"Affinity-proteomics": direct protein identification from biological material using mass spectrometric epitope mapping.

PubWeight™: 0.81‹?›

🔗 View Article (PMID 12955276)

Published in Anal Bioanal Chem on August 30, 2003

Authors

Marcus Macht1, Andreas Marquardt, Sören-Oliver Deininger, Eugen Damoc, Markus Kohlmann, Michael Przybylski

Author Affiliations

1: Department of Chemistry, Analytical Chemistry, University of Konstanz, 78457 Konstanz, Germany.

Articles by these authors

A dual pressure linear ion trap Orbitrap instrument with very high sequencing speed. Mol Cell Proteomics (2009) 4.75

Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (2003) 4.40

Mass spectrometry-based proteomics using Q Exactive, a high-performance benchtop quadrupole Orbitrap mass spectrometer. Mol Cell Proteomics (2011) 3.75

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol (2006) 3.72

Ultra high resolution linear ion trap Orbitrap mass spectrometer (Orbitrap Elite) facilitates top down LC MS/MS and versatile peptide fragmentation modes. Mol Cell Proteomics (2011) 2.13

ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04

High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies. Nat Methods (2012) 1.67

Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase. Genes Dev (2004) 1.64

MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology. Histochem Cell Biol (2008) 1.53

Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry. J Proteome Res (2010) 1.48

Implications of the serine protease HtrA1 in amyloid precursor protein processing. Proc Natl Acad Sci U S A (2005) 1.47

Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease. Blood (2006) 1.44

Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK. Mol Cell Biol (2004) 1.43

Autoimmunity and inflammation due to a gain-of-function mutation in phospholipase C gamma 2 that specifically increases external Ca2+ entry. Immunity (2005) 1.33

Microfluidic systems in proteomics. Electrophoresis (2003) 1.30

Elucidation of O-glycosylation structures of the beta-amyloid precursor protein by liquid chromatography-mass spectrometry using electron transfer dissociation and collision induced dissociation. J Proteome Res (2009) 1.24

Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family. Eur J Hum Genet (2002) 1.21

Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus. J Immunol (2004) 1.21

Detection and purification of tyrosine-sulfated proteins using a novel anti-sulfotyrosine monoclonal antibody. J Biol Chem (2006) 1.19

Imaging mass spectrometry statistical analysis. J Proteomics (2012) 1.11

From protein complexes to subunit backbone fragments: a multi-stage approach to native mass spectrometry. Anal Chem (2013) 1.08

Revisiting rat spermatogenesis with MALDI imaging at 20-microm resolution. Mol Cell Proteomics (2010) 1.05

Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS. Mol Cell Proteomics (2012) 1.04

Mass spectrometric characterization of glycosylation of hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans. J Am Soc Mass Spectrom (2007) 1.02

Immunoproteomic identification and serological responses to novel Chlamydia pneumoniae antigens that are associated with persistent C. pneumoniae infections. J Immunol (2008) 1.01

Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite. J Biol Chem (2010) 0.99

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2. J Biol Chem (2011) 0.98

N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry. Glycobiology (2006) 0.98

Exploring an orbitrap analyzer for the characterization of intact antibodies by native mass spectrometry. Angew Chem Int Ed Engl (2012) 0.98

Specific nitration at tyrosine 430 revealed by high resolution mass spectrometry as basis for redox regulation of bovine prostacyclin synthase. J Biol Chem (2003) 0.97

Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor. Hypertension (2009) 0.97

Defining the stoichiometry and cargo load of viral and bacterial nanoparticles by Orbitrap mass spectrometry. J Am Chem Soc (2014) 0.93

Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous gland. J Invest Dermatol (2005) 0.92

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis. J Exp Med (2010) 0.91

Mass spectrometric identification of oxidative modifications of tryptophan residues in proteins: chemical artifact or post-translational modification? J Am Soc Mass Spectrom (2010) 0.90

Discrimination of leucine and isoleucine in peptides sequencing with Orbitrap Fusion mass spectrometer. Anal Chem (2014) 0.90

Application of MALDI-TOF-mass spectrometry to proteome analysis using stain-free gel electrophoresis. Top Curr Chem (2013) 0.89

Why the structure but not the activity of the immunoproteasome subunit low molecular mass polypeptide 2 rescues antigen presentation. J Immunol (2012) 0.89

Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. J Biol Chem (2008) 0.88

Interaction of beta-amyloid(1-40) peptide with pairs of metal ions: An electrospray ion trap mass spectrometric model study. Biophys Chem (2009) 0.88

Characterization of the dexniguldipine binding site in the multidrug resistance-related transport protein P-glycoprotein by photoaffinity labeling and mass spectrometry. Mol Pharmacol (2002) 0.87

Approaching MALDI molecular imaging for clinical proteomic research: current state and fields of application. Expert Rev Proteomics (2010) 0.87

Identification of teleost Thy-1 and association with the microdomain/lipid raft reggie proteins in regenerating CNS axons. Mol Cell Neurosci (2003) 0.86

Turning the RING domain protein MdmX into an active ubiquitin-protein ligase. J Biol Chem (2010) 0.86

Determination of primary structure and microheterogeneity of a beta-amyloid plaque-specific antibody using high-performance LC-tandem mass spectrometry. Anal Bioanal Chem (2008) 0.85

Interaction structure of the complex between neuroprotective factor humanin and Alzheimer's β-amyloid peptide revealed by affinity mass spectrometry and molecular modeling. J Pept Sci (2012) 0.85

Functional ubiquitin conjugates with lysine-epsilon-amino-specific linkage by thioether ligation of cysteinyl-ubiquitin peptide building blocks. Bioconjug Chem (2009) 0.85

Mass spectrometric approaches for elucidation of antigenantibody recognition structures in molecular immunology. Eur J Mass Spectrom (Chichester, Eng) (2007) 0.84

Identification, affinity characterisation and biological interactions of lectin-like peptide-carbohydrate complexes derived from human TNF-alpha using high-resolution mass spectrometry. J Pept Sci (2007) 0.84

Determination of ganglioside composition and structure in human brain hemangioma by chip-based nanoelectrospray ionization tandem mass spectrometry. Anal Bioanal Chem (2009) 0.84

Novel β-amino acid derivatives as inhibitors of cathepsin A. J Med Chem (2012) 0.83

Novel Small Molecule Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa) from Natural Product Anabaenopeptin. J Med Chem (2015) 0.82

Discovery and pharmacological characterization of SAR707 as novel and selective small molecule inhibitor of stearoyl-CoA desaturase (SCD1). Eur J Pharmacol (2013) 0.82

Enhanced enzymatic stability and antitumor activity of daunorubicin-GnRH-III bioconjugates modified in position 4. Bioconjug Chem (2011) 0.82

Expression and phosphorylation of the replication regulator protein geminin. Biochem Biophys Res Commun (2003) 0.82

Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometry. Chembiochem (2011) 0.82

Increased levels of antigen-bound β-amyloid autoantibodies in serum and cerebrospinal fluid of Alzheimer's disease patients. PLoS One (2013) 0.82

Utilization of newly developed immobilized enzyme reactors for preparation and study of immunoglobulin G fragments. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.82

Structural characterization of beta-amyloid oligomer-aggregates by ion mobility mass spectrometry and electron spin resonance spectroscopy. Anal Bioanal Chem (2009) 0.81

Thin-chip microspray system for high-performance Fourier-transform ion-cyclotron resonance mass spectrometry of biopolymers. Angew Chem Int Ed Engl (2003) 0.81

Development of an oxime bond containing daunorubicin-gonadotropin-releasing hormone-III conjugate as a potential anticancer drug. Bioconjug Chem (2009) 0.81

Imaging mass spectrometry analysis of renal amyloidosis biopsies reveals protein co-localization with amyloid deposits. Anal Bioanal Chem (2015) 0.81

A synthetic camel anti-lysozyme peptide antibody (peptibody) with flexible loop structure identified by high-resolution affinity mass spectrometry. Chemistry (2006) 0.81

Protein-peptide affinity determination using an h/d exchange dilution strategy: application to antigen-antibody interactions. J Am Soc Mass Spectrom (2010) 0.81

Differentiation of compact and extended conformations of di-ubiquitin conjugates with lysine-specific isopeptide linkages by ion mobility-mass spectrometry. J Am Soc Mass Spectrom (2011) 0.81

