Published in Cancer Res on April 15, 2003
The molecular biology of head and neck cancer. Nat Rev Cancer (2010) 9.84
Cancer as an evolutionary and ecological process. Nat Rev Cancer (2006) 9.33
Retracted Novel management of oral cancer: a paradigm of predictive oncology. Clin Med Res (2004) 2.14
Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions. Cancer Prev Res (Phila) (2009) 1.99
Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance. Mol Cell (2014) 1.99
Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology (2008) 1.97
Clinical implications and utility of field cancerization. Cancer Cell Int (2007) 1.91
Retracted Oral carcinogenesis and oral cancer chemoprevention: a review. Patholog Res Int (2011) 1.82
Molecular biology of squamous cell carcinoma of the head and neck. J Clin Pathol (2006) 1.76
Objective detection and delineation of oral neoplasia using autofluorescence imaging. Cancer Prev Res (Phila) (2009) 1.66
Breast cancer chemoprevention: old and new approaches. J Biomed Biotechnol (2012) 1.57
Association between rectal optical signatures and colonic neoplasia: potential applications for screening. Cancer Res (2009) 1.53
Saliva protein biomarkers to detect oral squamous cell carcinoma in a high-risk population in Taiwan. Proc Natl Acad Sci U S A (2016) 1.51
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation. PLoS One (2009) 1.48
Biospecimen reporting for improved study quality (BRISQ). J Proteome Res (2011) 1.48
Current aspects on oral squamous cell carcinoma. Open Dent J (2012) 1.47
Epigenetic alterations in the breast: Implications for breast cancer detection, prognosis and treatment. Semin Cancer Biol (2009) 1.41
Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion. EMBO Rep (2013) 1.35
Light-scattering technologies for field carcinogenesis detection: a modality for endoscopic prescreening. Gastroenterology (2010) 1.33
Generation of a concise gene panel for outcome prediction in urinary bladder cancer. J Clin Oncol (2009) 1.32
Measuring mucosal blood supply in vivo with a polarization-gating probe. Appl Opt (2008) 1.29
Nanoscale changes in chromatin organization represent the initial steps of tumorigenesis: a transmission electron microscopy study. BMC Cancer (2014) 1.29
Field defects in progression to gastrointestinal tract cancers. Cancer Lett (2007) 1.28
Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer. Genes Chromosomes Cancer (2008) 1.26
Piwil2 is expressed in various stages of breast cancers and has the potential to be used as a novel biomarker. Int J Clin Exp Pathol (2010) 1.24
Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview. Am J Gastroenterol (2015) 1.22
On the stem cell origin of cancer. Am J Pathol (2010) 1.21
HDAC up-regulation in early colon field carcinogenesis is involved in cell tumorigenicity through regulation of chromatin structure. PLoS One (2013) 1.21
Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change. Nat Cell Biol (2014) 1.20
Clonal expansions in ulcerative colitis identify patients with neoplasia. Proc Natl Acad Sci U S A (2009) 1.17
Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer. PLoS Genet (2009) 1.16
Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression. Mod Pathol (2014) 1.16
DNA demethylation in normal colon tissue predicts predisposition to multiple cancers. Oncogene (2012) 1.15
Chromosomal aneusomy in bronchial high-grade lesions is associated with invasive lung cancer. Am J Respir Crit Care Med (2007) 1.14
Biospecimen Reporting for Improved Study Quality. Biopreserv Biobank (2011) 1.12
Gene expression in uninvolved oral mucosa of OSCC patients facilitates identification of markers predictive of OSCC outcomes. PLoS One (2012) 1.11
Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins. Gut (2006) 1.11
Multifocal epithelial tumors and field cancerization: stroma as a primary determinant. J Clin Invest (2014) 1.10
Aurora kinase inhibition overcomes cetuximab resistance in squamous cell cancer of the head and neck. Oncotarget (2011) 1.10
Differential gene expression in benign prostate epithelium of men with and without prostate cancer: evidence for a prostate cancer field effect. Clin Cancer Res (2010) 1.09
Review of photodynamic therapy in actinic keratosis and basal cell carcinoma. Ther Clin Risk Manag (2008) 1.08
Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer. BMC Cancer (2006) 1.08
Concordance of metabolic enzyme genotypes assayed from paraffin-embedded, formalin-fixed breast tumors and normal lymphatic tissue. Clin Epidemiol (2010) 1.06
An updated overview of HPV-associated head and neck carcinomas. Oncotarget (2014) 1.06
Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients. BMC Cancer (2013) 1.04
Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer. J Natl Cancer Inst (2014) 1.04
Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma. Mutat Res (2010) 1.03
Squamous cell carcinoma of the oral cavity and circulating tumour cells. World J Clin Oncol (2014) 1.02
