Published in Proc Natl Acad Sci U S A on September 15, 2003
Rapid oxime and hydrazone ligations with aromatic aldehydes for biomolecular labeling. Bioconjug Chem (2008) 2.25
Creating advanced multifunctional biosensors with surface enzymatic transformations. Langmuir (2006) 1.35
Using polymeric materials to generate an amplified response to molecular recognition events. Nat Mater (2007) 1.33
Simultaneous detection of microsatellite repeats and SNPs in the macrophage migration inhibitory factor (MIF) gene by thin-film biosensor chips and application to rural field studies. Nucleic Acids Res (2005) 1.24
Single-nucleotide polymorphism genotyping by nanoparticle-enhanced surface plasmon resonance imaging measurements of surface ligation reactions. Anal Chem (2006) 1.20
The Vector Population Monitoring Tool (VPMT): High-Throughput DNA-Based Diagnostics for the Monitoring of Mosquito Vector Populations. Malar Res Treat (2010) 1.06
MIF, MIF alleles, and prospects for therapeutic intervention in autoimmunity. J Clin Immunol (2012) 1.04
Rapid detection of rpoB gene mutations conferring rifampin resistance in Mycobacterium tuberculosis. J Clin Microbiol (2012) 1.02
Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene. BMC Genet (2006) 0.89
ALFRED: an allele frequency database for microevolutionary studies. Evol Bioinform Online (2007) 0.89
A fluorescence light-up Ag nanocluster probe that discriminates single-nucleotide variants by emission color. J Am Chem Soc (2012) 0.88
Genotyping of single nucleotide substitutions. Clin Biochem Rev (2006) 0.85
Visible Genotype Sensor Array. Sensors (Basel) (2008) 0.75
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature (2001) 42.18
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet (1999) 17.09
Comprehensive human genome amplification using multiple displacement amplification. Proc Natl Acad Sci U S A (2002) 13.58
Pyrosequencing sheds light on DNA sequencing. Genome Res (2001) 11.87
Mutation detection and single-molecule counting using isothermal rolling-circle amplification. Nat Genet (1998) 9.84
Allelic discrimination using fluorogenic probes and the 5' nuclease assay. Genet Anal (1999) 9.80
Methods for genotyping single nucleotide polymorphisms. Annu Rev Genomics Hum Genet (2001) 5.79
Accessing genetic variation: genotyping single nucleotide polymorphisms. Nat Rev Genet (2001) 5.00
Linkage disequilibrium: what history has to tell us. Trends Genet (2002) 4.33
Whole genome analysis of genetic alterations in small DNA samples using hyperbranched strand displacement amplification and array-CGH. Genome Res (2003) 4.10
Polymorphism of DNA sequence in the beta-globin gene region. Application to prenatal diagnosis of beta 0 thalassemia in Sardinia. N Engl J Med (1980) 3.72
Interrelation of hyperhomocyst(e)inemia, factor V Leiden, and risk of future venous thromboembolism. Circulation (1997) 3.23
High level multiplex genotyping by MALDI-TOF mass spectrometry. Nat Biotechnol (1998) 3.22
A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays. Genome Res (2000) 2.94
Improving the fidelity of Thermus thermophilus DNA ligase. Nucleic Acids Res (1996) 2.58
Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction. Proc Natl Acad Sci U S A (2000) 2.21
Risk factors for venous thrombosis: prevalence, risk, and interaction. Semin Hematol (1997) 1.68
Enhanced discrimination of single nucleotide polymorphisms by artificial mismatch hybridization. Nat Biotechnol (1997) 1.53
Genotyping SNPs with molecular beacons. Methods Mol Biol (2003) 1.50
Single nucleotide polymorphism seeking long term association with complex disease. Nucleic Acids Res (2002) 1.33
Visualization of oligonucleotide probes and point mutations in interphase nuclei and DNA fibers using rolling circle DNA amplification. Proc Natl Acad Sci U S A (2001) 1.26
Interference-based detection of nucleic acid targets on optically coated silicon. Nat Biotechnol (2001) 1.17
Genotyping single-nucleotide polymorphisms by the invader assay with dual-color fluorescence polarization detection. Clin Chem (2001) 1.07
