Published in J Agric Food Chem on August 27, 2003
The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci (2006) 6.86
Aryl hydrocarbon receptor ligands in cancer: friend and foe. Nat Rev Cancer (2014) 1.46
Biomonitoring and biomarkers: exposure assessment will never be the same. Environ Health Perspect (2006) 1.15
Herbal product-drug interactions mediated by induction. Br J Clin Pharmacol (2006) 1.00
Third-generation Ah receptor-responsive luciferase reporter plasmids: amplification of dioxin-responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicol Sci (2011) 0.95
Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7. BMC Pharmacol (2007) 0.93
The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation. Chem Res Toxicol (2011) 0.93
Newspapers and newspaper ink contain agonists for the ah receptor. Toxicol Sci (2008) 0.86
Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. PLoS One (2013) 0.86
Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh. Clin Pharmacol Ther (2009) 0.86
Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation. Drug Metab Dispos (2015) 0.83
Tryptophan Feeding of the IDO1-AhR Axis in Host-Microbial Symbiosis. Front Immunol (2014) 0.80
Taking nutritional supplements for three months reduced blood pressure but not blood lipid levels in students. J Chiropr Med (2006) 0.79
Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes. Drug Metab Dispos (2015) 0.79
An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement. PLoS Genet (2014) 0.79
Role of Aryl Hydrocarbon Receptor in Circadian Clock Disruption and Metabolic Dysfunction. Environ Health Insights (2016) 0.79
In vitro System for Assessing Dioxin Absorption by Intestinal Epithelial Cells and for Preventing this Absorption by Food Substances. Cytotechnology (2005) 0.78
Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway. Chem Res Toxicol (2015) 0.77
The aryl hydrocarbon receptor regulates an essential transcriptional element in the immunoglobulin heavy chain gene. Cell Immunol (2015) 0.76
Induction of cytochrome P450 1A by cow milk-based formula: a comparative study between human milk and formula. Br J Pharmacol (2005) 0.76
Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits. Environ Sci Technol (2015) 0.75
The effect of fruit and vegetable powder mix on hypertensive subjects: a pilot study. J Chiropr Med (2009) 0.75
Ligand activation of the Ah receptor contributes to gastrointestinal homeostasis. Curr Opin Toxicol (2017) 0.75
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (2010) 5.50
In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. Toxicol Sci (2006) 1.87
In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environ Health Perspect (2008) 1.82
Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood (2008) 1.78
Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish. Environ Sci Technol (2008) 1.61
Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Mol Pharmacol (2007) 1.43
Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. Biochemistry (2007) 1.41
Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. Toxicol Sci (2002) 1.40
CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. Toxicol Sci (2010) 1.31
Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Biofactors (2004) 1.27
Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. Toxicol Sci (2004) 1.24
Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. Biochemistry (2009) 1.23
Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). Mol Nutr Food Res (2008) 1.23
Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. Am J Respir Cell Mol Biol (2010) 1.22
Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB. J Biol Chem (2013) 1.21
Neutral sphingomyelinase 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death. Am J Physiol Lung Cell Mol Physiol (2009) 1.20
Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect (2009) 1.19
Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of ah receptor agonists. Toxicol Sci (2002) 1.18
Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. J Clin Endocrinol Metab (2002) 1.16
Chromatographic analysis of endogenous retinoids in tissues and serum. Anal Biochem (2003) 1.14
Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities. Toxicol Sci (2005) 1.07
Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results. Environ Sci Technol (2005) 1.06
Are brominated flame retardants endocrine disruptors? Environ Int (2003) 1.04
Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. Environ Sci Technol (2008) 1.03
Identification of estrogenic compounds in fish bile using bioassay-directed fractionation. Environ Sci Technol (2004) 1.03
The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression. Arch Biochem Biophys (2002) 1.01
Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor. J Biol Chem (2008) 1.01
Persistent binding of ligands to the aryl hydrocarbon receptor. Toxicol Sci (2007) 0.99
Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. Biosci Biotechnol Biochem (2002) 0.98
Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. J Invest Dermatol (2013) 0.96
Third-generation Ah receptor-responsive luciferase reporter plasmids: amplification of dioxin-responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicol Sci (2011) 0.95
In vitro antiestrogenic effects of aryl methyl sulfone metabolites of polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene on 17beta-estradiol-induced gene expression in several bioassay systems. Toxicol Sci (2002) 0.95
New aryl hydrocarbon receptor homology model targeted to improve docking reliability. J Chem Inf Model (2011) 0.94
Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci (2004) 0.94
Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed mutagenesis. Mol Cell Biol (2014) 0.94
Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor. Biochemistry (2013) 0.93
The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation. Chem Res Toxicol (2011) 0.93
Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry (2002) 0.93
Analysis of the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human ovarian carcinoma BG-1 cells. Mol Pharmacol (2002) 0.92
Late infective endocarditis of an atrial septal occluder device presenting as a cystic mass. Echocardiography (2011) 0.91
Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays. Environ Sci Technol (2008) 0.91
Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. Environ Sci Technol (2002) 0.91
Developmental exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107): long-term effects on brain development, behavior, and brain stem auditory evoked potentials in rats. Toxicol Sci (2004) 0.90
Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domain. J Biol Chem (2011) 0.89
