Published in Haematologica on April 01, 2003
One strategy for cell and gene therapy: harnessing the power of adult stem cells to repair tissues. Proc Natl Acad Sci U S A (2003) 2.65
Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer. Br J Cancer (2011) 1.69
Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance. Biochem Pharmacol (2012) 1.65
Visualization and enrichment of live putative cancer stem cell populations following p53 inactivation or Bax deletion using non-toxic fluorescent dyes. Cancer Biol Ther (2009) 1.43
Concise review: Kidney stem/progenitor cells: differentiate, sort out, or reprogram? Stem Cells (2010) 1.23
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics. Endocrinology (2007) 1.13
Oncogene-specific formation of chemoresistant murine hepatic cancer stem cells. Hepatology (2012) 1.11
A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity. Blood (2005) 1.10
Advances in complex multiparameter flow cytometry technology: Applications in stem cell research. Cytometry B Clin Cytom (2009) 1.10
Transcriptional profiling of bipotential embryonic liver cells to identify liver progenitor cell surface markers. Stem Cells (2007) 1.09
Alpha-fetoprotein, stem cells and cancer: how study of the production of alpha-fetoprotein during chemical hepatocarcinogenesis led to reaffirmation of the stem cell theory of cancer. Tumour Biol (2008) 1.08
Fetal and adult liver stem cells for liver regeneration and tissue engineering. J Cell Mol Med (2006) 1.07
Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control. Dev Cell (2013) 1.07
MicroRNAs involved in neoplastic transformation of liver cancer stem cells. J Exp Clin Cancer Res (2010) 1.04
Liver-specific gene expression in mesenchymal stem cells is induced by liver cells. World J Gastroenterol (2005) 1.03
Side population cells derived from adult human liver generate hepatocyte-like cells in vitro. Dig Dis Sci (2005) 1.02
Hepatocyte progenitors in man and in rodents--multiple pathways, multiple candidates. Int J Exp Pathol (2005) 0.95
Physiological variations of stem cell factor and stromal-derived factor-1 in murine models of liver injury and regeneration. Liver Int (2008) 0.91
Identification and characterization of side population cells in embryonic stem cell cultures. Stem Cells Dev (2009) 0.90
Characterization of free-floating spheres from human trabecular meshwork (HTM) cell culture in vitro. Exp Eye Res (2005) 0.89
IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential. Stem Cells (2008) 0.84
Doxorubicin and 5-fluorouracil resistant hepatic cancer cells demonstrate stem-like properties. Cytotechnology (2012) 0.81
Hepatic cancer stem cells and drug resistance: Relevance in targeted therapies for hepatocellular carcinoma. World J Hepatol (2010) 0.80
Stem cell antigen 1-positive mesenchymal cells are the origin of follicular cells during thyroid regeneration. PLoS One (2013) 0.79
Adult pancreas side population cells expand after β cell injury and are a source of insulin-secreting cells. PLoS One (2012) 0.79
Thyroid regeneration: how stem cells play a role? Front Endocrinol (Lausanne) (2014) 0.78
The phenotypic characters of the stem cells in hepatocytes during liver regeneration: the expression of the Bcrp1/Abcg2 membrane transporter and the Hoechst 33342 export. Dokl Biol Sci (2004) 0.77
Multipotent stem cells of the heart-do they have therapeutic promise? Front Physiol (2015) 0.76
Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cells. Thyroid (2015) 0.76
Side Population Cells From an Immortalized Human Liver Epithelial Cell Line Exhibit Hepatic Stem-Like Cell Properties. Cell Med (2012) 0.75
Young Bone-Marrow Sca-1(+) Stem Cells Rejuvenate the Aged Heart and Improve Function after Injury through PDGFRβ-Akt pathway. Sci Rep (2017) 0.75
Optimised protocols for the identification of the murine cardiac side population. Stem Cell Rev (2013) 0.75
Adult stem cells and cancer stem cells: tie in or tear apart? J Cancer Res Clin Oncol (2005) 0.75
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med (2008) 11.49
CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest (2011) 6.38
Inducible apoptosis as a safety switch for adoptive cell therapy. N Engl J Med (2011) 6.14
Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol (2002) 5.74
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol (2007) 5.48
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients. Blood (2009) 4.98
Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet (2011) 4.85
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals. Nat Med (2006) 4.42
Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell (2007) 4.06
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes. Blood (2004) 4.01
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer. Blood (2007) 3.94
Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol (2004) 3.94
Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature (2010) 3.93
Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood (2011) 3.82
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69
Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins. J Clin Oncol (2013) 3.65
Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease. J Exp Med (2004) 3.57
A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells. Mol Ther (2005) 3.18
Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science (2002) 3.18
An inducible caspase 9 safety switch for T-cell therapy. Blood (2005) 2.93
Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nat Med (2003) 2.91
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. Blood (2009) 2.79
T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood (2006) 2.68
The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell (2008) 2.57
Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease. Blood (2007) 2.50
Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci U S A (2002) 2.39
Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol (2011) 2.38
Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation. Biol Blood Marrow Transplant (2007) 2.33
Mouse hematopoietic stem cell identification and analysis. Cytometry A (2009) 2.32
CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood (2007) 2.27
Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. J Clin Invest (2003) 2.23
Inflammatory signals regulate hematopoietic stem cells. Trends Immunol (2011) 2.21
Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood (2013) 2.13
Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood (2007) 2.11
The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood (2006) 2.10
Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects. Blood (2010) 2.06
Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood (2006) 1.98
Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood (2002) 1.98
Midlife moments. Mol Ther (2011) 1.97
Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study. Lancet (2009) 1.96
Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation. Blood (2013) 1.95
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation. Blood (2006) 1.93
Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy. Blood (2002) 1.89
Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood (2011) 1.86
Design and development of therapies using chimeric antigen receptor-expressing T cells. Immunol Rev (2014) 1.81
Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs). Blood (2006) 1.75
Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood (2015) 1.75
Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes. J Exp Med (2004) 1.72
Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections. Mol Ther (2012) 1.72
Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell (2012) 1.71
Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy. J Virol (2007) 1.70
Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell (2009) 1.69
Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest (2004) 1.67
Hypoxic adipocytes pattern early heterotopic bone formation. Am J Pathol (2007) 1.62
Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation. Blood (2002) 1.59
Prompt versus preemptive intervention for EBV lymphoproliferative disease. Blood (2004) 1.57
Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells. Blood (2004) 1.56
Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses. Blood (2003) 1.55
Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications. Blood (2003) 1.54
MOABS: model based analysis of bisulfite sequencing data. Genome Biol (2014) 1.53
Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients. Blood (2008) 1.52
Evidence for diversity in transcriptional profiles of single hematopoietic stem cells. PLoS Genet (2006) 1.51
Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma. J Immunother (2010) 1.50
Isolation and characterization of functional mammary gland stem cells. Cell Prolif (2003) 1.49
Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics. Exp Hematol (2007) 1.48
Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proc Natl Acad Sci U S A (2003) 1.47
Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol (2005) 1.45
Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts. Stem Cells (2004) 1.42
Target antigen expression on a professional antigen-presenting cell induces superior proliferative antitumor T-cell responses via chimeric T-cell receptors. J Immunother (2005) 1.41
Genetic modification of T lymphocytes for adoptive immunotherapy. Mol Ther (2004) 1.41
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood (2012) 1.41
Autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for the treatment of persistent active EBV infection. Blood (2002) 1.40
The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol (2010) 1.40
CD45 monoclonal antibody-mediated cytolysis of human NK and T lymphoma cells. Haematologica (2006) 1.39
Introducing a new ASGCT forum for publication of methodology and clinical development in gene, cell, and oligonucleotide therapies. Mol Ther (2012) 1.39
Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506). Blood (2009) 1.39
Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant. Mol Ther (2013) 1.38
Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother (2010) 1.38
A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood (2013) 1.38
Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood (2003) 1.38
Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy. J Immunother (2003) 1.37
Nucleofection of DCs to generate Multivirus-specific T cells for prevention or treatment of viral infections in the immunocompromised host. Mol Ther (2009) 1.36
Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis. Blood (2005) 1.36
Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet (2012) 1.35
The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease. J Immunother (2004) 1.35
Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen. Biol Blood Marrow Transplant (2008) 1.35
Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7. Mol Ther (2009) 1.35
Immunotherapy of human cancers using gene modified T lymphocytes. Curr Gene Ther (2009) 1.29
High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells. Blood (2011) 1.29
Flow cytometry analysis of murine hematopoietic stem cells. Cytometry A (2012) 1.29
Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells. Exp Hematol (2010) 1.28
Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor. J Immunother (2008) 1.25
Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J Biol Chem (2013) 1.24