Ten statements on the motivation of medical teachers to teach.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 1293453)

Published in Med Teach on January 01, 1992

Authors

C Schormair1, U Swietlik, U Hofmann, S Wilm, L Witte

Author Affiliations

1: Klinikum der Universitaet Muenster, Westfaelische Wilhelms University of Muenster, Germany.

Articles by these authors

(truncated to the top 100)

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med (2001) 9.53

Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood (2000) 9.24

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors. Cancer Res (1999) 4.20

Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells. Circ Res (2001) 3.30

Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J Exp Med (2001) 3.25

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver. Pharmacogenetics (2001) 3.05

A comprehensive guide for the recognition and classification of distinct stages of hair follicle morphogenesis. J Invest Dermatol (1999) 2.92

Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest (2000) 2.08

Immunoenzymometric assay of human glycogen phosphorylase isoenzyme BB in diagnosis of ischemic myocardial injury. Clin Chem (1995) 2.03

Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc Natl Acad Sci U S A (2001) 1.90

Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase. J Biol Chem (2000) 1.89

Focal hyperhidrosis: effective treatment with intracutaneous botulinum toxin. Arch Dermatol (1998) 1.83

Gabapentin enhances the analgesic effect of morphine in healthy volunteers. Anesth Analg (2000) 1.71

Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias. Blood (1996) 1.70

Four new bioactive manzamine-type alkaloids from the Philippine marine sponge Xestospongia ashmorica. J Nat Prod (1996) 1.70

STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells. Proc Natl Acad Sci U S A (1994) 1.67

UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo. Clin Pharmacol Ther (2009) 1.67

VEGF deprivation-induced apoptosis is a component of programmed capillary regression. Development (1999) 1.60

Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells. Proc Natl Acad Sci U S A (1995) 1.52

Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs. Proc Natl Acad Sci U S A (1997) 1.41

Qualitative and Quantitative Analysis of the Phenolic Constituents from Orthosiphon aristatus. Planta Med (1991) 1.38

Alkaline phosphatase activity and localization during the murine hair cycle. Br J Dermatol (1994) 1.34

Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity. Leukemia (2003) 1.32

Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165. J Biol Chem (1999) 1.28

Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma. J Immunother (2000) 1.27

Generation and cyclic remodeling of the hair follicle immune system in mice. J Invest Dermatol (1998) 1.22

Identification of the residues in the extracellular region of KDR important for interaction with vascular endothelial growth factor and neutralizing anti-KDR antibodies. J Biol Chem (2000) 1.21

Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library. Cancer Res (1998) 1.20

Antibiotic and cytotoxic activity of brominated compounds from the marine sponge Verongia aerophoba. Z Naturforsch C (1994) 1.18

Chemical and physical characterization of four interfacial-active rhamnolipids from Pseudomonas spec. DSM 2874 grown on n-alkanes. Z Naturforsch C (1985) 1.18

Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells. Cancer Res (1991) 1.14

Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basic fibroblast growth factor-induced angiogenesis in vivo and in vitro. J Pharmacol Exp Ther (2001) 1.13

Phosphorus-31 nuclear magnetic resonance investigation of the in vivo regulation of intracellular pH in cell suspension cultures of Nicotiana tabacum: the effects of oxygen supply, nitrogen, and external pH change. Arch Biochem Biophys (1985) 1.13

Chlorinated hydrocarbons in adipose tissue of infants and toddlers: inventory and studies on their association with intake of mothers' milk. Eur J Pediatr (1984) 1.11

Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors. J Biol Chem (1994) 1.10

Apoprotein B structure and receptor recognition of triglyceride-rich low density lipoprotein (LDL) is modified in small LDL but not in triglyceride-rich LDL of normal size. J Biol Chem (1994) 1.07

MRI in tracheal stenosis by innominate artery in children. Pediatr Radiol (1991) 1.04

Effect of codeine on gastrointestinal motility in relation to CYP2D6 phenotype. Clin Pharmacol Ther (1997) 1.02

Four new bioactive polybrominated diphenyl ethers of the sponge Dysidea herbacea from West Sumatra, Indonesia. J Nat Prod (1997) 1.01