Nitric oxide-enhanced caspase-3 and acidic sphingomyelinase interaction: a novel mechanism by which airway epithelial cells escape ceramide-induced apoptosis. Exp Cell Res (2006) 0.89
Gas-phase ambient air contaminants exhibit significant dioxin-like and estrogen-like activity in vitro. Environ Health Perspect (2006) 0.88
Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon receptor agonists present in tire extracts. Environ Toxicol Chem (2011) 0.88
Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border. Environ Health Perspect (2003) 0.88
Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: normalization of superinduction results for improved sample potency estimation. Talanta (2010) 0.88
Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. J Biochem Mol Toxicol (2006) 0.87
Estrogenic and dioxin-like compounds in sediment from Zierikzee harbour identified with CALUX assay-directed fractionation combined with one and two dimensional gas chromatography analyses. Chemosphere (2006) 0.87
Effects of in utero exposure to 4-hydroxy-2,3,3',4',5-pentachlorobiphenyl (4-OH-CB107) on developmental landmarks, steroid hormone levels, and female estrous cyclicity in rats. Toxicol Sci (2004) 0.87
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription. Am J Respir Cell Mol Biol (2010) 0.86
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays. Environ Sci Technol (2013) 0.86
Newspapers and newspaper ink contain agonists for the ah receptor. Toxicol Sci (2008) 0.86
A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein. Carcinogenesis (2012) 0.86
Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays. Sci Total Environ (2002) 0.86
Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds. Toxicol Sci (2013) 0.86
Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. PLoS One (2013) 0.86
Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. PLoS One (2013) 0.86
Adherence to monthly online self-assessments for short-term monitoring: a 1-year study in relapsing-remitting multiple sclerosis patients after start of disease modifying treatment. Patient Prefer Adherence (2013) 0.86
Comparative gene responses to collected ambient particles in vitro: endothelial responses. Physiol Genomics (2011) 0.84
Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food Chem Toxicol (2011) 0.83
Screening of dioxin-like toxicity equivalents for various matrices with wildtype and recombinant rat hepatoma H4IIE cells. Toxicol Sci (2002) 0.83
Synthesis and estrogen receptor affinity of a 4-hydroxytamoxifen-labeled ligand for diagnostic imaging. Bioorg Med Chem (2002) 0.83
Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. Am J Physiol Endocrinol Metab (2008) 0.82
Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms. Chem Biol Interact (2005) 0.82
Toxicological profiling of sediments using in vitro bioassays, with emphasis on endocrine disruption. Environ Toxicol Chem (2004) 0.82
Analysis of Ah receptor pathway activation by brominated flame retardants. Chemosphere (2004) 0.82
Endocrine effects of polycyclic musks: do we smell a rat? Int J Androl (2007) 0.81
The CALUX bio-assay: analytical comparison between mouse hepatoma cell lines with a low (H1L6.1c3) and high (H1L7.5c1) number of dioxin response elements. Talanta (2011) 0.81
Dioxin-like exposures and effects on estrogenic and androgenic exposures and micronuclei frequency in mother-newborn pairs. Environ Int (2010) 0.81
Biomonitoring of estrogenic exposure and identification of responsible compounds in bream from Dutch surface waters. Environ Toxicol Chem (2007) 0.81
Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor. Toxicol Sci (2007) 0.81
Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol. Toxicol Lett (2011) 0.81
Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons. Environ Toxicol Chem (2002) 0.81
Estrogenic and androgenic activities in total plasma measured with reporter-gene bioassays: relevant exposure measures for endocrine disruptors in epidemiologic studies? Environ Int (2011) 0.81
Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicol Lett (2013) 0.80
Characterization and potential environmental risks of leachate from shredded rubber mulches. Chemosphere (2009) 0.80
In vitro characterization of the effectiveness of enhanced sewage treatment processes to eliminate endocrine activity of hospital effluents. Water Res (2012) 0.80
Maternal diet and dioxin-like activity, bulky DNA adducts and micronuclei in mother-newborns. Mutat Res (2012) 0.79
Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development. Toxicol Sci (2010) 0.79
Biological validation of a sample preparation method for ER-CALUX bioanalysis of estrogenic activity in sediment using mixtures of xeno-estrogens. Environ Sci Technol (2006) 0.79
Biological measurement of estrogenic activity in urine and bile conjugates with the in vitro ER-CALUX reporter gene assay. Environ Toxicol Chem (2002) 0.79
Mathematical model developed for environmental samples: prediction of GC/MS dioxin TEQ from XDS-CALUX bioassay data. Environ Sci Technol (2007) 0.79
The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environ Toxicol Chem (2012) 0.79
Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2). Arch Toxicol (2014) 0.78
Chemicals having estrogenic activity can be released from some bisphenol A-free, hard and clear, thermoplastic resins. Environ Health (2014) 0.78
Specificity of nuclear protein binding to a CYP1A1 negative regulatory element. Biochem Biophys Res Commun (2002) 0.78
Detection of xenoestrogens in serum after immunoprecipitation of endogenous steroidal estrogens. Environ Health Perspect (2002) 0.78
Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis. Biochemistry (2013) 0.78
Effect based monitoring of seasonal ambient air exposures in Australia sampled by PUF passive air samplers. Atmos Pollut Res (2010) 0.78
Atmospheric concentrations of polybrominated diphenyl ethers at near-source sites. Environ Sci Technol (2007) 0.78
Analysis of dioxins in contaminated soils with the calux and caflux bioassays, an immunoassay, and gas chromatography/high-resolution mass spectrometry. Environ Toxicol Chem (2007) 0.78
Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicol Lett (2013) 0.77
Dietary red clover (Trifolium pratense) induces oviduct growth and decreases ovary and testes growth in Japanese quail chicks. Reprod Toxicol (2008) 0.77
Sample preparation method for the ER-CALUX bioassay screening of (xeno-)estrogenic activity in sediment extracts. Sci Total Environ (2007) 0.77
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context. Toxicology (2012) 0.77
Reduction of vitellogenin synthesis by an aryl hydrocarbon receptor agonist in the white sturgeon (Acipenser transmontamus). Environ Toxicol Chem (2009) 0.77