Is a long-term high-intensity exercise program effective and safe in patients with rheumatoid arthritis? Results of a randomized controlled trial.

PubWeight™: 1.92‹?› | Rank: Top 3%

🔗 View Article (PMID 13130460)

Published in Arthritis Rheum on September 01, 2003

Authors

Zuzana de Jong1, Marten Munneke, Aeilko H Zwinderman, Herman M Kroon, Annemarie Jansen, Karel H Ronday, Dirkjan van Schaardenburg, Ben A C Dijkmans, Cornelia H M Van den Ende, Ferdinand C Breedveld, Theodora P M Vliet Vlieland, Johanna M W Hazes

Author Affiliations

1: Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands. z.de_jong@lumc.nl

Associated clinical trials:

The Effects of a Six-week Exercise Programme Undertaken by Women With Rheumatoid Arthritis | NCT02819830

Rheumatoid Arthritis Patients in Training (RAPIT) | NCT00434200

Effects of Kinesiotaping for Hands Function in Rheumatoid Arthritis | NCT05039242

Articles citing this

Long term high intensity exercise and damage of small joints in rheumatoid arthritis. Ann Rheum Dis (2004) 1.73

A pragmatic randomised controlled trial of hydrotherapy and land exercises on overall well being and quality of life in rheumatoid arthritis. BMC Musculoskelet Disord (2007) 1.64

Benefits of exercise in rheumatoid arthritis. J Aging Res (2011) 1.25

Rheumatoid arthritis and cardiovascular disease. Am Heart J (2013) 1.14

Vascular function and inflammation in rheumatoid arthritis: the role of physical activity. Open Cardiovasc Med J (2010) 0.94

The effects of strength and endurance training in patients with rheumatoid arthritis. Clin Rheumatol (2010) 0.91

A systematic review of the effects of dynamic exercise in rheumatoid arthritis. Rheumatol Int (2009) 0.89

Exploring Tai Chi in rheumatoid arthritis: a quantitative and qualitative study. BMC Musculoskelet Disord (2010) 0.87

Effects of strengthening and aerobic exercises on pain severity and function in patients with knee rheumatoid arthritis. Int J Prev Med (2012) 0.84

Health status, physical disability, and obesity among adult Mississippians with chronic joint symptoms or doctor-diagnosed arthritis: findings from the Behavioral Risk Factor Surveillance System, 2003. Prev Chronic Dis (2008) 0.83

Long-term follow-up of a high-intensity exercise program in patients with rheumatoid arthritis. Clin Rheumatol (2009) 0.83

Promoting physical activity in patients with rheumatoid arthritis: rheumatologists' and health professionals' practice and educational needs. Clin Rheumatol (2011) 0.83

The effect of conditioning exercise on the health status and pain in patients with rheumatoid arthritis: a randomized controlled clinical trial. Int J Community Based Nurs Midwifery (2014) 0.82

The effects of high intensity interval training in women with rheumatic disease: a pilot study. Eur J Appl Physiol (2015) 0.79

Effects of isotonic and isometric hand exercises on pain, hand functions, dexterity and quality of life in women with rheumatoid arthritis. Rheumatol Int (2013) 0.79

Successfully living with chronic arthritis. The role of the allied health professionals. Clin Rheumatol (2005) 0.78

Who makes it to the base? Selection procedure for a physical activity trial targeting people with rheumatoid arthritis. Arthritis Care Res (Hoboken) (2014) 0.78

A prospective pilot study to evaluate an animated home-based physical exercise program as a treatment option for patients with rheumatoid arthritis. BMC Musculoskelet Disord (2016) 0.78

The exercise prescription in rheumatoid arthritis: primum non nocere. Arthritis Rheum (2003) 0.77

The future of rheumatoid arthritis and hand surgery - combining evolutionary pharmacology and surgical technique. Open Orthop J (2012) 0.77

Dynamic exercises in patients with rheumatoid arthritis. Ann Rheum Dis (2004) 0.76

Strategies for making analgesia safer: the role of comparative effectiveness research. Arthritis Rheum (2010) 0.76

Randomised controlled trial examining the effect of exercise in people with rheumatoid arthritis taking anti-TNFα therapy medication. BMC Musculoskelet Disord (2011) 0.75

An outsourced health-enhancing physical activity programme for people with rheumatoid arthritis: exploration of adherence and response. Rheumatology (Oxford) (2014) 0.75

Physical activity and risk of rheumatoid arthritis in women: a population-based prospective study. Arthritis Res Ther (2015) 0.75

The beneficial effects of Tai Chi exercise on endothelial function and arterial stiffness in elderly women with rheumatoid arthritis. Arthritis Res Ther (2015) 0.75