Formation and identification of interfacial-active glycolipids from resting microbial cells. Appl Environ Microbiol (1984) 1.01

Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin Pharmacol Ther (1996) 0.99

Involvement of VEGFR-2 (kdr/flk-1) but not VEGFR-1 (flt-1) in VEGF-A and VEGF-C-induced tube formation by human microvascular endothelial cells in fibrin matrices in vitro. Angiogenesis (2001) 0.98

Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry. J Inherit Metab Dis (2005) 0.96

Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer Lett (1999) 0.96

Clusters of perifollicular macrophages in normal murine skin: physiological degeneration of selected hair follicles by programmed organ deletion. J Histochem Cytochem (1998) 0.96

Identification of Actinobacillus actinomycetemcomitans in subgingival plaque by PCR. J Clin Microbiol (1995) 0.92

Functional outcome of closed head injury in children and young adults. Arch Phys Med Rehabil (1984) 0.92

Distribution and changing density of gamma-delta T cells in murine skin during the induced hair cycle. Br J Dermatol (1994) 0.91

Extracranial non-testicular teratoma in childhood and adolescence: introduction of a risk score for stratification of therapy. Klin Padiatr (1997) 0.91

Sequestration, metabolism and partial synthesis of tertiary pyrrolizidine alkaloids by the neotropical leaf-beetle Platyphora boucardi. Insect Biochem Mol Biol (2001) 0.90

Four new bioactive lobane diterpenes of the soft coral Lobophytum pauciflorum from Mindoro, Philippines. J Nat Prod (1998) 0.90

[Recommendations on the structural prerequisites for perinatal care in Germany]. Z Geburtshilfe Neonatol (2006) 0.89

Disposition and first-pass metabolism of ethanol in humans: is it gastric or hepatic and does it depend on gender? Clin Pharmacol Ther (1996) 0.88

New insecticidal rocaglamide derivatives and related compounds from Aglaia oligophylla. J Nat Prod (2001) 0.88

Inhibition of tumor growth and metastasis by targeting tumor-associated angiogenesis with antagonists to the receptors of vascular endothelial growth factor. Invest New Drugs (1999) 0.88

[Reliability of the PRISCUS-PAQ. Questionnaire to assess physical activity of persons aged 70 years and older]. Z Gerontol Geriatr (2010) 0.86

Loss of analgesic effect of morphine due to coadministration of rifampin. Pain (1997) 0.86

Expression of classical and non-classical MHC class I antigens in murine hair follicles. Br J Dermatol (1994) 0.85

Consequences of rifampicin treatment on propafenone disposition in extensive and poor metabolizers of CYP2D6. Pharmacogenetics (1999) 0.85

Pyrrolizidine alkaloids in the arctiid mothHyalurga syma. J Chem Ecol (1993) 0.85

Catalytic activities, protein- and mRNA-expression of cytochrome P450 isoenzymes in intestinal cell lines. Xenobiotica (1998) 0.85

Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method. J Chromatogr B Biomed Sci Appl (1999) 0.84

Assessment of individual CYP2D6 activity in extensive metabolizers with renal failure: comparison of sparteine and dextromethorphan. Clin Pharmacol Ther (1996) 0.84

Acquired antagonistic activity of a bispecific diabody directed against two different epitopes on vascular endothelial growth factor receptor 2. J Immunol Methods (1999) 0.84

Effects of latex avoidance on latex sensitization, atopy and allergic diseases in patients with spina bifida. Allergy (2010) 0.84

Contribution of dihydrocodeine and dihydromorphine to analgesia following dihydrocodeine administration in man: a PK-PD modelling analysis. Br J Clin Pharmacol (2001) 0.84

Rapid, highly sensitive method for the determination of morphine and its metabolites in body fluids by liquid chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl (1999) 0.83

Generation of gene-modified T cells reactive against the angiogenic kinase insert domain-containing receptor (KDR) found on tumor vasculature. Hum Gene Ther (2000) 0.83

