Published in Mol Microbiol on July 01, 2003
Bacterial virulence in the moonlight: multitasking bacterial moonlighting proteins are virulence determinants in infectious disease. Infect Immun (2011) 1.99
Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pneumoniae is a surface-displayed plasminogen-binding protein. Infect Immun (2004) 1.74
PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun (2005) 1.54
Proteomic analysis and identification of Streptococcus pyogenes surface-associated proteins. J Bacteriol (2006) 1.39
Role of the C-terminal lysine residues of streptococcal surface enolase in Glu- and Lys-plasminogen-binding activities of group A streptococci. Infect Immun (2004) 1.19
Lactic acid bacteria contribution to gut microbiota complexity: lights and shadows. Front Cell Infect Microbiol (2012) 1.18
Borrelia burgdorferi adhesins identified using in vivo phage display. Mol Microbiol (2007) 1.17
Defining the structural basis of human plasminogen binding by streptococcal surface enolase. J Biol Chem (2009) 1.12
Comparative genomic analysis of the Streptococcus dysgalactiae species group: gene content, molecular adaptation, and promoter evolution. Genome Biol Evol (2011) 1.11
Cytosolic proteins contribute to surface plasminogen recruitment of Neisseria meningitidis. J Bacteriol (2007) 1.10
Alpha-enolase resides on the cell surface of Mycoplasma fermentans and binds plasminogen. Infect Immun (2007) 1.07
Enolase as a plasminogen binding protein in Leishmania mexicana. Parasitol Res (2007) 1.05
Streptococcus pneumoniae choline-binding protein E interaction with plasminogen/plasmin stimulates migration across the extracellular matrix. Infect Immun (2007) 1.04
Surface-expressed enolase contributes to the pathogenesis of clinical isolate SSU of Aeromonas hydrophila. J Bacteriol (2009) 1.04
Cloning and characterization of an alpha-enolase of the oral pathogen Streptococcus mutans that binds human plasminogen. Biochem Biophys Res Commun (2007) 1.03
The enolase of Borrelia burgdorferi is a plasminogen receptor released in outer membrane vesicles. Infect Immun (2011) 1.03
Two DHH subfamily 1 proteins contribute to pneumococcal virulence and confer protection against pneumococcal disease. Infect Immun (2011) 1.02
Binding of human plasminogen to Bifidobacterium. J Bacteriol (2007) 1.02
Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination. J Biomed Biotechnol (2012) 1.01
Surface-expressed enolases of Plasmodium and other pathogens. Mem Inst Oswaldo Cruz (2011) 1.01
Bacterial plasminogen receptors: mediators of a multifaceted relationship. J Biomed Biotechnol (2012) 0.99
Borrelia burgdorferi enolase is a surface-exposed plasminogen binding protein. PLoS One (2011) 0.96
Enolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites-perspectives for its use as a therapeutic target. Enzyme Res (2011) 0.95
PppA, a surface-exposed protein of Streptococcus pneumoniae, elicits cross-reactive antibodies that reduce colonization in a murine intranasal immunization and challenge model. Infect Immun (2005) 0.95
Cooperative plasminogen recruitment to the surface of Streptococcus canis via M protein and enolase enhances bacterial survival. MBio (2013) 0.95
A surface enolase participates in Borrelia burgdorferi-plasminogen interaction and contributes to pathogen survival within feeding ticks. Infect Immun (2011) 0.93
Contribution of plasminogen activation towards the pathogenic potential of oral streptococci. PLoS One (2010) 0.92
Dancing to another tune-adhesive moonlighting proteins in bacteria. Biology (Basel) (2014) 0.92
α-Enolase, an adhesion-related factor of Mycoplasma bovis. PLoS One (2012) 0.92
Pneumococcal microbial surface components recognizing adhesive matrix molecules targeting of the extracellular matrix. Mol Microbiol (2010) 0.90
Impact of glutamine transporters on pneumococcal fitness under infection-related conditions. Infect Immun (2010) 0.89
The cell surface proteome of Entamoeba histolytica. Mol Cell Proteomics (2013) 0.89
An octamer of enolase from Streptococcus suis. Protein Cell (2012) 0.88
Function of the fibronectin-binding serum opacity factor of Streptococcus pyogenes in adherence to epithelial cells. Infect Immun (2004) 0.88
Human and pneumococcal cell surface glyceraldehyde-3-phosphate dehydrogenase (GAPDH) proteins are both ligands of human C1q protein. J Biol Chem (2012) 0.88
Bacillus anthracis interacts with plasmin(ogen) to evade C3b-dependent innate immunity. PLoS One (2011) 0.88
Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate. J Biol Chem (2009) 0.86
Skizzle is a novel plasminogen- and plasmin-binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation. J Biol Chem (2010) 0.85
Physical Features of Intracellular Proteins that Moonlight on the Cell Surface. PLoS One (2015) 0.84
