Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis.

PubWeight™: 2.12‹?› | Rank: Top 2%

🔗 View Article (PMID 12917302)

Published in N Engl J Med on August 14, 2003


Vera M R Heydendael1, Phyllis I Spuls, Brent C Opmeer, Corianne A J M de Borgie, Johannes B Reitsma, Wouter F M Goldschmidt, Patrick M M Bossuyt, Jan D Bos, Menno A de Rie

Author Affiliations

1: Department of Dermatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Articles citing this

Home versus outpatient ultraviolet B phototherapy for mild to severe psoriasis: pragmatic multicentre randomised controlled non-inferiority trial (PLUTO study). BMJ (2009) 2.25

Safety and Efficacy of Methotrexate in Psoriasis: A Meta-Analysis of Published Trials. PLoS One (2016) 1.38

Quality of life in patients with psoriasis. Health Qual Life Outcomes (2006) 1.31

Dermatologist preferences for first-line therapy of moderate to severe psoriasis in healthy adult patients. J Am Acad Dermatol (2011) 1.18

Psoriasis and its management. BMJ (2006) 1.05

Efalizumab: results of a 3-year continuous dosing study for the long-term control of psoriasis. Br J Dermatol (2008) 1.02

Systemic treatment with either cyclosporin A or methotrexate does not influence the T helper 1/T helper 2 balance in psoriatic patients. J Clin Immunol (2004) 1.00

A randomized, double-blind, placebo-controlled study to evaluate the addition of methotrexate to etanercept in patients with moderate to severe plaque psoriasis. Br J Dermatol (2012) 0.96

German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version). Arch Dermatol Res (2007) 0.94

A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis. Ann Rheum Dis (2004) 0.89

The effect of cyclosporin A on airway cell proinflammatory signaling and pneumonia. Am J Respir Cell Mol Biol (2005) 0.88

Impact of efalizumab on patient-reported outcomes in high-need psoriasis patients: results of the international, randomized, placebo-controlled Phase III Clinical Experience Acquired with Raptiva (CLEAR) trial [NCT00256139]. BMC Dermatol (2005) 0.88

Impact of methotrexate on oxidative stress and apoptosis markers in psoriatic patients. Clin Exp Med (2013) 0.87

Antifolate activity of epigallocatechin gallate against Stenotrophomonas maltophilia. Antimicrob Agents Chemother (2005) 0.86

Clinical, Quality of Life, Patient Adherence, and Safety Outcomes of Short-Course (12 Weeks) Treatment with Cyclosporine in Patients with Severe Psoriasis (the Practice Study). Ann Dermatol (2013) 0.84

Use of antioxidants to prevent cyclosporine a toxicity. Toxicol Res (2010) 0.82

Nail Psoriasis: A Review of Treatment Options. Drugs (2016) 0.82

Psoriasis: advances in pathophysiology and management. Postgrad Med J (2007) 0.82

Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting. J Am Acad Dermatol (2014) 0.81

Synovitis in psoriatic arthritis: immunohistochemistry, comparisons with rheumatoid arthritis, and effects of therapy. Curr Rheumatol Rep (2011) 0.80

Cyclosporine regimens in plaque psoriasis: an overview with special emphasis on dose, duration, and old and new treatment approaches. ScientificWorldJournal (2013) 0.80

Nitric oxide levels in patients with psoriasis treated with methotrexate. Mediators Inflamm (2006) 0.79

Expression of IL-20 in synovium and lesional skin of patients with psoriatic arthritis: differential response to alefacept treatment. Arthritis Res Ther (2012) 0.79

The effect of folic acid supplementation on the pharmacokinetics and pharmacodynamics of oral methotrexate during the remission-induction period of treatment for moderate-to-severe plaque psoriasis. Eur J Clin Pharmacol (2007) 0.78

Dipeptidyl peptidase-4 inhibition and narrow-band ultraviolet-B light in psoriasis (DINUP): study protocol for a randomised controlled trial. Trials (2016) 0.77

Update of the management of chronic psoriasis: new approaches and emerging treatment options. Clin Cosmet Investig Dermatol (2010) 0.76

Treating psoriasis with adalimumab. Ther Clin Risk Manag (2008) 0.76

A study of the use of drugs in patients suffering from psoriasis and their impact on quality of life. Indian J Pharmacol (2017) 0.75

Refractory atopic dermatitis in childhood: improvement with methotrexate? Ann Dermatol (2013) 0.75

Comparison of methotrexate and cyclosporine therapy in psoriasis. Curr Rheumatol Rep (2004) 0.75

Immunotargeting in the management of psoriasis. Immunotargets Ther (2013) 0.75

Current and potential immune therapies and vaccines in the management of psoriasis. Hum Vaccin Immunother (2014) 0.75