MHC class I expression in murine skin: developmentally controlled and strikingly restricted intraepithelial expression during hair follicle morphogenesis and cycling, and response to cytokine treatment in vivo. J Invest Dermatol (1998) 0.83

A new meroditerpenoid dimer from an undescribed Philippine marine sponge of the genus Strongylophora. J Nat Prod (1998) 0.83

Effect of potassium supplementation combined with dietary sodium reduction on blood pressure in men taking antihypertensive medication. J Hypertens Suppl (1988) 0.83

Electrical high frequency stimulation of the caudate nucleus induces local GABA outflow in freely moving rats. J Neurosci Methods (2006) 0.83

Enzyme induction in the elderly: effect of rifampin on the pharmacokinetics and pharmacodynamics of propafenone. Clin Pharmacol Ther (2000) 0.82

Lipid composition of outer stratum corneum and nails in atopic and control subjects. Arch Dermatol Res (1990) 0.82

Monoclonal antibody strategies to block angiogenesis. Drug Discov Today (2001) 0.82

Alkaloid patterns and biosynthetic capacity of root cultures from some pyrrolizidine alkaloid producing Senecio species. Plant Cell Rep (1987) 0.82

Basal concentration of the isoenzyme BB of the glycogen phosphorylase b in human blood. Clin Chim Acta (1993) 0.81

Dihydrocodeine: a new opioid substrate for the polymorphic CYP2D6 in humans. Clin Pharmacol Ther (1995) 0.81

High variation of tioguanine absorption in patients with chronic active Crohn's disease. Aliment Pharmacol Ther (2003) 0.81

Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor. Cancer Res (2001) 0.81

Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans. Eur J Clin Pharmacol (1996) 0.81

Rapid and highly sensitive method for the determination of verapamil, [2H7]verapamil and metabolites in biological fluids by liquid chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl (2000) 0.81

Antigen-gelonin conjugates. Preparation and application in experimental myasthenia gravis. Biol Chem Hoppe Seyler (1987) 0.80

Modification of beta-cell response to different postprandial blood glucose concentrations by prandial repaglinide and combined acarbose/repaglinide application. Diabetes Nutr Metab (2004) 0.80

Sensitive and rapid quantification of busulfan in small plasma volumes by liquid chromatography-electrospray mass spectrometry. Clin Chem (2001) 0.80

Influence of chelation therapy on acute lead intoxication in rats. Arch Toxicol (1975) 0.80

Comparison of S100 protein and MIA protein as serum marker for malignant melanoma. Anticancer Res (2000) 0.80

Quinolizidine alkaloid composition of plants and of photomixotrophic cell suspension cultures of Sarothamnus scoparius and Orobanche rapum-genistae. Planta Med (1981) 0.80

Amino acid sequence determination of the blocked N-terminal tryptic peptide of Neurospora tyrosinase by mass spectrometry. FEBS Lett (1977) 0.80

Bioactive terpenes from the soft coral Heteroxenia sp. from Mindoro, Philippines. Z Naturforsch C (2000) 0.79

An efficient route to the production of an IgG-like bispecific antibody. Protein Eng (2000) 0.79

A simple method to extract essential oils from tissue samples by using microwave radiation. J Chem Ecol (2001) 0.79

In vitro interaction of codeine and diclofenac. Drug Metab Dispos (2000) 0.79

[Measurement of physical activity in older adults. Correlation between the PRISCUS-PAQ and accelerometry]. Z Gerontol Geriatr (2012) 0.79

The effect of the timing and the administration of acarbose on postprandial hyperglycaemia. Diabet Med (1995) 0.78

MR imaging in pediatric airway obstruction. J Comput Assist Tomogr (1990) 0.78

Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake. Eur J Clin Pharmacol (1996) 0.78

Merrekentrones A-D, ipomeamarone-like furanosesquiterpenes from Merremia kentrocaulos. J Nat Prod (2001) 0.78

[Management and therapy of Alzheimer's disease. Recommendations of a general practitioners' guideline]. MMW Fortschr Med (2009) 0.78

Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins. Clin Pharmacol Ther (2009) 0.78