Published in Cardiovasc Drug Rev on January 01, 2003
Literature mining for the discovery of hidden connections between drugs, genes and diseases. PLoS Comput Biol (2010) 1.77
Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin. Br J Clin Pharmacol (2005) 0.89
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Molecular mechanisms underlying the effects of statins in the central nervous system. Int J Mol Sci (2014) 0.83
Atherosclerosis: current status of prevention and treatment. Int J Angiol (2011) 0.82
Pitavastatin: evidence for its place in treatment of hypercholesterolemia. Core Evid (2010) 0.81
Pitavastatin suppressed liver cancer cells in vitro and in vivo. Onco Targets Ther (2016) 0.75
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet (2007) 9.56
A new method for large scale isolation of kidney glomeruli from mice. Am J Pathol (2002) 4.63
IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am J Respir Crit Care Med (2008) 2.62
CSF hypocretin-1 (orexin-A) concentrations in narcolepsy with and without cataplexy and idiopathic hypersomnia. J Sleep Res (2002) 2.60
Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke Trial. Stroke (2005) 2.56
Development and characterization of IL-21-producing CD4+ T cells. J Exp Med (2008) 2.34
Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization. Circ Res (2006) 2.31
Total sleep deprivation elevates blood pressure through arterial baroreflex resetting: a study with microneurographic technique. Sleep (2003) 2.17
IL-25 enhances allergic airway inflammation by amplifying a TH2 cell-dependent pathway in mice. J Allergy Clin Immunol (2006) 2.16
Preventive effects of eicosapentaenoic acid on coronary artery disease in patients with peripheral artery disease. Circ J (2010) 2.13
Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease. Circ J (2009) 2.01
Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activation. Blood (2003) 1.95
Selective granulocyte and monocyte adsorptive apheresis as a first-line treatment for steroid naïve patients with active ulcerative colitis: a prospective uncontrolled study. Dig Dis Sci (2004) 1.92
Is the diagnosis of metabolic syndrome useful for predicting cardiovascular disease in asian diabetic patients? Analysis from the Japan Diabetes Complications Study. Diabetes Care (2005) 1.85
The long-term effects of self-management education for patients with type 2 diabetes on glycemic control: response to Norris et al. Diabetes Care (2002) 1.78
Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study). Diabetes Care (2002) 1.70
CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration. Arterioscler Thromb Vasc Biol (2010) 1.60
Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy. Biochem Biophys Res Commun (2003) 1.55
Feasibility and safety of granulocyte colony-stimulating factor treatment in patients with acute myocardial infarction. Int J Cardiol (2006) 1.52
Zoledronate has an antitumor effect and induces actin rearrangement in dexamethasone-resistant myeloma cells. Eur J Haematol (2007) 1.52
Prevalence of metabolic syndrome in the general Japanese population in 2000. J Atheroscler Thromb (2006) 1.50
Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line C(epsilon) transcription of IL-4-stimulated B cells. Blood (2002) 1.50
Bisphenol A affects glucose transport in mouse 3T3-F442A adipocytes. Br J Pharmacol (2004) 1.46
Percutaneous coronary intervention plus medical therapy reduces the incidence of acute coronary syndrome more effectively than initial medical therapy only among patients with low-risk coronary artery disease a randomized, comparative, multicenter study. JACC Cardiovasc Interv (2008) 1.45
Involvement of TNF receptor-associated factor 6 in IL-25 receptor signaling. J Immunol (2006) 1.36
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies. Mol Cancer Res (2003) 1.32
Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia. Circ Cardiovasc Interv (2009) 1.30
Adacolumn for selective leukocytapheresis as a non-pharmacological treatment for patients with disorders of the immune system: an adjunct or an alternative to drug therapy? J Clin Apher (2005) 1.30
Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial. Stroke (2008) 1.29
Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS). Atherosclerosis (2009) 1.28
The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells. J Atheroscler Thromb (2002) 1.20
Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator. Arthritis Rheum (2008) 1.18
Targeted disruption of TGF-beta-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury. Circ Res (2005) 1.18
Analysis of the global RNA expression profiles of skeletal muscle cells treated with statins. J Atheroscler Thromb (2005) 1.18
Report of the Japan Atherosclerosis Society (JAS) Guideline for Diagnosis and Treatment of Hyperlipidemia in Japanese adults. J Atheroscler Thromb (2002) 1.17
CD4(+)CD25(+) T-cell development is regulated by at least 2 distinct mechanisms. Blood (2002) 1.16
Dysadipocytokinemia in werner syndrome and its recovery by treatment with pioglitazone. Diabetes Care (2004) 1.14
Advanced glycation end products attenuate cellular insulin sensitivity by increasing the generation of intracellular reactive oxygen species in adipocytes. Diabetes Res Clin Pract (2006) 1.13
Relationships between plasma fatty acid composition and coronary artery disease. J Atheroscler Thromb (2010) 1.11
T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways. J Allergy Clin Immunol (2007) 1.09
High glucose-induced upregulation of osteopontin is mediated via Rho/Rho kinase pathway in cultured rat aortic smooth muscle cells. Arterioscler Thromb Vasc Biol (2003) 1.08
Methylation silencing of the Apaf-1 gene in acute leukemia. Mol Cancer Res (2005) 1.07
Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-gamma production and the induction of Th1 cell differentiation. Blood (2007) 1.05
Serum lipid survey and its recent trend in the general Japanese population in 2000. J Atheroscler Thromb (2005) 1.03
IL-4-Stat6 signaling induces tristetraprolin expression and inhibits TNF-alpha production in mast cells. J Exp Med (2003) 1.03
Stat5a inhibits IL-12-induced Th1 cell differentiation through the induction of suppressor of cytokine signaling 3 expression. J Immunol (2005) 1.02
Toward the realization of a better aged society: messages from gerontology and geriatrics. Geriatr Gerontol Int (2012) 1.02
A retrospective search for predictors of clinical response to selective granulocyte and monocyte apheresis in patients with ulcerative colitis. Dig Dis Sci (2006) 1.02
Non-HDL cholesterol as a measure of atherosclerotic risk. J Atheroscler Thromb (2004) 1.01
Clinical features of familial hypercholesterolemia in Japan in a database from 1996-1998 by the research committee of the ministry of health, labour and welfare of Japan. J Atheroscler Thromb (2004) 1.00
Ischemic preconditioning and morphine attenuate myocardial apoptosis and infarction after ischemia-reperfusion in rabbits: role of delta-opioid receptor. Am J Physiol Heart Circ Physiol (2004) 0.99
Global analysis of RNA expression profile in human vascular cells treated with statins. J Atheroscler Thromb (2004) 0.99
Fc receptor-independent development of autoimmune glomerulonephritis in lupus-prone MRL/lpr mice. Arthritis Rheum (2003) 0.99
Proteolytic processing of Stat6 signaling in mast cells as a negative regulatory mechanism. J Exp Med (2002) 0.98
Hyperglycemia-induced alteration of vascular smooth muscle phenotype. J Diabetes Complications (2002) 0.98
Association of cytosine-adenine repeat polymorphism of the estrogen receptor-beta gene with menopausal symptoms. Gend Med (2005) 0.97
LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration. Circ Res (2004) 0.97
Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation. J Immunol (2008) 0.97
Roles of degree of fat deposition and its localization on VEGF expression in adipocytes. Am J Physiol Endocrinol Metab (2004) 0.97
A secreted soluble form of LR11, specifically expressed in intimal smooth muscle cells, accelerates formation of lipid-laden macrophages. Arterioscler Thromb Vasc Biol (2007) 0.96
Increased circulating malondialdehyde-modified LDL levels in patients with coronary artery diseases and their association with peak sizes of LDL particles. Arterioscler Thromb Vasc Biol (2002) 0.96
Indispensable role of Stat5a in Stat6-independent Th2 cell differentiation and allergic airway inflammation. J Immunol (2005) 0.95