Integration of DNA ligation and rolling circle amplification for the homogeneous, end-point detection of single nucleotide polymorphisms. Nucleic Acids Res (2002) 1.02
Silicon-based biosensors for rapid detection of protein or nucleic acid targets. Clin Chem (2001) 0.91
Visual detection of organic monomolecular films by interference colors. Appl Opt (1985) 0.85
Genetic structure of human populations. Science (2002) 30.91
A human genome diversity cell line panel. Science (2002) 14.11
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet (2012) 7.00
Diagnostic markers for early detection of ovarian cancer. Clin Cancer Res (2008) 6.47
A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res (2008) 5.05
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Implications of biogeography of human populations for 'race' and medicine. Nat Genet (2004) 3.34
Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens. Cancer Prev Res (Phila) (2011) 3.33
The genetic structure of Pacific Islanders. PLoS Genet (2008) 3.31
Serum protein markers for early detection of ovarian cancer. Proc Natl Acad Sci U S A (2005) 3.22
A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer. Cancer Prev Res (Phila) (2011) 3.03
Intelligence, race, and genetics. Am Psychol (2005) 2.76
ALFRED: An allele frequency database for anthropology. Am J Phys Anthropol (2002) 2.67
A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am J Hum Genet (2002) 2.60
Developing a SNP panel for forensic identification of individuals. Forensic Sci Int (2005) 2.55
Evidence of positive selection acting at the human dopamine receptor D4 gene locus. Proc Natl Acad Sci U S A (2001) 2.48
Global diversity and evidence for coevolution of KIR and HLA. Nat Genet (2007) 2.40
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet (2009) 2.35
Bitter receptor gene (TAS2R38), 6-n-propylthiouracil (PROP) bitterness and alcohol intake. Alcohol Clin Exp Res (2004) 2.26
Supertasting and PROP bitterness depends on more than the TAS2R38 gene. Chem Senses (2008) 2.18
Low nucleotide diversity in chimpanzees and bonobos. Genetics (2003) 2.16
Vibratory Urticaria Associated with a Missense Variant in ADGRE2. N Engl J Med (2016) 2.09
Inferring the demographic history of African farmers and pygmy hunter-gatherers using a multilocus resequencing data set. PLoS Genet (2009) 2.07
Phenotypic correction of murine hemophilia A using an iPS cell-based therapy. Proc Natl Acad Sci U S A (2009) 2.02
Effects of traditional and western environments on prevalence of type 2 diabetes in Pima Indians in Mexico and the U.S. Diabetes Care (2006) 1.96
Maternal traces of deep common ancestry and asymmetric gene flow between Pygmy hunter-gatherers and Bantu-speaking farmers. Proc Natl Acad Sci U S A (2008) 1.96
Survival in cerebral palsy in the last 20 years: signs of improvement? Dev Med Child Neurol (2007) 1.88
Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells. Proc Natl Acad Sci U S A (2007) 1.80
Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. Proc Natl Acad Sci U S A (2008) 1.75
Linkage disequilibrium patterns vary substantially among populations. Eur J Hum Genet (2005) 1.73
Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells. Proc Natl Acad Sci U S A (2010) 1.67
Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk. Cell Cycle (2011) 1.64
Cigarette smoking and erectile dysfunction among Chinese men without clinical vascular disease. Am J Epidemiol (2007) 1.62
Structural diversity and African origin of the 17q21.31 inversion polymorphism. Nat Genet (2012) 1.62
Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus. Am J Hum Genet (2002) 1.61
SALL4 is a key regulator of survival and apoptosis in human leukemic cells. Blood (2008) 1.61
Mycobacterium tuberculosis cells growing in macrophages are filamentous and deficient in FtsZ rings. J Bacteriol (2006) 1.59
Refined geographic distribution of the oriental ALDH2*504Lys (nee 487Lys) variant. Ann Hum Genet (2009) 1.49
