Published in J Pharmacol Exp Ther on June 01, 1953
A modification of receptor theory. Br J Pharmacol Chemother (1956) 14.20
The role of calcium in the secretory response of the adrenal medulla to acetylcholine. J Physiol (1961) 8.70
Receptors for 5-hydroxytryptamine and noradrenaline in rabbit isolated ear artery and aorta. Br J Pharmacol (1976) 3.95
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. J Clin Invest (2005) 3.08
Comparison of the actions of U-46619, a prostaglandin H2-analogue, with those of prostaglandin H2 and thromboxane A2 on some isolated smooth muscle preparations. Br J Pharmacol (1981) 2.79
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood (2005) 2.76
GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro. Br J Pharmacol (1989) 2.39
Nitrite as regulator of hypoxic signaling in mammalian physiology. Med Res Rev (2009) 2.15
Endothelium-dependent relaxation of the pig aorta: relationship to stimulation of 86Rb efflux from isolated endothelial cells. Br J Pharmacol (1983) 1.94
Evidence for two types of excitatory receptor for 5-hydroxytryptamine in dog isolated vasculature. Br J Pharmacol (1980) 1.86
Supersensitivity of atherosclerotic rabbit aorta to ergonovine. Mediation by a serotonergic mechanism. J Clin Invest (1980) 1.84
Artery wall electrolytes in renal and DCA hypertension. J Clin Invest (1954) 1.80
Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics. Cardiovasc Res (2007) 1.69
The pharmacological properties of fibrinogen degradation products. Br J Pharmacol (1969) 1.67
The functional nitrite reductase activity of the heme-globins. Blood (2008) 1.58
Studies on the induction of pharmacological responses to des-Arg9-bradykinin in vitro and in vivo. Br J Pharmacol (1987) 1.56
THE BETA-ADRENERGIC BLOCKING AND PRESSOR ACTION OF ISOPRENALINE IN THE CAT. Br J Pharmacol Chemother (1963) 1.51
Nitrite regulates hypoxic vasodilation via myoglobin-dependent nitric oxide generation. Circulation (2012) 1.40
The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal. Arch Biochem Biophys (2008) 1.36
Antagonism of the response of human isolated arteries to noradrenaline. Br J Pharmacol (1969) 1.35
Nitrite confers protection against myocardial infarction: role of xanthine oxidoreductase, NADPH oxidase and K(ATP) channels. J Mol Cell Cardiol (2007) 1.30
Quantitative analysis on isolated organs of the autonomic blocking properties of indoramin hydrochloride (Wy 21901). Br J Pharmacol (1972) 1.29
U-46619, a selective thromboxane A2-like agonist? [proceedings]. Br J Pharmacol (1980) 1.28
Dietary nitrite restores NO homeostasis and is cardioprotective in endothelial nitric oxide synthase-deficient mice. Free Radic Biol Med (2008) 1.27
Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway. Br J Clin Pharmacol (2013) 1.26
Mechanisms of nitrite bioactivation. Nitric Oxide (2013) 1.22
Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta. Br J Pharmacol (1971) 1.21
The effect of norepinephrine on the electrolyte composition of arterial smooth muscle. J Clin Invest (1956) 1.19
Safety and feasibility of long-term intravenous sodium nitrite infusion in healthy volunteers. PLoS One (2011) 1.19
Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat. Am J Physiol Heart Circ Physiol (2008) 1.17
Effects of isoprenaline and phenylephrine on energy-rich phosphate compounds and glucose-6-phosphate in smooth and cardiac muscle. Br J Pharmacol (1971) 1.13
The removal of noradrenaline in the pulmonary circulation of rat isolated lungs. Br J Pharmacol (1973) 1.12
Low-dose sodium nitrite vasodilates hypoxic human pulmonary vasculature by a means that is not dependent on a simultaneous elevation in plasma nitrite. Am J Physiol Heart Circ Physiol (2009) 1.11
CONTRACTION OF VASCULAR SMOOTH MUSCLE. Can Med Assoc J (1964) 1.08
The cellular site of action of angiotensin. J Cell Biol (1971) 1.08
