Published in J Neurophysiol on June 18, 2003
Descending control of nociception: Specificity, recruitment and plasticity. Brain Res Rev (2008) 2.75
Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br J Pharmacol (2007) 1.28
Unravelling the mystery of capsaicin: a tool to understand and treat pain. Pharmacol Rev (2012) 1.25
Hot receptors in the brain. Mol Pain (2006) 1.09
Moving towards supraspinal TRPV1 receptors for chronic pain relief. Mol Pain (2010) 0.99
Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. Br J Pharmacol (2011) 0.97
TRPV1: a target for next generation analgesics. Curr Neuropharmacol (2008) 0.95
Antiaversive effects of cannabinoids: is the periaqueductal gray involved? Neural Plast (2008) 0.91
Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway. Neurosci Lett (2012) 0.88
Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey. J Physiol (2009) 0.88
Opposing roles for cannabinoid receptor type-1 (CB₁) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats. Neuropsychopharmacology (2011) 0.87
Prostaglandin E2 (PGE2) inhibits glutamatergic synaptic transmission in dorsolateral periaqueductal gray (dl-PAG). Brain Res (2007) 0.84
Are opioid-sensitive neurons in the rostral ventromedial medulla inhibitory interneurons? Neuroscience (2007) 0.83
Purinergic P2X receptors presynaptically increase glutamatergic synaptic transmission in dorsolateral periaqueductal gray. Brain Res (2008) 0.77
Role of angiotensin-(1-7) and Mas-R-nNOS pathways in amplified neuronal activity of dorsolateral periaqueductal gray after chronic heart failure. Neurosci Lett (2014) 0.76
Emerging Role of Spinal Cord TRPV1 in Pain Exacerbation. Neural Plast (2016) 0.76
Divergent Modulation of Nociception by Glutamatergic and GABAergic Neuronal Subpopulations in the Periaqueductal Gray. eNeuro (2017) 0.75
Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. Psychopharmacology (Berl) (2012) 0.75
TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats. J Neurophysiol (2017) 0.75
Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease. J Neurochem (2005) 3.06
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A (2007) 2.60
A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proc Natl Acad Sci U S A (2002) 2.24
A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat. J Pharmacol Exp Ther (2006) 2.06
Purine and pyrimidine (P2) receptors as drug targets. J Med Chem (2002) 2.05
Upregulation of SATB1 promotes tumor growth and metastasis in liver cancer. Liver Int (2012) 2.02
Presenilin 1 is required for maturation and cell surface accumulation of nicastrin. J Biol Chem (2002) 1.61
A marked decrease in L-selectin expression by leucocytes in infants with Bordetella pertussis infection: leucocytosis explained? Respirology (2003) 1.59
Phosphodiesterase-5 inhibitors for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a systematic review and meta-analysis. Urology (2011) 1.56
Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states. Pain (2006) 1.55
P2X receptors as drug targets. Mol Pharmacol (2012) 1.43
Molecular determinants of species-specific activation or blockade of TRPA1 channels. J Neurosci (2008) 1.42
Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration. Br J Pharmacol (2003) 1.42
Properties of urethral rhabdosphincter motoneurons and their regulation by noradrenaline. J Physiol (2010) 1.40
Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors. Br J Pharmacol (2009) 1.39
Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X7 antagonists. J Med Chem (2006) 1.36
Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation. Pain (2011) 1.34
Pore dilation occurs in TRPA1 but not in TRPM8 channels. Mol Pain (2009) 1.34
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. J Pharmacol Exp Ther (2005) 1.33
Painful purinergic receptors. J Pharmacol Exp Ther (2007) 1.33
Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways. J Neurosci (2007) 1.32
Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats. Pain (2002) 1.27
Interleukin-1alphabeta gene-deficient mice show reduced nociceptive sensitivity in models of inflammatory and neuropathic pain but not post-operative pain. Behav Brain Res (2005) 1.25
Localization of histamine H4 receptors in the central nervous system of human and rat. Brain Res (2008) 1.24
Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors. Curr Top Med Chem (2005) 1.24
Transient receptor potential A1 mediates an osmotically activated ion channel. Eur J Neurosci (2008) 1.23
TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Mol Pain (2010) 1.22
Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells. J Pharmacol Exp Ther (2003) 1.21
Multivariate and geostatistical analyses of the spatial distribution and origin of heavy metals in the agricultural soils in Shunyi, Beijing, China. Sci Total Environ (2012) 1.19
Altered expression profiles of microRNAs in a stable hepatitis B virus-expressing cell line. Chin Med J (Engl) (2009) 1.16
Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo. Diabetes (2007) 1.15
Functional expression of P2X7 receptors in non-neuronal cells of rat dorsal root ganglia. Brain Res (2005) 1.14
Child sexual abuse in Henan province, China: associations with sadness, suicidality, and risk behaviors among adolescent girls. J Adolesc Health (2006) 1.12
Role of tramadol in premature ejaculation: a systematic review and meta-analysis. Urol Int (2013) 1.12
Identification of (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea (ABT-102) as a potent TRPV1 antagonist for pain management. J Med Chem (2008) 1.10
Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment. Brain Res Rev (2008) 1.08
The efficacy and safety of tubeless percutaneous nephrolithotomy: a systematic review and meta-analysis. Urol Res (2011) 1.08
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics. Pain (2002) 1.08
Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders. Behav Brain Res (2008) 1.06
TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells. J Neurochem (2006) 1.05
Clinical features and spiral computed tomography analysis of undifferentiated embryonic liver sarcoma in adults. J Dig Dis (2009) 1.05
Child sexual abuse in China: a study of adolescents in four provinces. Child Abuse Negl (2004) 1.03
Enhanced thermal avoidance in mice lacking the ATP receptor P2X3. Pain (2005) 1.02
Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: potential therapeutic use in the treatment of inflammatory bowel disease. Cytometry (2002) 1.02
Differential action potentials and firing patterns in injured and uninjured small dorsal root ganglion neurons after nerve injury. Brain Res (2004) 1.02
Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat. Exp Brain Res (2002) 1.01
Liraglutide for the treatment of type 2 diabetes mellitus: a meta-analysis of randomized placebo-controlled trials. Adv Ther (2014) 1.00
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel and selective transient receptor potential type V1 receptor antagonist, blocks channel activation by vanilloids, heat, and acid. J Pharmacol Exp Ther (2005) 0.99
Lixisenatide treatment improves glycaemic control in Asian patients with type 2 diabetes mellitus inadequately controlled on metformin with or without sulfonylurea: a randomized, double-blind, placebo-controlled, 24-week trial (GetGoal-M-Asia). Diabetes Metab Res Rev (2014) 0.99
The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1alphabeta knockout mice. Behav Brain Res (2009) 0.99
Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha4beta2 subunit combination. Biochem Pharmacol (2009) 0.99
Multislice spiral computed tomography imaging in congenital inner ear malformations. J Comput Assist Tomogr (2008) 0.98
In vivo pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107: preclinical considerations in Alzheimer's disease. J Pharmacol Exp Ther (2010) 0.98
A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats. J Pharmacol Exp Ther (2007) 0.97
5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel inhibitors of adenosine kinase. J Med Chem (2003) 0.97
Upregulation of long noncoding RNA SPRY4-IT1 modulates proliferation, migration, apoptosis, and network formation in trophoblast cells HTR-8SV/neo. PLoS One (2013) 0.97
Selective P2X(7) receptor antagonists for chronic inflammation and pain. Purinergic Signal (2008) 0.97
Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats. J Neurophysiol (2005) 0.96
Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain (2011) 0.96
Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties. CNS Neurosci Ther (2008) 0.96
Id-1 and the p65 subunit of NF-κB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis. Carcinogenesis (2012) 0.96
Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats. J Neurophysiol (2008) 0.96
Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. Mol Pain (2011) 0.95
Antisense knockdown of the rat alpha7 nicotinic acetylcholine receptor produces spatial memory impairment. Neurosci Lett (2006) 0.94
The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons. Neurochem Int (2008) 0.93