Psoriasis (chronic plaque). BMJ Clin Evid (2009) 0.75

Efficacy of Methotrexate in patients with plaque type psoriasis. Pak J Med Sci (2014) 0.75

The Role of Pharmacogenetics in Chronic Plaque Psoriasis: Update of the Literature. Mol Diagn Ther (2017) 0.75

Randomized Placebo Control Study of Metformin in Psoriasis Patients with Metabolic Syndrome (Systemic Treatment Cohort). Indian J Endocrinol Metab (2017) 0.75

Articles by these authors

The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol (2003) 16.17

QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med (2011) 15.02

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. BMJ (2003) 10.80

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. Ann Intern Med (2003) 10.28

Preoperative biliary drainage for cancer of the head of the pancreas. N Engl J Med (2010) 10.21

Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative. Ann Intern Med (2003) 8.58

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic Accuracy. Clin Chem (2003) 8.13

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. Clin Chem (2003) 7.92

Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial. Lancet (2003) 7.91

Clinical features and prognostic factors in adults with bacterial meningitis. N Engl J Med (2004) 7.87

The diagnostic odds ratio: a single indicator of test performance. J Clin Epidemiol (2003) 7.54

Sources of variation and bias in studies of diagnostic accuracy: a systematic review. Ann Intern Med (2004) 6.87

Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol (2006) 6.03

Systematic reviews of diagnostic test accuracy. Ann Intern Med (2008) 4.84

Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): the TRIPOD statement. Ann Intern Med (2015) 4.32

Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol (2006) 3.78

Exploring sources of heterogeneity in systematic reviews of diagnostic tests. Stat Med (2002) 3.61

Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging--a meta-analysis. Radiology (2004) 3.55

Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report. Lancet Oncol (2011) 3.36

Evidence of bias and variation in diagnostic accuracy studies. CMAJ (2006) 3.34

Cranberries vs antibiotics to prevent urinary tract infections: a randomized double-blind noninferiority trial in premenopausal women. Arch Intern Med (2011) 3.33

Comparison of on-demand vs planned relaparotomy strategy in patients with severe peritonitis: a randomized trial. JAMA (2007) 3.30

Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women. Arch Intern Med (2012) 3.14

Probabilistic record linkage is a valid and transparent tool to combine databases without a patient identification number. J Clin Epidemiol (2007) 3.00

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Fam Pract (2004) 2.99

Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the mid/distal esophagus: five-year survival of a randomized clinical trial. Ann Surg (2007) 2.78

Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD Initiative. Radiology (2003) 2.73

Prognostic factors in adenocarcinoma of the esophagus or gastroesophageal junction. J Clin Oncol (2006) 2.72

Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Ann Intern Med (2015) 2.71

Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series. Lancet Neurol (2006) 2.67

Treatment of acute posttraumatic stress disorder with brief cognitive behavioral therapy: a randomized controlled trial. Am J Psychiatry (2007) 2.65

Clinical decision rules for excluding pulmonary embolism: a meta-analysis. Ann Intern Med (2011) 2.57

Diagnostic test accuracy may vary with prevalence: implications for evidence-based diagnosis. J Clin Epidemiol (2008) 2.50

In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin. J Immunol (2006) 2.44

Imaging strategies for detection of urgent conditions in patients with acute abdominal pain: diagnostic accuracy study. BMJ (2009) 2.35

Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus. Gastroenterology (2002) 2.19

Antecolic versus retrocolic route of the gastroenteric anastomosis after pancreatoduodenectomy: a randomized controlled trial. Ann Surg (2014) 2.15

Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Clin Chem Lab Med (2003) 2.10

Prevalence and triggers of syncope in medical students. Am J Cardiol (2003) 2.08

Cortisol and post-traumatic stress disorder in adults: systematic review and meta-analysis. Br J Psychiatry (2007) 2.06

Case-control and two-gate designs in diagnostic accuracy studies. Clin Chem (2005) 1.98

Overinterpretation and misreporting of diagnostic accuracy studies: evidence of "spin". Radiology (2013) 1.96

Quality of life in patients with psoriasis: a systematic literature review. J Investig Dermatol Symp Proc (2004) 1.95

Assessing the value of diagnostic tests: a framework for designing and evaluating trials. BMJ (2012) 1.93

Long-term functional outcome and risk factors for recurrence after surgical treatment for low and high perianal fistulas of cryptoglandular origin. Dis Colon Rectum (2008) 1.92

Redarkening of port-wine stains 10 years after pulsed-dye-laser treatment. N Engl J Med (2007) 1.92

Childhood constipation: longitudinal follow-up beyond puberty. Gastroenterology (2003) 1.89

Short- and long-term prognosis after acute myocardial infarction in men versus women. Am J Cardiol (2006) 1.89

Galactomannan detection for invasive aspergillosis in immunocompromized patients. Cochrane Database Syst Rev (2008) 1.88

