Published in Mol Ther on July 01, 2003
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. Mol Ther (2006) 4.64
Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice. J Virol (2005) 3.28
In vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animals. Sensors (Basel) (2010) 1.33
Stable human FIX expression after 0.9G intrauterine gene transfer of self-complementary adeno-associated viral vector 5 and 8 in macaques. Mol Ther (2011) 1.00
Frequency and spectrum of genomic integration of recombinant adeno-associated virus serotype 8 vector in neonatal mouse liver. J Virol (2008) 0.94
Structural insights into adeno-associated virus serotype 5. J Virol (2013) 0.92
Role of antigen-specific regulatory CD4+CD25+ T cells in tolerance induction after neonatal IP administration of AAV-hF.IX. Gene Ther (2013) 0.91
Impact of age at administration, lysosomal storage, and transgene regulatory elements on AAV2/8-mediated rat liver transduction. PLoS One (2012) 0.83
Kidney-specific expression of GFP by in-utero delivery of pseudotyped adeno-associated virus 9. Mol Ther Methods Clin Dev (2014) 0.81
Factors determining the risk of inadvertent retroviral transduction of male germ cells after in utero gene transfer in sheep. Hum Gene Ther (2009) 0.81
Benefits of Neuronal Preferential Systemic Gene Therapy for Neurotransmitter Deficiency. Mol Ther (2015) 0.76
Gene therapy to the kidney using viral vectors. Paidiatrike (2008) 0.75
Transfer of Therapeutic Genes into Fetal Rhesus Monkeys using Recombinant Adeno-Associated Type I Viral Vectors. Hum Gene Ther Clin Dev (2016) 0.75
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature (2004) 5.61
Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. Nat Med (2008) 4.83
Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A (2003) 4.41
Adipose-derived adult stromal cells heal critical-size mouse calvarial defects. Nat Biotechnol (2004) 4.16
Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production. Blood (2006) 3.33
Dual-axis confocal microscope for high-resolution in vivo imaging. Opt Lett (2003) 3.16
In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood (2005) 3.13
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Proc Natl Acad Sci U S A (2010) 2.89
Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging. Blood (2002) 2.79
Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. J Biomed Opt (2005) 2.69
Extracellular replication of Listeria monocytogenes in the murine gall bladder. Science (2004) 2.58
Chemical control of protein stability and function in living mice. Nat Med (2008) 2.37
Synergistic antitumor effects of immune cell-viral biotherapy. Science (2006) 2.37
Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation (2008) 2.22
Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem Photobiol (2002) 2.18
Dual-axes confocal reflectance microscope for distinguishing colonic neoplasia. J Biomed Opt (2006) 2.17
In vivo imaging using bioluminescence: a tool for probing graft-versus-host disease. Nat Rev Immunol (2006) 2.06
Miniature near-infrared dual-axes confocal microscope utilizing a two-dimensional microelectromechanical systems scanner. Opt Lett (2007) 2.06
Efficient rejection of scattered light enables deep optical sectioning in turbid media with low-numerical-aperture optics in a dual-axis confocal architecture. J Biomed Opt (2008) 1.99
Optical monitoring and treatment of potentially lethal wound infections in vivo. J Infect Dis (2003) 1.98
Guided by the light: visualizing biomolecular processes in living animals with bioluminescence. Curr Opin Chem Biol (2009) 1.97
Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93
Design and evaluation of a variable aperture collimator for conformal radiotherapy of small animals using a microCT scanner. Med Phys (2007) 1.90
In vivo bioluminescence imaging for integrated studies of infection. Cell Microbiol (2004) 1.89
Functional imaging of colonic mucosa with a fibered confocal microscope for real-time in vivo pathology. Clin Gastroenterol Hepatol (2007) 1.85
Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation (2005) 1.82
Correlation of sonographic findings and outcome in necrotizing enterocolitis. Pediatr Radiol (2007) 1.81
In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury. FASEB J (2005) 1.80
Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. Transplantation (2009) 1.73
Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters. Proc Natl Acad Sci U S A (2008) 1.71
Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. Blood (2008) 1.70
Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1. J Mol Med (Berl) (2002) 1.70
Development of therapeutic siRNAs for pachyonychia congenita. J Invest Dermatol (2007) 1.67
Luciferin derivatives for enhanced in vitro and in vivo bioluminescence assays. Biochemistry (2006) 1.67
Generic and personalized RNAi-based therapeutics for a dominant-negative epidermal fragility disorder. J Invest Dermatol (2012) 1.66
In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract. J Biomed Opt (2012) 1.49
Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs. Blood (2007) 1.48
Single-nucleotide-specific siRNA targeting in a dominant-negative skin model. J Invest Dermatol (2007) 1.46
Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice. Am J Pathol (2009) 1.44
KLF2 is essential for primitive erythropoiesis and regulates the human and murine embryonic beta-like globin genes in vivo. Blood (2005) 1.44
Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. J Immunol (2005) 1.39
p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. J Immunol (2004) 1.36
Three-dimensional in vivo imaging by a handheld dual-axes confocal microscope. Opt Express (2008) 1.35
Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation. Bioconjug Chem (2006) 1.35
