PubRank

Andrew L Mellor

Author PubWeight™ 111.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest 2007 5.05
2 GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity 2005 4.53
3 Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase. J Clin Invest 2007 4.44
4 Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest 2004 4.27
5 Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 2002 4.02
6 Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses. Cancer Res 2007 3.44
7 Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice. Immunity 2010 3.35
8 Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes. Blood 2009 2.88
9 IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J Immunol 2009 2.83
10 Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J Immunol 2004 2.77
11 Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol 2012 2.37
12 Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific. J Reprod Immunol 2004 2.30
13 Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proc Natl Acad Sci U S A 2009 2.22
14 Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase. Proc Natl Acad Sci U S A 2008 2.18
15 A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation. Int Immunol 2005 2.18
16 A critical role for the programmed death ligand 1 in fetomaternal tolerance. J Exp Med 2005 2.13
17 Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med 2010 2.12
18 Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality. Blood 2007 2.12
19 Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection. Int J Cancer 2002 2.10
20 IDO and tolerance to tumors. Trends Mol Med 2004 2.03
21 An inherently bifunctional subset of Foxp3+ T helper cells is controlled by the transcription factor eos. Immunity 2013 1.98
22 Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection. J Infect Dis 2011 1.86
23 Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. Int Immunol 2002 1.69
24 The tumor-draining lymph node as an immune-privileged site. Immunol Rev 2006 1.57
25 Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division. Immunology 2002 1.57
26 T cell costimulation molecules CD80/86 inhibit osteoclast differentiation by inducing the IDO/tryptophan pathway. Sci Transl Med 2014 1.56
27 Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia. J Infect Dis 2005 1.41
28 Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A 2012 1.37
29 Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality. Blood 2009 1.35
30 Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege. Int Rev Immunol 2010 1.29
31 Physiologic control of IDO competence in splenic dendritic cells. J Immunol 2011 1.29
32 Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells. Eur J Immunol 2007 1.27
33 Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma. Lab Invest 2003 1.23
34 Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation. Proc Natl Acad Sci U S A 2008 1.22
35 Leishmania major attenuates host immunity by stimulating local indoleamine 2,3-dioxygenase expression. J Infect Dis 2011 1.18
36 Amino acid catabolism: a pivotal regulator of innate and adaptive immunity. Immunol Rev 2012 1.16
37 B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A 2010 1.15
38 Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses. J Immunol 2013 1.13
39 Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapy. Immunotherapy 2009 1.10
40 Engineering DNA nanoparticles as immunomodulatory reagents that activate regulatory T cells. J Immunol 2012 1.06
41 Highlights of 10 years of immunology in Nature Reviews Immunology. Nat Rev Immunol 2011 1.06
42 A high-affinity, tryptophan-selective amino acid transport system in human macrophages. J Leukoc Biol 2006 1.04
43 Role of CD28 in fatal autoimmune disorder in scurfy mice. Blood 2007 1.04
44 Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype. Blood 2010 1.03
45 Marginal zone CD169+ macrophages coordinate apoptotic cell-driven cellular recruitment and tolerance. Proc Natl Acad Sci U S A 2014 1.02
46 Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy. Blood 2012 1.02
47 Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury. Am J Physiol Renal Physiol 2008 0.97
48 Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1). Stem Cells Dev 2010 0.97
49 Dendritic cells have the option to express IDO-mediated suppression or not. Blood 2005 0.96
50 Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection. PLoS One 2013 0.94
51 CD4(+)CD25(+) regulatory T cells resist a novel form of CD28- and Fas-dependent p53-induced T cell apoptosis. J Immunol 2009 0.91
52 GCN2-dependent metabolic stress is essential for endotoxemic cytokine induction and pathology. Mol Cell Biol 2013 0.89
53 Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state. J Biol Chem 2010 0.89
54 Deficiency of indoleamine 2,3-dioxygenase enhances commensal-induced antibody responses and protects against Citrobacter rodentium-induced colitis. Infect Immun 2008 0.89
55 T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenase. Handb Exp Pharmacol 2009 0.87
56 Inhibition of indoleamine 2,3-dioxygenase enhances the T-cell response to influenza virus infection. J Gen Virol 2013 0.87
57 Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases. Front Immunol 2012 0.85
58 Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression. Hum Immunol 2009 0.85
59 B7h (ICOS-L) maintains tolerance at the fetomaternal interface. Am J Pathol 2013 0.84
60 IFN-gamma-indoleamine-2,3 dioxygenase acts as a major suppressive factor in 4-1BB-mediated immune suppression in vivo. J Leukoc Biol 2009 0.83
61 Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase. Cell Mol Biol Lett 2006 0.83
62 Enrichment of regulatory CD4(+)CD25(+) T cells by inhibition of phospholipase D signaling. Nat Methods 2006 0.81
63 Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment. PLoS One 2013 0.81
64 Macrophages and the regulation of self-reactive T cells. Curr Pharm Des 2003 0.81
65 Indoleamine 2,3-dioxygenase (IDO) activity during the primary immune response to influenza infection modifies the memory T cell response to influenza challenge. Viral Immunol 2014 0.80
66 Constitutively CD40-activated B cells regulate CD8 T cell inflammatory response by IL-10 induction. J Immunol 2013 0.79
67 Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria. Int J Parasitol 2008 0.79
68 Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA. Eur J Immunol 2014 0.79
69 Metabolic control of tumour progression and antitumour immunity. Curr Opin Oncol 2014 0.77
70 STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy? Expert Rev Clin Immunol 2014 0.76