Interaction of streptococcal plasminogen binding proteins with the host fibrinolytic system. Front Cell Infect Microbiol (2013) 0.82
The interaction of canine plasminogen with Streptococcus pyogenes enolase: they bind to one another but what is the nature of the structures involved? PLoS One (2011) 0.82
Surface-affinity profiling to identify host-pathogen interactions. Infect Immun (2011) 0.81
Repeating structures of the major staphylococcal autolysin are essential for the interaction with human thrombospondin 1 and vitronectin. J Biol Chem (2013) 0.80
Cloning and Characterization of Surface-Localized α-Enolase of Streptococcus iniae, an Effective Protective Antigen in Mice. Int J Mol Sci (2015) 0.80
Potential of known and short prokaryotic protein motifs as a basis for novel peptide-based antibacterial therapeutics: a computational survey. Front Microbiol (2014) 0.79
Crystallization and preliminary X-ray diffraction analysis of phosphoglycerate kinase from Streptococcus pneumoniae. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79
Schistosomes Enhance Plasminogen Activation: The Role of Tegumental Enolase. PLoS Pathog (2015) 0.79
Highly Variable Streptococcus oralis Strains Are Common among Viridans Streptococci Isolated from Primates. mSphere (2016) 0.79
Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase. PLoS One (2015) 0.78
Cold induced Botrytis cinerea enolase (BcEnol-1) functions as a transcriptional regulator and is controlled by cAMP. Mol Genet Genomics (2008) 0.78
Protein moonlighting: what is it, and why is it important? Philos Trans R Soc Lond B Biol Sci (2018) 0.77
The interaction of streptococcal enolase with canine plasminogen: the role of surfaces in complex formation. PLoS One (2014) 0.77
Identification of the actin and plasminogen binding regions of group B streptococcal phosphoglycerate kinase. J Biol Chem (2012) 0.77
Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions. Sci Rep (2016) 0.76
Pathogen activators of plasminogen. J Thromb Haemost (2015) 0.76
Screening and identification of DnaJ interaction proteins in Streptococcus pneumoniae. Curr Microbiol (2013) 0.75
Complete Molecular and Immunoprotective Characterization of Babesia microti Enolase. Front Microbiol (2017) 0.75
Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence. Front Microbiol (2016) 0.75
Network of Surface-Displayed Glycolytic Enzymes in Mycoplasma pneumoniae and Their Interactions with Human Plasminogen. Infect Immun (2015) 0.75
Penicillin binding protein 3 of Staphylococcus aureus NCTC 8325-4 binds and activates human plasminogen. BMC Res Notes (2016) 0.75
Deciphering key residues involved in the virulence-promoting interactions between Streptococcus pneumoniae and human plasminogen. J Biol Chem (2016) 0.75
Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity. Front Microbiol (2017) 0.75
Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells. Sci Rep (2016) 0.75
DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection. Nat Med (2007) 4.35
Public knowledge of benefits of breast and prostate cancer screening in Europe. J Natl Cancer Inst (2009) 3.45
Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem (2004) 2.29
Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae. J Biol Chem (2004) 2.18
Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell (2008) 2.12
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation. Cell Host Microbe (2009) 2.01
Housekeeping enzymes as virulence factors for pathogens. Int J Med Microbiol (2003) 1.96
Virulence profiling of Streptococcus dysgalactiae subspecies equisimilis isolated from infected humans reveals 2 distinct genetic lineages that do not segregate with their phenotypes or propensity to cause diseases. Clin Infect Dis (2007) 1.90
Versatility of pneumococcal surface proteins. Microbiology (2006) 1.80
Platelet factor 4 binds to bacteria, [corrected] inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia. Blood (2010) 1.76
Glyceraldehyde-3-phosphate dehydrogenase of Streptococcus pneumoniae is a surface-displayed plasminogen-binding protein. Infect Immun (2004) 1.74
Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. EMBO J (2004) 1.73
Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. J Biol Chem (2005) 1.68
Reduced ability of penicillin to eradicate ingested group A streptococci from epithelial cells: clinical and pathogenetic implications. Clin Infect Dis (2006) 1.66
The Rho-associated protein kinase p160ROCK is required for centrosome positioning. J Cell Biol (2002) 1.65
The cell wall subproteome of Listeria monocytogenes. Proteomics (2004) 1.55
PavA of Streptococcus pneumoniae modulates adherence, invasion, and meningeal inflammation. Infect Immun (2005) 1.54