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature. Oral Oncol (2007) 1.02
The relationship between occupational sun exposure and non-melanoma skin cancer: clinical basics, epidemiology, occupational disease evaluation, and prevention. Dtsch Arztebl Int (2012) 1.00
Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer. Mol Cancer (2014) 1.00
Markers of field cancerization: proposed clinical applications in prostate biopsies. Prostate Cancer (2012) 1.00
Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age. Epigenetics (2014) 1.00
Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. Cancer (2010) 0.99
Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR. Cancer Cell Int (2010) 0.98
Changes in abundance of oral microbiota associated with oral cancer. PLoS One (2014) 0.97
A dynamic oral cancer field: unraveling the underlying biology and its clinical implication. Am J Surg Pathol (2009) 0.97
Photodynamic therapy of early stage oral cavity and oropharynx neoplasms: an outcome analysis of 170 patients. Eur Arch Otorhinolaryngol (2010) 0.96
Hereditary ovarian cancer and two-compartment tumor metabolism: epithelial loss of BRCA1 induces hydrogen peroxide production, driving oxidative stress and NFκB activation in the tumor stroma. Cell Cycle (2012) 0.95
Spatially resolved optical and ultrastructural properties of colorectal and pancreatic field carcinogenesis observed by inverse spectroscopic optical coherence tomography. J Biomed Opt (2014) 0.95
The Fanconi anemia pathway: repairing the link between DNA damage and squamous cell carcinoma. Mutat Res (2013) 0.95
DNA methylation in circulating tumour DNA as a biomarker for cancer. Biomark Insights (2008) 0.95
Understanding carcinogenesis for fighting oral cancer. J Oncol (2011) 0.94
E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J Invest Dermatol (2008) 0.94
Epigenetic changes in colorectal cancer. Chin J Cancer (2011) 0.94
Laparoscopic resection of synchronous intraductal papillary mucinous neoplasms: a case report. World J Gastroenterol (2012) 0.94
Expressions of matrix metalloproteinase-9 (MMP-9), dentin sialophosphoprotein (DSPP), and osteopontin (OPN) at histologically negative surgical margins may predict recurrence of oral squamous cell carcinoma. Oncotarget (2012) 0.93
A second field metachronous Merkel cell carcinoma of the lip and the palatine tonsil confirmed by microarray-based comparative genomic hybridisation. Virchows Arch (2005) 0.92
Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development. Hum Mol Genet (2007) 0.92
Global detection of molecular changes reveals concurrent alteration of several biological pathways in nonsmall cell lung cancer cells. Mol Genet Genomics (2005) 0.92
TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors. J Transl Med (2013) 0.92
Epigenetic alterations in RASSF1A in human aberrant crypt foci. Carcinogenesis (2006) 0.92
Cell wars: regulation of cell survival and proliferation by cell competition. Essays Biochem (2012) 0.91
Cutaneous field cancerization: clinical, histopathological and therapeutic aspects. An Bras Dermatol (2013) 0.91
Canadian Optically-guided approach for Oral Lesions Surgical (COOLS) trial: study protocol for a randomized controlled trial. BMC Cancer (2011) 0.91
Spectral slope from the endoscopically-normal mucosa predicts concurrent colonic neoplasia: a pilot ex-vivo clinical study. Dis Colon Rectum (2008) 0.90
Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer. Neoplasia (2013) 0.90
Investigation of nuclear nano-morphology marker as a biomarker for cancer risk assessment using a mouse model. J Biomed Opt (2012) 0.90
Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis. Gastroenterology (2011) 0.89
Telomere DNA content in prostate biopsies predicts early rise in prostate-specific antigen after radical prostatectomy for prostate cancer. Urology (2009) 0.89
DNA methylation: a marker for carcinogen exposure and cancer risk. Environ Health Prev Med (2007) 0.89
Detection of early colorectal cancer development in the azoxymethane rat carcinogenesis model with Fourier domain low coherence interferometry. Biomed Opt Express (2010) 0.89
Socializing with MYC: cell competition in development and as a model for premalignant cancer. Cold Spring Harb Perspect Med (2014) 0.89
Field cancerization in the colon: a role for aberrant DNA methylation? Gastroenterol Rep (Oxf) (2014) 0.88
Oral field cancerization: current evidence and future perspectives. Oral Maxillofac Surg (2012) 0.88
Molecular diagnosis of response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer. J Am Coll Surg (2011) 0.87
Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers. Genes Chromosomes Cancer (2011) 0.87
Oral squamous cell carcinoma in relation to field precancerisation: pathobiology. Cancer Cell Int (2013) 0.87
End-binding protein 1 (EB1) up-regulation is an early event in colorectal carcinogenesis. FEBS Lett (2014) 0.87
