Published in J Biol Chem on May 13, 2003
The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase. Microbiol Mol Biol Rev (2006) 2.79
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics (2012) 1.98
Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs. PLoS Pathog (2010) 1.58
Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function. Biochim Biophys Acta (2006) 1.28
Genomic expression program involving the Haa1p-regulon in Saccharomyces cerevisiae response to acetic acid. OMICS (2010) 1.23
A genomic screen for yeast vacuolar membrane ATPase mutants. Genetics (2005) 1.22
Roles for sphingolipids in Saccharomyces cerevisiae. Adv Exp Med Biol (2010) 1.08
Yeast sphingolipids do not need to contain very long chain fatty acids. Biochem J (2007) 0.97
Acyl-CoA-binding protein, Acb1p, is required for normal vacuole function and ceramide synthesis in Saccharomyces cerevisiae. Biochem J (2004) 0.96
TOR complex 2-Ypk1 signaling maintains sphingolipid homeostasis by sensing and regulating ROS accumulation. Cell Rep (2014) 0.94
The yeast sphingolipid signaling landscape. Chem Phys Lipids (2013) 0.90
Congenital myopathy is caused by mutation of HACD1. Hum Mol Genet (2013) 0.89
Sphingolipid biosynthetic pathway genes FEN1 and SUR4 modulate amphotericin B resistance. Antimicrob Agents Chemother (2014) 0.88
Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function. Mol Genet Genomics (2008) 0.88
Nitrate Reductase Knockout Uncouples Nitrate Transport from Nitrate Assimilation and Drives Repartitioning of Carbon Flux in a Model Pennate Diatom. Plant Cell (2017) 0.87
Sphingomyelin is important for the cellular entry and intracellular localization of Helicobacter pylori VacA. Cell Microbiol (2010) 0.86
Loss of regulators of vacuolar ATPase function and ceramide synthesis results in multidrug sensitivity in Schizosaccharomyces pombe. Eukaryot Cell (2008) 0.86
A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. Genetics (2010) 0.85
Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids. J Lipid Res (2013) 0.83
Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. BMC Microbiol (2009) 0.81
Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease. Ageing Res Rev (2016) 0.80
pH-dependent localization of Btn1p in the yeast model for Batten disease. Dis Model Mech (2010) 0.80
Structure of Nanodisc Reconstituted Vacuolar ATPase Proton Channel: Definition of the Interaction of Rotor and Stator and Implications for Enzyme Regulation by Reversible Dissociation. J Biol Chem (2016) 0.77
Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae. PLoS One (2016) 0.75
Identification of Yeast Mutants Exhibiting Altered Sensitivity to Valinomycin and Nigericin Demonstrate Pleiotropic Effects of Ionophores on Cellular Processes. PLoS One (2016) 0.75
Sphingolipid functions in Saccharomyces cerevisiae. Biochim Biophys Acta (2002) 1.79
Functions and metabolism of sphingolipids in Saccharomyces cerevisiae. Prog Lipid Res (2006) 1.79
The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover. J Biol Chem (2008) 1.45
The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9. J Biol Chem (2005) 1.44
Pil1p and Lsp1p negatively regulate the 3-phosphoinositide-dependent protein kinase-like kinase Pkh1p and downstream signaling pathways Pkc1p and Ypk1p. J Biol Chem (2004) 1.34
Down-regulating sphingolipid synthesis increases yeast lifespan. PLoS Genet (2012) 1.20
The uracil transporter Fur4p associates with lipid rafts. J Biol Chem (2002) 1.11
Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles. Genetics (2006) 1.04
Mutant analysis reveals complex regulation of sphingolipid long chain base phosphates and long chain bases during heat stress in yeast. Yeast (2002) 0.97
Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan. Aging Cell (2013) 0.90
Sphingolipid signaling mediates iron toxicity. Cell Metab (2012) 0.86
Nutrients and the Pkh1/2 and Pkc1 protein kinases control mRNA decay and P-body assembly in yeast. J Biol Chem (2010) 0.85
Mannosyl-diinositolphospho-ceramide, the major yeast plasma membrane sphingolipid, governs toxicity of Kluyveromyces lactis zymocin. Eukaryot Cell (2005) 0.81
Functional characterization of the promoter for the mouse SPTLC2 gene, which encodes subunit 2 of serine palmitoyltransferase. FEBS Lett (2006) 0.80
Reducing signs of aging and increasing lifespan by drug synergy. Aging Cell (2013) 0.80
Lcb4p sphingoid base kinase localizes to the Golgi and late endosomes. FEBS Lett (2002) 0.80
Statement in response to asbestos industry efforts to prevent a ban on asbestos in Pakistan: chrysotile asbestos use is not safe and must be banned. Arch Environ Occup Health (2013) 0.79
SVF1 regulates cell survival by affecting sphingolipid metabolism in Saccharomyces cerevisiae. Genetics (2006) 0.79
Iron, glucose and intrinsic factors alter sphingolipid composition as yeast cells enter stationary phase. Biochim Biophys Acta (2012) 0.78
Not all diclofenac is equal. CMAJ (2013) 0.75
Common sense is not that common. Can Fam Physician (2008) 0.75
A reader and author respond to "The top ten unfounded health scares of the year". Medscape J Med (2008) 0.75
Correction: Drug synergy drives conserved pathways to increase fission yeast lifespan. PLoS One (2015) 0.75
February cover. Can Fam Physician (2010) 0.75