PubRank

Luciano Rossetti

Author PubWeight™ 109.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 2008 4.89
2 Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver. Cell Metab 2007 4.74
3 Hypothalamic insulin signaling is required for inhibition of glucose production. Nat Med 2002 4.69
4 Hypothalamic K(ATP) channels control hepatic glucose production. Nature 2005 4.56
5 Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J Biol Chem 2005 4.32
6 Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats. Nat Neurosci 2002 3.64
7 Regulation of fasted blood glucose by resistin. Science 2004 3.54
8 Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake. Nat Med 2006 3.24
9 Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production. Nat Med 2003 3.21
10 Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production. J Clin Invest 2003 3.11
11 A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology 2003 3.04
12 Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest 2003 2.95
13 Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms. Nat Med 2008 2.91
14 Central administration of oleic acid inhibits glucose production and food intake. Diabetes 2002 2.91
15 Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? Diabetes 2002 2.90
16 A brain-liver circuit regulates glucose homeostasis. Cell Metab 2005 2.83
17 Hypothalamic sensing of fatty acids. Nat Neurosci 2005 2.67
18 Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis. Nat Med 2005 2.66
19 Regulation of blood glucose by hypothalamic pyruvate metabolism. Science 2005 2.28
20 Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance. J Clin Invest 2006 2.13
21 Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats. J Clin Invest 2006 1.94
22 Molecular disruption of hypothalamic nutrient sensing induces obesity. Nat Neurosci 2006 1.87
23 Role of resistin in diet-induced hepatic insulin resistance. J Clin Invest 2004 1.83
24 Disulfide-dependent multimeric assembly of resistin family hormones. Science 2004 1.76
25 Critical role of STAT3 in leptin's metabolic actions. Cell Metab 2006 1.70
26 The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis. Mol Cell Biol 2009 1.69
27 Central leptin acutely reverses diet-induced hepatic insulin resistance. Diabetes 2005 1.69
28 Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action. J Clin Invest 2005 1.55
29 Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats. J Clin Invest 2008 1.53
30 Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins. Nat Med 2007 1.51
31 Minireview: nutrient sensing and the regulation of insulin action and energy balance. Endocrinology 2003 1.47
32 Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons. Diabetes 2009 1.46
33 Hypothalamic responses to long-chain fatty acids are nutritionally regulated. J Biol Chem 2004 1.44
34 Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice. Diabetes 2007 1.42
35 Abnormal glucose homeostasis due to chronic hyperresistinemia. Diabetes 2004 1.39
36 Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice. J Clin Invest 2005 1.35
37 Melanocortin-independent effects of leptin on hepatic glucose fluxes. J Biol Chem 2004 1.35
38 Identification of a biochemical link between energy intake and energy expenditure. J Clin Invest 2002 1.29
39 Fructose improves the ability of hyperglycemia per se to regulate glucose production in type 2 diabetes. Diabetes 2002 1.13
40 Identification and characterization of a novel phosphorylation site on the GluR1 subunit of AMPA receptors. Mol Cell Neurosci 2007 1.12
41 Leptin resistance during aging is independent of fat mass. Diabetes 2002 1.12
42 Hypothalamic resistin induces hepatic insulin resistance. J Clin Invest 2007 1.10
43 Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2. FASEB J 2008 1.08
44 Hypothalamic protein kinase C regulates glucose production. Diabetes 2008 1.07
45 Role of transcription factor NFAT in glucose and insulin homeostasis. Mol Cell Biol 2006 1.02
46 Glycemic control determines hepatic and peripheral glucose effectiveness in type 2 diabetic subjects. Diabetes 2002 0.98
47 Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats. Diabetes 2011 0.98
48 Intracerebroventricular leptin regulates hepatic cholesterol metabolism. Biochem J 2004 0.96
49 Hyperglycemia induces PAI-1 gene expression in adipose tissue by activation of the hexosamine biosynthetic pathway. Atherosclerosis 2002 0.91
50 Fructose amplifies counterregulatory responses to hypoglycemia in humans. Diabetes 2002 0.86
51 Hypothalamic sensing of circulating lactate regulates glucose production. J Cell Mol Med 2010 0.84
52 Effects of fasting and glucocorticoids on hepatic gluconeogenesis assessed using two independent methods in vivo. Am J Physiol Endocrinol Metab 2002 0.83
53 Einstein's Institute for Aging Research: collaborative and programmatic approaches in the search for successful aging. Exp Gerontol 2004 0.81
54 A new piece in the diabetes puzzle. Nat Med 2002 0.77
55 Did a muscle fuel gauge conquer the brain? Nat Med 2006 0.76
56 An audience with Luciano Rossetti. Interview by Bethan Hughes. Nat Rev Drug Discov 2010 0.75
57 Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes 2017 0.75
58 Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700. Diabetes 2017 0.75