Genotyping and haplotyping of CYP2C19 functional alleles on thin-film biosensor chips. Pharmacogenet Genomics (2007) 1.49
The evolution and population genetics of the ALDH2 locus: random genetic drift, selection, and low levels of recombination. Ann Hum Genet (2004) 1.49
Evidence of positive selection on a class I ADH locus. Am J Hum Genet (2007) 1.48
Efficacy and the strength of evidence of U.S. alcohol control policies. Am J Prev Med (2013) 1.47
SNPs for a universal individual identification panel. Hum Genet (2010) 1.42
High-throughput ribozyme-based assays for detection of viral nucleic acids. Chem Biol (2004) 1.42
Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts. Cell Biol Int (2009) 1.39
Candidate SNPs for a universal individual identification panel. Hum Genet (2007) 1.39
Geographically separate increases in the frequency of the derived ADH1B*47His allele in eastern and western Asia. Am J Hum Genet (2007) 1.37
Using polymeric materials to generate an amplified response to molecular recognition events. Nat Mater (2007) 1.33
Directly observed therapy for the management of HIV-infected patients in a methadone program. Clin Infect Dis (2004) 1.33
On the use of DNA pooling to estimate haplotype frequencies. Genet Epidemiol (2003) 1.33
Vegetable Intake in College-Aged Adults Is Explained by Oral Sensory Phenotypes and TAS2R38 Genotype. Chemosens Percept (2010) 1.32
The distribution and most recent common ancestor of the 17q21 inversion in humans. Am J Hum Genet (2010) 1.31
Haplotype block structures show significant variation among populations. Genet Epidemiol (2004) 1.28
Genetic differences in human circadian clock genes among worldwide populations. J Biol Rhythms (2008) 1.27
Significant variation in haplotype block structure but conservation in tagSNP patterns among global populations. Eur J Hum Genet (2007) 1.26
Circulating tumor cells as a predictive biomarker in patients with hormone-sensitive prostate cancer. Clin Genitourin Cancer (2011) 1.25
Simultaneous detection of microsatellite repeats and SNPs in the macrophage migration inhibitory factor (MIF) gene by thin-film biosensor chips and application to rural field studies. Nucleic Acids Res (2005) 1.24
Analyses of a set of 128 ancestry informative single-nucleotide polymorphisms in a global set of 119 population samples. Investig Genet (2011) 1.22
Obsessive-compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndrome. Am J Med Genet B Neuropsychiatr Genet (2003) 1.21
Intra- and interpopulation genotype reconstruction from tagging SNPs. Genome Res (2006) 1.21
Determining the model for end-stage liver disease with better accuracy: neutralizing the international normalized ratio pitfalls. Hepatology (2007) 1.19
Signatures of purifying and local positive selection in human miRNAs. Am J Hum Genet (2009) 1.18
Isolation, characterization, and in vitro propagation of infantile hemangioma stem cells and an in vivo mouse model. J Hematol Oncol (2011) 1.18
SRI-286, a thiosemicarbazole, in combination with mefloquine and moxifloxacin for treatment of murine Mycobacterium avium complex disease. Antimicrob Agents Chemother (2004) 1.17
Comparison of circulating MicroRNA 141 to circulating tumor cells, lactate dehydrogenase, and prostate-specific antigen for determining treatment response in patients with metastatic prostate cancer. Clin Genitourin Cancer (2011) 1.16
Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors. Cancer Epidemiol Biomarkers Prev (2009) 1.14
Use of autosomal loci for clustering individuals and populations of East Asian origin. Hum Genet (2005) 1.13
Possible epistatic role of ADH7 in the protection against alcoholism. Am J Med Genet B Neuropsychiatr Genet (2004) 1.13
Genomewide scan of hoarding in sib pairs in which both sibs have Gilles de la Tourette syndrome. Am J Hum Genet (2002) 1.13
International collaborative study of cardiovascular disease in Asia: design, rationale, and preliminary results. Ethn Dis (2004) 1.12
ALFRED: an allele frequency resource for research and teaching. Nucleic Acids Res (2011) 1.12