Multireader assessment as an alternative to reference assessment to improve the detection of radiographic progression in a large longitudinal cohort of rheumatoid arthritis (ESPOIR). RMD Open (2017) 0.75

Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity. BMC Musculoskelet Disord (2017) 0.75

Pragmatic assessment of exercise in routine care using an MDHAQ: associations with changes in RAPID3 and other clinical variables. Arthritis Res Ther (2016) 0.75

Articles by these authors

2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum (2010) 18.82

Simvastatin with or without ezetimibe in familial hypercholesterolemia. N Engl J Med (2008) 14.01

2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis (2010) 12.12

Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis (2010) 10.97

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Ann Rheum Dis (2013) 10.92

Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol (2005) 10.56

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis (2010) 10.03

Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors. Arthritis Rheum (2004) 7.79

Progression of radiologic damage in patients with rheumatoid arthritis in clinical remission. Arthritis Rheum (2004) 7.13

Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia. N Engl J Med (2011) 6.76

Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial. Lancet (2008) 6.16

COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention. Arthritis Rheum (2002) 5.57

How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis. Arthritis Rheum (2002) 5.33

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins. Arthritis Rheum (2005) 5.18

Comparison of treatment strategies in early rheumatoid arthritis: a randomized trial. Ann Intern Med (2007) 5.05

Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis. JAMA (2012) 4.49

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis. N Engl J Med (2006) 3.80

Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trial. Arthritis Rheum (2007) 3.66

Molecular basis of bortezomib resistance: proteasome subunit beta5 (PSMB5) gene mutation and overexpression of PSMB5 protein. Blood (2008) 3.65

The safety and efficacy of a JAK inhibitor in patients with active rheumatoid arthritis: Results of a double-blind, placebo-controlled phase IIa trial of three dosage levels of CP-690,550 versus placebo. Arthritis Rheum (2009) 3.58

Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging--a meta-analysis. Radiology (2004) 3.55

Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum (2006) 3.51

ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial. JAMA (2009) 3.33

A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: how to guide individual treatment decisions. Arthritis Rheum (2007) 3.23

Internet-based physical activity interventions: a systematic review of the literature. J Med Internet Res (2007) 3.14

Quantifying the association between gene expressions and DNA-markers by penalized canonical correlation analysis. Stat Appl Genet Mol Biol (2008) 3.13

Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues. Arthritis Rheum (2003) 3.05

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search. Ann Rheum Dis (2010) 2.91

"Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids. Am J Respir Crit Care Med (2004) 2.77

Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up. JAMA (2011) 2.73

Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis. Arthritis Res Ther (2005) 2.69

Clinical response to adalimumab: relationship to anti-adalimumab antibodies and serum adalimumab concentrations in rheumatoid arthritis. Ann Rheum Dis (2007) 2.67

Does rheumatoid arthritis equal diabetes mellitus as an independent risk factor for cardiovascular disease? A prospective study. Arthritis Rheum (2009) 2.55

The HLA-DRB1 shared epitope alleles are primarily a risk factor for anti-cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis. Arthritis Rheum (2006) 2.46

Rheumatoid factor and antibodies to cyclic citrullinated Peptide differentiate rheumatoid arthritis from undifferentiated polyarthritis in patients with early arthritis. J Rheumatol (2002) 2.42

Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study. Lancet (2002) 2.39

Losartan reduces aortic dilatation rate in adults with Marfan syndrome: a randomized controlled trial. Eur Heart J (2013) 2.37

Early effects of rituximab on the synovial cell infiltrate in patients with rheumatoid arthritis. Arthritis Rheum (2007) 2.35

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis. Ann Rheum Dis (2013) 2.33

Preoperative thresholds for pulmonary valve replacement in patients with corrected tetralogy of Fallot using cardiovascular magnetic resonance. Circulation (2007) 2.31

Risk factors for malignant ventricular arrhythmias in lamin a/c mutation carriers a European cohort study. J Am Coll Cardiol (2012) 2.28

Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study. Arthritis Res Ther (2006) 2.28

Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk. Ann Intern Med (2007) 2.26

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis. Arthritis Rheum (2004) 2.25

Cost-utility analysis of treatment strategies in patients with recent-onset rheumatoid arthritis. Arthritis Rheum (2009) 2.24

Magnetic resonance imaging to assess the hemodynamic effects of pulmonary valve replacement in adults late after repair of tetralogy of fallot. Circulation (2002) 2.14

Exhaled breath profiling enables discrimination of chronic obstructive pulmonary disease and asthma. Am J Respir Crit Care Med (2009) 2.12

