Published in J Mol Biol on February 21, 2003
The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A (2003) 5.13
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc Natl Acad Sci U S A (2008) 2.30
Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J (2005) 1.92
Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J (2003) 1.84
The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. EMBO J (2005) 1.79
Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol (2004) 1.66
Diversity and reductive evolution of mitochondria among microbial eukaryotes. Philos Trans R Soc Lond B Biol Sci (2010) 1.58
Quality control of mitochondrial proteostasis. Cold Spring Harb Perspect Biol (2011) 1.55
Mutation of DNAJC19, a human homologue of yeast inner mitochondrial membrane co-chaperones, causes DCMA syndrome, a novel autosomal recessive Barth syndrome-like condition. J Med Genet (2005) 1.41
Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria. J Cell Biol (2006) 1.30
A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Plant Physiol (2004) 1.27
Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol Cell Biol (2003) 1.14
Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria. Mol Biol Cell (2013) 1.04
Mitochondrial protein import and human health and disease. Biochim Biophys Acta (2006) 1.04
Functional expression of eukaryotic membrane proteins in Lactococcus lactis. Protein Sci (2005) 1.03
Involvement of the mitochondrial protein translocator component tim50 in growth, cell proliferation and the modulation of respiration in Drosophila. Genetics (2007) 0.90
Mitochondria, cognitive impairment, and Alzheimer's disease. Int J Alzheimers Dis (2009) 0.89
Protein import into hydrogenosomes of Trichomonas vaginalis involves both N-terminal and internal targeting signals: a case study of thioredoxin reductases. Eukaryot Cell (2008) 0.88
Protein translocase of mitochondrial inner membrane in Trypanosoma brucei. J Biol Chem (2012) 0.85
The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly. Sci Rep (2016) 0.84
The Role of Cardiolipin in Cardiovascular Health. Biomed Res Int (2015) 0.82
A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria. Mol Biol Cell (2014) 0.81
Metabolic biology of 3-methylglutaconic acid-uria: a new perspective. J Inherit Metab Dis (2014) 0.81
Alzheimer's pathogenesis and its link to the mitochondrion. Oxid Med Cell Longev (2015) 0.79
Ancestral and derived protein import pathways in the mitochondrion of Reclinomonas americana. Mol Biol Evol (2010) 0.79
Betanodavirus B2 causes ATP depletion-induced cell death via mitochondrial targeting and complex II inhibition in vitro and in vivo. J Biol Chem (2010) 0.78
An inception report on the TOM complex of the Amoeba Acanthamoeba castellanii, a simple model protozoan in mitochondria studies. J Bioenerg Biomembr (2005) 0.77
Importing mitochondrial proteins: machineries and mechanisms. Cell (2009) 5.46
The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A (2003) 5.13
Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature (2003) 3.46
Dissecting membrane insertion of mitochondrial beta-barrel proteins. Cell (2008) 2.97
Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res (2006) 2.92
Mitochondrial protein import: from proteomics to functional mechanisms. Nat Rev Mol Cell Biol (2010) 2.87
Mitochondrial import and the twin-pore translocase. Nat Rev Mol Cell Biol (2004) 2.78
An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane. J Biol Chem (2003) 2.59
Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell (2011) 2.52
Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell (2005) 2.49
Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J (2004) 2.43
Multiple pathways for sorting mitochondrial precursor proteins. EMBO Rep (2008) 2.19
Isolation of yeast mitochondria. Methods Mol Biol (2006) 2.09
The protein import machinery of mitochondria. J Biol Chem (2004) 2.02
The mitochondrial morphology protein Mdm10 functions in assembly of the preprotein translocase of the outer membrane. Dev Cell (2004) 1.98
Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability. Cell (2009) 1.96
The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel. Cell (2002) 1.95
Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J (2005) 1.92
Protein insertion into the mitochondrial inner membrane by a twin-pore translocase. Science (2003) 1.89
Mechanisms of protein import into mitochondria. Curr Biol (2003) 1.76
Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell (2006) 1.75
A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria. J Cell Biol (2003) 1.71
Motor-free mitochondrial presequence translocase drives membrane integration of preproteins. Nat Cell Biol (2007) 1.64
Pam16 has an essential role in the mitochondrial protein import motor. Nat Struct Mol Biol (2004) 1.63
Mitochondrial cardiolipin involved in outer-membrane protein biogenesis: implications for Barth syndrome. Curr Biol (2009) 1.62
Role of MINOS in mitochondrial membrane architecture: cristae morphology and outer membrane interactions differentially depend on mitofilin domains. J Mol Biol (2012) 1.61
The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J (2007) 1.58
Biogenesis of the protein import channel Tom40 of the mitochondrial outer membrane: intermembrane space components are involved in an early stage of the assembly pathway. J Biol Chem (2004) 1.55
Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science (2006) 1.55
Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway. J Mol Biol (2006) 1.53
Regulation of mitochondrial protein import by cytosolic kinases. Cell (2011) 1.42
The essential mitochondrial protein Erv1 cooperates with Mia40 in biogenesis of intermembrane space proteins. J Mol Biol (2005) 1.40
Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability. J Biol Chem (2004) 1.37
Role of MINOS in mitochondrial membrane architecture and biogenesis. Trends Cell Biol (2012) 1.36
Sorting switch of mitochondrial presequence translocase involves coupling of motor module to respiratory chain. J Cell Biol (2007) 1.36
Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol (2005) 1.34
The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J Biol Chem (2004) 1.34
Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics (2007) 1.33
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol (2008) 1.32
A role for Tim21 in membrane-potential-dependent preprotein sorting in mitochondria. Curr Biol (2006) 1.32
Import of proteins into mitochondria. Methods Cell Biol (2007) 1.30
Mitochondrial protein import: precursor oxidation in a ternary complex with disulfide carrier and sulfhydryl oxidase. J Cell Biol (2008) 1.28
Biogenesis of the essential Tim9-Tim10 chaperone complex of mitochondria: site-specific recognition of cysteine residues by the intermembrane space receptor Mia40. J Biol Chem (2007) 1.27
Cooperation of translocase complexes in mitochondrial protein import. J Cell Biol (2007) 1.26
Mitochondrial protein sorting: differentiation of beta-barrel assembly by Tom7-mediated segregation of Mdm10. J Biol Chem (2006) 1.24
Mitochondrial protein import: from transport pathways to an integrated network. Trends Biochem Sci (2011) 1.23
The mitochondrial proteome: from inventory to function. Cell (2008) 1.23
Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins. J Cell Biol (2007) 1.22
Precursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space. Mol Biol Cell (2007) 1.22
Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J (2003) 1.21
Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex. Mol Cell Biol (2002) 1.19
Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol (2005) 1.16
Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem (2007) 1.15
Mitochondria use different mechanisms for transport of multispanning membrane proteins through the intermembrane space. Mol Cell Biol (2003) 1.14
Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane. Mol Cell (2011) 1.14
Protein translocase of the outer mitochondrial membrane: role of import receptors in the structural organization of the TOM complex. J Mol Biol (2002) 1.12
Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel. Mol Cell (2002) 1.11
Distinct forms of mitochondrial TOM-TIM supercomplexes define signal-dependent states of preprotein sorting. Mol Cell Biol (2010) 1.11
Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation. Cell (2013) 1.11
A dynamic machinery for import of mitochondrial precursor proteins. FEBS Lett (2007) 1.10