Sustained reduction of serum cholesterol in low-dose 6-year simvastatin treatment with minimum side effects in 51,321 Japanese hypercholesterolemic patients. Circ J (2003) 0.95
Revascularization determines volume retention and gene expression by fat grafts in mice. Exp Biol Med (Maywood) (2005) 0.95
Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects. Psychiatry Clin Neurosci (2002) 0.94
Diazepam reduces both arterial blood pressure and muscle sympathetic nerve activity in human. Neurosci Lett (2004) 0.94
The roles of transforming growth factor-β and Smad3 signaling in adipocyte differentiation and obesity. Biochem Biophys Res Commun (2011) 0.93
A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5. J Cell Biol (2004) 0.93
Long-term probucol treatment prevents secondary cardiovascular events: a cohort study of patients with heterozygous familial hypercholesterolemia in Japan. J Atheroscler Thromb (2008) 0.92
Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs. Dev Biol (2003) 0.92
Effect of PPARalpha activation of macrophages on the secretion of inflammatory cytokines in cultured adipocytes. Eur J Pharmacol (2007) 0.91
Pharmacogenetics of HMG-CoA reductase inhibitors: exploring the potential for genotype-based individualization of coronary heart disease management. Atherosclerosis (2004) 0.91
Emergence of fibrocytes showing morphological changes in the inflamed colonic mucosa. Dig Dis Sci (2009) 0.91
Aquaporin 1 is required for hypoxia-inducible angiogenesis in human retinal vascular endothelial cells. Microvasc Res (2008) 0.90
Age dependence of early symptomatic vertebral fracture with high-dose glucocorticoid treatment for collagen vascular diseases. J Clin Endocrinol Metab (2009) 0.89
Hypercholesterolemia associated with splice-junction variation of inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4) gene. J Hum Genet (2003) 0.89
Butyrate reduces colonic paracellular permeability by enhancing PPARgamma activation. Biochem Biophys Res Commun (2002) 0.89
Efficacy and safety of TAK-085 compared with eicosapentaenoic acid in Japanese subjects with hypertriglyceridemia undergoing lifestyle modification: the omega-3 fatty acids randomized double-blind (ORD) study. J Clin Lipidol (2013) 0.89
Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice. J Clin Invest (2008) 0.89
Influence of statins on glucose tolerance in patients with type 2 diabetes mellitus: subanalysis of the collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). J Atheroscler Thromb (2009) 0.89
Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers. Exp Cell Res (2004) 0.89
Pitavastatin: efficacy and safety in intensive lipid lowering. Expert Opin Pharmacother (2007) 0.88
High fat intake induces a population of adipocytes to co-express TLR2 and TNFalpha in mice with insulin resistance. Biochem Biophys Res Commun (2007) 0.88
LRP1B attenuates the migration of smooth muscle cells by reducing membrane localization of urokinase and PDGF receptors. Arterioscler Thromb Vasc Biol (2004) 0.88
Influence of C-peptide on early glomerular changes in diabetic mice. Diabetes Metab Res Rev (2006) 0.88
Epstein-Barr virus-associated primary central nervous system lymphoma in the Japanese population. Neurol Med Chir (Tokyo) (2010) 0.88
Proposed guidelines for hypertriglyceridemia in Japan with non-HDL cholesterol as the second target. J Atheroscler Thromb (2008) 0.88
Leptin deficiency enhances myocardial necrosis and lethality in a murine model of viral myocarditis. Life Sci (2004) 0.87
Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice. J Immunol (2003) 0.87
Increased urinary levels of CXCL5, CXCL8 and CXCL9 in patients with Type 2 diabetic nephropathy. J Diabetes Complications (2008) 0.87
Increased levels of soluble LR11 in cerebrospinal fluid of patients with Alzheimer disease. Dement Geriatr Cogn Disord (2010) 0.86
A functional polymorphism in B and T lymphocyte attenuator is associated with susceptibility to rheumatoid arthritis. Clin Dev Immunol (2011) 0.86
Activation-induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4+ T cells. J Leukoc Biol (2009) 0.86
Colestimide reduces blood polychlorinated biphenyl (PCB) levels. Intern Med (2006) 0.86