Published in Endocrinology on June 01, 2003
Inflammation, stress, and diabetes. J Clin Invest (2005) 17.11
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet (2005) 16.79
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab (2008) 5.53
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Dev Cell (2008) 4.26
Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc Natl Acad Sci U S A (2004) 3.67
PPARdelta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci U S A (2006) 3.29
Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle. Mol Cell Biol (2004) 3.12
Bone is a target for the antidiabetic compound rosiglitazone. Endocrinology (2003) 2.84
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A (2005) 2.63
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A (2004) 2.46
Oral antihyperglycemic therapy for type 2 diabetes mellitus. CMAJ (2005) 2.24
Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. J Clin Invest (2007) 2.23
FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity. Mol Cell Biol (2006) 1.70
PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proc Natl Acad Sci U S A (2008) 1.68
Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. J Lipid Res (2008) 1.63
A global view of transcriptional regulation by nuclear receptors: gene expression, factor localization, and DNA sequence analysis. Nucl Recept Signal (2008) 1.62
Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Metabolism (2007) 1.60
Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J Clin Invest (2010) 1.54
MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration. Am J Physiol Lung Cell Mol Physiol (2010) 1.52
PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1. J Clin Invest (2005) 1.49
Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply. J Biol Chem (2012) 1.43
PPAR delta as a therapeutic target in metabolic disease. FEBS Lett (2007) 1.38
Receptor interacting protein 140 regulates expression of uncoupling protein 1 in adipocytes through specific peroxisome proliferator activated receptor isoforms and estrogen-related receptor alpha. Mol Endocrinol (2007) 1.32
Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations. Mol Cell Biol (2005) 1.32
Peroxisome proliferator-activated receptor targets for the treatment of metabolic diseases. Mediators Inflamm (2013) 1.27
Effects of FXR in foam-cell formation and atherosclerosis development. Biochim Biophys Acta (2006) 1.26
Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. J Biol Chem (2010) 1.26
Mass spectrometry imaging with high resolution in mass and space. Histochem Cell Biol (2013) 1.25
PPARdelta agonism induces a change in fuel metabolism and activation of an atrophy programme, but does not impair mitochondrial function in rat skeletal muscle. J Physiol (2007) 1.23
Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proc Natl Acad Sci U S A (2006) 1.23
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. Genome Biol (2011) 1.22
A system-level investigation into the mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for cardiovascular disease treatment. PLoS One (2012) 1.20
Effects of dietary omega-3 polyunsaturated fatty acids on brain gene expression. Proc Natl Acad Sci U S A (2004) 1.20
Suppression mechanisms of COX assembly defects in yeast and human: insights into the COX assembly process. Biochim Biophys Acta (2008) 1.20
Peroxisome proliferator-activated receptor-alpha agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: relevance to multiple sclerosis. J Neurochem (2007) 1.19
PPAR{alpha} mediates the hypolipidemic action of fibrates by antagonizing FoxO1. Am J Physiol Endocrinol Metab (2006) 1.18
Discriminating different classes of toxicants by transcript profiling. Environ Health Perspect (2004) 1.16
Omega-3 Fatty Acids and PPARgamma in Cancer. PPAR Res (2008) 1.13
MALDI Imaging mass spectrometry: current frontiers and perspectives in pathology research and practice. Lab Invest (2015) 1.12
Nuclear receptors as drug targets for metabolic disease. Adv Drug Deliv Rev (2010) 1.10
Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. Cell Metab (2010) 1.09
Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells. Cancer Res (2008) 1.09
Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2). J Med Chem (2011) 1.08
Analysis of common and specific mechanisms of liver function affected by nitrotoluene compounds. PLoS One (2011) 1.08
Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha. PLoS One (2010) 1.07
Activation of peroxisome proliferator-activated receptor delta inhibits streptozotocin-induced diabetic nephropathy through anti-inflammatory mechanisms in mice. Diabetes (2011) 1.07
Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes. Mol Pharmacol (2008) 1.04
Modulation of nuclear factor-kappaB activity can influence the susceptibility to systemic lupus erythematosus. Immunology (2008) 1.01
Signal transduction via cannabinoid receptors. CNS Neurol Disord Drug Targets (2009) 0.99
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis. Carcinogenesis (2008) 0.99
Reduced peroxisome proliferator-activated receptor α expression is associated with decreased survival and increased tissue bacterial load in sepsis. Shock (2012) 0.99
Effect of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects and subjects with cardiovascular risk factors. Inflamm Res (2011) 0.98
Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats. Lipids Health Dis (2010) 0.97
PPARγ: a molecular link between systemic metabolic disease and benign prostate hyperplasia. Differentiation (2011) 0.97
PPARγ isoforms differentially regulate metabolic networks to mediate mouse prostatic epithelial differentiation. Cell Death Dis (2012) 0.97
Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans. J Physiol (2006) 0.95
Adopting new orphans into the family of metabolic regulators. Mol Endocrinol (2008) 0.95
Long chain acyl-CoA synthetase-3 is a molecular target for peroxisome proliferator-activated receptor delta in HepG2 hepatoma cells. J Biol Chem (2010) 0.94
Thiazolidinediones are partial agonists for the glucocorticoid receptor. Endocrinology (2008) 0.94
Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor gamma activity through the direct binding to the activation function-1 domain. J Biol Chem (2009) 0.94
Functional characterization of peroxisome proliferator-activated receptor-β/δ expression in colon cancer. Mol Carcinog (2011) 0.93
Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells. Immunology (2007) 0.92
Alcohol deranges hepatic lipid metabolism via altered transcriptional regulation. Trans Am Clin Climatol Assoc (2004) 0.92
Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm. J Lipid Res (2009) 0.92
Electrophilic nitro-fatty acids: anti-inflammatory mediators in the vascular compartment. Curr Opin Pharmacol (2010) 0.91
Identification and regulation of novel PPAR-gamma splice variants in human THP-1 macrophages. Biochim Biophys Acta (2006) 0.91
Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis. Toxicol Sci (2009) 0.91
Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation. BMC Genomics (2010) 0.91
Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity. PLoS One (2012) 0.90
Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth in a mouse mammary gland cancer cell line. Cancer Lett (2009) 0.89
Lipid metabolites as metabolic messengers in inter-organ communication. Trends Endocrinol Metab (2014) 0.89
Angiotensin II receptor blocker telmisartan enhances running endurance of skeletal muscle through activation of the PPAR-δ/AMPK pathway. J Cell Mol Med (2010) 0.89
Anti-obesity effect of resveratrol-amplified grape skin extracts on 3T3-L1 adipocytes differentiation. Nutr Res Pract (2012) 0.89
Identifying plausible adverse drug reactions using knowledge extracted from the literature. J Biomed Inform (2014) 0.89
Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures. Acta Crystallogr D Biol Crystallogr (2009) 0.89
The clinical biochemistry of obesity. Clin Biochem Rev (2004) 0.89
Comprehensive evidence-based assessment and prioritization of potential antidiabetic medicinal plants: a case study from canadian eastern james bay cree traditional medicine. Evid Based Complement Alternat Med (2011) 0.88
Role of central nervous system insulin resistance in fetal alcohol spectrum disorders. J Popul Ther Clin Pharmacol (2010) 0.88
"Sebocytes' makeup": novel mechanisms and concepts in the physiology of the human sebaceous glands. Pflugers Arch (2011) 0.87
Minireview: Nuclear receptor-controlled steroid hormone synthesis and metabolism. Mol Endocrinol (2009) 0.87
Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key? PPAR Res (2008) 0.87
Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2. Mol Cancer Ther (2010) 0.86
Genomic profiling reveals that transient adipogenic activation is a hallmark of mouse models of skeletal muscle regeneration. PLoS One (2013) 0.86
Does bilirubin prevent hepatic steatosis through activation of the PPARα nuclear receptor? Med Hypotheses (2016) 0.85
Ablation of promyelocytic leukemia protein (PML) re-patterns energy balance and protects mice from obesity induced by a Western diet. J Biol Chem (2013) 0.85
Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation. PPAR Res (2012) 0.85
The effects of estrogen and testosterone on gene expression in the rat mesenteric arteries. Vascul Pharmacol (2007) 0.85
Modeling obesity and its associated disorders in Drosophila. Physiology (Bethesda) (2013) 0.85
Α-synuclein neuropathology is controlled by nuclear hormone receptors and enhanced by docosahexaenoic acid in a mouse model for Parkinson's disease. Brain Pathol (2011) 0.84
1,1-bis(3'-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines. Mol Carcinog (2008) 0.84
Citrus ichangensis Peel Extract Exhibits Anti-Metabolic Disorder Effects by the Inhibition of PPARγ and LXR Signaling in High-Fat Diet-Induced C57BL/6 Mouse. Evid Based Complement Alternat Med (2012) 0.84
Effects of flaxseed oil supplementation on plasma adiponectin levels in dyslipidemic men. Eur J Nutr (2007) 0.84
Anti-obese effect of glucosamine and chitosan oligosaccharide in high-fat diet-induced obese rats. Mar Drugs (2015) 0.83
Pharmacological manipulations of CNS sirtuins: potential effects on metabolic homeostasis. Pharmacol Res (2010) 0.83
Effect of maternal nutrient restriction from early to midgestation on cardiac function and metabolism after adolescent-onset obesity. Am J Physiol Regul Integr Comp Physiol (2009) 0.82
Alterations of dendritic cells in sepsis: featured role in immunoparalysis. Biomed Res Int (2015) 0.82
Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells. Mol Cell Biol (2012) 0.82
Citrange fruit extracts alleviate obesity-associated metabolic disorder in high-fat diet-induced obese C57BL/6 mouse. Int J Mol Sci (2013) 0.81
PPARs as therapeutic targets for correction of inborn mitochondrial fatty acid oxidation disorders. J Inherit Metab Dis (2008) 0.81
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature (2011) 13.94
Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A (2003) 6.82
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell (2003) 6.53
AMPK and PPARdelta agonists are exercise mimetics. Cell (2008) 6.39
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner. Cancer Cell (2010) 6.33
Regulation of muscle fiber type and running endurance by PPARdelta. PLoS Biol (2004) 5.66
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. Genes Dev (2006) 5.53
Nuclear receptor expression links the circadian clock to metabolism. Cell (2006) 5.43
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (2009) 4.72
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell (2006) 4.64
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat Med (2004) 4.64
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature (2012) 4.15
A role for adult TLX-positive neural stem cells in learning and behaviour. Nature (2008) 4.14
Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy. Nat Med (2011) 4.10
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature (2008) 3.98
Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. Science (2003) 3.97
Muscle-specific Pparg deletion causes insulin resistance. Nat Med (2003) 3.93
PPARγ signaling and metabolism: the good, the bad and the future. Nat Med (2013) 3.71
