PubRank

Elizabeth H Blackburn

Author PubWeight™ 123.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A 2004 12.89
2 The telomere syndromes. Nat Rev Genet 2012 4.01
3 Telomere length is paternally inherited and is associated with parental lifespan. Proc Natl Acad Sci U S A 2007 3.67
4 Increased telomerase activity and comprehensive lifestyle changes: a pilot study. Lancet Oncol 2008 3.57
5 Telomeres and telomerase. Philos Trans R Soc Lond B Biol Sci 2004 3.13
6 Cell aging in relation to stress arousal and cardiovascular disease risk factors. Psychoneuroendocrinology 2005 3.08
7 Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol Cell 2003 2.78
8 New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Oncogene 2002 2.46
9 The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men. Aging (Albany NY) 2008 2.35
10 Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress--preliminary findings. PLoS One 2011 2.30
11 DNA damage signalling prevents deleterious telomere addition at DNA breaks. Nat Cell Biol 2009 2.05
12 A bulged stem tethers Est1p to telomerase RNA in budding yeast. Genes Dev 2002 1.95
13 Association between telomere length, specific causes of death, and years of healthy life in health, aging, and body composition, a population-based cohort study. J Gerontol A Biol Sci Med Sci 2009 1.90
14 Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci U S A 2011 1.88
15 A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein. Proc Natl Acad Sci U S A 2004 1.83
16 Socioeconomic status, health behavior, and leukocyte telomere length in the National Health and Nutrition Examination Survey, 1999-2002. Soc Sci Med 2013 1.81
17 A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A 2002 1.79
18 Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. PLoS One 2011 1.78
19 Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology 2010 1.73
20 Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression. Cell 2009 1.72
21 Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA 2010 1.71
22 Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules. J Cell Biol 2004 1.71
23 Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Mol Cell Biol 2004 1.69
24 Dynamics of telomerase activity in response to acute psychological stress. Brain Behav Immun 2009 1.68
25 Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA. Cancer Res 2004 1.66
26 Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length. Mol Cell Biol 2004 1.66
27 Human cancer cells harbor T-stumps, a distinct class of extremely short telomeres. Mol Cell 2007 1.56
28 A novel pseudoknot element is essential for the action of a yeast telomerase. Genes Dev 2003 1.55
29 Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study. Lancet Oncol 2013 1.55
30 Comprehensive structure-function analysis of the core domain of human telomerase RNA. Mol Cell Biol 2003 1.49
31 Visualization of actin filaments and monomers in somatic cell nuclei. Mol Biol Cell 2013 1.40
32 Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita. Blood 2005 1.37
33 Socioeconomic status and cell aging in children. Soc Sci Med 2012 1.32
34 Genes and pathways downstream of telomerase in melanoma metastasis. Proc Natl Acad Sci U S A 2006 1.27
35 The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 2002 1.27
36 Shorter leukocyte telomere length in midlife women with poor sleep quality. J Aging Res 2011 1.26
37 Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA. J Biol Chem 2005 1.25
38 A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity. RNA 2003 1.24
39 Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere length. Brain Behav Immun 2012 1.22
40 Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA. Genes Dev 2004 1.21
41 A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase. Genes Dev 2003 1.20
42 Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length. Am J Obstet Gynecol 2012 1.16
43 Telomere shortening in formerly abused and never abused women. Biol Res Nurs 2011 1.15
44 Rapid telomere motions in live human cells analyzed by highly time-resolved microscopy. Epigenetics Chromatin 2008 1.13
45 Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break. Genes Dev 2008 1.12
