Published in Ann Neurol on April 01, 2003
CJD (Creutzfeldt-Jakob Disease) Quinacrine Study | NCT00183092
Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial. Lancet Neurol (2009) 2.41
Rapidly progressive dementias and the treatment of human prion diseases. Expert Opin Pharmacother (2010) 1.00
Toxicity of quinacrine can be reduced by co-administration of P-glycoprotein inhibitor in sporadic Creutzfeldt-Jakob disease. Cell Mol Neurobiol (2004) 0.85
Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC. Hepatology (2006) 5.46
Netrin-1 controls colorectal tumorigenesis by regulating apoptosis. Nature (2004) 3.05
Surveillance of duodenal adenomas in familial adenomatous polyposis reveals high cumulative risk of advanced disease. J Clin Oncol (2004) 2.31
Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated colon and rectum tumour/carcinoma. Neuroendocrinology (2007) 2.27
Papillary tumor of the pineal region. Am J Surg Pathol (2003) 2.13
Incidence of sarcoma histotypes and molecular subtypes in a prospective epidemiological study with central pathology review and molecular testing. PLoS One (2011) 2.13
Long-term survival (5-20 years) after pancreatectomy for pancreatic ductal adenocarcinoma: a series of 30 patients collected from 3 institutions. Pancreas (2008) 2.05
A standard international version of the Drug Burden Index for cross-national comparison of the functional burden of medications in older people. J Am Geriatr Soc (2013) 1.96
Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer. Proc Natl Acad Sci U S A (2008) 1.95
ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prognostic stratification. Neuroendocrinology (2009) 1.92
ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes. Neuroendocrinology (2012) 1.86
Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium. Brain Pathol (2008) 1.85
Standardization of preanalytical aspects of cerebrospinal fluid biomarker testing for Alzheimer's disease diagnosis: a consensus paper from the Alzheimer's Biomarkers Standardization Initiative. Alzheimers Dement (2011) 1.85
Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. PLoS One (2010) 1.84
Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies. Gastroenterology (2007) 1.83
Non-alcoholic fatty liver disease in liver transplant recipients: another story of "seed and soil". Am J Gastroenterol (2009) 1.83
Shining a light on posterior cortical atrophy. Alzheimers Dement (2012) 1.77
CAPN3 mutations in patients with idiopathic eosinophilic myositis. Ann Neurol (2006) 1.73
Treatment of recurrent hepatitis C after liver transplantation: a pilot study of peginterferon alfa-2b and ribavirin combination. J Hepatol (2004) 1.71
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment. Proc Natl Acad Sci U S A (2003) 1.69
Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis. Int J Cancer (2003) 1.67
Impact of chronic Helicobacter pylori infection on Alzheimer's disease: preliminary results. Neurobiol Aging (2011) 1.63
Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Cancer Lett (2011) 1.62
Sentinel lymph node biopsy is not accurate in predicting lymph node status for patients with cervical carcinoma. Cancer (2004) 1.62
Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe Consortium. J Neuropathol Exp Neurol (2006) 1.56
Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas. PLoS Genet (2009) 1.55
Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL. Gastroenterology (2011) 1.55
Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium. Acta Neuropathol (2008) 1.51
Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update. Biomark Med (2012) 1.48
BRAF mutation status in gastrointestinal stromal tumors. Am J Clin Pathol (2010) 1.47
Patterns of bidirectional communication between cortex and basal ganglia during movement in patients with Parkinson disease. J Neurosci (2008) 1.47
Episodic weakness due to mitochondrial DNA MT-ATP6/8 mutations. Neurology (2013) 1.45
Exhaustive analysis of BH4 and dopamine biosynthesis genes in patients with Dopa-responsive dystonia. Brain (2009) 1.44
Intraductal papillary-mucinous tumors of the pancreas: predictive criteria of malignancy according to pathological examination of 53 cases. Arch Surg (2002) 1.44
N19S, a new SOD1 mutation in sporadic amyotrophic lateral sclerosis: no evidence for disease causation. Ann Neurol (2003) 1.44
[Intestinal ganglioneuromatosis diagnosed in adult patients]. Gastroenterol Clin Biol (2003) 1.44
Bilateral subthalamic nucleus stimulation in advanced Parkinson's disease: five year follow-up. J Neurol (2009) 1.43
Treatment of refractory ulcerative proctitis with argon plasma coagulation: case report. Gastrointest Endosc (2004) 1.43
Word processing in Parkinson's disease is impaired for action verbs but not for concrete nouns. Neuropsychologia (2007) 1.43
C9orf72 repeat expansions are a rare genetic cause of parkinsonism. Brain (2013) 1.42
Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa. Brain (2006) 1.41
FXTAS: new insights and the need for revised diagnostic criteria. Neurology (2012) 1.39
Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. Mol Endocrinol (2002) 1.36
Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours. Brain (2012) 1.34
An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology. Acta Neuropathol (2012) 1.33
Are G3 ENETS neuroendocrine neoplasms heterogeneous? Endocr Relat Cancer (2013) 1.31
