Published in Nat Immunol on August 01, 2003
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol (2005) 7.44
Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol (2009) 5.59
Cancer immunotherapy via dendritic cells. Nat Rev Cancer (2012) 5.37
Imaging the single cell dynamics of CD4+ T cell activation by dendritic cells in lymph nodes. J Exp Med (2004) 5.08
Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest (2007) 5.05
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol (2005) 4.01
T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A (2004) 3.99
Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity (2008) 3.48
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell (2013) 3.22
Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response. J Exp Med (2005) 3.14
CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells. J Exp Med (2007) 2.39
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med (2009) 2.12
Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes. Nat Immunol (2010) 1.97
Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity. Nat Rev Cancer (2012) 1.78
Airway eosinophils: allergic inflammation recruited professional antigen-presenting cells. J Immunol (2007) 1.78
Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. J Exp Med (2006) 1.77
Organ-dependent in vivo priming of naive CD4+, but not CD8+, T cells by plasmacytoid dendritic cells. J Exp Med (2007) 1.68
Innate control of adaptive immunity via remodeling of lymph node feed arteriole. Proc Natl Acad Sci U S A (2005) 1.62
Retracted Novel APC-like properties of human NK cells directly regulate T cell activation. J Clin Invest (2004) 1.58
Trial watch: Dendritic cell-based interventions for cancer therapy. Oncoimmunology (2012) 1.51
Adaptive immunity in atherogenesis: new insights and therapeutic approaches. J Clin Invest (2013) 1.43
The activation and inactivation of mature CD4 T cells: a case for peripheral self-nonself discrimination. Scand J Immunol (2014) 1.41
Adaptive immunity to fungi. Annu Rev Immunol (2012) 1.41
The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells. Nat Immunol (2013) 1.36
Interactions of tumor cells with dendritic cells: balancing immunity and tolerance. Cell Death Differ (2007) 1.35
IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system. Science (2015) 1.32
Complete differentiation of CD8+ T cells activated locally within the transplanted liver. J Exp Med (2006) 1.25
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A (2009) 1.24
mTOR at the crossroads of T cell proliferation and tolerance. Semin Immunol (2007) 1.22
Virulent Salmonella enterica serovar typhimurium evades adaptive immunity by preventing dendritic cells from activating T cells. Infect Immun (2006) 1.21
TLR7 enables cross-presentation by multiple dendritic cell subsets through a type I IFN-dependent pathway. Blood (2011) 1.21
Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells. Proc Natl Acad Sci U S A (2008) 1.16
Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage. J Immunol (2012) 1.15
In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity. Blood (2005) 1.13
The role of B cells and humoral immunity in Mycobacterium tuberculosis infection. Adv Exp Med Biol (2013) 1.09
TACI-BLyS signaling via B-cell-dendritic cell cooperation is required for naive CD8+ T-cell priming in vivo. Blood (2005) 1.09
The microanatomy of B cell activation. Curr Opin Immunol (2009) 1.04
Immunization of NSCLC patients with antigen-pulsed immature autologous dendritic cells. Lung Cancer (2007) 1.03
Chronic ethanol consumption decreases murine Langerhans cell numbers and delays migration of Langerhans cells as well as dermal dendritic cells. Alcohol Clin Exp Res (2008) 1.01
Alphavirus replicon particles acting as adjuvants promote CD8+ T cell responses to co-delivered antigen. Vaccine (2008) 0.99
Tumor antigen cross-presentation and the dendritic cell: where it all begins? Clin Dev Immunol (2010) 0.97
MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo. PLoS One (2009) 0.97
Location, location, location: tissue-specific regulation of immune responses. J Leukoc Biol (2013) 0.96
Functional roles of immature dendritic cells in impaired immunity of solid tumour and their targeted strategies for provoking tumour immunity. Clin Exp Immunol (2006) 0.96
Intraclonal competition inhibits the formation of high-affinity antibody-secreting cells. J Immunol (2008) 0.95
Prolonged survival of allografts induced by mycobacterial Hsp70 is dependent on CD4+CD25+ regulatory T cells. PLoS One (2010) 0.95
The lymph as a pool of self-antigens. Trends Immunol (2010) 0.95
Immune complex-induced enhancement of bacterial antigen presentation requires Fcgamma receptor III expression on dendritic cells. Proc Natl Acad Sci U S A (2007) 0.94
Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers. Infect Immun (2007) 0.92
Haemophilus ducreyi partially activates human myeloid dendritic cells. Infect Immun (2007) 0.92
Th2 polarization in peripheral blood mononuclear cells from human immunodeficiency virus (HIV)-infected subjects, as activated by HIV virus-like particles. J Virol (2008) 0.90
A new view on cutaneous dendritic cell subsets in experimental leishmaniasis. Med Microbiol Immunol (2006) 0.90
