Published in Comp Biochem Physiol C Toxicol Pharmacol on February 01, 2003
A computational model of the hypothalamic: pituitary: gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone. BMC Syst Biol (2011) 0.85
ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas)-a critical analysis. Response to Mylchreest et al., Comp Biochem Physiol C 134: 251-257, 2003. Comp Biochem Physiol C Toxicol Pharmacol (2004) 0.77
Affinity and matrix effects in measuring fish plasma vitellogenin using immunosorbent assays: considerations for aquatic toxicologists. ISRN Toxicol (2012) 0.75
Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Toxicol Sci (2008) 1.71
Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals. Int J Androl (2006) 1.57
Effects of the androgenic growth promoter 17-beta-trenbolone on fecundity and reproductive endocrinology of the fathead minnow. Environ Toxicol Chem (2003) 1.45
Pharmaceuticals and personal care products in the environment: what are the big questions? Environ Health Perspect (2012) 1.38
Assessment of the risk of solar ultraviolet radiation to amphibians. III. Prediction of impacts in selected northern midwestern wetlands. Environ Sci Technol (2002) 1.07
Screening and testing for endocrine disruption in fish-biomarkers as "signposts," not "traffic lights," in risk assessment. Environ Health Perspect (2006) 1.07
Interactions between chemical and climate stressors: a role for mechanistic toxicology in assessing climate change risks. Environ Toxicol Chem (2013) 1.07
Ecotoxicogenomics: linkages between exposure and effects in assessing risks of aquatic contaminants to fish. Reprod Toxicol (2005) 1.01
Cloning and in vitro expression and characterization of the androgen receptor and isolation of estrogen receptor alpha from the fathead Minnow (Pimephales promelas). Environ Sci Technol (2004) 0.97
Identification of metabolites of trenbolone acetate in androgenic runoff from a beef feedlot. Environ Health Perspect (2006) 0.96
Evaluation of the aromatase inhibitor fadrozole in a short-term reproduction assay with the fathead minnow (Pimephales promelas). Toxicol Sci (2002) 0.94
A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis. Environ Sci Technol (2007) 0.94
Effects of the feedlot contaminant 17alpha-trenbolone on reproductive endocrinology of the fathead minnow. Environ Sci Technol (2006) 0.94
Linkage of biochemical responses to population-level effects: a case study with vitellogenin in the fathead minnow (Pimephales promelas). Environ Toxicol Chem (2007) 0.93
Reproductive toxicity of vinclozolin in the fathead minnow: confirming an anti-androgenic mode of action. Environ Toxicol Chem (2008) 0.93
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook. Environ Health Perspect (2010) 0.93
Current perspectives on the use of alternative species in human health and ecological hazard assessments. Environ Health Perspect (2013) 0.92
Quantitative proteomic profiles of androgen receptor signaling in the liver of fathead minnows (Pimephales promelas). J Proteome Res (2009) 0.92
Molecular target sequence similarity as a basis for species extrapolation to assess the ecological risk of chemicals with known modes of action. Aquat Toxicol (2013) 0.89
Evaluation of androstenedione as an androgenic component of river water downstream of a pulp and paper mill effluent. Environ Toxicol Chem (2002) 0.89
Metamorphic inhibition of Xenopus laevis by sodium perchlorate: effects on development and thyroid histology. Environ Toxicol Chem (2005) 0.89
Application of frog embryo teratogenesis assay-Xenopus to ecological risk assessment. Environ Toxicol Chem (2005) 0.89
Relationship between brain and ovary aromatase activity and isoform-specific aromatase mRNA expression in the fathead minnow (Pimephales promelas). Aquat Toxicol (2005) 0.87
Gonadal histology and characteristic histopathology associated with endocrine disruption in the adult fathead minnow (Pimephales promelas). Environ Toxicol Pharmacol (2005) 0.87
Influence of ovarian stage on transcript profiles in fathead minnow (Pimephales promelas) ovary tissue. Aquat Toxicol (2010) 0.87
Hypoxia alters gene expression in the gonads of zebrafish (Danio rerio). Aquat Toxicol (2008) 0.87
Modeling impacts on populations: fathead minnow (Pimephales promelas) exposure to the endocrine disruptor 17beta-trenbolone as a case study. Ecotoxicol Environ Saf (2004) 0.87
Developmental toxicity of methoprene and several degradation products in Xenopus laevis. Aquat Toxicol (2003) 0.86
Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen. BMC Genomics (2009) 0.86
