Published in J Pharmacol Exp Ther on March 01, 1957
Gastric secretion in relation to mucosal blood flow studied by a clearance technic. J Clin Invest (1966) 5.58
Radioactive aniline clearance from canine gastric pouches for the measurement of gastric mucosal blood flow. Br J Pharmacol (1971) 4.26
Gastric mucosal blood flow during pentagastrin- and histamine-stimulated acid secretion in the rat. Br J Pharmacol (1973) 2.55
The measurement of dog gastric mucosal blood flow by radioactive aniline clearance compared with amidopyrine clearance. J Physiol (1973) 2.07
Gastric blood flow in anaesthetized cats. J Physiol (1968) 1.93
Nitazoxanide, a potential drug for eradication of Helicobacter pylori with no cross-resistance to metronidazole. Antimicrob Agents Chemother (1998) 1.23
Retracted Study of the factors that cause specific transformation in cultures of lymphocytes from patients with quinine- and quinidine-induced immune thrombocytopenia. J Clin Invest (1980) 1.19
The role of pH gradient in the distribution of ammonia between blood and cerebrospinal fluid, brain and muscle. J Clin Invest (1959) 1.11
Pepsin secretion, gastric motility and mucosal blood flow in the anaesthetized cat. J Physiol (1971) 1.08
The gastrointestinal absorption of drugs in man: a review of current concepts and methods of investigation. Br J Clin Pharmacol (1985) 1.05
Lactulose. Gut (1970) 1.04
Transfer of propionate by rat small intestine in vitro. J Physiol (1966) 1.01
Does gastric aminopyrine clearance reflect gastric mucosal blood flow or parietal cell function? Gut (1981) 0.98
Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats. Gut (2002) 0.97
Modeling kinetics of subcellular disposition of chemicals. Chem Rev (2009) 0.96
Effect of nicotine on gastric mucosal blood flow and acid secretion. Gut (1982) 0.95
Partial protection against multiple RT-SHIV162P3 vaginal challenge of rhesus macaques by a silicone elastomer vaginal ring releasing the NNRTI MC1220. J Antimicrob Chemother (2012) 0.95
Testing physical models of passive membrane permeation. J Chem Inf Model (2012) 0.93
In vitro assessment of gastric mucosal transfer of anti-Helicobacter therapeutic agents. Antimicrob Agents Chemother (1997) 0.89
Evolution of stimulants to treat ADHD: transdermal methylphenidate. Hum Psychopharmacol (2009) 0.88
Effect of ammonium chloride and urea infusions on ammonium levels and acidity of gastric juice. Gut (1965) 0.88
Ammonia movement in the small intestine: preferential transport by the ileum. J Clin Invest (1967) 0.88
Relative activity of some inhibitors of mono-amine oxidase in potentiating the action of tryptamine in vitro and in vivo. Br J Pharmacol Chemother (1961) 0.87
In vitro-in vivo correlation: perspectives on model development. Int J Pharm (2011) 0.87
Mechanisms of lipid loss from the small intestinal mucosa. Gut (1975) 0.85
Solid-state NMR spectroscopic studies on the interaction of sorbic acid with phospholipid membranes at different pH levels. Magn Reson Chem (2009) 0.83
The effect of E. coli STa enterotoxin on the absorption of weakly dissociable drugs from rat proximal jejunum in vivo. Br J Pharmacol (1990) 0.82
Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen. Br J Pharmacol (2010) 0.80
Effect of 2-diethylaminoethyl-2,2-diphenylvalerate hydrochloride (SKF 525-A) on sulphacetamide distribution and excretion in rats. Br J Pharmacol (1973) 0.78
Penetration of chemicals into the oocyte, uterine fluid, and preimplantation blastocyst. Environ Health Perspect (1978) 0.77
Influence of antisecretory drugs on Helicobacter pylori eradication rates. Gut (2004) 0.75
Effect of surfactants and pH on naltrexone (NTX) permeation across buccal mucosa. Int J Pharm (2011) 0.75
Oral absorption profiles of sulfonamides in Shiba goats: a comparison among sulfadimidine, sulfadiazine and sulfanilamide. J Vet Med Sci (2016) 0.75