Vascular development and differentiation during human liver organogenesis. Anat Rec (Hoboken) (2008) 1.30
Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies. Nucleic Acids Res (2007) 1.28
Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium. Acta Neuropathol (2009) 1.27
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum Mol Genet (2007) 1.27
Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake. J Hepatol (2010) 1.26
Well-differentiated pancreatic nonfunctioning tumors/carcinoma. Neuroendocrinology (2007) 1.26
GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation. J Hepatol (2011) 1.25
Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS One (2008) 1.24
Guillain-Barre syndrome, influenzalike illnesses, and influenza vaccination during seasons with and without circulating A/H1N1 viruses. Am J Epidemiol (2011) 1.21
Well-differentiated pancreatic tumor/carcinoma: insulinoma. Neuroendocrinology (2007) 1.21
DCC constrains tumour progression via its dependence receptor activity. Nature (2011) 1.21
A simple score for predicting alcohol relapse after liver transplantation: results from 387 patients over 15 years. Arch Intern Med (2007) 1.21
NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors. Gastroenterology (2008) 1.19
PPARγ contributes to PKM2 and HK2 expression in fatty liver. Nat Commun (2012) 1.18
Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium. Acta Neuropathol (2009) 1.17
Treatments for dysarthria in Parkinson's disease. Lancet Neurol (2004) 1.17
Contribution of Jules Froment to the study of parkinsonian rigidity. Mov Disord (2007) 1.16
Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: a brain biopsy study. Int J Biochem Cell Biol (2004) 1.16
Chordoid glioma of the third ventricle: a report of two new cases, with further evidence supporting an ependymal differentiation, and review of the literature. Am J Surg Pathol (2002) 1.15
Beyond PrP res type 1/type 2 dichotomy in Creutzfeldt-Jakob disease. PLoS Pathog (2008) 1.14
Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression. Proc Natl Acad Sci U S A (2009) 1.13
Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium. Acta Neuropathol (2008) 1.13
Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage. Diabetes (2010) 1.13
VEGF secretion by neuroendocrine tumor cells is inhibited by octreotide and by inhibitors of the PI3K/AKT/mTOR pathway. Neuroendocrinology (2010) 1.12
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells. Nat Cell Biol (2013) 1.12
Emotion recognition and genetic vulnerability to schizophrenia. Br J Psychiatry (2007) 1.12
Cerebrospinal fluid collection tubes: a critical issue for Alzheimer disease diagnosis. Clin Chem (2012) 1.11
Complete response of hepatocellular carcinoma with systemic combination chemotherapy: not to get out the chemotherapy? Eur J Gastroenterol Hepatol (2010) 1.10
Leptin modulates the expression of secreted and membrane-associated mucins in colonic epithelial cells by targeting PKC, PI3K, and MAPK pathways. Am J Physiol Gastrointest Liver Physiol (2007) 1.10
Genetic Creutzfeldt-Jakob disease associated with the E200K mutation: characterization of a complex proteinopathy. Acta Neuropathol (2010) 1.10
Assessment of alpha-synuclein pathology: a study of the BrainNet Europe Consortium. J Neuropathol Exp Neurol (2008) 1.08
Noninvasive diagnosis and prognosis of liver cirrhosis: a comparison of biological scores, elastometry, and metabolic liver function tests. Eur J Gastroenterol Hepatol (2010) 1.08
Matrilysin 1 influences colon carcinoma cell migration by cleavage of the laminin-5 beta3 chain. Cancer Res (2006) 1.07
Globus pallidus internus stimulation in primary generalized dystonia: a H215O PET study. Brain (2004) 1.06
Liver steatosis quantification using magnetic resonance imaging: a prospective comparative study with liver biopsy. J Comput Assist Tomogr (2009) 1.06
Low microvessel density is an unfavorable histoprognostic factor in pancreatic endocrine tumors. Gastroenterology (2003) 1.05
Dumbbell-shaped epidural capillary hemangioma. AJNR Am J Neuroradiol (2003) 1.04
A new mutation of the tau gene, G303V, in early-onset familial progressive supranuclear palsy. Arch Neurol (2005) 1.04
Predictive value of multimodality MRI using conventional, perfusion, and spectroscopy MR in anaplastic transformation of low-grade oligodendrogliomas. J Neurooncol (2009) 1.04
Sporadic desmoid tumor. An exceptional cause of cystic pancreatic lesion. JOP (2008) 1.04
A naturally occurring human minidysferlin protein repairs sarcolemmal lesions in a mouse model of dysferlinopathy. Sci Transl Med (2010) 1.04
The French series of autosomal dominant early onset Alzheimer's disease cases: mutation spectrum and cerebrospinal fluid biomarkers. J Alzheimers Dis (2012) 1.03
Expression of hepatitis C virus proteins in epithelial intestinal cells in vivo. J Gen Virol (2004) 1.03
[Mixed endocrine tumors]. Ann Pathol (2005) 1.02
The CXCL7/CXCR1/2 axis is a key driver in the growth of clear cell renal cell carcinoma. Cancer Res (2013) 1.01
The estimated incidence of gastrointestinal stromal tumors in France. Results of PROGIST study conducted among pathologists. Bull Cancer (2010) 1.01
Correlations between soluble α/β forms of amyloid precursor protein and Aβ38, 40, and 42 in human cerebrospinal fluid. Brain Res (2010) 1.01