Published in J Biol Chem on May 06, 2003
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol (2011) 1.98
The neck of caveolae is a distinct plasma membrane subdomain that concentrates insulin receptors in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A (2007) 1.25
Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins. Mol Cell Biol (2006) 1.19
Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticity. Mol Biol Cell (2008) 1.18
Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome Biol (2005) 1.16
Filamin A modulates kinase activation and intracellular trafficking of epidermal growth factor receptors in human melanoma cells. Endocrinology (2009) 1.03
Filamin B serves as a molecular scaffold for type I interferon-induced c-Jun NH2-terminal kinase signaling pathway. Mol Biol Cell (2008) 0.98
Pro-prion binds filamin A, facilitating its interaction with integrin beta1, and contributes to melanomagenesis. J Biol Chem (2010) 0.95
Lipid rafts play an important role for maintenance of embryonic stem cell self-renewal. J Lipid Res (2010) 0.88
Insulin-like growth factor-binding protein-5-induced laminin gamma1 transcription requires filamin A. J Biol Chem (2010) 0.85
Adapter protein SH2B1beta binds filamin A to regulate prolactin-dependent cytoskeletal reorganization and cell motility. Mol Endocrinol (2011) 0.85
Sensing the insulin signaling pathway with an antibody array. Proteomics Clin Appl (2009) 0.84
Filamin and filamin-binding proteins in integrin-regulation and adhesion. Focus on: "FilaminA is required for vimentin-mediated cell adhesion and spreading". Am J Physiol Cell Physiol (2009) 0.83
The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors. Mol Cell Biochem (2010) 0.81
Concurrent quantification of proteome and phosphoproteome to reveal system-wide association of protein phosphorylation and gene expression. Mol Cell Proteomics (2009) 0.81
Filamin A phosphorylation by Akt promotes cell migration in response to arsenic. Oncotarget (2015) 0.81
The fatal attraction between pro-prion and filamin A: prion as a marker in human cancers. Biomark Med (2010) 0.80
Binding of pro-prion to filamin A: by design or an unfortunate blunder. Oncogene (2010) 0.78
Genes transactivated by hepatitis C virus core protein, a microarray assay. World J Gastroenterol (2005) 0.77
Signaling regulation and role of filamin A cleavage in Ca2+-stimulated migration of androgen receptor-deficient prostate cancer cells. Oncotarget (2017) 0.75
Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1. Proc Natl Acad Sci U S A (2007) 4.62
Metformin improves healthspan and lifespan in mice. Nat Commun (2013) 2.68
Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury. Kidney Int (2009) 2.53
Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway. Circ Res (2004) 1.85
Bax regulates primary necrosis through mitochondrial dynamics. Proc Natl Acad Sci U S A (2012) 1.80
Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells. Am J Respir Cell Mol Biol (2002) 1.78
(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function. Anesthesiology (2014) 1.76
A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting. Am J Respir Crit Care Med (2012) 1.74
Circulating adiponectin levels increase in rats on caloric restriction: the potential for insulin sensitization. Exp Gerontol (2004) 1.64
Activation of CaMKIIdeltaC is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis. J Biol Chem (2007) 1.61
Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation. J Biol Chem (2004) 1.58
Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice. Kidney Int (2009) 1.56
Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2011) 1.51
Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression. FEBS J (2009) 1.49
Clinical value of the quantitative expression of the three epitopes of CD34 in 300 cases of acute myeloid leukemia. Haematologica (2002) 1.44
Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes. Cell Signal (2008) 1.44
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. Diabetes (2008) 1.42
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. Am J Respir Crit Care Med (2007) 1.41
Wnt5A activates the calpain-mediated cleavage of filamin A. J Invest Dermatol (2009) 1.32
Pyrrolidine dithiocarbamate inhibits interleukin-6 signaling through impaired STAT3 activation and association with transcriptional coactivators in hepatocytes. J Biol Chem (2006) 1.30
Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. FASEB J (2003) 1.29
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2009) 1.28
Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent G(s) signaling during beta2-adrenergic stimulation. Circ Res (2002) 1.24
Filamin A-mediated down-regulation of the exchange factor Ras-GRF1 correlates with decreased matrix metalloproteinase-9 expression in human melanoma cells. J Biol Chem (2007) 1.23
S-glutathionylation impairs signal transducer and activator of transcription 3 activation and signaling. Endocrinology (2008) 1.23
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets. Am J Physiol Endocrinol Metab (2007) 1.22
TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective. Circulation (2002) 1.20
Role of the rice hexokinases OsHXK5 and OsHXK6 as glucose sensors. Plant Physiol (2008) 1.18
Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei. FEBS Lett (2005) 1.15
Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo. Transl Res (2008) 1.14
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. Cell Metab (2013) 1.14
Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. Biochem Biophys Res Commun (2003) 1.13
Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury. J Appl Physiol (1985) (2008) 1.08
Adipogenic signaling in rat white adipose tissue: modulation by aging and calorie restriction. Exp Gerontol (2007) 1.07
Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways. Nucleic Acids Res (2005) 1.07
Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells. J Biol Chem (2010) 1.06
Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain. J Thorac Cardiovasc Surg (2003) 1.05
National external quality assessment scheme for lymphocyte immunophenotyping in Belgium. Clin Chem Lab Med (2003) 1.05
