Giuseppe Pantaleo

Author PubWeight™ 155.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 2007 5.22
2 Medicine. The need for a global HIV vaccine enterprise. Science 2003 4.70
3 Standardization of cytokine flow cytometry assays. BMC Immunol 2005 4.55
4 Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy. Blood 2003 4.24
5 Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. J Exp Med 2008 4.21
6 HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells. Proc Natl Acad Sci U S A 2005 4.02
7 Impairment of JCV-specific T-cell response by corticotherapy: effect on PML-IRIS management? Neurology 2012 3.63
8 An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses. J Exp Med 2008 3.42
9 Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet 2002 3.32
10 Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence. J Immunol 2005 3.04
11 Dominant TNF-α+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease. Nat Med 2011 2.77
12 Functional signatures of protective antiviral T-cell immunity in human virus infections. Immunol Rev 2006 2.75
13 Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production. J Exp Med 2012 2.46
14 Inadequate T follicular cell help impairs B cell immunity during HIV infection. Nat Med 2013 2.29
15 Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog 2009 2.24
16 Activation of a dendritic cell-T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells. J Exp Med 2008 2.05
17 Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load. Eur J Immunol 2004 2.05
18 Immune responses to JC virus in patients with multiple sclerosis treated with natalizumab: a cross-sectional and longitudinal study. Lancet Neurol 2010 2.02
19 Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities. J Infect Dis 2012 1.89
20 Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proc Natl Acad Sci U S A 2007 1.88
21 Effects of CCR5-Delta32 and CCR2-64I alleles on HIV-1 disease progression: the protection varies with duration of infection. AIDS 2003 1.81
22 Polyfunctional HCV-specific T-cell responses are associated with effective control of HCV replication. Eur J Immunol 2008 1.70
23 IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets. J Allergy Clin Immunol 2009 1.65
24 Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: effects of dosage and route on safety and immunogenicity. Vaccine 2006 1.63
25 EV02: a Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone. Vaccine 2008 1.62
26 Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. Proc Natl Acad Sci U S A 2011 1.55
27 Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells. Proc Natl Acad Sci U S A 2010 1.53
28 IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25. Proc Natl Acad Sci U S A 2010 1.50
29 Analysis of HIV-1- and CMV-specific memory CD4 T-cell responses during primary and chronic infection. Blood 2002 1.45
30 Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C. Vaccine 2006 1.37
31 Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections. Eur J Immunol 2002 1.34
32 Distinct profiles of cytotoxic granules in memory CD8 T cells correlate with function, differentiation stage, and antigen exposure. J Virol 2009 1.27
33 HIV-1 T-cell vaccines: evaluating the next step. Lancet Infect Dis 2007 1.27
34 Treatment of primary HIV-1 infection with cyclosporin A coupled with highly active antiretroviral therapy. J Clin Invest 2002 1.26
35 EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium. Vaccine 2008 1.25
36 Strong EBV-specific CD8+ T-cell response in patients with early multiple sclerosis. Brain 2008 1.24
37 HIV-1 vaccines and adaptive trial designs. Sci Transl Med 2011 1.21
38 Head-to-head comparison on the immunogenicity of two HIV/AIDS vaccine candidates based on the attenuated poxvirus strains MVA and NYVAC co-expressing in a single locus the HIV-1BX08 gp120 and HIV-1(IIIB) Gag-Pol-Nef proteins of clade B. Vaccine 2006 1.18
