Christopher A Klebanoff

Author PubWeight™ 60.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells. J Exp Med 2003 11.08
2 Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells. J Exp Med 2005 8.13
3 Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells. J Clin Invest 2005 7.01
4 CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells. J Immunol 2005 6.95
5 IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy. Blood 2008 3.52
6 Paths to stemness: building the ultimate antitumour T cell. Nat Rev Cancer 2012 2.79
7 Th17 cells are long lived and retain a stem cell-like molecular signature. Immunity 2011 2.64
8 Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function. J Clin Invest 2013 2.50
9 BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Nature 2013 2.36
10 Vaccine-stimulated, adoptively transferred CD8+ T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction. J Immunol 2004 2.22
11 Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proc Natl Acad Sci U S A 2008 2.07
12 Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy. Blood 2010 2.01
13 Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells. Nat Immunol 2011 1.51
14 Interleukin-2-dependent mechanisms of tolerance and immunity in vivo. J Immunol 2006 1.43
15 Pharmacologic induction of CD8+ T cell memory: better living through chemistry. Sci Transl Med 2009 1.34
16 Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer. J Leukoc Biol 2004 1.12
17 Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies. J Immunother 2011 1.04
18 Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy. J Clin Invest 2015 0.96
19 Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood 2013 0.85
20 The transcription factor BACH2 promotes tumor immunosuppression. J Clin Invest 2016 0.78