Vitamin D receptor as an intestinal bile acid sensor. Science (2002) 3.64
Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell (2011) 3.64
PPAR-gamma regulates osteoclastogenesis in mice. Nat Med (2007) 3.59
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A (2001) 3.58
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature (2013) 3.33
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med (2012) 3.33
PPARdelta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci U S A (2006) 3.29
TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (2006) 3.26
Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature (2004) 3.25
PPAR delta: a dagger in the heart of the metabolic syndrome. J Clin Invest (2006) 3.17
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med (2013) 3.15
Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature (2016) 3.13
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metab (2007) 3.00
A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Mol Cell (2003) 2.85
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature (2002) 2.78
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function. Cell (2011) 2.75
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol Cell (2002) 2.69
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nat Med (2004) 2.61
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. Cell (2013) 2.58
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proc Natl Acad Sci U S A (2003) 2.46
PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proc Natl Acad Sci U S A (2009) 2.38
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. Genes Dev (2007) 2.36
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature (2011) 2.34
Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. Genes Dev (2010) 2.31
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Res (2011) 2.30
Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. Mol Cell Biol (2005) 2.28
International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacol Rev (2006) 2.22
The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proc Natl Acad Sci U S A (2002) 2.20
A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. J Biol Chem (2006) 2.20
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proc Natl Acad Sci U S A (2007) 2.19
ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metab (2007) 2.14
A Nuclear Receptor Atlas: macrophage activation. Mol Endocrinol (2005) 2.13
PPARdelta is a very low-density lipoprotein sensor in macrophages. Proc Natl Acad Sci U S A (2003) 2.10
A Nuclear Receptor Atlas: 3T3-L1 adipogenesis. Mol Endocrinol (2005) 2.06
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proc Natl Acad Sci U S A (2007) 2.05
International Union of Pharmacology. LX. Retinoic acid receptors. Pharmacol Rev (2006) 2.04
STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells. Immunity (2010) 1.98
Nuclear receptors: decoding metabolic disease. FEBS Lett (2007) 1.95
Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nat Cell Biol (2009) 1.94
Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells. Proc Natl Acad Sci U S A (2010) 1.88
A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature (2012) 1.85
Thermochemical flows couple the Earth's inner core growth to mantle heterogeneity. Nature (2008) 1.84
PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab (2010) 1.77
PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Proc Natl Acad Sci U S A (2008) 1.69
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. Elife (2012) 1.69
PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proc Natl Acad Sci U S A (2008) 1.68
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes Dev (2007) 1.67
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). Proc Natl Acad Sci U S A (2002) 1.65
Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk. Genes Dev (2007) 1.62
A methylation-mediator complex in hormone signaling. Genes Dev (2004) 1.61
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Mol Endocrinol (2003) 1.61
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proc Natl Acad Sci U S A (2011) 1.59
A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. Mol Pharmacol (2004) 1.59
Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. Trends Endocrinol Metab (2002) 1.58
Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proc Natl Acad Sci U S A (2006) 1.58
PPAR gamma signaling exacerbates mammary gland tumor development. Genes Dev (2004) 1.58
Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Proc Natl Acad Sci U S A (2005) 1.57
Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev (2006) 1.54
Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. Cancer Cell (2006) 1.53
Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes. Mol Cell (2012) 1.51
Revascularization of ischemic skeletal muscle by estrogen-related receptor-γ. Circ Res (2012) 1.51
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors. Proc Natl Acad Sci U S A (2004) 1.47
Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J Biol Chem (2004) 1.46
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proc Natl Acad Sci U S A (2008) 1.46
Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. Cell Metab (2006) 1.44
Isolation and characterization of mammalian HDAC10, a novel histone deacetylase. J Biol Chem (2001) 1.43
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. Cell Metab (2011) 1.43
Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. J Invest Dermatol (2007) 1.41
Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. Am J Physiol Endocrinol Metab (2003) 1.39
The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. J Biol Chem (2004) 1.38
Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting cardiomyocytes from oxidative damage. Cardiovasc Res (2007) 1.32
Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Development (2003) 1.29
Benefit of farnesoid X receptor inhibition in obstructive cholestasis. Proc Natl Acad Sci U S A (2006) 1.27
Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition. J Mol Biol (2003) 1.24
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis. Cell Metab (2012) 1.24