Nitrite directly vasodilates hypoxic vasculature via nitric oxide-dependent and -independent pathways. Br J Pharmacol (2009) 1.07
Nitrite in pulmonary arterial hypertension: therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling. Cardiovasc Res (2010) 1.05
Proceedings: Chemical sympathectomy of the rabbit with 6-hydroxydopamine. Br J Pharmacol (1973) 1.04
Adverse effects of tris hydrochloride, a commonly used buffer in physiological media. J Physiol (1976) 1.01
The potential role of the red blood cell in nitrite-dependent regulation of blood flow. Cardiovasc Res (2010) 1.00
Studies on the longitudinal muscle of the anterior mesentric artery of the domestic fowl. J Physiol (1968) 0.99
Effect of propranolol on alpha-adrenergic blockade in the dog and isolated rabbit aortic strip. Br J Pharmacol Chemother (1967) 0.98
Profile of circulating vasoactive substances in hemorrhagic shock and their pharmacologic manipulation. J Clin Invest (1974) 0.98
Nitrite and nitric oxide metabolism in peripheral artery disease. Nitric Oxide (2012) 0.97
The alpha- and beta-adrenoceptor blocking potencies of labetalol and its individual stereoisomers in anaesthetized dogs and in isolated tissues. Br J Pharmacol (1982) 0.96
Inhibition by quinine of endothelium-dependent relaxation of rabbit aortic strips. Br J Pharmacol (1987) 0.94
Proceedings: Receptors for 5-hydroxytryptamine and noradrenaline in rabbit aorta and central ear artery. Br J Pharmacol (1974) 0.93
Aetiology of cerebral arterial spasm following subarachnoid haemorrhage: evidence against a major involvement of 5-hydroxy-tryptamine in the production of acute spasm. Br J Clin Pharmacol (1978) 0.93
Nitrates and nitrites in the treatment of ischemic cardiac disease. Cardiol Rev (2010) 0.92
Receptor mechanisms for 5-hydroxytryptamine in rabbit arteries. Br J Pharmacol (1981) 0.90
Effects of peptidase inhibition on angiotensin receptor agonist and antagonist potency in rabbit isolated thoracic aorta. Br J Pharmacol (1992) 0.90
Pharmacokinetic and pharmacodynamic studies with two alpha-adrenoceptor antagonists, doxazosin and prazosin in the rabbit. Br J Pharmacol (1985) 0.89
Mitochondrial aldehyde dehydrogenase mediates vasodilator responses of glyceryl trinitrate and sodium nitrite in the pulmonary vascular bed of the rat. Am J Physiol Heart Circ Physiol (2010) 0.89
AN INVESTIGATION OF THE ADRENERGIC BLOCKING ACTION OF CHLORPROMAZINE. Br J Pharmacol Chemother (1964) 0.89
Non-competitive antagonism of the alpha-adrenoceptor-mediated fast component of contraction of rat aorta, by doxazosin and prazosin. Br J Pharmacol (1983) 0.88
A new bioassay for glucagon. Br J Pharmacol (1978) 0.86
Calcium leakage as a cause of the high resting tension in vascular smooth muscle from the spontaneously hypertensive rat. Proc Natl Acad Sci U S A (1978) 0.86
Effect of chronic sodium nitrite therapy on monocrotaline-induced pulmonary hypertension. Nitric Oxide (2012) 0.85
Hepoxilins sensitize blood vessels to noradrenaline--stereospecificity of action. Br J Pharmacol (1992) 0.85
The response of the circular muscle layer of the guinea-pig isolated vas deferens to transmural electrical stimulation. Br J Pharmacol (1978) 0.85
Models for investigating the aetiology of cerebral arterial spasm: comparative responses of the human basilar artery with rat colon, anococcygeus, stomach fundus, and aorta and guinea-pig ileum and colon. Br J Pharmacol (1978) 0.84
Characterization of angiotensin receptors in vascular and intestinal smooth muscles. Br J Pharmacol (1973) 0.84
The Nitrate-Nitrite-NO Pathway and Its Implications for Heart Failure and Preserved Ejection Fraction. Curr Heart Fail Rep (2016) 0.84
Preliminary pharmacological characterization of the bovine isolated bronchial artery strip: a new preparation. Br J Pharmacol (1980) 0.83
The Impact of Hyperthermia on Receptor-Mediated Interleukin-6 Regulation in Mouse Skeletal Muscle. PLoS One (2016) 0.83