A novel protein phosphatase indirectly regulates phytochrome-interacting factor 3 via phytochrome. Biochem J (2008) 1.05
Modulation of vascular smooth muscle cell migration by calcium/ calmodulin-dependent protein kinase II-delta 2. Am J Physiol Cell Physiol (2004) 1.04
Filamin A modulates kinase activation and intracellular trafficking of epidermal growth factor receptors in human melanoma cells. Endocrinology (2009) 1.03
Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells. Cell Signal (2013) 1.02
Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities. Anal Biochem (2007) 1.01
The importance of the nine-amino acid C-terminal sequence of exendin-4 for binding to the GLP-1 receptor and for biological activity. Regul Pept (2003) 1.01
Age-associated miRNA alterations in skeletal muscle from rhesus monkeys reversed by caloric restriction. Aging (Albany NY) (2013) 1.00
Phorbol esters increase MLC phosphorylation and actin remodeling in bovine lung endothelium without increased contraction. Am J Physiol Lung Cell Mol Physiol (2003) 0.99
Hypoxia, BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes. Circ Res (2002) 0.98
Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells. Xenobiotica (2012) 0.97
Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase. J Immunol (2012) 0.97
Induction of the apoptosis inhibitor ARC by Ras in human cancers. J Biol Chem (2010) 0.96
Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes. Circ Res (2004) 0.96
Role of CaM kinase II and ERK activation in thrombin-induced endothelial cell barrier dysfunction. Am J Physiol Lung Cell Mol Physiol (2003) 0.96
A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension. Circulation (2011) 0.96
Macrophage migration inhibitory factor governs endothelial cell sensitivity to LPS-induced apoptosis. Am J Respir Cell Mol Biol (2008) 0.95
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass. Aging Cell (2014) 0.94
Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Anal Chem (2007) 0.94
D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression. Psychopharmacology (Berl) (2014) 0.93
Heart failure after long-term supravalvular aortic constriction in rats. Am J Hypertens (2005) 0.93
Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema. Am J Respir Crit Care Med (2009) 0.93
Regulation of c-Jun N-terminal kinase and p38 kinase pathways in endothelial cells. Am J Respir Cell Mol Biol (2004) 0.92
Activation of heat shock factor 1 plays a role in pyrrolidine dithiocarbamate-mediated expression of the co-chaperone BAG3. Int J Biochem Cell Biol (2010) 0.90
What is hydroxynorketamine and what can it bring to neurotherapeutics? Expert Rev Neurother (2014) 0.90
The pro-angiogenic cytokine pleiotrophin potentiates cardiomyocyte apoptosis through inhibition of endogenous AKT/PKB activity. J Biol Chem (2007) 0.89
Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells. Mol Cell Endocrinol (2009) 0.89
The apoptosis inhibitor ARC alleviates the ER stress response to promote β-cell survival. Diabetes (2012) 0.89
Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease. Aging Cell (2012) 0.88
Mitogen-activated protein kinase-activated protein kinase 2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3. Am J Respir Cell Mol Biol (2014) 0.87
Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity. Anal Biochem (2011) 0.86
S-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity. J Mol Biol (2011) 0.86
Altered expression of pyrophosphate: fructose-6-phosphate 1-phosphotransferase affects the growth of transgenic Arabidopsis plants. Mol Cells (2009) 0.86
Binding of manumycin A inhibits IkappaB kinase beta activity. J Biol Chem (2005) 0.85
Fat-storing multilocular cells expressing CCR5 increase in the thymus with advancing age: potential role for CCR5 ligands on the differentiation and migration of preadipocytes. Int J Med Sci (2009) 0.85
Mycophenolate mofetil modifies kidney tubular injury and Foxp3+ regulatory T cell trafficking during recovery from experimental ischemia-reperfusion. Transpl Immunol (2010) 0.85
Proteomic identification of rhythmic proteins in rice seedlings. Biochim Biophys Acta (2011) 0.85
Metabolic profiling of an alcoholic fatty liver in zebrafish (Danio rerio). Mol Biosyst (2012) 0.84
Sensing the insulin signaling pathway with an antibody array. Proteomics Clin Appl (2009) 0.84
Cannabinoid receptor activation correlates with the proapoptotic action of the β2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells. J Pharmacol Exp Ther (2012) 0.83
In vivo biological activity of exendin (1-30). Endocrine (2005) 0.82
Novel Death Defying Domain in Met entraps the active site of caspase-3 and blocks apoptosis in hepatocytes. Hepatology (2014) 0.82
Hydroxychloroquine-induced apoptosis of chronic lymphocytic leukemia involves activation of caspase-3 and modulation of Bcl-2/bax/ratio. Leuk Lymphoma (2002) 0.81
Filamin A expression correlates with proliferation and invasive properties of human metastatic melanoma tumors: implications for survival in patients. J Cancer Res Clin Oncol (2014) 0.81
Pyrrolidine dithiocarbamate enhances hepatic glycogen synthesis and reduces FoxO1-mediated gene transcription in type 2 diabetic rats. Am J Physiol Endocrinol Metab (2011) 0.81
Patterns of gene and metabolite define the effects of extracellular osmolality on kidney collecting duct. J Proteome Res (2012) 0.81
Revisiting p53 and its effectors in ischemic heart injury. Cardiovasc Res (2006) 0.80
Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2. Antioxid Redox Signal (2014) 0.80
Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection. J Chromatogr A (2008) 0.79
The PHY domain is required for conformational stability and spectral integrity of the bacteriophytochrome from Deinococcus radiodurans. Biochem Biophys Res Commun (2008) 0.79
Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor. J Cell Biol (2003) 0.79
The biarylpyrazole compound AM251 alters mitochondrial physiology via proteolytic degradation of ERRα. Mol Pharmacol (2012) 0.77
Impact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translation. J Pharmacol Exp Ther (2011) 0.77
Sir-viving cardiac stress: cardioprotection mediated by a longevity gene. Circ Res (2004) 0.76