Effect of starting with hemodialysis compared with peritoneal dialysis in patients new on dialysis treatment: a randomized controlled trial. Kidney Int (2003) 1.87

How good are clinical severity and outcome measures for psoriasis?: quantitative evaluation in a systematic review. J Invest Dermatol (2009) 1.87

Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: systematic review and meta-analysis. BMJ (2013) 1.86

The suitability of quality-of-life questionnaires for psoriasis research: a systematic literature review. Arch Dermatol (2002) 1.84

Colorectal liver metastases: CT, MR imaging, and PET for diagnosis--meta-analysis. Radiology (2005) 1.84

Variables associated with positive findings at relaparotomy in patients with secondary peritonitis. Crit Care Med (2007) 1.80

Lifetime cumulative incidence of syncope in the general population: a study of 549 Dutch subjects aged 35-60 years. J Cardiovasc Electrophysiol (2006) 1.79

Extent and clinical consequences of antibody formation against adalimumab in patients with plaque psoriasis. Arch Dermatol (2010) 1.77

The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. The Standards for Reporting of Diagnostic Accuracy Group. Croat Med J (2003) 1.76

Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS One (2010) 1.73

Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy. J Invest Dermatol (2011) 1.71

Effectiveness of human menopausal gonadotropin versus recombinant follicle-stimulating hormone for controlled ovarian hyperstimulation in assisted reproductive cycles: a meta-analysis. Fertil Steril (2003) 1.71

Therapeutic delay and survival after surgery for cancer of the pancreatic head with or without preoperative biliary drainage. Ann Surg (2010) 1.70

Quality of reporting of diagnostic accuracy studies. Radiology (2005) 1.70

A risk score for unfavorable outcome in adults with bacterial meningitis. Ann Neurol (2008) 1.66

Value of history-taking in syncope patients: in whom to suspect long QT syndrome? Europace (2009) 1.65

Toward complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Acad Radiol (2003) 1.64

Altered penetration of polyethylene glycols into uninvolved skin of atopic dermatitis patients. J Invest Dermatol (2006) 1.62

Effect of clomifene citrate plus metformin and clomifene citrate plus placebo on induction of ovulation in women with newly diagnosed polycystic ovary syndrome: randomised double blind clinical trial. BMJ (2006) 1.61

Preoperative prediction of the occurrence and severity of complications after esophagectomy for cancer with use of a nomogram. Ann Thorac Surg (2008) 1.60

Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks: a randomized controlled trial. PLoS Med (2012) 1.59

Community-acquired bacterial meningitis in older people. J Am Geriatr Soc (2006) 1.59

Serum mesothelin for diagnosing malignant pleural mesothelioma: an individual patient data meta-analysis. J Clin Oncol (2012) 1.59

Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study. BMJ (2006) 1.59

Differences between univariate and bivariate models for summarizing diagnostic accuracy may not be large. J Clin Epidemiol (2009) 1.58

Bias in sensitivity and specificity caused by data-driven selection of optimal cutoff values: mechanisms, magnitude, and solutions. Clin Chem (2008) 1.58

The STARD initiative. Lancet (2003) 1.57

Ultrasonography, computed tomography and magnetic resonance imaging for diagnosis and determining resectability of pancreatic adenocarcinoma: a meta-analysis. J Comput Assist Tomogr (2005) 1.56

Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients. J Invest Dermatol (2009) 1.56

Esophageal cancer: CT, endoscopic US, and FDG PET for assessment of response to neoadjuvant therapy--systematic review. Radiology (2005) 1.56

Publication and reporting of test accuracy studies registered in Clin Chem (2013) 1.55

Loss of TLR2, TLR4, and TLR5 on Langerhans cells abolishes bacterial recognition. J Immunol (2007) 1.55

Computed tomographic colonography compared with colonoscopy in patients at increased risk for colorectal cancer. Gastroenterology (2004) 1.55

Observer variation in MRI evaluation of patients suspected of lumbar disk herniation. AJR Am J Roentgenol (2005) 1.54

Gut-directed hypnotherapy for functional abdominal pain or irritable bowel syndrome in children: a systematic review. Arch Dis Child (2012) 1.54

Cardiovascular consequences of famine in the young. Eur Heart J (2011) 1.53

A systematic review finds that diagnostic reviews fail to incorporate quality despite available tools. J Clin Epidemiol (2005) 1.51

Prediction models in reproductive medicine: a critical appraisal. Hum Reprod Update (2009) 1.50

Beyond diagnostic accuracy: the clinical utility of diagnostic tests. Clin Chem (2012) 1.49

How to adjust for comorbidity in survival studies in ESRD patients: a comparison of different indices. Am J Kidney Dis (2002) 1.49

Validation of a nomogram predicting complications after esophagectomy for cancer. Ann Thorac Surg (2010) 1.47