Infection, stem cells and cancer signals. Curr Pharm Biotechnol (2011) 0.87
The translational significance of epithelial-mesenchymal transition in head and neck cancer. Clin Transl Med (2014) 0.86
Previous tumour as a prognostic factor in stage I non-small cell lung cancer. Thorax (2006) 0.86
On evolutionary origin of cancer. Cancer Cell Int (2005) 0.86
Genomic aberrations in normal appearing mucosa fields distal from oral potentially malignant lesions. Cell Oncol (Dordr) (2011) 0.86
CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers. Carcinogenesis (2008) 0.86
Cell migration leads to spatially distinct but clonally related airway cancer precursors. Thorax (2014) 0.86
Outcome of radiotherapy in T1 glottic carcinoma: a population-based study. Eur Arch Otorhinolaryngol (2008) 0.86
G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. J Thorac Oncol (2012) 0.86
Molecular analysis in combination with iodine staining may contribute to the risk prediction of esophageal squamous cell carcinoma. J Cancer Res Clin Oncol (2007) 0.85
A Cancer-Indicative microRNA Pattern in Normal Prostate Tissue. Int J Mol Sci (2013) 0.85
The molecular biology of head and neck cancer. Nat Rev Cancer (2010) 9.84
Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nat Rev Cancer (2008) 7.99
Notch1 functions as a tumor suppressor in mouse skin. Nat Genet (2003) 6.76
Dissecting the metastatic cascade. Nat Rev Cancer (2004) 6.32
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen. Int J Cancer (2007) 4.29
Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus. J Natl Cancer Inst (2004) 3.67
BAC to the future! or oligonucleotides: a perspective for micro array comparative genomic hybridization (array CGH). Nucleic Acids Res (2006) 3.32
Performance of immuno-positron emission tomography with zirconium-89-labeled chimeric monoclonal antibody U36 in the detection of lymph node metastases in head and neck cancer patients. Clin Cancer Res (2006) 2.71
Low levels of circulating invariant natural killer T cells predict poor clinical outcome in patients with head and neck squamous cell carcinoma. J Clin Oncol (2007) 2.47
Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program. Int J Radiat Oncol Biol Phys (2008) 2.13
Oral malignant melanoma: a review of the literature. Oral Oncol (2006) 1.70
Radiation dosimetry of 89Zr-labeled chimeric monoclonal antibody U36 as used for immuno-PET in head and neck cancer patients. J Nucl Med (2009) 1.68
Radioimmunotherapy of head and neck cancer xenografts using 131I-labeled antibody L19-SIP for selective targeting of tumor vasculature. J Nucl Med (2006) 1.62
(89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab. J Nucl Med (2005) 1.56
Nanocolloidal albumin-IRDye 800CW: a near-infrared fluorescent tracer with optimal retention in the sentinel lymph node. Eur J Nucl Med Mol Imaging (2012) 1.49
Selective neck dissection in the management of the neck after (chemo)radiotherapy for advanced head and neck cancer. Proposal for a classification update. Head Neck (2010) 1.42
Oral and oropharyngeal cancer in The Netherlands between 1989 and 2006: Increasing incidence, but not in young adults. Oral Oncol (2009) 1.41
Second primary tumors and field cancerization in oral and oropharyngeal cancer: molecular techniques provide new insights and definitions. Head Neck (2002) 1.41
Exploring dendritic cell based vaccines targeting survivin for the treatment of head and neck cancer patients. J Transl Med (2013) 1.40
Primary lung cancer after treatment of head and neck cancer without lymph node metastasis: is there a role for autofluorescence bronchoscopy? Lung Cancer (2008) 1.39
Peripheral blood IFN-gamma-secreting Valpha24+Vbeta11+ NKT cell numbers are decreased in cancer patients independent of tumor type or tumor load. Int J Cancer (2005) 1.39
Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities. Eur J Nucl Med Mol Imaging (2002) 1.36
Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30. Eur J Nucl Med Mol Imaging (2008) 1.36
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients. J Natl Cancer Inst (2008) 1.36
A genetic progression model of oral cancer: current evidence and clinical implications. J Oral Pathol Med (2004) 1.36
Advances and applications of oral cancer basic research. Oral Oncol (2011) 1.33
Increasing prevalence rates of HPV attributable oropharyngeal squamous cell carcinomas in the Netherlands as assessed by a validated test algorithm. Int J Cancer (2012) 1.31
Predictive modelling for swallowing dysfunction after primary (chemo)radiation: results of a prospective observational study. Radiother Oncol (2011) 1.31
A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus. Clin Cancer Res (2006) 1.30
A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer. Radiother Oncol (2009) 1.28
Elective and therapeutic selective neck dissection. Oral Oncol (2005) 1.26
Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology. Mol Cancer Ther (2008) 1.24