Anaphylactic contraction of pulmonary blood vessels of chicken. Br J Pharmacol (1977) 0.82
Actions of quazodine (MJ1988) on smooth muscle. Br J Pharmacol (1971) 0.82
The effect of oxytocin on contractile responses and 45Ca movements in rat isolated aortic strips. Br J Pharmacol (1986) 0.82
Crosstalk between nitrite, myoglobin and reactive oxygen species to regulate vasodilation under hypoxia. PLoS One (2014) 0.81
Demonstration of different contractile mechanisms for angiotensin II and des-Asp1-angiotensin II in rabbit aortic strips. Proc Natl Acad Sci U S A (1977) 0.81
Analysis of responses to glyceryl trinitrate and sodium nitrite in the intact chest rat. Nitric Oxide (2012) 0.81
Aortic vascular and atrial responses to (+/-)-1-O-octadecyl-2-acetyl-glyceryl-3-phosphorylcholine. Br J Pharmacol (1983) 0.81
Potentiation of inhibitory and excitatory effects of catechol amines by bretylium. Br J Pharmacol Chemother (1961) 0.81
The action of tyramine on the dog isolated atrium. Br J Pharmacol Chemother (1963) 0.81
Nitrate ingestion: a review of the health and physical performance effects. Nutrients (2014) 0.80
Nicotine and the effect of antisympathomimetic agents on the aorta of the rabbit. Br J Pharmacol Chemother (1959) 0.80
It is rocket science - why dietary nitrate is hard to 'beet'! Part I: twists and turns in the realization of the nitrate-nitrite-NO pathway. Br J Clin Pharmacol (2016) 0.80
Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig. Br J Pharmacol (1968) 0.80
Pharmacology of LR-B/081, a new highly potent, selective and orally active, nonpeptide angiotensin II AT1 receptor antagonist. Br J Pharmacol (1995) 0.79
Effects of Bay K 8644 and nifedipine on femoral arteries of spontaneously hypertensive rats. Br J Pharmacol (1986) 0.79
A modification of receptor theory. 1956. Br J Pharmacol (1997) 0.79
The cellular mechanism of action of nimodipine (BAY e 9736), a new calcium antagonist [proceedings]. Br J Pharmacol (1979) 0.78
Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR. Sci Rep (2016) 0.77
Pressor substances in arterial hypertension. V. Chemical and pharmacological characteristics of pherentasin. J Exp Med (1955) 0.77
The evolution of nitric oxide signalling in vertebrate blood vessels. J Comp Physiol B (2014) 0.77
Potentiation of the contractile response to acetylcholine in aortic strips by low concentrations of vascular contractile agonists. Br J Pharmacol (1980) 0.77
Nitrite, NO and hypoxic vasodilation. Br J Pharmacol (2009) 0.76
Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans. Br J Pharmacol (2015) 0.76
[Hypertension and increased excretion of catecholamines]. Arch Kreislaufforsch (1966) 0.76
Coronary anaphylaxis in vitro. Br J Pharmacol (1979) 0.75
ANGIOTENSIN AND BRADYKININ: A STUDY IN CONTRASTS. Can Med Assoc J (1964) 0.75
Effects of infectious bovine rhinotracheitis virus infection on bovine airway reactivity. Can J Vet Res (1987) 0.75
From depolarization-dependent contractions in gastrointestinal smooth muscle to aortic pulse-synchronized contractions. Clin Exp Gastroenterol (2014) 0.75
Fruits serotonin and catechol amines. Can Med Assoc J (1959) 0.75
The evaluation of the novel pressor activity of gamma-piperidinobutyramide (WY 20051, DF480). Br J Pharmacol (1976) 0.75
Identification of the smooth muscle excitatory receptors for ergot alkaloids. Br J Pharmacol Chemother (1962) 0.75
ANNOTATIONS. Br Med J (1961) 0.75
Beta-adrenoceptor stimulating properties of para-dimethylaminobenzaldehyde. Br J Pharmacol (1970) 0.75
Anaphylactic contraction (Schultz-Dale reaction) of the bovine bronchial artery in vitro. Br J Pharmacol (1983) 0.75
Individual variations of prostanoid agonist responses in rabbit aorta: evidence for the independent regulation of prostanoid receptor subtypes. Br J Pharmacol (1987) 0.75
The pharmacology of vascular smooth muscle. Pharmacol Rev (1955) 6.60