Innate immunostimulatory properties of allergens and their relevance to food allergy. Semin Immunopathol (2012) 0.89
A micro-sterile inflammation array as an adjuvant for influenza vaccines. Nat Commun (2014) 0.88
Nanovectorized radiotherapy: a new strategy to induce anti-tumor immunity. Front Oncol (2012) 0.87
Potent inhibitors of pro-inflammatory cytokine production produced by a marine-derived bacterium. J Med Chem (2009) 0.87
CD4+ T Cells: guardians of the phagosome. Clin Microbiol Rev (2014) 0.87
Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses. J Immunol (2012) 0.86
Functional reprogramming of the primary immune response by T cell receptor antagonism. J Exp Med (2004) 0.86
The α4 nicotinic receptor promotes CD4+ T-cell proliferation and a helper T-cell immune response. Mol Pharmacol (2013) 0.85
Bridging channel dendritic cells induce immunity to transfused red blood cells. J Exp Med (2016) 0.85
Sentinel node lymphocytes: tumour reactive lymphocytes identified intraoperatively for the use in immunotherapy of colon cancer. Br J Cancer (2006) 0.85
What determines the success or failure of intracellular cutaneous parasites? Lessons learned from leishmaniasis. Med Microbiol Immunol (2009) 0.85
Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag. Vaccine (2006) 0.85
The role of mucosal T lymphocytes in regulating intestinal inflammation. Springer Semin Immunopathol (2005) 0.85
Cholera toxin impairs the differentiation of monocytes into dendritic cells, inducing professional antigen-presenting myeloid cells. Infect Immun (2010) 0.84
Potential functional role of plasmacytoid dendritic cells in cancer immunity. Immunology (2007) 0.84
Antigen display, T-cell activation, and immune evasion during acute and chronic ehrlichiosis. Infect Immun (2009) 0.84
Immune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy. Open AIDS J (2014) 0.83
MHC class II expression in pancreatic tumors: a link to intratumoral inflammation. Virchows Arch (2011) 0.83
Tolerance and lymphoid organ structure and function. Front Immunol (2011) 0.83
Investigating the immunologic effects of CoCr nanoparticles. Clin Orthop Relat Res (2009) 0.83
Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues. Proc Am Thorac Soc (2007) 0.82
Adoptively transferred dendritic cells restore primary cell-mediated inflammatory competence to acutely malnourished weanling mice. Am J Pathol (2008) 0.82
Engaging adaptive immunity with biomaterials. J Mater Chem B Mater Biol Med (2014) 0.81
Gene carriers and transfection systems used in the recombination of dendritic cells for effective cancer immunotherapy. Clin Dev Immunol (2010) 0.81
Transiently antigen-primed B cells return to naive-like state in absence of T-cell help. Nat Commun (2017) 0.80
Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo. Immunology (2007) 0.80
The second touch hypothesis: T cell activation, homing and polarization. F1000Res (2014) 0.80
T cell-macrophage interactions and granuloma formation in vasculitis. Front Immunol (2014) 0.80
B-1a B cells regulate T cell differentiation associated with pregnancy disturbances. Front Immunol (2014) 0.79
Extravascular CX3CR1+ cells extend intravascular dendritic processes into intact central nervous system vessel lumen. Microsc Microanal (2013) 0.79
Adventitial inflammation and its interaction with intimal atherosclerotic lesions. Front Physiol (2014) 0.79
Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis. Front Physiol (2012) 0.79
Roles of Mucosal Immunity against Mycobacterium tuberculosis Infection. Tuberc Res Treat (2012) 0.79
Distinct modes of antigen presentation promote the formation, differentiation, and activity of foxp3+ regulatory T cells in vivo. J Immunol (2015) 0.79
Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs. Front Immunol (2016) 0.78
Glyphosate-rich air samples induce IL-33, TSLP and generate IL-13 dependent airway inflammation. Toxicology (2014) 0.78
Co-expression of miRNA targeting the expression of PERK, but not PKR, enhances cellular immunity from an HIV-1 Env DNA vaccine. PLoS One (2011) 0.78
Interleukin 10 (IL-10)-mediated Immunosuppression: MARCH-I INDUCTION REGULATES ANTIGEN PRESENTATION BY MACROPHAGES BUT NOT DENDRITIC CELLS. J Biol Chem (2015) 0.78
Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice. Nat Nanotechnol (2016) 0.77
Contribution of Fcγ receptors to human respiratory syncytial virus pathogenesis and the impairment of T-cell activation by dendritic cells. Immunology (2015) 0.77
Dendritic cells sequester antigenic epitopes for prolonged periods in the absence of antigen-encoding genetic information. Proc Natl Acad Sci U S A (2012) 0.77
Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy. Annu Rev Biomed Eng (2016) 0.77
Downregulation of key early events in the mobilization of antigen-bearing dendritic cells by leukocyte immunoglobulin-like Receptor B4 in a mouse model of allergic pulmonary inflammation. PLoS One (2013) 0.76
Perturbations of mucosal homeostasis through interactions of intestinal microbes with myeloid cells. Immunobiology (2014) 0.76
Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity. J Med Chem (2015) 0.76
Role of secondary lymphoid tissues in primary and memory T-cell responses to a transplanted organ. Transplant Rev (Orlando) (2009) 0.75