Quality of life and functional status in patients with cancer of the oral cavity and oropharynx: pretreatment values of a prospective study. Eur Arch Otorhinolaryngol (2007) 1.24
Management of Frey syndrome. Head Neck (2007) 1.24
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study. Clin Cancer Res (2004) 1.24
CGHMultiArray: exact P-values for multi-array comparative genomic hybridization data. Bioinformatics (2005) 1.23
Multiple head and neck tumors frequently originate from a single preneoplastic lesion. Am J Pathol (2002) 1.20
Expanding fields of genetically altered cells in head and neck squamous carcinogenesis. Semin Cancer Biol (2005) 1.20
Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion. Clin Cancer Res (2009) 1.19
Genetically altered fields as origin of locally recurrent head and neck cancer: a retrospective study. Clin Cancer Res (2004) 1.18
EGFR and KRAS mutations in lung carcinomas in the Dutch population: increased EGFR mutation frequency in malignant pleural effusion of lung adenocarcinoma. Cell Oncol (Dordr) (2012) 1.18
Screening for distant metastases in head and neck cancer patients by chest CT or whole body FDG-PET: a prospective multicenter trial. Radiother Oncol (2008) 1.17
In vivo bladder cancer diagnosis by high-volume Raman spectroscopy. Anal Chem (2010) 1.15
Neck dissection: then and now. Auris Nasus Larynx (2006) 1.14
Human papilloma virus in head and neck cancer: the need for a standardised assay to assess the full clinical importance. Eur J Cancer (2009) 1.14
Impact of radiation-induced xerostomia on quality of life after primary radiotherapy among patients with head and neck cancer. Int J Radiat Oncol Biol Phys (2007) 1.14
Comparative molecular and histological grading of epithelial dysplasia of the oral cavity and the oropharynx. J Pathol (2003) 1.13
Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma. Int J Cancer (2003) 1.12
The psychometric and clinical validity of the SWAL-QOL questionnaire in evaluating swallowing problems experienced by patients with oral and oropharyngeal cancer. Oral Oncol (2009) 1.12
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients. Cancer Res (2005) 1.12
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma. Blood (2002) 1.11
Mutated p53 as a molecular marker for the diagnosis of head and neck cancer. J Pathol (2002) 1.11
Post-traumatic cutaneous meningioma. J Laryngol Otol (2004) 1.11
Head and neck mucosal melanoma: experience with 42 patients, with emphasis on the role of postoperative radiotherapy. Head Neck (2008) 1.11
Quality of life after surgical treatment for oral and oropharyngeal cancer: a prospective longitudinal assessment of patients reconstructed by a microvascular flap. Oral Oncol (2007) 1.10
Computerized prospective screening for high levels of emotional distress in head and neck cancer patients and referral rate to psychosocial care. Oral Oncol (2009) 1.10
Genetic classification of oral and oropharyngeal carcinomas identifies subgroups with a different prognosis. Cell Oncol (2009) 1.10
Immunohistochemical profiling of caspase signaling pathways predicts clinical response to chemotherapy in primary nodal diffuse large B-cell lymphomas. Blood (2004) 1.08
The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation. Mol Cell Biol (2009) 1.08
Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma. Clin Cancer Res (2011) 1.08
Management of adult soft tissue sarcomas of the head and neck. Oral Oncol (2010) 1.08
Genetic reprogramming of tumor cells by zinc finger transcription factors. Proc Natl Acad Sci U S A (2005) 1.07
High-risk human papillomavirus-positive lung cancer: molecular evidence for a pattern of pulmonary metastasis. J Thorac Oncol (2013) 1.06
Prognostic factors in adult soft tissue sarcomas of the head and neck: a single-centre experience. Oral Oncol (2006) 1.06
A noninvasive genetic screening test to detect oral preneoplastic lesions. Lab Invest (2005) 1.06
Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review. Clin Nutr (2013) 1.06
Orphan granzymes find a home. Immunol Rev (2010) 1.05
Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation. Mol Immunol (2007) 1.05
Apical CD36 immunolocalization in human and porcine taste buds from circumvallate and foliate papillae. Acta Histochem (2010) 1.05
Chest CT and whole-body 18F-FDG PET are cost-effective in screening for distant metastases in head and neck cancer patients. J Nucl Med (2010) 1.05
Adenoid cystic carcinoma of the head and neck: a single-center analysis of 105 consecutive cases over a 30-year period. Oral Oncol (2013) 1.05
Proposal for a rational classification of neck dissections. Head Neck (2010) 1.04
Cordectomy by CO2 laser or radiotherapy for small T1a glottic carcinomas: costs, local control, survival, quality of life, and voice quality. Head Neck (2007) 1.04
Modern reconstruction techniques for oral and pharyngeal defects after tumor resection. Eur Arch Otorhinolaryngol (2007) 1.04