Published in J Cereb Blood Flow Metab on May 01, 2003
Neuroprotection for ischemic stroke: past, present and future. Neuropharmacology (2008) 3.04
Neuroprotective mechanisms of hypothermia in brain ischaemia. Nat Rev Neurosci (2012) 2.02
Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med (2009) 1.70
State of the art in therapeutic hypothermia. Annu Rev Med (2011) 1.45
Diagnosis influences response of cerebral near infrared spectroscopy to intracranial hypertension in children. Pediatr Crit Care Med (2010) 1.43
Hypothermic neuroprotection. NeuroRx (2006) 1.36
Metabolic downregulation: a key to successful neuroprotection? Stroke (2008) 1.33
Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia. Neurobiol Dis (2008) 1.24
A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice. FASEB J (2012) 1.11
Hypothermia in bleeding trauma: a friend or a foe? Scand J Trauma Resusc Emerg Med (2009) 1.11
Deep hypothermic circulatory arrest. Ann Cardiothorac Surg (2013) 1.01
Cerebral oxygen metabolism in neonatal hypoxic ischemic encephalopathy during and after therapeutic hypothermia. J Cereb Blood Flow Metab (2013) 0.99
Investigational therapies for ischemic stroke: neuroprotection and neurorecovery. Neurotherapeutics (2011) 0.98
Long-duration perforated patch recordings from spinal interneurons of adult mice. J Neurophysiol (2011) 0.97
Advanced In Vivo Heteronuclear MRS Approaches for Studying Brain Bioenergetics Driven by Mitochondria. Methods Mol Biol (2009) 0.95
Brain cell death is reduced with cooling by 3.5°C to 5°C but increased with cooling by 8.5°C in a piglet asphyxia model. Stroke (2014) 0.93
Therapeutic hypothermia for neuroprotection: history, mechanisms, risks, and clinical applications. Neurohospitalist (2014) 0.93
Hypothermia after acute ischemic stroke. J Neurotrauma (2009) 0.91
Therapeutic effects of pharmacologically induced hypothermia against traumatic brain injury in mice. J Neurotrauma (2014) 0.89
Post-stroke hypothermia provides neuroprotection through inhibition of AMP-activated protein kinase. J Neurotrauma (2011) 0.87
In vivo oxygen-17 NMR for imaging brain oxygen metabolism at high field. Prog Nucl Magn Reson Spectrosc (2011) 0.87
Therapeutic hypothermia as a neuroprotective strategy in neonatal hypoxic-ischemic brain injury and traumatic brain injury. Curr Mol Med (2012) 0.86
Non-pharmaceutical therapies for stroke: mechanisms and clinical implications. Prog Neurobiol (2014) 0.86
Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection. J Bioenerg Biomembr (2014) 0.85
Drug-induced hypothermia in stroke models: does it always protect? CNS Neurol Disord Drug Targets (2013) 0.83
Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats. Am J Physiol Endocrinol Metab (2013) 0.83
Adhesion formation after laparoscopic surgery: what do we know about the role of the peritoneal environment? Facts Views Vis Obgyn (2010) 0.83
The Use of Hypothermia Therapy in Traumatic Ischemic / Reperfusional Brain Injury: Review of the Literatures. Ther Hypothermia Temp Manag (2011) 0.82
Neuroprotective effect of preoperatively induced mild hypothermia as determined by biomarkers and histopathological estimation in a rat subdural hematoma decompression model. J Neurosurg (2012) 0.82
Prevention of hypoglycemia-induced neuronal death by hypothermia. J Cereb Blood Flow Metab (2009) 0.81
Maximizing neuroprotection: where do we stand? Ther Clin Risk Manag (2012) 0.80
Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway. J Transl Med (2014) 0.80
Constancy and trade-offs in the neuroanatomical and metabolic design of the cerebral cortex. Front Neural Circuits (2014) 0.80
Hypothermia protects human neurons. Int J Stroke (2014) 0.79
The effects of therapeutic hypothermia on cerebral metabolism in neonates with hypoxic-ischemic encephalopathy: An in vivo 1H-MR spectroscopy study. J Cereb Blood Flow Metab (2015) 0.78
Oxidative stress and antioxidant activity in hypothermia and rewarming: can RONS modulate the beneficial effects of therapeutic hypothermia? Oxid Med Cell Longev (2013) 0.78
The brain is hypothermic in patients with mitochondrial diseases. J Cereb Blood Flow Metab (2014) 0.78
Therapeutic hypothermia for refractory status epilepticus in a child with malignant migrating partial seizures of infancy and SCN1A mutation: a case report. Ther Hypothermia Temp Manag (2012) 0.78
Nanotechnology Approaches to Targeting Inflammation and Excitotoxicity in a Canine Model of Hypothermic Circulatory Arrest-Induced Brain Injury. Ann Thorac Surg (2016) 0.78
Fundamental research progress of mild hypothermia in cerebral protection. Springerplus (2013) 0.77
Use of hypothermia in the intensive care unit. World J Crit Care Med (2012) 0.77
Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death. PLoS One (2013) 0.77
Proton resonance frequency chemical shift thermometry: experimental design and validation toward high-resolution noninvasive temperature monitoring and in vivo experience in a nonhuman primate model of acute ischemic stroke. AJNR Am J Neuroradiol (2015) 0.76