International scientists' priorities for research on pharmaceutical and personal care products in the environment. Integr Environ Assess Manag (2014) 0.86
Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow. Aquat Toxicol (2004) 0.85
Effects of a 3beta-hydroxysteroid dehydrogenase inhibitor, trilostane, on the fathead minnow reproductive axis. Toxicol Sci (2008) 0.85
Adverse outcome pathways and ecological risk assessment: bridging to population-level effects. Environ Toxicol Chem (2011) 0.85
A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species. Aquat Toxicol (2010) 0.85
Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor. Environ Health Perspect (2008) 0.85
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain. Aquat Toxicol (2007) 0.85
A computational model of the hypothalamic: pituitary: gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone. BMC Syst Biol (2011) 0.85
Comparison of relative binding affinities of endocrine active compounds to fathead minnow and rainbow trout estrogen receptors. Environ Toxicol Chem (2005) 0.84
Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition. Toxicol Sci (2007) 0.84
Effects of a short-term exposure to the fungicide prochloraz on endocrine function and gene expression in female fathead minnows (Pimephales promelas). Aquat Toxicol (2011) 0.84
Temporal variation in the estrogenicity of a sewage treatment plant effluent and its biological significance. Environ Sci Technol (2008) 0.84
Progress towards development of an amphibian-based thyroid screening assay using Xenopus laevis. Organismal and thyroidal responses to the model compounds 6-propylthiouracil, methimazole, and thyroxine. Toxicol Sci (2005) 0.84
Development and validation of a 2,000-gene microarray for the fathead minnow (Pimephales promelas). Environ Toxicol Chem (2007) 0.83
DNA microarray-based ecotoxicological biomarker discovery in a small fish model species. Environ Toxicol Chem (2008) 0.83
Expression signatures for a model androgen and antiandrogen in the fathead minnow (Pimephales promelas) ovary. Environ Sci Technol (2009) 0.83
Reproductive maturation of the tropical clawed frog: Xenopus tropicalis. Gen Comp Endocrinol (2008) 0.83
Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone. Environ Toxicol Chem (2013) 0.83
Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor. Aquat Toxicol (2008) 0.83
A computational model of the hypothalamic-pituitary-gonadal axis in male fathead minnows exposed to 17alpha-ethinylestradiol and 17beta-estradiol. Toxicol Sci (2009) 0.82
A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis. Mutat Res (2011) 0.82
DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species. Environ Toxicol Chem (2008) 0.82
Propiconazole inhibits steroidogenesis and reproduction in the fathead minnow (Pimephales promelas). Toxicol Sci (2013) 0.82
Impacts of an anti-androgen and an androgen/anti-androgen mixture on the metabolite profile of male fathead minnow urine. Environ Sci Technol (2010) 0.82
Development of an adverse outcome pathway for acetylcholinesterase inhibition leading to acute mortality. Environ Toxicol Chem (2014) 0.82
Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation. Environ Toxicol Chem (2009) 0.81
Mechanistic computational model of ovarian steroidogenesis to predict biochemical responses to endocrine active compounds. Ann Biomed Eng (2007) 0.81
Transcription of key genes regulating gonadal steroidogenesis in control and ketoconazole- or vinclozolin-exposed fathead minnows. Toxicol Sci (2007) 0.81
Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish. Environ Toxicol Chem (2011) 0.81
Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: II. Computational modeling. Toxicol Sci (2013) 0.81
Ecotoxicogenomics to support ecological risk assessment: a case study with bisphenol A in fish. Environ Sci Technol (2011) 0.81
Perturbation of gene expression and steroidogenesis with in vitro exposure of fathead minnow ovaries to ketoconazole. Mar Environ Res (2008) 0.81
Fishy aroma of social status: urinary chemo-signalling of territoriality in male fathead minnows (Pimephales promelas). PLoS One (2012) 0.81
Mechanistic basis for estrogenic effects in fathead minnow (Pimephales promelas) following exposure to the androgen 17alpha-methyltestosterone: conversion of 17alpha-methyltestosterone to 17alpha-methylestradiol. Aquat Toxicol (2004) 0.80
Gene expression profiling of the androgen receptor antagonists flutamide and vinclozolin in zebrafish (Danio rerio) gonads. Aquat Toxicol (2010) 0.80