39 Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One 2011 1.16
40 Functional and phenotypic characterization of tetanus toxoid-specific human CD4+ T cells following re-immunization. Eur J Immunol 2007 1.15
41 Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02). Vaccine 2011 1.15
42 Immune activation alters cellular and humoral responses to yellow fever 17D vaccine. J Clin Invest 2014 1.12
43 Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or atazanavir. J Acquir Immune Defic Syndr 2004 1.12
44 Mycobacterium tuberculosis-specific CD8+ T cells are functionally and phenotypically different between latent infection and active disease. Eur J Immunol 2013 1.12
45 Comparison of human and rhesus macaque T-cell responses elicited by boosting with NYVAC encoding human immunodeficiency virus type 1 clade C immunogens. J Virol 2009 1.11
46 Low levels of human leukocyte antigen donor-specific antibodies detected by solid phase assay before transplantation are frequently clinically irrelevant. Hum Immunol 2009 1.09
47 De novo T-cell generation in patients at different ages and stages of HIV-1 disease. Blood 2004 1.07
48 Cytomegalovirus (CMV)-specific cellular immune responses. Hum Immunol 2004 1.06
49 Improved NYVAC-based vaccine vectors. PLoS One 2011 1.04
50 Expansion and tissue infiltration of an allospecific CD4+CD25+CD45RO+IL-7Ralphahigh cell population in solid organ transplant recipients. J Exp Med 2007 1.04
51 Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressors. PLoS One 2011 1.02
52 Functional avidity: a measure to predict the efficacy of effector T cells? Clin Dev Immunol 2012 1.01
53 Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expression. J Virol 2010 0.98
54 DNA/NYVAC vaccine regimen induces HIV-specific CD4 and CD8 T-cell responses in intestinal mucosa. J Virol 2011 0.97
55 Immune response to HIV. Curr Opin HIV AIDS 2013 0.97
56 Deletion of the viral anti-apoptotic gene F1L in the HIV/AIDS vaccine candidate MVA-C enhances immune responses against HIV-1 antigens. PLoS One 2012 0.96
57 Differences in HCV-specific T cell responses between chronic HCV infection and HIV/HCV co-infection. Eur J Immunol 2005 0.96
58 The functional and structural neural basis of individual differences in loss aversion. J Neurosci 2013 0.94
59 Intrathecal immune responses to EBV in early MS. Eur J Immunol 2010 0.94
60 NYVAC immunization induces polyfunctional HIV-specific T-cell responses in chronically-infected, ART-treated HIV patients. Eur J Immunol 2012 0.94
61 The number of Toll-like receptor 9-agonist motifs in the adenovirus genome correlates with induction of dendritic cell maturation by adenovirus immune complexes. J Virol 2012 0.94
62 Transepithelial transport of HIV-1 by M cells is receptor-mediated. Proc Natl Acad Sci U S A 2002 0.94
63 Functional patterns of HIV-1-specific CD4 T-cell responses in children are influenced by the extent of virus suppression and exposure. AIDS 2007 0.94
64 Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C. PLoS One 2013 0.92
65 The polymorphic nature of HIV type 1 env V4 affects the patterns of potential N-glycosylation sites in proviral DNA at the intrahost level. AIDS Res Hum Retroviruses 2009 0.92
66 Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys. J Immunol 2010 0.92
67 The immune space: a concept and template for rationalizing vaccine development. AIDS Res Hum Retroviruses 2014 0.92
68 Independent evolution of hypervariable regions of HIV-1 gp120: V4 as a swarm of N-Linked glycosylation variants. AIDS Res Hum Retroviruses 2008 0.92
69 Attenuated poxviruses expressing a synthetic HIV protein stimulate HLA-A2-restricted cytotoxic T-cell responses. Vaccine 2004 0.92
70 CSF enrichment of highly differentiated CD8+ T cells in early multiple sclerosis. Clin Immunol 2006 0.91
71 HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial. J Clin Invest 2014 0.88