Hydrogen sulphide and mild hypothermia activate the CREB signaling pathway and prevent ischemia-reperfusion injury. BMC Anesthesiol (2015) 0.76
Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery. Arch Gynecol Obstet (2015) 0.75
Stress does not increase blood-brain barrier permeability in mice. J Cereb Blood Flow Metab (2016) 0.75
Delayed and prolonged local brain hypothermia combined with decompressive craniectomy: a novel therapeutic strategy that modulates glial dynamics. Exp Neurobiol (2014) 0.75
A new approach to selective brain cooling by a Ranque-Hilsch vortex tube. Intensive Care Med Exp (2016) 0.75
Targeted temperature management in traumatic brain injury. J Intensive Care (2016) 0.75
Targeted temperature management: Current evidence and practices in critical care. Indian J Crit Care Med (2015) 0.75
Hypothermia reduces VEGF-165 expression, but not osteogenic differentiation of human adipose stem cells under hypoxia. PLoS One (2017) 0.75
Therapeutic hypothermia for acute neurological injuries. Neurotherapeutics (2012) 0.75
Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System. Oxid Med Cell Longev (2016) 0.75
Hypothermia during Carotid Endarterectomy: A Safety Study. PLoS One (2016) 0.75
Coupling of cerebral blood flow and oxygen consumption during hypothermia in newborn piglets as measured by time-resolved near-infrared spectroscopy: a pilot study. Neurophotonics (2015) 0.75
Targeted temperature management in neurological intensive care unit. World J Methodol (2017) 0.75
Mild hypothermia protects against oxygen glucose deprivation (OGD)-induced cell death in brain slices from adult mice. J Neural Transm (Vienna) (2013) 0.75
Longitudinal MRI evaluation of neuroprotective effects of pharmacologically induced hypothermia in experimental ischemic stroke. Magn Reson Imaging (2017) 0.75
Effect of temperature on FAD and NADH-derived signals and neurometabolic coupling in the mouse auditory and motor cortex. Pflugers Arch (2017) 0.75
Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet (2005) 11.41
Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med (2009) 7.94
Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial. Lancet Neurol (2009) 2.96
Determinants of outcomes after head cooling for neonatal encephalopathy. Pediatrics (2007) 2.64
Effects of hypothermia for perinatal asphyxia on childhood outcomes. N Engl J Med (2014) 2.41
Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy. Pediatrics (2005) 2.26
Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop. J Pediatr (2011) 2.22
The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial. BMC Pediatr (2008) 1.91
Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop. J Pediatr (2006) 1.67
Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs. Ann Neurol (2010) 1.65
Comparison of Bayley-2 and Bayley-3 scores at 18 months in term infants following neonatal encephalopathy and therapeutic hypothermia. Dev Med Child Neurol (2013) 1.56
Energy metabolism in mammalian brain during development. Prog Neurobiol (2004) 1.54
Serum gentamicin concentrations in encephalopathic infants are not affected by therapeutic hypothermia. Pediatrics (2009) 1.51
Therapeutic hypothermia changes the prognostic value of clinical evaluation of neonatal encephalopathy. J Pediatr (2007) 1.50
Neonatal seizures: magnetic resonance imaging adds value in the diagnosis and prediction of neurodisability. Acta Paediatr (2014) 1.40
Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia. Resuscitation (2013) 1.37
Seven- to eight-year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy. Pediatr Res (2011) 1.21
Therapeutic hypothermia in neonates. Review of current clinical data, ILCOR recommendations and suggestions for implementation in neonatal intensive care units. Resuscitation (2008) 1.20
Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia. Stroke (2005) 1.19
Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective. Ann Neurol (2003) 1.17
Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia. Stroke (2008) 1.15
The pathogenesis of neonatal post-hemorrhagic hydrocephalus. Brain Pathol (2004) 1.06
Immediate hypothermia is not neuroprotective after severe hypoxia-ischemia and is deleterious when delayed by 12 hours in neonatal rats. Stroke (2012) 1.04
Hypothermia: an evolving treatment for neonatal hypoxic ischemic encephalopathy. Pediatrics (2008) 1.01
A neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation. J Neurosurg (2007) 0.95
A closed-circuit neonatal xenon delivery system: a technical and practical neuroprotection feasibility study in newborn pigs. Anesth Analg (2009) 0.94
A comparison of cooling methods used in therapeutic hypothermia for perinatal asphyxia. Pediatrics (2010) 0.94
Posthemorrhagic ventricular dilation in the neonate: development and characterization of a rat model. J Neuropathol Exp Neurol (2003) 0.91
Randomized clinical trial of prevention of hydrocephalus after intraventricular hemorrhage in preterm infants: brain-washing versus tapping fluid. Pediatrics (2007) 0.90
