Published in Nature on August 14, 2003
Breaking the chains: structure and function of the deubiquitinases. Nat Rev Mol Cell Biol (2009) 8.85
Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol (2005) 8.06
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell (2007) 7.10
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem (2009) 6.23
Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev (2009) 4.55
Oncogenic activation of NF-kappaB. Cold Spring Harb Perspect Biol (2010) 3.30
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature (2011) 3.17
Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem J (2004) 3.01
A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. Mol Cell (2009) 2.81
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep (2008) 2.65
NF-κB addiction and its role in cancer: 'one size does not fit all'. Oncogene (2010) 2.56
Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. Mol Cell (2012) 2.51
NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways. Cell (2010) 2.49
Ubiquitination in signaling to and activation of IKK. Immunol Rev (2012) 2.28
Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity. Biochem J (2004) 2.23
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1. EMBO J (2009) 2.17
Protein partners of deubiquitinating enzymes. Biochem J (2008) 2.15
Linear polyubiquitination: a new regulator of NF-kappaB activation. EMBO Rep (2009) 2.15
Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems. PLoS Pathog (2007) 2.14
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses. J Exp Med (2007) 2.14
The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. Nat Immunol (2009) 2.12
TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets. J Clin Invest (2012) 2.10
NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK. Immunity (2011) 2.10
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2. EMBO J (2007) 2.07
Molecular basis of NF-κB signaling. Annu Rev Biophys (2013) 2.03
Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice. J Clin Invest (2006) 2.02
Deubiquitinases in the regulation of NF-κB signaling. Cell Res (2010) 2.00
Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation. Mol Cell (2009) 2.00
Classical and/or alternative NF-kappaB pathway activation in multiple myeloma. Blood (2010) 1.96
Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death. Nat Rev Mol Cell Biol (2013) 1.89
Expanding role of ubiquitination in NF-κB signaling. Cell Res (2010) 1.89
Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases. Endocr Rev (2009) 1.88
Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation. J Exp Med (2005) 1.85
MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling. J Exp Med (2010) 1.84
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways. EMBO Rep (2005) 1.79
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Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD. J Biol Chem (2008) 1.78
The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme. EMBO J (2005) 1.76
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol Cell Biol (2007) 1.76
DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. Immunol Rev (2012) 1.74
Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts. J Immunol (2009) 1.73
The ubiquitin system, disease, and drug discovery. BMC Biochem (2008) 1.73
Regulation of MITF stability by the USP13 deubiquitinase. Nat Commun (2011) 1.62
The tumor suppressor CYLD regulates entry into mitosis. Proc Natl Acad Sci U S A (2007) 1.61
Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation. Mol Cell Biol (2005) 1.61
Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies. Immunol Rev (2012) 1.60
Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells. Proc Natl Acad Sci U S A (2004) 1.59
Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J Exp Med (2009) 1.59
Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8. Mol Cell Biol (2004) 1.54
Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice. J Clin Invest (2008) 1.53
T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1. EMBO J (2011) 1.52
The dark side of EGFP: defective polyubiquitination. PLoS One (2006) 1.49
Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane. Mol Biol Cell (2008) 1.48
Emerging roles for the non-canonical IKKs in cancer. Oncogene (2010) 1.48
Signal processing by its coil zipper domain activates IKK gamma. Proc Natl Acad Sci U S A (2008) 1.46
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nat Immunol (2012) 1.45
The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. J Exp Med (2003) 1.44
The IkappaB kinase complex: master regulator of NF-kappaB signaling. Immunol Res (2008) 1.43
Regulation of catalytic activities of HECT ubiquitin ligases. Biochem Biophys Res Commun (2007) 1.42
Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin. Proc Natl Acad Sci U S A (2008) 1.42
Optineurin regulates the interferon response in a cell cycle-dependent manner. PLoS Pathog (2015) 1.42
Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A. J Cell Biol (2005) 1.41
IKK biology. Immunol Rev (2012) 1.40
Polyubiquitin binding and disassembly by deubiquitinating enzymes. Chem Rev (2009) 1.36
A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage. Mol Cell Biol (2011) 1.36
Reverse the curse--the role of deubiquitination in cell cycle control. Curr Opin Cell Biol (2008) 1.31
Screening of DUB activity and specificity by MALDI-TOF mass spectrometry. Nat Commun (2014) 1.31
WIP1 phosphatase is a negative regulator of NF-kappaB signalling. Nat Cell Biol (2009) 1.30
Tumor mapping in 2 large multigenerational families with CYLD mutations: implications for disease management and tumor induction. Arch Dermatol (2009) 1.28
The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity. J Immunol (2009) 1.26