Intralymphatic immunotherapy and vaccination in mice. J Vis Exp (2014) 0.75
Draft Genome Sequence of Marine Bacterium Streptomyces sp. Strain CNQ431, a Producer of the Cytokine Inhibitor Splenocin. Genome Announc (2015) 0.75
Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity (2007) 9.26
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity (2003) 5.52
Naive and memory CD4+ T cell survival controlled by clonal abundance. Science (2006) 4.67
Different B cell populations mediate early and late memory during an endogenous immune response. Science (2011) 3.63
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. Immunity (2011) 3.58
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity (2008) 3.56
Tracking salmonella-specific CD4 T cells in vivo reveals a local mucosal response to a disseminated infection. Immunity (2002) 3.42
The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles. Immunity (2007) 3.28
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell (2013) 3.22
Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells. Nat Immunol (2009) 3.19
Tracking epitope-specific T cells. Nat Protoc (2009) 2.96
Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection. Am J Transplant (2003) 2.69
Origins of CD4(+) effector and central memory T cells. Nat Immunol (2011) 2.35
CD4+ T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells. J Exp Med (2006) 1.97
Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation. J Exp Med (2003) 1.87
A germinal center-independent pathway generates unswitched memory B cells early in the primary response. J Exp Med (2012) 1.86
Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A (2010) 1.85
Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. Immunity (2009) 1.84
Visualizing the first 50 hr of the primary immune response to a soluble antigen. Immunity (2004) 1.66
Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells. Proc Natl Acad Sci U S A (2011) 1.54
Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proc Natl Acad Sci U S A (2012) 1.41
Pillars article: visualization of Peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity. 1994. 1: 327-339. J Immunol (2013) 1.40
Visualization of the genesis and fate of isotype-switched B cells during a primary immune response. J Exp Med (2003) 1.38
Arthritogenic self-reactive CD4+ T cells acquire an FR4hiCD73hi anergic state in the presence of Foxp3+ regulatory T cells. J Immunol (2011) 1.32
T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity (2015) 1.29
Heterogeneity in the differentiation and function of memory B cells. Trends Immunol (2012) 1.25
In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen. J Immunol (2002) 1.18
IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands. Eur J Immunol (2004) 1.18
In vivo antigen presentation. Curr Opin Immunol (2004) 1.18
Negative selection and peptide chemistry determine the size of naive foreign peptide-MHC class II-specific CD4+ T cell populations. J Immunol (2010) 1.18
Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development. PLoS Pathog (2012) 1.18
Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen. J Exp Med (2012) 1.15
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire. Proc Natl Acad Sci U S A (2009) 1.09
In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance. J Immunol (2005) 1.08
CD4+ memory T cell survival. Curr Opin Immunol (2011) 1.07
Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection. Eur J Immunol (2004) 1.07
Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infection. PLoS Pathog (2011) 1.07
CD4+ T cell persistence and function after infection are maintained by low-level peptide:MHC class II presentation. J Immunol (2013) 1.05
PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes. Diabetes (2013) 1.04
CCR6-dependent recruitment of blood phagocytes is necessary for rapid CD4 T cell responses to local bacterial infection. Proc Natl Acad Sci U S A (2007) 1.01
Cutting edge: type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice. J Immunol (2013) 1.00
Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo. J Immunol (2008) 0.97
Tracking antigen-specific CD4+ T cells throughout the course of chronic Leishmania major infection in resistant mice. Eur J Immunol (2012) 0.89
The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation. Immunity (2012) 0.88
A protease-dependent mechanism for initiating T-dependent B cell responses to large particulate antigens. J Immunol (2010) 0.88
CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia. J Immunol (2006) 0.87
CD4+ T Cells: guardians of the phagosome. Clin Microbiol Rev (2014) 0.87
On the trail of arthritogenic T cells. Arthritis Rheum (2011) 0.83
Whole-body analysis of T cell responses. Curr Opin Immunol (2003) 0.83
CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs. J Immunol (2012) 0.82
Migration and accumulation of effector CD4+ T cells in nonlymphoid tissues. Proc Am Thorac Soc (2007) 0.82
CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia. J Immunol (2010) 0.81
Response to comment on “The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude”. J Immunol (2013) 0.75
Flow cytometric analysis of T cell receptor signal transduction. Sci STKE (2002) 0.75
SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with non-severe disease. bioRxiv (2020) 0.75