Phosphatidylethanolamine and cardiolipin differentially affect the stability of mitochondrial respiratory chain supercomplexes. J Mol Biol (2012) 1.10
Mitofilin complexes: conserved organizers of mitochondrial membrane architecture. Biol Chem (2012) 1.06
Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex. Mol Cell Biol (2003) 1.05
The MIA system for protein import into the mitochondrial intermembrane space. Biochim Biophys Acta (2007) 1.05
Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase. Mol Biol Cell (2008) 1.04
The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. J Cell Biol (2011) 1.03
Two modular forms of the mitochondrial sorting and assembly machinery are involved in biogenesis of alpha-helical outer membrane proteins. J Mol Biol (2009) 1.01
Mitochondrial biogenesis, switching the sorting pathway of the intermembrane space receptor Mia40. J Biol Chem (2008) 1.01
The Tim21 binding domain connects the preprotein translocases of both mitochondrial membranes. EMBO Rep (2006) 1.00
Preprotein translocase of the outer mitochondrial membrane: reconstituted Tom40 forms a characteristic TOM pore. J Mol Biol (2005) 1.00
Biogenesis of mitochondrial membrane proteins. Curr Opin Cell Biol (2009) 1.00
Mitochondrial protein turnover: role of the precursor intermediate peptidase Oct1 in protein stabilization. Mol Biol Cell (2011) 0.97
Mitochondrial morphology and protein import--a tight connection? Biochim Biophys Acta (2006) 0.97
Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane. Mol Biol Cell (2012) 0.96
Powering mitochondrial protein import. Nat Struct Biol (2002) 0.96
Cooperation of stop-transfer and conservative sorting mechanisms in mitochondrial protein transport. Curr Biol (2010) 0.94
How mitochondria import hydrophilic and hydrophobic proteins. Trends Cell Biol (2002) 0.92
Diverse mechanisms and machineries for import of mitochondrial proteins. Biol Chem (2007) 0.92
Import of precursor proteins into isolated yeast mitochondria. Methods Mol Biol (2006) 0.92
Biochemistry. Assembling the outer membrane. Science (2010) 0.91
Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol (2012) 0.91
Mechanisms of protein sorting in mitochondria. Cold Spring Harb Perspect Biol (2012) 0.91
Biogenesis of mitochondria: dual role of Tom7 in modulating assembly of the preprotein translocase of the outer membrane. J Mol Biol (2010) 0.90
Chaperoning through the mitochondrial intermembrane space. Mol Cell (2006) 0.90
Mitochondrial protein import machineries and lipids: a functional connection. Biochim Biophys Acta (2010) 0.90
The assembly pathway of the mitochondrial carrier translocase involves four preprotein translocases. Mol Cell Biol (2008) 0.89
Biogenesis of yeast mitochondrial cytochrome c: a unique relationship to the TOM machinery. J Mol Biol (2003) 0.89
Cell biology. Connecting organelles. Science (2009) 0.87
Structural basis for the function of Tim50 in the mitochondrial presequence translocase. J Mol Biol (2011) 0.87
Biogenesis of mitochondrial β-barrel proteins: the POTRA domain is involved in precursor release from the SAM complex. Mol Biol Cell (2011) 0.86
Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase. EMBO Rep (2008) 0.84
Assembly of the mitochondrial protein import channel: role of Tom5 in two-stage interaction of Tom40 with the SAM complex. Mol Biol Cell (2010) 0.84
Role of membrane contact sites in protein import into mitochondria. Protein Sci (2015) 0.84
Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import. Mol Biol Cell (2012) 0.83
Evolution of mitochondrial protein biogenesis. Biochim Biophys Acta (2009) 0.83
The mitochondrial machinery for import of precursor proteins. Methods Mol Biol (2007) 0.82
Mitochondrial F1Fo-ATP synthase: the small subunits e and g associate with monomeric complexes to trigger dimerization. J Mol Biol (2009) 0.81
Protein conducting nanopores. J Phys Condens Matter (2010) 0.81
The protein import and assembly machinery of the mitochondrial outer membrane. Biochim Biophys Acta (2004) 0.81
Mitochondrial inner membrane protease promotes assembly of presequence translocase by removing a carboxy-terminal targeting sequence. Nat Commun (2013) 0.81