Targeting the ubiquitin-proteasome system for cancer therapy. Cancer Sci (2008) 1.24
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes. Cell Rep (2015) 1.23
The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X. Traffic (2008) 1.22
Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. PLoS One (2007) 1.22
A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med (2009) 1.22
TRAF molecules in cell signaling and in human diseases. J Mol Signal (2013) 1.22
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin. EMBO J (2009) 1.21
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling. J Virol (2011) 1.21
Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development. Oncogene (2010) 1.21
The Drosophila IMD pathway in the activation of the humoral immune response. Dev Comp Immunol (2013) 1.21
The BRG1- and hBRM-associated factor BAF57 induces apoptosis by stimulating expression of the cylindromatosis tumor suppressor gene. Mol Cell Biol (2005) 1.20
Ubiquitin in NF-kappaB signaling. Chem Rev (2009) 1.20
WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex. J Biol Chem (2010) 1.20
CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt. Nat Commun (2012) 1.18
Regulation of NF-κB by ubiquitination. Curr Opin Immunol (2013) 1.17
Deubiquitylating enzymes and disease. BMC Biochem (2008) 1.17
miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops. Cell Res (2012) 1.17
Evolution of peptidase diversity. J Biol Chem (2008) 1.16
Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response. PLoS Pathog (2013) 1.15
The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol (2011) 1.14
USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity. J Biol Chem (2009) 1.14
Emerging therapies targeting the ubiquitin proteasome system in cancer. J Clin Invest (2014) 1.13
Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin. J Biol Chem (2009) 1.13
Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling. J Biol Chem (2008) 1.12
Inhibition of the NF-kappaB pathway by varicella-zoster virus in vitro and in human epidermal cells in vivo. J Virol (2006) 1.12
Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity. Mol Cell Biol (2006) 1.10
NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress. Mol Cell (2011) 1.09
Update of cylindromatosis gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling. Hum Mutat (2009) 1.09
MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme. Cell Death Dis (2012) 1.09
Epstein-Barr virus activates beta-catenin in type III latently infected B lymphocyte lines: association with deubiquitinating enzymes. Proc Natl Acad Sci U S A (2003) 1.08
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx. Nature (2011) 9.30
Suppression of microRNA-silencing pathway by HIV-1 during virus replication. Science (2007) 5.07
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature (2002) 3.21
The CD95 receptor: apoptosis revisited. Cell (2007) 3.13
Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol (2004) 3.09
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells. Retrovirology (2012) 2.92
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Cell Host Microbe (2012) 2.66
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity (2012) 2.58
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency. Nat Immunol (2012) 2.38
Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency. EMBO J (2007) 2.37
RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity (2011) 2.29
Mature T cells depend on signaling through the IKK complex. Immunity (2003) 2.21
X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. J Exp Med (2006) 2.18
Hsp90 recognizes a common surface on client kinases. J Biol Chem (2006) 2.12
NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain. EMBO J (2009) 2.07
Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep (2012) 2.06
Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity (2004) 1.99
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency. J Clin Invest (2003) 1.92
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J Immunol (2008) 1.90
A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter. Nat Cell Biol (2003) 1.82
Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor. J Cell Biol (2004) 1.79
The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation. PLoS Biol (2010) 1.77
Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains. EMBO Rep (2006) 1.72
Caspase-8 is involved in neovascularization-promoting progenitor cell functions. Arterioscler Thromb Vasc Biol (2009) 1.70
Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2. Nat Cell Biol (2007) 1.70
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med (2009) 1.69
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases. J Exp Med (2004) 1.67
The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms. Mol Cell (2007) 1.56
NF-kappaB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling. Mol Cell Biol (2006) 1.51
Intraoperative airway obstruction related to tracheostomy tube malposition in a patient with achondroplasia and Jeune's syndrome. Middle East J Anaesthesiol (2010) 1.44
NEMO trimerizes through its coiled-coil C-terminal domain. J Biol Chem (2002) 1.41
From calcium to NF-kappa B signaling pathways in neurons. Mol Cell Biol (2003) 1.38
Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. Cancer Res (2006) 1.37
Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation. Hum Mol Genet (2004) 1.37
The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes. Hum Mol Genet (2002) 1.36
AIP4/Itch regulates Notch receptor degradation in the absence of ligand. PLoS One (2008) 1.35
Down-regulating constitutive activation of the NF-kappaB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis. Blood (2005) 1.34
Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell lines. J Biol Chem (2003) 1.34
Forebrain-specific neuronal inhibition of nuclear factor-kappaB activity leads to loss of neuroprotection. J Neurosci (2003) 1.28
Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene (2003) 1.28
Negative feedback loop in T cell activation through IkappaB kinase-induced phosphorylation and degradation of Bcl10. Proc Natl Acad Sci U S A (2007) 1.28
Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti. Hum Mol Genet (2007) 1.25
Posttranslational modifications of NEMO and its partners in NF-kappaB signaling. Trends Cell Biol (2006) 1.22
Osteopetrosis, lymphedema, anhidrotic ectodermal dysplasia, and immunodeficiency in a boy and incontinentia pigmenti in his mother. Pediatrics (2002) 1.21
T-cell-receptor- and B-cell-receptor-mediated activation of NF-kappaB in lymphocytes. Curr Opin Immunol (2004) 1.19
Induction of the NF-kappaB cascade by recruitment of the scaffold molecule NEMO to the T cell receptor. Immunity (2003) 1.18
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO-IKK supramolecular structures. J Cell Biol (2014) 1.17
Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels. Nat Struct Mol Biol (2011) 1.16
The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration. J Biol Chem (2004) 1.15
Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology (2007) 1.15
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses. EMBO J (2005) 1.14
The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity. Proc Natl Acad Sci U S A (2008) 1.13
Hijacking of host cell IKK signalosomes by the transforming parasite Theileria. Science (2002) 1.13
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol Cell Biol (2006) 1.12
The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains. J Biol Chem (2004) 1.11
Visualization of lymphatic vessels through NF-kappaB activity. Blood (2004) 1.10
NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. J Immunol (2006) 1.10
NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein. PLoS Pathog (2009) 1.08
Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med (2007) 1.07
ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo. J Immunol (2006) 1.06
Concepts of tissue injury and cell death in inflammation: a historical perspective. Nat Rev Immunol (2013) 1.05
Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression. J Biol Chem (2007) 1.05
The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile. Nutr J (2008) 1.04
Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression. Mol Cell (2012) 1.02
DARPin-assisted crystallography of the CC2-LZ domain of NEMO reveals a coupling between dimerization and ubiquitin binding. J Mol Biol (2009) 1.02
Listeriolysin O secreted by Listeria monocytogenes induces NF-kappaB signalling by activating the IkappaB kinase complex. Mol Microbiol (2002) 1.01
NF-kappaB and inflammation in genetic disease. Biochem Pharmacol (2006) 0.98
How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family. Arthritis Res (2002) 0.96
Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization. J Biol Chem (2004) 0.95
IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival. Proc Natl Acad Sci U S A (2003) 0.95
Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in Yersinia enterocolitica-infected cells. J Immunol (2005) 0.95
Transcription-controlled gene therapy against tumor angiogenesis. J Clin Invest (2004) 0.94
The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation. J Biol Chem (2012) 0.94
Inhibition of IkappaB kinase subunit 2 in cutaneous T-cell lymphoma down-regulates nuclear factor-kappaB constitutive activation, induces cell death, and potentiates the apoptotic response to antineoplastic chemotherapeutic agents. Clin Cancer Res (2008) 0.93
Dominant negative MORT1/FADD rescues mice from CD95 and TNF-induced liver failure. Hepatology (2003) 0.93
If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation. Mol Cell (2006) 0.91
IKK regulation and human genetics. Curr Top Microbiol Immunol (2011) 0.91
Sleep deprivation increases the activation of nuclear factor kappa B in lateral hypothalamic cells. Brain Res (2004) 0.90
Expression of Ca(2+)-independent and Ca(2+)-dependent phospholipases A(2) and cyclooxygenases in human melanocytes and malignant melanoma cell lines. Biochim Biophys Acta (2008) 0.90
Identification of a new NEMO/TRAF6 interface affected in incontinentia pigmenti pathology. Hum Mol Genet (2010) 0.90
TRAIL is expressed in the brain cells of Alzheimer's disease patients. Neuroreport (2004) 0.89
Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals. J Cell Sci (2013) 0.88
Homozygosity mapping of a locus for a novel syndromic ichthyosis to chromosome 3q27-q28. J Invest Dermatol (2002) 0.87
"Without Ub I am nothing": NEMO as a multifunctional player in ubiquitin-mediated control of NF-kappaB activation. Cell Mol Life Sci (2010) 0.87
The adaptor-associated kinase 1, AAK1, is a positive regulator of the Notch pathway. J Biol Chem (2011) 0.87
Combined deficiency in IkappaBalpha and IkappaBepsilon reveals a critical window of NF-kappaB activity in natural killer cell differentiation. Blood (2004) 0.85
Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation. J Interferon Cytokine Res (2006) 0.85
Signal transduction: A regulator branches out. Nature (2003) 0.84
Inducible expression and pathophysiologic functions of T-plastin in cutaneous T-cell lymphoma. Blood (2012) 0.84
The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors. FASEB J (2013) 0.84
Arachidonic acid differentially affects basal and lipopolysaccharide-induced sPLA(2)-IIA expression in alveolar macrophages through NF-kappaB and PPAR-gamma-dependent pathways. Mol Pharmacol (2002) 0.82