mouse thoracic duct lymph. Nat New Biol (1971) 2.07
Specific binding of alloantigens to T cells activated in the mixed lymphocyte reaction. J Exp Med (1976) 2.04
Perforin-mediated target cell lysis by cytolytic T lymphocytes. Annu Rev Immunol (1990) 2.03
Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo. Immunol Rev (1978) 1.95
Circulating T and B lymphocytes of the mouse. II. Lifespan. Cell Immunol (1973) 1.94
Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature (1985) 1.90
In vitro secondary mixed leukocyte reaction (MLR). II. Interaction MLR determinants expressed by F1 cells. Eur J Immunol (1977) 1.90
Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium. Cell Immunol (1976) 1.89
T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J Exp Med (2000) 1.88
Receptor for antibody-antigen complexes used to separate T cells from B cells. Nat New Biol (1972) 1.87
A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion. Immunogenetics (1981) 1.83
Surface immunoglobulins on thymus and thymus-derived lymphoid cells. J Exp Med (1971) 1.79
Genetic analysis with man-mouse somatic cell hybrids. Linkage between human lactate dehydrogenase B and peptidase B genes. Nature (1970) 1.79
Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells. Cell Immunol (1972) 1.78
Negative selection in the thymus includes semimature T cells. J Exp Med (1997) 1.77
The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens. J Exp Med (1977) 1.75
Abnormal differentiation of thymocytes in mice treated with cyclosporin A. Nature (1988) 1.73
Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells. J Exp Med (1997) 1.70
Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells. Cell Immunol (1972) 1.68
The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14. Nature (1986) 1.61
Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen-presenting cells in vivo. J Exp Med (1992) 1.61
Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Immunol (1985) 1.61
Two subsets of epithelial cells in the thymic medulla. J Exp Med (1992) 1.59
Upregulation of surface markers on dying thymocytes. J Exp Med (1995) 1.59
Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements. J Exp Med (1980) 1.59
Effect of recent antigen priming on adoptive immune responses. I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes. J Exp Med (1973) 1.58
Capacity of unprimed CD4+ and CD8+ T cells expressing V beta 11 receptors to respond to I-E alloantigens in vivo. J Exp Med (1989) 1.58
Five types of lymphocytes (Ig-theta-, Ig-theta+weak, Ig-theta+strong, Ig+theta- and Ig+theta+) characterized by double immunofluorescence and electrophoretic mobility. Organ distribution in normal and nude mice. Eur J Immunol (1975) 1.54
Cytolytic T lymphocytes. Annu Rev Immunol (1983) 1.54
Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy. J Exp Med (1990) 1.54
Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences. J Immunol (1985) 1.51
Lifespan of gamma/delta T cells. J Exp Med (1998) 1.49
T cell function in bone marrow chimeras: absence of host-reactive T cells and cooperation of helper T cells across allogeneic barriers. Transplant Rev (1976) 1.49
Interaction of thymus lymphocytes with histoincompatible cells. 3. Immunological characteristics of recirculating lymphocytes derived from activated thymus cells. Cell Immunol (1972) 1.49
Induction of neonatal tolerance to Mlsa antigens by CD8+ T cells. Science (1990) 1.47
Cell-to-cell interaction in the immune response. VII. Requirement for differentiation of thymus-derived cells. J Exp Med (1971) 1.46
Granules of cytolytic T-lymphocytes contain two serine esterases. EMBO J (1986) 1.44
Specific binding of K- and I-region products of the H-2 complex to activated thymus-derived (T) cells belonging to different Ly subclasses. J Exp Med (1976) 1.42
DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen. J Exp Med (1998) 1.41
Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med (1987) 1.41
Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection. Mucosal Immunol (2012) 1.39
An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma. J Immunol (2001) 1.38
Antigen-induced selective recruitment of circulating lymphocytes. 1971. J Immunol (2006) 1.37
Transgenic HLA-DR alpha faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to E alpha in E alpha 0 mutant mice. Cell (1989) 1.37
Functions of purified L3T4+ and Lyt-2+ cells in vitro and in vivo. Immunol Rev (1986) 1.36
Demonstration by MLR test of a previously unsuspected intra-H-2 crossover in the B10.HTT strain: implications concerning location of MLR determinants in the Ir region. Transplant Proc (1973) 1.33
A novel class II MHC molecule with unusual tissue distribution. Nature (1991) 1.33
Fc-receptors, Ia-antigens, and immunoglobulin on normal and activated mouse T lymphocytes. J Exp Med (1975) 1.32
Radiosensitivity of T and B lymphocytes. I. Effect of irradiation on cell migration. Eur J Immunol (1974) 1.31
T-cell activation. Annu Rev Cell Biol (1986) 1.31
Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V beta 11+ T cells. J Exp Med (1992) 1.30
Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants. J Exp Med (1976) 1.30
Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells. Immunity (1997) 1.30
A role for Fas in negative selection of thymocytes in vivo. J Exp Med (1998) 1.30
In vitro secondary MLR. I. Kinetics of proliferation and specificity of in vitro primed responder cells. J Immunol (1977) 1.29
Thymus-derived cells as killer cells in cell-mediated immunity. Transplant Proc (1971) 1.29
Hybrids between rat lymphoma and mouse T cells with inducible cytolytic activity. Nature (1982) 1.28
B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes. J Immunol (1994) 1.28
A bipartite interpretation and tentative mapping of H-2-associated MLR determinants in the mouse. Transplant Proc (1973) 1.27