A fibrinogen receptor from group B Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sites. Mol Microbiol (2002) 1.52
Pneumococcal association to platelets is mediated by soluble fibrin and supported by thrombospondin-1. Thromb Haemost (2009) 1.51
Peptide-mediated interference with influenza A virus polymerase. J Virol (2007) 1.48
Fibrinolysis and host response in bacterial infections. Thromb Haemost (2007) 1.46
Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo. Immunity (2011) 1.46
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J (2006) 1.45
The M1 protein of Streptococcus pyogenes triggers an innate uptake mechanism into polarized human endothelial cells. J Innate Immun (2014) 1.42
Dual roles of PspC, a surface protein of Streptococcus pneumoniae, in binding human secretory IgA and factor H. J Immunol (2004) 1.41
Plasmin(ogen)-binding alpha-enolase from Streptococcus pneumoniae: crystal structure and evaluation of plasmin(ogen)-binding sites. J Mol Biol (2004) 1.35
Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells. J Cell Sci (2009) 1.35
Identification and characterization of a novel autolysin (Aae) with adhesive properties from Staphylococcus epidermidis. Microbiology (2003) 1.34
PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation. J Biol Chem (2004) 1.25
The nine residue plasminogen-binding motif of the pneumococcal enolase is the major cofactor of plasmin-mediated degradation of extracellular matrix, dissolution of fibrin and transmigration. Thromb Haemost (2005) 1.25
Survival of Streptococcus pyogenes within host phagocytic cells: a pathogenic mechanism for persistence and systemic invasion. J Infect Dis (2003) 1.24
Ectodomains 3 and 4 of human polymeric Immunoglobulin receptor (hpIgR) mediate invasion of Streptococcus pneumoniae into the epithelium. J Biol Chem (2003) 1.23
The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release. J Immunol (2011) 1.21
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. J Biol Chem (2004) 1.21
Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia. Infect Immun (2009) 1.18
Rheumatic fever-associated Streptococcus pyogenes isolates aggregate collagen. J Clin Invest (2003) 1.15
Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes reveals an unusual activation program. Infect Immun (2007) 1.15
PavB is a surface-exposed adhesin of Streptococcus pneumoniae contributing to nasopharyngeal colonization and airways infections. Mol Microbiol (2010) 1.14
Thrombospondin-1 promotes cellular adherence of gram-positive pathogens via recognition of peptidoglycan. FASEB J (2007) 1.13
Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. PLoS One (2009) 1.13
Complement regulator Factor H mediates a two-step uptake of Streptococcus pneumoniae by human cells. J Biol Chem (2010) 1.13
Host cell caveolae act as an entry-port for group A streptococci. Cell Microbiol (2003) 1.13
Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association. Angew Chem Int Ed Engl (2010) 1.13
The complement fitness factor H: role in human diseases and for immune escape of pathogens, like pneumococci. Vaccine (2008) 1.12
Defining the structural basis of human plasminogen binding by streptococcal surface enolase. J Biol Chem (2009) 1.12
Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity. Antiviral Res (2010) 1.12
The streptococcal lipoprotein rotamase A (SlrA) is a functional peptidyl-prolyl isomerase involved in pneumococcal colonization. J Biol Chem (2005) 1.11
A community standard format for the representation of protein affinity reagents. Mol Cell Proteomics (2009) 1.11
Inference of genetic regulatory networks with recurrent neural network models using particle swarm optimization. IEEE/ACM Trans Comput Biol Bioinform (2007) 1.11
Cytosolic proteins contribute to surface plasminogen recruitment of Neisseria meningitidis. J Bacteriol (2007) 1.10
Minimum information about a protein affinity reagent (MIAPAR). Nat Biotechnol (2010) 1.10
More than one tandem repeat domain of the extracellular adherence protein of Staphylococcus aureus is required for aggregation, adherence, and host cell invasion but not for leukocyte activation. Infect Immun (2008) 1.09
Plasminogen binding by group A streptococcal isolates from a region of hyperendemicity for streptococcal skin infection and a high incidence of invasive infection. Infect Immun (2004) 1.09
Microevolution of group A streptococci in vivo: capturing regulatory networks engaged in sociomicrobiology, niche adaptation, and hypervirulence. PLoS One (2010) 1.09
Biochemical and NMR analyses of an SF3b155-p14-U2AF-RNA interaction network involved in branch point definition during pre-mRNA splicing. RNA (2006) 1.09
Molecular and functional characterization of clathrin- and AP-2-binding determinants within a disordered domain of auxilin. J Biol Chem (2003) 1.08