46 Soda and cell aging: associations between sugar-sweetened beverage consumption and leukocyte telomere length in healthy adults from the National Health and Nutrition Examination Surveys. Am J Public Health 2014 1.10
47 Tracking telomerase. Cell 2004 1.10
48 The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis. Cancer Res 2013 1.04
49 Catalytically active human telomerase mutants with allele-specific biological properties. Exp Cell Res 2003 1.02
50 Processive utilization of the human telomerase template: lack of a requirement for template switching. J Biol Chem 2004 1.01
51 Telomerase core components protect Candida telomeres from aberrant overhang accumulation. Proc Natl Acad Sci U S A 2007 1.01
52 Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002. Epidemiology 2015 1.00
53 ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells. Cancer Res 2008 0.99
54 Hostility and cellular aging in men from the Whitehall II cohort. Biol Psychiatry 2011 0.99
55 Chronic stress elevates telomerase activity in rats. Biol Lett 2012 0.98
56 Accelerated cell aging in female APOE-ε4 carriers: implications for hormone therapy use. PLoS One 2013 0.98
57 Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response. Mol Biol Cell 2004 0.97
58 Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA. Clin Cancer Res 2004 0.97
59 Shorter telomeres with high telomerase activity are associated with raised allostatic load and impoverished psychosocial resources. Proc Natl Acad Sci U S A 2014 0.97
60 A common variant in the telomerase RNA component is associated with short telomere length. PLoS One 2010 0.95
61 Dynamics of telomeric DNA turnover in yeast. Genetics 2002 0.95
62 Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells. Cancer Res 2006 0.94
63 Longer leukocyte telomere length in Costa Rica's Nicoya Peninsula: a population-based study. Exp Gerontol 2013 0.93
64 Associations of cadmium and lead exposure with leukocyte telomere length: findings from National Health and Nutrition Examination Survey, 1999-2002. Am J Epidemiol 2014 0.91
65 An investigation of the effects of the core protein telomerase reverse transcriptase on Wnt signaling in breast cancer cells. Mol Cell Biol 2013 0.90
66 The telotype defines the telomere state in Saccharomyces cerevisiae and is inherited as a dominant non-Mendelian characteristic in cells lacking telomerase. Genetics 2008 0.88
67 A novel Tel1/ATM N-terminal motif, TAN, is essential for telomere length maintenance and a DNA damage response. Mol Cell Biol 2008 0.88
68 Multisystem resiliency moderates the major depression-telomere length association: findings from the Heart and Soul Study. Brain Behav Immun 2013 0.87
69 Unprecedented opportunities and promise for cancer prevention research. Cancer Prev Res (Phila) 2010 0.86
70 The terminal telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion. Mol Cell 2010 0.86
71 Characterization of the yeast telomere nucleoprotein core: Rap1 binds independently to each recognition site. J Biol Chem 2010 0.86
72 Maternal estriol concentrations in early gestation predict infant telomere length. J Clin Endocrinol Metab 2015 0.85
73 Cytomegalovirus is associated with reduced telomerase activity in the Whitehall II cohort. Exp Gerontol 2013 0.85
74 Maternal Folate Concentration in Early Pregnancy and Newborn Telomere Length. Ann Nutr Metab 2015 0.85
75 Highlighting the science of cancer prevention. Cancer Prev Res (Phila) 2010 0.82
76 Seasonal variation of peripheral blood leukocyte telomere length in Costa Rica: A population-based observational study. Am J Hum Biol 2014 0.81
77 Mec1 function in the DNA damage response does not require its interaction with Tel2. Cell Cycle 2008 0.81
78 Movement-Based Behaviors and Leukocyte Telomere Length among US Adults. Med Sci Sports Exerc 2015 0.77
79 Cell biology: Shaggy mouse tales. Nature 2005 0.77
80 A Trypanosoma brucei protein complex that binds G-overhangs and co-purifies with telomerase activity. J Biol Chem 2001 0.76
81 Correction: Change in Leukocyte Telomere Length Predicts Mortality in Patients with Stable Coronary Heart Disease from the Heart and Soul Study. PLoS One 2016 0.75
82 Actuary of the cell. Interview by Thea Singer. Sci Am 2011 0.75