72 Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C. PLoS One 2012 0.87
73 Rapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells. PLoS Pathog 2013 0.87
74 HIV-1 drug resistance transmission networks in southwest Switzerland. AIDS Res Hum Retroviruses 2010 0.87
75 Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism. Virology 2010 0.86
76 Effects of immunosuppressive drugs on HIV infection: implications for solid-organ transplantation. Transpl Int 2007 0.86
77 Indicators of therapeutic effect in FIT-06, a Phase II trial of a DNA vaccine, GTU(®)-Multi-HIVB, in untreated HIV-1 infected subjects. Vaccine 2012 0.85
78 Prevalence of anti-HLA antibodies after liver transplantation. Transpl Int 2009 0.84
79 Large TCR diversity of virus-specific CD8 T cells provides the mechanistic basis for massive TCR renewal after antigen exposure. J Immunol 2011 0.84
80 A soluble hexameric form of CD40 ligand activates human dendritic cells and augments memory T cell response. Vaccine 2008 0.84
81 Multicenter evaluation of the Elecsys® anti-HCV II assay for the diagnosis of hepatitis C virus infection. J Med Virol 2013 0.83
82 Intraoral epimucosal fixation for reducible maxillary fractures of the jaws; surgical considerations in comparison to current techniques. J Craniofac Surg 2014 0.83
83 Clinical studies of experimental vaccines. Curr Opin HIV AIDS 2006 0.83
84 Vitamin D has a direct immunomodulatory effect on CD8+ T cells of patients with early multiple sclerosis and healthy control subjects. J Neuroimmunol 2010 0.82
85 Severe post-EBV encephalopathy associated with myelin oligodendrocyte glycoprotein-specific immune response. J Neuroimmunol 2007 0.81
86 Natural killer cell receptor--repertoire and functions after induction therapy by polyclonal rabbit anti-thymocyte globulin in unsensitized kidney transplant recipients. Clin Immunol 2010 0.81
87 Chin Wing Osteotomy for Bilateral Goldenhar Syndrome Treated by "Chin Wing Mentoplasty": Aesthetic, Functional, and Histological Considerations. J Craniofac Surg 2015 0.81
88 Ridge Expansion by Flapless Split Crest and Immediate Implant Placement: Evolution of the Technique. J Craniofac Surg 2016 0.81
89 Modulation of human memory T-cell function by different antigen-presenting cells. Eur J Immunol 2011 0.81
90 Long-term persistence of HIV-1 vaccine-induced CD4+CD45RA-CD62L-CCR7- memory T-helper cells. AIDS 2004 0.80
91 Biosimilar epoetin in elderly patients with low-risk myelodysplastic syndromes improves anemia, quality of life, and brain function. Ann Hematol 2014 0.80
92 HLA-B7-restricted EBV-specific CD8+ T cells are dysregulated in multiple sclerosis. J Immunol 2012 0.80
93 A Patient With a Rare Single Mandibular Localization of Non-Hodgkin B-Cell Lymphoma: Early Differential Diagnosis With Dental Lesions. J Craniofac Surg 2015 0.80
94 A novel HIV vaccine adjuvanted by IC31 induces robust and persistent humoral and cellular immunity. PLoS One 2012 0.80
95 Three-year immune reconstitution in PI-sparing and PI-containing antiretroviral regimens in advanced HIV-1 disease. Antivir Ther 2007 0.80
96 Monitoring of CD4+CD25highIL-7Rαhigh activated T cells in kidney transplant recipients. Clin J Am Soc Nephrol 2011 0.80
97 HIV-1 superinfection with a triple-class drug-resistant strain in a patient successfully controlled with antiretroviral treatment. AIDS 2014 0.79
98 Carriers of the fragile X mental retardation 1 (FMR1) premutation allele present with increased levels of cytokine IL-10. J Neuroinflammation 2012 0.79
99 Recurrent brain tumour: the impact of illness on patient's life. Support Care Cancer 2011 0.79
100 Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication? AIDS 2005 0.79
101 Hepatitis C virus infection after liver transplantation is associated with lower levels of activated CD4(+)CD25(+)CD45RO(+)IL-7ralpha(high) T cells. Liver Transpl 2010 0.79
