Published in Genet Epidemiol on January 01, 2003
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
A simple and improved correction for population stratification in case-control studies. Am J Hum Genet (2007) 4.29
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Discovering genetic ancestry using spectral graph theory. Genet Epidemiol (2010) 3.03
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Detecting association of rare variants by testing an optimally weighted combination of variants for quantitative traits in general families. Ann Hum Genet (2013) 0.78
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Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort. PLoS One (2017) 0.75
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
De novo mutations in histone-modifying genes in congenital heart disease. Nature (2013) 5.15
Transferability of tag SNPs in genetic association studies in multiple populations. Nat Genet (2006) 4.78
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet (2004) 4.51
Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development. Plant Cell (2007) 4.13
Association mapping, using a mixture model for complex traits. Genet Epidemiol (2002) 3.95
Comparison of statistical methods for classification of ovarian cancer using mass spectrometry data. Bioinformatics (2003) 3.78
Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas. Cancer Res (2004) 3.64
Serum protein markers for early detection of ovarian cancer. Proc Natl Acad Sci U S A (2005) 3.22
The landscape of recombination in African Americans. Nature (2011) 3.06
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice. Nat Cell Biol (2003) 3.05
Genome scan among Nigerians linking blood pressure to chromosomes 2, 3, and 19. Hypertension (2002) 2.89
BGI-RIS: an integrated information resource and comparative analysis workbench for rice genomics. Nucleic Acids Res (2004) 2.69
Genetic analysis of variation in transcription factor binding in yeast. Nature (2010) 2.69
A transcriptome atlas of rice cell types uncovers cellular, functional and developmental hierarchies. Nat Genet (2009) 2.53
Fine mapping of the association with obesity at the FTO locus in African-derived populations. Hum Mol Genet (2010) 2.48
Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biol Psychiatry (2011) 2.45
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet (2007) 2.35
A statistical method for identifying differential gene-gene co-expression patterns. Bioinformatics (2004) 2.23
HAPLORE: a program for haplotype reconstruction in general pedigrees without recombination. Bioinformatics (2004) 2.16
Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet (2006) 2.15
Information assessment on predicting protein-protein interactions. BMC Bioinformatics (2004) 2.14
Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol (2005) 2.09
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Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans. Am J Med Genet B Neuropsychiatr Genet (2003) 2.07
Pathway analysis using random forests classification and regression. Bioinformatics (2006) 2.01
Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet (2006) 1.98
Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci (2008) 1.96
A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science (2004) 1.95
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94
Bias detection and correction in RNA-Sequencing data. BMC Bioinformatics (2011) 1.93
Genome-wide association of anthropometric traits in African- and African-derived populations. Hum Mol Genet (2010) 1.90
Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity (2013) 1.88
A combined analysis of genomewide linkage scans for body mass index from the National Heart, Lung, and Blood Institute Family Blood Pressure Program. Am J Hum Genet (2002) 1.87
Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. Circulation (2005) 1.84
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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents. Hepatology (2011) 1.79
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet (2011) 1.77
Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry (2011) 1.76
A candidate gene study of obstructive sleep apnea in European Americans and African Americans. Am J Respir Crit Care Med (2010) 1.74
A microarray analysis of the rice transcriptome and its comparison to Arabidopsis. Genome Res (2005) 1.71
A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology (2010) 1.71
Genome-wide association studies: implications for multiethnic samples. Hum Mol Genet (2008) 1.69
Relay ring-closing metathesis (RRCM): a strategy for directing metal movement throughout olefin metathesis sequences. J Am Chem Soc (2004) 1.69
Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells. Circulation (2012) 1.69
Two-stage designs in case-control association analysis. Genetics (2006) 1.65
Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage. Proc Natl Acad Sci U S A (2010) 1.60
Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma. Am J Respir Crit Care Med (2015) 1.58
Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis. J Mol Biol (2004) 1.57
The meiosis-specific zip4 protein regulates crossover distribution by promoting synaptonemal complex formation together with zip2. Dev Cell (2006) 1.57
Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy. Blood (2010) 1.56
Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. Hum Mol Genet (2007) 1.55
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Analyzing cellular biochemistry in terms of molecular networks. Annu Rev Biochem (2004) 1.55
Improving power in contrasting linkage-disequilibrium patterns between cases and controls. Am J Hum Genet (2007) 1.55
Haplotype-association analysis. Adv Genet (2008) 1.55
The impacts of errors in individual genotyping and DNA pooling on association studies. Genet Epidemiol (2004) 1.52
PathMAPA: a tool for displaying gene expression and performing statistical tests on metabolic pathways at multiple levels for Arabidopsis. BMC Bioinformatics (2003) 1.52
Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis. Plant Cell (2002) 1.52
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress. J Biol Chem (2003) 1.50
Comparisons of multi-marker association methods to detect association between a candidate region and disease. Genet Epidemiol (2010) 1.50
Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50
Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest (2009) 1.49
FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs. BMC Med Genet (2008) 1.48
Interrogating local population structure for fine mapping in genome-wide association studies. Bioinformatics (2010) 1.48
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet (2011) 1.47
Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila. Proc Natl Acad Sci U S A (2003) 1.46
Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease. Hum Mol Genet (2002) 1.44
An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population. J Hypertens (2003) 1.44
Adjustment for local ancestry in genetic association analysis of admixed populations. Bioinformatics (2010) 1.44
A comparison of several methods for haplotype frequency estimation and haplotype reconstruction for tightly linked markers from general pedigrees. Genet Epidemiol (2006) 1.43
Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genet Epidemiol (2011) 1.43
Molecular architecture of the chick vestibular hair bundle. Nat Neurosci (2013) 1.43
Finding genetic contributions to sporadic disease: a recessive locus at 12q24 commonly contributes to patent ductus arteriosus. Proc Natl Acad Sci U S A (2002) 1.42
Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito. Evolution (2013) 1.42
Analysis of far-red light-regulated genome expression profiles of phytochrome A pathway mutants in Arabidopsis. Plant J (2002) 1.40
VitaPad: visualization tools for the analysis of pathway data. Bioinformatics (2004) 1.39
Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene. Mamm Genome (2004) 1.39
Genome-wide searching of rare genetic variants in WTCCC data. Hum Genet (2010) 1.39
Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am J Med Genet A (2008) 1.39
Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis (2011) 1.38
Detection of DNA copy number alterations using penalized least squares regression. Bioinformatics (2005) 1.38
Analysis of the mutational effects of the COP/DET/FUS loci on genome expression profiles reveals their overlapping yet not identical roles in regulating Arabidopsis seedling development. Development (2003) 1.38
Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. Am J Hum Genet (2011) 1.35
Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum (2006) 1.35
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
On the use of DNA pooling to estimate haplotype frequencies. Genet Epidemiol (2003) 1.33
Inferring protein-protein interactions through high-throughput interaction data from diverse organisms. Bioinformatics (2005) 1.33
A genome-wide association study on obesity and obesity-related traits. PLoS One (2011) 1.33
Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry (2013) 1.32
PSMIX: an R package for population structure inference via maximum likelihood method. BMC Bioinformatics (2006) 1.32
Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program. Hypertension (2005) 1.32
Study of Arabidopsis thaliana resistome in response to cucumber mosaic virus infection using whole genome microarray. Plant Mol Biol (2004) 1.32
Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans. RNA (2011) 1.31