Comparison of laser-induced dissociation and high-energy collision-induced dissociation using matrix-assisted laser desorption/ionization tandem time-of-flight (MALDI-TOF/TOF) for peptide and protein identification. Rapid Commun Mass Spectrom (2004) 0.81

Determination of phosphorus-, copper-, and zinc-containing human brain proteins by LA-ICPMS and MALDI-FTICR-MS. Anal Chem (2005) 0.80

De novo sequencing of peptides on single resin beads by MALDI-FTICR tandem mass spectrometry. J Am Soc Mass Spectrom (2009) 0.79

Aberrant processing forms of lung surfactant proteins SP-B and SP-C revealed by high-resolution mass spectrometry. Eur J Mass Spectrom (Chichester, Eng) (2008) 0.79

"Unknown genome" proteomics: a new NADP-dependent epimerase/dehydratase revealed by N-terminal sequencing, inverted PCR, and high resolution mass spectrometry. Mol Cell Proteomics (2008) 0.79

Binding epitopes and interaction structure of the neuroprotective protease inhibitor cystatin C with beta-amyloid revealed by proteolytic excision mass spectrometry and molecular docking simulation. J Med Chem (2009) 0.79

Identification of the epitope for anti-cystatin C antibody. J Mol Recognit (2011) 0.79

Functionalized magnetic micro- and nanoparticles: optimization and application to micro-chip tryptic digestion. Electrophoresis (2006) 0.79

When is mass spectrometry combined with affinity approaches essential? A case study of tyrosine nitration in proteins. J Am Soc Mass Spectrom (2012) 0.79

Structure and functional characterization of the periplasmic N-terminal polypeptide domain of the sugar-specific ion channel protein (ScrY porin). Protein Sci (2002) 0.79

Structure and dynamics of photosystem II light-harvesting complex revealed by high-resolution FTICR mass spectrometric proteome analysis. J Am Soc Mass Spectrom (2008) 0.79

High resolution mass spectrometric alveolar proteomics: identification of surfactant protein SP-A and SP-D modifications in proteinosis and cystic fibrosis patients. Proteomics (2004) 0.79

Imaging mass spectrometry to discriminate breast from pancreatic cancer metastasis in formalin-fixed paraffin-embedded tissues. Proteomics (2014) 0.78

Characterization of oligomerization-aggregation products of neurodegenerative target proteins by ion mobility mass spectrometry. Methods Mol Biol (2012) 0.78

Antigen-bound and free β-amyloid autoantibodies in serum of healthy adults. PLoS One (2012) 0.78

Determination of phosphorus in small amounts of protein samples by ICP-MS. Anal Bioanal Chem (2003) 0.78

High resolution proteome analysis of cryoglobulins using Fourier transform-ion cyclotron resonance mass spectrometry. Proteomics (2003) 0.78

Zinc binding agonist effect on the recognition of the beta-amyloid (4-10) epitope by anti-beta-amyloid antibodies. Biochem Biophys Res Commun (2004) 0.78

Glycosylation profiles of epitope-specific anti-beta-amyloid antibodies revealed by liquid chromatography-mass spectrometry. Glycobiology (2009) 0.78

Identification and structural characterisation of carboxy-terminal polypeptides and antibody epitopes of Alzheimer's amyloid precursor protein using high-resolution mass spectrometry. Eur J Mass Spectrom (Chichester, Eng) (2005) 0.78

Determination of sulfation pattern in brain glycosaminoglycans by chip-based electrospray ionization ion trap mass spectrometry. Anal Bioanal Chem (2009) 0.78

Mass spectrometric identification of the trypsin cleavage pathway in lysyl-proline containing oligotuftsin peptides. J Pept Sci (2007) 0.78

Statistical evaluation of electrospray tandem mass spectra for optimized peptide fragmentation. J Am Soc Mass Spectrom (2005) 0.77

Structure, enzymatic stability and antitumor activity of sea lamprey GnRH-III and its dimer derivatives. Peptides (2007) 0.77

Toward bioinspired galectin mimetics: identification of ligand-contacting peptides by proteolytic-excision mass spectrometry. J Am Chem Soc (2011) 0.77

Lung alveolar proteomics of bronchoalveolar lavage from a pulmonary alveolar proteinosis patient using high-resolution FTICR mass spectrometry. Anal Bioanal Chem (2007) 0.77