Transcriptional regulatory dynamics of the hypothalamic-pituitary-gonadal axis and its peripheral pathways as impacted by the 3-beta HSD inhibitor trilostane in zebrafish (Danio rerio). Ecotoxicol Environ Saf (2011) 0.80
Overview of data and conceptual approaches for derivation of quantitative structure-activity relationships for ecotoxicological effects of organic chemicals. Environ Toxicol Chem (2003) 0.80
Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals. Ecotoxicol Environ Saf (2007) 0.80
Characterization of the androgen-sensitive MDA-kb2 cell line for assessing complex environmental mixtures. Environ Toxicol Chem (2010) 0.80
Investigating alternatives to the fish early-life stage test: a strategy for discovering and annotating adverse outcome pathways for early fish development. Environ Toxicol Chem (2013) 0.80
Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas). Environ Toxicol Chem (2012) 0.80
Molecular characterization of thyroid toxicity: anchoring gene expression profiles to biochemical and pathologic end points. Environ Health Perspect (2005) 0.79
Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis. Aquat Toxicol (2010) 0.79
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb. Aquat Toxicol (2007) 0.79
Uptake and depuration of nonionic organic contaminants from sediment by the oligochaete, Lumbriculus variegatus. Environ Toxicol Chem (2003) 0.78
Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin beta subunit mRNAs to support endocrine disruptor research. Comp Biochem Physiol C Toxicol Pharmacol (2006) 0.78
Integrated assessment of runoff from livestock farming operations: Analytical chemistry, in vitro bioassays, and in vivo fish exposures. Environ Toxicol Chem (2014) 0.78
Comparing the effects of stage and duration of retinoic Acid exposure on amphibian limb development: chronic exposure results in mortality, not limb malformations. Toxicol Sci (2003) 0.78
What is normal? A characterization of the values and variability in reproductive endpoints of the fathead minnow, Pimephales promelas. Comp Biochem Physiol C Toxicol Pharmacol (2007) 0.78
Discovery and validation of gene classifiers for endocrine-disrupting chemicals in zebrafish (danio rerio). BMC Genomics (2012) 0.78
In vivo assessment and potential diagnosis of xenobiotics that perturb the thyroid pathway: Proteomic analysis of Xenopus laevis brain tissue following exposure to model T4 inhibitors. Comp Biochem Physiol Part D Genomics Proteomics (2010) 0.78
Screening complex effluents for estrogenic activity with the T47D-KBluc cell bioassay: assay optimization and comparison with in vivo responses in fish. Environ Toxicol Chem (2011) 0.78
Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem (2012) 0.78
Trenbolone causes mortality and altered sexual differentiation in Xenopus tropicalis during larval development. Environ Toxicol Chem (2012) 0.77
Evaluation of a commercial kit for measuring vitellogenin in the fathead minnow (Pimephales promelas). Ecotoxicol Environ Saf (2006) 0.77
Effects of methoprene, its metabolites, and breakdown products on retinoid-activated pathways in transfected cell lines. Environ Toxicol Chem (2004) 0.77
Proteomic analysis of zebrafish brain tissue following exposure to the pesticide prochloraz. Aquat Toxicol (2011) 0.77
Using transcriptomic tools to evaluate biological effects across effluent gradients at a diverse set of study sites in Minnesota, USA. Environ Sci Technol (2014) 0.77
Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis. Gen Comp Endocrinol (2010) 0.77
The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions. Environ Health Perspect (2016) 0.77
Computational toxicology: framework, partnerships, and program development. September 29-30, 2003, Research Triangle Park, North Carolina. Reprod Toxicol (2005) 0.77
Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole. Aquat Toxicol (2012) 0.77
Short-term study investigating the estrogenic potency of diethylstilbesterol in the fathead minnow (Pimephales promelas). Environ Sci Technol (2012) 0.76
I. Effects of a dopamine receptor antagonist on fathead minnow, Pimephales promelas, reproduction. Ecotoxicol Environ Saf (2009) 0.76
A method for the determination of genetic sex in the fathead minnow, Pimephales promelas, to support testing of endocrine-active chemicals. Environ Sci Technol (2011) 0.76
II: Effects of a dopamine receptor antagonist on fathead minnow dominance behavior and ovarian gene expression in the fathead minnow and zebrafish. Ecotoxicol Environ Saf (2009) 0.76
Characterization of ontogenetic changes in gene expression in the fathead minnow (Pimephales promelas). Environ Toxicol Chem (2009) 0.76