Quantifying cell-surface biomarker expression in thick tissues with ratiometric three-dimensional microscopy. Biophys J (2009) 1.33
Hemin-activated macrophages home to the pancreas and protect from acute pancreatitis via heme oxygenase-1 induction. J Clin Invest (2005) 1.31
Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease. Blood (2006) 1.31
Animal models of bone metastasis. Cancer (2003) 1.29
Dual-axes confocal microscopy with post-objective scanning and low-coherence heterodyne detection. Opt Lett (2003) 1.29
Micromirror-scanned dual-axis confocal microscope utilizing a gradient-index relay lens for image guidance during brain surgery. J Biomed Opt (2010) 1.27
Enhancing poxvirus oncolytic effects through increased spread and immune evasion. Cancer Res (2008) 1.26
Monitoring age-related susceptibility of young mice to oral Salmonella enterica serovar Typhimurium infection using an in vivo murine model. Pediatr Res (2005) 1.26
Evaluation of effector cell fate and function by in vivo bioluminescence imaging. Methods (2003) 1.25
Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release. J Am Chem Soc (2006) 1.23
Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover. Tissue Eng (2005) 1.23
Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood (2002) 1.21
Breast-milk shedding of drug-resistant HIV-1 subtype C in women exposed to single-dose nevirapine. J Infect Dis (2005) 1.20
Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study. Clin Cancer Res (2006) 1.20
Ethanol locks to prevent catheter-related bloodstream infections in parenteral nutrition: a meta-analysis. Pediatrics (2012) 1.19
A Raman-based endoscopic strategy for multiplexed molecular imaging. Proc Natl Acad Sci U S A (2013) 1.18
Confocal fluorescence microscope with dual-axis architecture and biaxial postobjective scanning. J Biomed Opt (2004) 1.16
Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals. Mol Imaging (2004) 1.16
Detection of endogenous biomolecules in Barrett's esophagus by Fourier transform infrared spectroscopy. Proc Natl Acad Sci U S A (2007) 1.16
Targeting localized immune suppression within the tumor through repeat cycles of immune cell-oncolytic virus combination therapy. Mol Ther (2010) 1.15
In vivo micro-image mosaicing. IEEE Trans Biomed Eng (2010) 1.14
Elements of successful intestinal rehabilitation. J Pediatr Surg (2011) 1.14
Induced biliary excretion of Listeria monocytogenes. Infect Immun (2006) 1.13
Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice. Proc Natl Acad Sci U S A (2007) 1.12
The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. J Immunol (2009) 1.11
Point-of-care pathology with miniature microscopes. Anal Cell Pathol (Amst) (2011) 1.11
Lymphoid-tissue-specific homing of bone-marrow-derived dendritic cells. Blood (2009) 1.10
Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction. Circ Cardiovasc Imaging (2009) 1.08
Stability study of unmodified siRNA and relevance to clinical use. Oligonucleotides (2008) 1.08
Understanding immune cell trafficking patterns via in vivo bioluminescence imaging. J Cell Biochem Suppl (2002) 1.07
Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD). Mol Ther (2010) 1.04
Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3. Cancer Res (2002) 1.02
Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding. J Biol Chem (2011) 1.01
Donor CD8+ T cells mediate graft-versus-leukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody. J Immunol (2007) 1.01
New enzyme for reductive cancer chemotherapy, YieF, and its improvement by directed evolution. Mol Cancer Ther (2006) 1.00
Fibered confocal microscopy of bladder tumors: an ex vivo study. J Endourol (2009) 1.00
Use of self-delivery siRNAs to inhibit gene expression in an organotypic pachyonychia congenita model. J Invest Dermatol (2011) 1.00
Intraurethral knot in a very-low-birth-weight infant: radiological recognition, surgical management and prevention. Pediatr Radiol (2005) 1.00
Assessment of cellular response to thermal laser injury through bioluminescence imaging of heat shock protein 70. Photochem Photobiol (2004) 0.99
In vivo sustained release of siRNA from solid lipid nanoparticles. ACS Nano (2011) 0.99
TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly phosphorylated, and indicates poor prognosis in node-negative breast cancer. Cancer Res (2009) 0.99
IL-12 enhances efficacy and shortens enrichment time in cytokine-induced killer cell immunotherapy. Cancer Immunol Immunother (2010) 0.98
The importance of being red. Nat Biotechnol (2009) 0.98
Regulation of intestine-specific spatiotemporal expression by the rat lactase promoter. J Biol Chem (2002) 0.98
CNOB/ChrR6, a new prodrug enzyme cancer chemotherapy. Mol Cancer Ther (2009) 0.97
Selective intratumoral amplification of an antiangiogenic vector by an oncolytic virus produces enhanced antivascular and anti-tumor efficacy. Mol Ther (2006) 0.97
Heme oxygenase-1 deletion affects stress erythropoiesis. PLoS One (2011) 0.97
Foci of Listeria monocytogenes persist in the bone marrow. Dis Model Mech (2008) 0.96
Low levels of Her2/neu expressed by Ewing's family tumor cell lines can redirect cytokine-induced killer cells. Clin Cancer Res (2005) 0.96
High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device. J Biomed Opt (2013) 0.96
Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model. Mol Ther (2005) 0.96
Gene transfer via reversible plasmid condensation with cysteine-flanked, internally spaced arginine-rich peptides. Hum Gene Ther (2003) 0.95
Small evidence for small incisions: pediatric laparoscopy and the need for more rigorous evaluation of novel surgical therapies. J Pediatr Surg (2003) 0.93
Expression and regulation of heme oxygenase isozymes in the developing mouse cortex. Pediatr Res (2006) 0.93
Efficacy of antimicrobial peptoids against Mycobacterium tuberculosis. Antimicrob Agents Chemother (2011) 0.93