Analysis of neuronal, glial, endothelial, axonal and apoptotic markers following moderate therapeutic hypothermia and anesthesia in the developing piglet brain. Brain Pathol (2007) 0.89
Factors associated with permanent hearing impairment in infants treated with therapeutic hypothermia. J Pediatr (2013) 0.88
Development of amplitude-integrated electroencephalography and interburst interval in the rat. Pediatr Res (2009) 0.88
Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury. Pediatr Res (2012) 0.87
Significant selective head cooling can be maintained long-term after global hypoxia ischemia in newborn piglets. Pediatrics (2002) 0.86
Delayed hypothermia as selective head cooling or whole body cooling does not protect brain or body in newborn pig subjected to hypoxia-ischemia. Pediatr Res (2008) 0.86
Phase 1 trial of prevention of hydrocephalus after intraventricular hemorrhage in newborn infants by drainage, irrigation, and fibrinolytic therapy. Pediatrics (2003) 0.85
Response of a collagenase-induced tendon injury to treatment with a polysulphated glycosaminoglycan (Adequan). Connect Tissue Res (2008) 0.85
Do drugs that block transforming growth factor beta reduce posthaemorrhagic ventricular dilatation in a neonatal rat model? Acta Paediatr (2008) 0.85
Translational stroke research in the developing brain. Pediatr Neurol (2006) 0.84
Cerebral Resistance Index is less predictive in hypothermic encephalopathic newborns. Acta Paediatr (2011) 0.84
Neither xenon nor fentanyl induces neuroapoptosis in the newborn pig brain. Anesthesiology (2013) 0.84
Xenon offers stable haemodynamics independent of induced hypothermia after hypoxia-ischaemia in newborn pigs. Intensive Care Med (2011) 0.83
Clinical trials of treatments after perinatal asphyxia. Curr Opin Pediatr (2002) 0.83
Does head cooling with mild systemic hypothermia affect requirement for blood pressure support? Pediatrics (2009) 0.83
Non-protein-bound iron in brain interstitium of newborn pigs after hypoxia. Dev Neurosci (2005) 0.82
Preliminary evaluation of a novel intraparenchymal capacitive intracranial pressure monitor. J Neurosurg (2011) 0.81
Resuscitation with 100% oxygen increases injury and counteracts the neuroprotective effect of therapeutic hypothermia in the neonatal rat. Pediatr Res (2012) 0.80
Lactate dehydrogenase predicts hypoxic ischaemic encephalopathy in newborn infants: a preliminary study. Acta Paediatr (2010) 0.80
Immediate hypothermia reduces cardiac troponin I after hypoxic-ischemic encephalopathy in newborn pigs. Pediatr Res (2011) 0.79
Effects of a serotonin S2-receptor blocker on healing of acute and chronic tendon injuries. J Invest Surg (2009) 0.79
Effects of xenon and hypothermia on cerebrovascular pressure reactivity in newborn global hypoxic-ischemic pig model. J Cereb Blood Flow Metab (2013) 0.78
Decorin and colchicine as potential treatments for post-haemorrhagic ventricular dilatation in a neonatal rat model. Neonatology (2011) 0.78
Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury. Dev Neurosci (2015) 0.78
Respiratory sinus arrhythmia stabilizes mean arterial blood pressure at high-frequency interval in healthy humans. Eur J Appl Physiol (2014) 0.77
Early deterioration of cerebrospinal fluid dynamics in a neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation. J Neurosurg Pediatr (2012) 0.77
Metrenperone enhances collagen turnover and remodeling in the early stages of healing of tendon injury in rabbit. Arch Orthop Trauma Surg (2010) 0.77
Xenon/hypothermia neuroprotection regimes in spontaneously breathing neonatal rats after hypoxic-ischemic insult: the respiratory and sedative effects. Anesth Analg (2008) 0.77
Cooling neonates who do not fulfil the standard cooling criteria - short- and long-term outcomes. Acta Paediatr (2014) 0.76
The feasibility of using a portable xenon delivery device to permit earlier xenon ventilation with therapeutic cooling of neonates during ambulance retrieval. Anesth Analg (2015) 0.76
Novel application of a tissue-engineered collagen-based three-dimensional bio-implant in a large tendon defect model: a broad-based study with high value in translational medicine. Tissue Cell (2013) 0.76
Liver enzymes cannot be used to predict liver damage after global hypoxia-ischemia in a neonatal pig model. Neonatology (2009) 0.76
Increased inspired oxygen in the first hours of life is associated with adverse outcome in newborns treated for perinatal asphyxia with therapeutic hypothermia. J Pediatr (2012) 0.76
Experimental Validation of Methods for Prophylaxis against Deep Venous Thrombosis: A Review and Proposal. Thrombosis (2012) 0.75
Environmental cooling of the newborn pig brain during whole-body cooling. Acta Paediatr (2011) 0.75
Brain wave recovery predicts outcome after cardiac arrest. Resuscitation (2012) 0.75
Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent. Dev Neurosci (2017) 0.75
Equipotent subanesthetic concentrations of sevoflurane and xenon preventing cold-stimulated vocalization of neonatal rats. Anesthesiology (2014) 0.75