Intramuscular administration of AAV1-lipoprotein lipase S447X lowers triglycerides in lipoprotein lipase-deficient patients. Arterioscler Thromb Vasc Biol (2008) 2.10

Risk of deep vein thrombosis and pulmonary embolism in asthma. Eur Respir J (2012) 2.08

Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis. CMAJ (2008) 2.06

Creatine kinase is associated with failure of hypertension treatment. J Hypertens (2013) 2.02

Prevalence of and risk factors for low bone mineral density and vertebral fractures in patients with systemic lupus erythematosus. Arthritis Rheum (2005) 2.01

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes. Arthritis Rheum (2006) 2.00

Importance of the first link: description and recognition of an out-of-hospital cardiac arrest in an emergency call. Circulation (2009) 2.00

The changing epidemiology of congenital heart disease. Nat Rev Cardiol (2010) 1.99

The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Phase 2 methodological report. Arthritis Rheum (2010) 1.94

In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell (2010) 1.94

Increased levels of C-reactive protein in serum from blood donors before the onset of rheumatoid arthritis. Arthritis Rheum (2004) 1.94

Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis. Ann Rheum Dis (2011) 1.93

Comparative assessment of leflunomide and methotrexate for the treatment of rheumatoid arthritis, by dynamic enhanced magnetic resonance imaging. Arthritis Rheum (2002) 1.92

Evidence-based analysis of physical therapy in Parkinson's disease with recommendations for practice and research. Mov Disord (2007) 1.90

Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation (2002) 1.89

Tumor markers in the diagnosis of primary bladder cancer. A systematic review. J Urol (2003) 1.86

Colorectal liver metastases: CT, MR imaging, and PET for diagnosis--meta-analysis. Radiology (2005) 1.84

The presence or absence of antibodies to infliximab or adalimumab determines the outcome of switching to etanercept. Ann Rheum Dis (2010) 1.81

Consequences of rheumatoid arthritis for performance of social roles--a literature review. J Rheumatol (2007) 1.80

Vitamin D deficiency does not increase the risk of rheumatoid arthritis: comment on the article by Merlino et al. Arthritis Rheum (2006) 1.79

Host genetic susceptibility to pneumococcal and meningococcal disease: a systematic review and meta-analysis. Lancet Infect Dis (2008) 1.78

Genetic inflammatory factors predict restenosis after percutaneous coronary interventions. Circulation (2005) 1.78

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis. Ann Rheum Dis (2012) 1.78

The "posture second" strategy: a review of wrong priorities in Parkinson's disease. J Neurol Sci (2006) 1.78

Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients. Arthritis Rheum (2009) 1.77

Limited efficacy of conventional DMARDs after initial methotrexate failure in patients with recent onset rheumatoid arthritis treated according to the disease activity score. Ann Rheum Dis (2007) 1.77

Detection of vein graft disease using high-resolution magnetic resonance angiography. Circulation (2002) 1.76

MRI assessment of knee osteoarthritis: Knee Osteoarthritis Scoring System (KOSS)--inter-observer and intra-observer reproducibility of a compartment-based scoring system. Skeletal Radiol (2004) 1.76

Differential response of the rheumatoid factor and anticitrullinated protein antibodies during adalimumab treatment in patients with rheumatoid arthritis. J Rheumatol (2008) 1.75

Frequent mutation in the ABCC6 gene (R1141X) is associated with a strong increase in the prevalence of coronary artery disease. Circulation (2002) 1.74

Coronary collaterals improve prognosis in patients with ischemic heart disease. Int J Cardiol (2008) 1.74

Minimal disease activity for rheumatoid arthritis: a preliminary definition. J Rheumatol (2005) 1.70

Management of inflammatory bowel disease in pregnancy. J Crohns Colitis (2012) 1.69

Enchondromatosis: insights on the different subtypes. Int J Clin Exp Pathol (2010) 1.67

Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism. Arthritis Rheum (2002) 1.67

Internet-based tapering of oral corticosteroids in severe asthma: a pragmatic randomised controlled trial. Thorax (2011) 1.66

Paraoxonase variants relate to 10-year risk in coronary artery disease: impact of a high-density lipoprotein-bound antioxidant in secondary prevention. J Am Coll Cardiol (2009) 1.65

Acute appendicitis: meta-analysis of diagnostic performance of CT and graded compression US related to prevalence of disease. Radiology (2008) 1.65

Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheum (2008) 1.64

The effect of TNF-alpha blocking therapy on lipid levels in rheumatoid arthritis: a meta-analysis. Semin Arthritis Rheum (2011) 1.63