René E M Toes

Author PubWeight™ 120.89‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells. Eur J Immunol 2007 6.92
2 Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trial. Arthritis Rheum 2007 3.66
3 Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans. Hum Immunol 2005 3.65
4 A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: how to guide individual treatment decisions. Arthritis Rheum 2007 3.23
5 Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis. Arthritis Res Ther 2005 2.69
6 CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis. Arthritis Rheum 2003 2.68
7 Value of anti-modified citrullinated vimentin and third-generation anti-cyclic citrullinated peptide compared with second-generation anti-cyclic citrullinated peptide and rheumatoid factor in predicting disease outcome in undifferentiated arthritis and rheumatoid arthritis. Arthritis Rheum 2009 2.62
8 The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis. Arthritis Rheum 2006 2.46
9 Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells. Arthritis Rheum 2005 2.32
10 Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis Rheum 2010 2.27
11 Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis. Arthritis Rheum 2004 2.25
12 Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis. Arthritis Rheum 2009 1.80
13 Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts. Arthritis Rheum 2009 1.75
14 Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis. Ann Rheum Dis 2012 1.68
15 Retracted Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium. Arthritis Res Ther 2011 1.65
16 Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in four European populations. Arthritis Rheum 2010 1.57
17 Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis. Arthritis Rheum 2013 1.54
18 Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid. Arthritis Rheum 2010 1.53
19 Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes. Arthritis Rheum 2006 1.53
20 The HLA-DRB1 shared epitope alleles differ in the interaction with smoking and predisposition to antibodies to cyclic citrullinated peptide. Arthritis Rheum 2007 1.46
21 Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment. Arthritis Rheum 2007 1.38
22 Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis. Ann Rheum Dis 2013 1.37
23 Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators. J Immunol 2008 1.36
24 Marked differences in fine specificity and isotype usage of the anti-citrullinated protein antibody in health and disease. Arthritis Rheum 2008 1.35
25 The influence of ACPA status and characteristics on the course of RA. Nat Rev Rheumatol 2012 1.34
26 The devil in the details: the emerging role of anticitrulline autoimmunity in rheumatoid arthritis. J Immunol 2005 1.33
27 Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication. J Immunol 2004 1.29
28 Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development. Proc Natl Acad Sci U S A 2007 1.29
29 Identification of citrullinated vimentin peptides as T cell epitopes in HLA-DR4-positive patients with rheumatoid arthritis. Arthritis Rheum 2010 1.28
30 Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis. Arthritis Rheum 2005 1.27
31 Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis. Arthritis Rheum 2009 1.24
32 Transition of healthy to diseased synovial tissue in rheumatoid arthritis is associated with gain of mesenchymal/fibrotic characteristics. Arthritis Res Ther 2006 1.22
33 An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility. Arthritis Rheum 2005 1.20
34 Fc-glycosylation of IgG1 is modulated by B-cell stimuli. Mol Cell Proteomics 2011 1.20
35 Dendritic cells: vehicles for tolerance induction and prevention of autoimmune diseases. Immunobiology 2006 1.19
36 Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression. J Autoimmun 2013 1.17
37 The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis. Ann Rheum Dis 2010 1.15
38 The tumoricidal activity of memory CD8+ T cells is hampered by persistent systemic antigen, but full functional capacity is regained in an antigen-free environment. J Immunol 2004 1.10
39 Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance. Blood 2005 1.09
40 Immunomodulatory dendritic cells inhibit Th1 responses and arthritis via different mechanisms. J Immunol 2007 1.09
41 Immature dendritic cells suppress collagen-induced arthritis by in vivo expansion of CD49b+ regulatory T cells. J Immunol 2006 1.09
42 Pathogenic relevance of anti-citrullinated vimentin antibodies: comment on the article by Montes et al. Arthritis Rheum 2013 1.07
43 Confirmation of STAT4, IL2/IL21, and CTLA4 polymorphisms in rheumatoid arthritis. Arthritis Rheum 2009 1.07
44 Genetic variants in the prediction of rheumatoid arthritis. Ann Rheum Dis 2010 1.07
45 Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis. Arthritis Rheum 2011 1.06
46 Emerging patterns of risk factor make-up enable subclassification of rheumatoid arthritis. Arthritis Rheum 2007 1.04
47 Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells. Arthritis Rheum 2004 1.04
48 The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens. Arthritis Rheum 2011 1.03
49 Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis. Proc Natl Acad Sci U S A 2004 1.03
50 Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis. Nat Genet 2010 1.00
51 Human CD4+ T cells stimulated by conserved adenovirus 5 hexon peptides recognize cells infected with different species of human adenovirus. Eur J Immunol 2006 0.99
52 The ACPA recognition profile and subgrouping of ACPA-positive RA patients. Ann Rheum Dis 2011 0.98
53 Redefining the HLA and RA association: to be or not to be anti-CCP positive. J Autoimmun 2005 0.96
54 Autoimmunity in rheumatoid arthritis: different antigens--common principles. Ann Rheum Dis 2012 0.95
55 Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis. Ann Rheum Dis 2013 0.95