Dibenamine blockade in strips of rabbit aorta and its use in differentiating receptors. J Pharmacol Exp Ther (1954) 4.36
The receptors for epinephrine and norepinephrine (adrenergic receptors). Pharmacol Rev (1959) 2.98
Spiral-cut strip of rabbit aorta for in vitro studies of responses of arterial smooth muscle. Methods Med Res (1960) 2.57
ACTIONS AND INTERACTIONS OF NOREPINEPHRINE, TYRAMINE AND COCAINE ON AORTIC STRIPS OF RABBIT AND LEFT ATRIA OF GUINEA PIG AND CAT. J Pharmacol Exp Ther (1963) 2.36
Hepatorenal factors in circulatory homeostasis. IV. Tissue origins of the vasotropic principles, VEM and VDM, which appear during evolution of hemorrhagi and tourniquet shock. Circulation (1951) 2.34
Catecholamine content of the cat nicitating membrane following procedures sensitizing it to norepinephrine. J Pharmacol Exp Ther (1962) 1.77
THE EFFECTS OF VARIOUS DRUGS ON CALCIUM EXCHANGE IN THE ISOLATED GUINEA-PIG LEFT AURICLE. J Pharmacol Exp Ther (1964) 1.50
The determination of inorganic phosphate and creatine phosphate in tissue extracts. J Biol Chem (1956) 1.45
The photoactivated relaxation of smooth muscle of rabbit aorta. J Gen Physiol (1961) 1.42
THE EFFECTS OF FREQUENCY OF STIMULATION AND CALCIUM CONCENTRATION ON CA45 EXCHANGE AND CONTRACTILITY ON THE ISOLATED GUINEA-PIG AURICLE. J Pharmacol Exp Ther (1964) 1.34
THE EFFECTS OF EXTERNAL CALCIUM CONCENTRATION ON THE DISTRIBUTION AND EXCHANGE OF CALCIUM IN RESTING AND BEATING GUINEA-PIG AURICLES. J Pharmacol Exp Ther (1964) 1.21
ACTION POTENTIALS OF GUINEA PIG ATRIA UNDER CONDITIONS WHICH ALTER CONTRACTION. Am J Physiol (1964) 1.07
Effects of acetylcholine and epinephrine on the contractile strength and action potential of electrically driven guinea pig atria. J Pharmacol Exp Ther (1960) 0.99
Release of autonomic mediators in cardiac tissue by suprathreshold stimulation. Science (1959) 0.92
High energy phosphates and the force of contraction of cardiac muscle. Circulation (1961) 0.88
THE SYMPATHOMIMETIC ACTION OF BRETYLIUM OF ISOLATED ATRIA AND AORTIC SMOOTH MUSCLE. J Pharmacol Exp Ther (1964) 0.88
The high energy phosphate content of cardiac muscle under various experimental conditions which alter contractile strength. J Pharmacol Exp Ther (1958) 0.86
Utilization of compounds of Krebs cycle for contraction energy by rabbit intestinal smooth muscle. Am J Physiol (1952) 0.85
Effect of anoxia on contractility and metabolism of intestinal smooth muscle. Am J Physiol (1950) 0.82
Effect of pH on contractile activity of rabbit intestinal smooth muscle with and without added substrates. Am J Physiol (1951) 0.77
The effect of succinate on respiration and certain metabolic processes of mammalian tissues at low oxygen tensions in vitro. J Biol Chem (1948) 0.75
Infra-red absorption spectra of steroids; progesterone and pregnane derivatives. J Biol Chem (1947) 0.75
Experimental shock; the relation of metabolic derangements of liver and kidney to vascular reactions. Interne (1946) 0.75
Hepato-renal factors in circulatory hemeostasis; the influence of humoral factors of hepato-renal origin on the vascular reactions to hemorrhage. Ann N Y Acad Sci (1948) 0.75
The effect of sodium fluoroacetate on the contractility and metabolism of intestinal smooth muscle. J Pharmacol Exp Ther (1950) 0.75
Hepatorenal factors in circulatory homeostasis; an hepatic enzyme system which inactivates an hepatic vaso-depressor. Fed Proc (1947) 0.75
Sources of energy for intestinal smooth muscle contraction. Proc Soc Exp Biol Med (1946) 0.75
Effect of anoxia on contractility and metabolism of intestinal smooth muscle. Fed Proc (1948) 0.75
PASSIVE TRANSFER OF DELAYED HYPERSENSITIVITY WITH IODINE-131-LABELED SERUM. Jpn J Tuberc Chest Dis (1963) 0.75
Infra-red absorption spectra of steroids; adrenal cortical hormones and related steroids. J Biol Chem (1947) 0.75
Infra-red absorption spectra of steroids; estrogens. J Biol Chem (1946) 0.75