Intracellular survival of Streptococcus pyogenes in polymorphonuclear cells results in increased bacterial virulence. Infect Immun (2003) 1.08
High-avidity human serum antibodies recognizing linear epitopes of Borna disease virus proteins. Biol Psychiatry (2002) 1.08
Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol (2005) 1.08
The granulocyte receptor carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) directly associates with Vav to promote phagocytosis of human pathogens. J Immunol (2007) 1.06
Identification of a streptococcal octapeptide motif involved in acute rheumatic fever. J Biol Chem (2007) 1.04
Immunization of pigs to prevent disease in humans: construction and protective efficacy of a Salmonella enterica serovar Typhimurium live negative-marker vaccine. Infect Immun (2007) 1.04
High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides. Biochem J (2006) 1.04
Contribution of natural killer cells to the pathogenesis of septic shock induced by Streptococcus pyogenes in mice. J Infect Dis (2005) 1.04
Bifidobacterial enolase, a cell surface receptor for human plasminogen involved in the interaction with the host. Microbiology (2009) 1.04
Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infect Immun (2008) 1.04
Molecular cloning of an alpha-enolase from the human filarial parasite Onchocerca volvulus that binds human plasminogen. Biochim Biophys Acta (2003) 1.04
Fibronectin-binding protein gene recombination and horizontal transfer between group A and G streptococci. J Clin Microbiol (2004) 1.03
DnaK from Bifidobacterium animalis subsp. lactis is a surface-exposed human plasminogen receptor upregulated in response to bile salts. Microbiology (2010) 1.03
P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae: defined domains of P159 bind heparin and promote adherence to eukaryote cells. Mol Microbiol (2006) 1.03
Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci, southern India. Emerg Infect Dis (2010) 1.03
Enolase of Streptococcus pneumoniae binds human complement inhibitor C4b-binding protein and contributes to complement evasion. J Immunol (2012) 1.02
Invasion mechanisms of Gram-positive pathogenic cocci. Thromb Haemost (2007) 1.02
Binding of human plasminogen to Bifidobacterium. J Bacteriol (2007) 1.02
The interaction of the gammaherpesvirus 68 orf73 protein with cellular BET proteins affects the activation of cell cycle promoters. J Virol (2009) 1.01
The choline-binding protein PspC of Streptococcus pneumoniae interacts with the C-terminal heparin-binding domain of vitronectin. J Biol Chem (2013) 1.01
Genomic organization, structure, regulation and pathogenic role of pilus constituents in major pathogenic Streptococci and Enterococci. Int J Med Microbiol (2010) 1.00
Influence of proteins Bsp and FemH on cell shape and peptidoglycan composition in group B streptococcus. Microbiology (2002) 1.00
Streptococcus pyogenes recruits collagen via surface-bound fibronectin: a novel colonization and immune evasion mechanism. Mol Microbiol (2003) 1.00
Streptococcus pneumoniae enolase is important for plasminogen binding despite low abundance of enolase protein on the bacterial cell surface. Microbiology (2006) 1.00
Identification of high-affinity PB1-derived peptides with enhanced affinity to the PA protein of influenza A virus polymerase. Antimicrob Agents Chemother (2010) 0.99
14-3-3 proteins are constituents of the insoluble glycoprotein framework of the chlamydomonas cell wall. Plant Cell (2003) 0.99
Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes. Blood (2012) 0.99
Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling. J Biol Chem (2004) 0.99
Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus. PLoS One (2009) 0.98
An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA. Front Cell Infect Microbiol (2012) 0.98
The interaction between bacterial enolase and plasminogen promotes adherence of Streptococcus pneumoniae to epithelial and endothelial cells. Int J Med Microbiol (2013) 0.97
Cdc42 and the phosphatidylinositol 3-kinase-Akt pathway are essential for PspC-mediated internalization of pneumococci by respiratory epithelial cells. J Biol Chem (2009) 0.97
Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha. Mol Biol Cell (2006) 0.97
N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus. J Hepatol (2010) 0.97
Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. J Innate Immun (2010) 0.97
Combat pneumococcal infections: adhesins as candidates for protein-based vaccine development. Curr Drug Targets (2012) 0.97
Hydrogen peroxide-mediated killing of Caenorhabditis elegans: a common feature of different streptococcal species. Infect Immun (2004) 0.97
Characterization of central carbon metabolism of Streptococcus pneumoniae by isotopologue profiling. J Biol Chem (2011) 0.96