56 The pathogenic potential of autoreactive antibodies in rheumatoid arthritis. Semin Immunopathol 2014 0.95
57 Macrophages are vital in spontaneous intraocular tumor eradication. Invest Ophthalmol Vis Sci 2006 0.94
58 Antigen presentation by an immature myeloid dendritic cell line does not cause CTL deletion in vivo, but generates CD8+ central memory-like T cells that can be rescued for full effector function. J Immunol 2005 0.93
59 PADI4 polymorphism predisposes male smokers to rheumatoid arthritis. Ann Rheum Dis 2010 0.91
60 Functional killer Ig-like receptors on human memory CD4+ T cells specific for cytomegalovirus. J Immunol 2009 0.91
61 Platelets and autoimmunity. Eur J Clin Invest 2013 0.91
62 T cell avidity determines the level of CTL activation. Eur J Immunol 2004 0.90
63 Immunoglobulin 1 (IgG1) Fc-glycosylation profiling of anti-citrullinated peptide antibodies from human serum. Proteomics Clin Appl 2008 0.89
64 CD4+ T cells are able to promote tumor growth through inhibition of tumor-specific CD8+ T-cell responses in tumor-bearing hosts. Cancer Res 2005 0.89
65 Murine Fc receptors for IgG are redundant in facilitating presentation of immune complex derived antigen to CD8+ T cells in vivo. Mol Immunol 2006 0.88
66 Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis. Ann Rheum Dis 2011 0.87
67 Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with human leukocyte antigen-DRB1 shared epitope alleles. Arthritis Res Ther 2012 0.87
68 Adenovirus-specific CD4+ T cell clones recognizing endogenous antigen inhibit viral replication in vitro through cognate interaction. J Immunol 2006 0.87
69 Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells. Eur J Immunol 2013 0.87
70 Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis. J Autoimmun 2009 0.86
71 Epistasis between two HLA antigens defines a subset of individuals at a very high risk for ankylosing spondylitis. Ann Rheum Dis 2012 0.86
72 Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and major histocompatibility complex-mismatched allogeneic bone marrow transplantation. Blood 2004 0.85
73 Dendritic cells, but not macrophages or B cells, activate major histocompatibility complex class II-restricted CD4+ T cells upon immune-complex uptake in vivo. Immunology 2006 0.85
74 Intraocular tumor antigen drains specifically to submandibular lymph nodes, resulting in an abortive cytotoxic T cell reaction. J Immunol 2004 0.84
75 Adipocyte-derived lipids modulate CD4+ T-cell function. Eur J Immunol 2013 0.83
76 Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells. Blood 2011 0.83
77 A novel role of complement factor C1q in augmenting the presentation of antigen captured in immune complexes to CD8+ T lymphocytes. J Immunol 2007 0.83
78 Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis. Ann Rheum Dis 2013 0.82
79 Genome-wide single-nucleotide polymorphism studies in rheumatology: hype or hope? Arthritis Rheum 2008 0.82
80 Maintenance of immune tolerance depends on normal tissue homeostasis. J Immunol 2005 0.82
81 Communication between human mast cells and CD4(+) T cells through antigen-dependent interactions. Eur J Immunol 2013 0.81
82 Targeting host B-cell immune responses by persistent donor NK-cell alloreactivity following nonmyeloablative allogeneic stem cell transplantation. Blood 2007 0.81
83 Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis. Ann Rheum Dis 2009 0.81
84 HLA and RA revisited: citrullinated food for the SE hypothesis, the DR6 effect, and NIMA. Hum Immunol 2006 0.81
85 Are baseline high molecular weight adiponectin levels associated with radiographic progression in rheumatoid arthritis and osteoarthritis? J Rheumatol 2014 0.80
86 CD25+ regulatory cells from HLA-DQ8 transgenic mice are capable of modulating collagen-induced arthritis. Hum Immunol 2004 0.79
87 High dose chemotherapy and autologous hematopoietic stem cell transplantation for rheumatoid arthritis: a review. Hum Immunol 2002 0.79
88 IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation. Eur J Immunol 2014 0.79
89 DX5(+)CD4(+) T cells modulate cytokine production by CD4(+) T cells towards IL-10 via the production of IL-4. Eur J Immunol 2010 0.78
90 Decreased serum cell-free DNA levels in rheumatoid arthritis. Auto Immun Highlights 2015 0.78
91 Fine-mapping the human leukocyte antigen locus in rheumatoid arthritis and other rheumatic diseases: identifying causal amino acid variants? Curr Opin Rheumatol 2015 0.77
92 DC-induced CD8(+) T-cell response is inhibited by MHC class II-dependent DX5(+)CD4(+) Treg. Eur J Immunol 2009 0.77
93 Mesenchymal stem cells in autoimmune diseases: hype or hope? Arthritis Res Ther 2010 0.77
94 The role of anticitrullinated protein antibodies in the early stages of rheumatoid arthritis. Curr Opin Rheumatol 2016 0.76
95 Bridging autoantibodies and arthritis: the role of Fc receptors. Curr Top Microbiol Immunol 2014 0.75
96 Anticytomegalovirus seropositivity in rheumatoid arthritis is not associated with the presence of severe extraarticular complications: comment on the article by Pierer et al. Arthritis Rheum 2012 0.75
97 Fibroblast-like synoviocytes from rheumatoid arthritis patients express less FLICE-inhibitory protein than fibroblast-like synoviocytes from trauma patients: comment on the article by Schedel et al. Arthritis Rheum 2003 0.75
98 HLA-B60 and the HLA-B27/HLA-B60 genotype are not risk factors for acute anterior uveitis. Ann Rheum Dis 2013 0.75
99 Persisting NK cell alloreactivity in the presence of long-term stable hematopoietic chimerism. Exp Hematol 2009 0.75
100 DX5+ CD4+ T cells modulate CD4+ T-cell response via inhibition of IL-12 production by DCs. Eur J Immunol 2013 0.75
101 The contribution of autoantibodies to post-translationally modified proteins to inflammatory arthritis. Curr Opin Rheumatol 2016 0.75