102 c-Cbl expression levels regulate the functional responses of human central and effector memory CD4 T cells. Blood 2008 0.79
103 Relationship between structure and CO oxidation activity of ceria-supported gold catalysts. J Phys Chem B 2005 0.79
104 HIV-1-specific immune response. Adv Pharmacol 2008 0.78
105 Role of HIV-1-specific CD4 T cells. Curr Opin HIV AIDS 2006 0.78
106 New Technique for Mandibular Symphyseal Distraction by a Double-Level Anchorage and Fixation System: Advantages and Results. J Craniofac Surg 2016 0.77
107 Systems biology in the development of HIV vaccines. Curr Opin HIV AIDS 2012 0.77
108 The impact of an aging population on the diagnosis of pulmonary embolism: comparison of young and elderly patients. Clin Appl Thromb Hemost 2007 0.77
109 Immune-based interventions in HIV infection: doing the right studies, getting the right answers. AIDS 2006 0.77
110 Osteodistraction With Dental Implant-Borne Devices for Bone Regeneration in Atrophied Premaxilla. J Craniofac Surg 2016 0.77
111 MOBP-specific cellular immune responses are weaker than MOG-specific cellular immune responses in patients with multiple sclerosis and healthy subjects. Neurol Sci 2012 0.77
112 Lifelong dynamics of human CD4+CD25+ regulatory T cells: insights from in vivo data and mathematical modeling. J Theor Biol 2010 0.76
113 Salvage therapy with bortezomib and dexamethasone in elderly patients with relapsed/refractory multiple myeloma. Anticancer Drugs 2015 0.76
114 Understanding what makes a good versus a bad vaccine. Eur J Immunol 2005 0.75
115 Implant prosthetic rehabilitation with bone regenerative techniques after fracture of the upper central incisors. Case Rep Dent 2013 0.75
116 Effort processes in achieving performance outcomes: interrelations among and roles of core constructs. Behav Brain Sci 2013 0.75
117 Unsung hero Robert C. Gallo. Science 2009 0.75
118 Are all donor-specific antibodies detected by solid-phase assay before transplantation clinically relevant? Transplantation 2009 0.75
119 B-cell abnormalities and impact on antibody response in HIV infection. Curr Opin HIV AIDS 2017 0.75
120 Metal-support interaction and redox behavior of Pt(1 wt %)/Ce0.6Zr0.4O2. J Phys Chem B 2006 0.75
121 Antiviral memory T cell responses: correlation with protective immunity and implication for vaccine development. Adv Exp Med Biol 2002 0.75
122 One year on: vale Joep Lange. Curr Opin HIV AIDS 2015 0.75
123 Combined sulfating and non-sulfating support to prevent water and sulfur poisoning of Pd catalysts for methane combustion. Chem Commun (Camb) 2010 0.75
124 Chemical-physical properties of spinel CoMn2O4 nano-powders and catalytic activity in the 2-propanol and toluene combustion: Effect of the preparation method. J Environ Sci Health A Tox Hazard Subst Environ Eng 2011 0.75
125 Thirty years of HIV: what have we learned? Curr Opin HIV AIDS 2013 0.75
126 [Immunological signatures: a new tool to diagnose active tuberculosis disease?]. Med Sci (Paris) 2011 0.75
127 B-cell abnormalities and impact on antibody response in HIV infection. Curr Opin HIV AIDS 2017 0.75
128 Osteodistraction With Dental Implant-Borne Devices for Bone Regeneration in Atrophied Premaxilla. J Craniofac Surg 2016 0.75
129 A new cell for the study of in situ chemical reactions using X-ray absorption spectroscopy. J Synchrotron Radiat 2005 0.75
130 Reply to Kadayifci and Yildirim. Endoscopy 2016 0.75
131 Four-year post-loading results of full-arch rehabilitation with immediate placement and immediate loading implants: A retrospective controlled study. Quintessence Int 2017 0.75
132 Cytokine mRNA profile of Epstein-Barr virus-stimulated highly differentiated T cells in multiple sclerosis: a pilot study. J Neuroimmunol 2010 0.75
133 Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1. AIDS Res Hum Retroviruses 2011 0.75