Does transbilayer diffusion have a role in membrane transport of drugs? Drug Discov Today (2012) 0.75
Rigorous incorporation of tautomers, ionization species, and different binding modes into ligand-based and receptor-based 3D-QSAR methods. Curr Pharm Des (2013) 0.75
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery. Proc Natl Acad Sci U S A (2017) 0.75
A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity. J Biol Chem (1952) 18.27
A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther (1959) 16.61
The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest (1955) 6.74
Ascorbic acid in aromatic hydroxylation. I. A model system for aromatic hydroxylation. J Biol Chem (1954) 5.08
Identification and assay of serotonin in brain. J Pharmacol Exp Ther (1956) 4.17
Active transport of chloride by isolated frog gastric epithelium; origin of the gastric mucosal potential. Am J Physiol (1955) 3.65
The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 3.60
A chemical method for the determination of free choline in plasma. J Biol Chem (1953) 3.57
Norepinephrine depletion as a possible mechanism of action of guanethidine (SU 5864), a new hypotensive agent. Proc Soc Exp Biol Med (1960) 3.26
On the mechanism of intestinal absorption of drugs. J Pharmacol Exp Ther (1959) 3.16
Some physico-chemical factors in drug action. J Pharm Pharmacol (1957) 3.13
The fate of antipyrine in man. J Pharmacol Exp Ther (1950) 3.05
Serotonin release as a possible mechanism of reserpine action. Science (1955) 3.03
Ionic transfer across the isolated frog large intestine. J Gen Physiol (1959) 3.00
The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. J Biol Chem (1953) 2.98
Ascorbic acid in aromatic hydroxylation. II. Products formed by reaction of substrates with ascorbic acid, ferrous ion, and oxygen. J Biol Chem (1954) 2.78
INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS. J Pharmacol Exp Ther (1965) 2.77
A concept for a role of serotonin and norepinephrine as chemical mediators in the brain. Ann N Y Acad Sci (1957) 2.71
Absorption of drugs from the rat small intestine. J Pharmacol Exp Ther (1958) 2.62
The fate of aminopyrine (pyramidon) in man and methods for the estimation of aminopyrine and its metabolites in biological material. J Pharmacol Exp Ther (1950) 2.54
The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J Pharmacol Exp Ther (1957) 2.46
The fate of pentobarbital in man and dog and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 2.38
Identification and chemical assay of norepinephrine in brain and other tissues. J Pharmacol Exp Ther (1958) 2.37
Enzymatic metabolism of drugs and other foreign compounds. Annu Rev Biochem (1958) 2.36
Serotonin as a mediator of reserpine action in brain. J Pharmacol Exp Ther (1956) 2.26
A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671. J Pharmacol Exp Ther (1957) 2.20
Detoxication of drugs and other foreign compounds by liver microsomes. Science (1955) 2.20
Estimation of intracellular water in man. Am J Physiol (1950) 2.14
Evidence that serotonin has a role in brain function. Science (1955) 2.13
Pharmacological consequences of the selective release of peripheral norepinephrine by syrosingopine (Su 3118). J Pharmacol Exp Ther (1960) 2.10
The fate of thiopental in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1950) 2.10
Interaction of reserpine, serotonin, and lysergic acid diethylamide in brain. Science (1955) 1.99
Absorption of drugs from the stomach. I. The rat. J Pharmacol Exp Ther (1957) 1.86
Absorption of drugs from the stomach. II. The human. J Pharmacol Exp Ther (1957) 1.85
Mechanism of the potentiating action of beta-diethylaminoethyl diphenylpropylacetate. J Pharmacol Exp Ther (1954) 1.78
Enzymatic dealkylation of aminopyrine (pyramidon) and other alkylamines. J Biol Chem (1955) 1.77
The metabolic fate of phenylbutazone (butazolidin) in man. J Pharmacol Exp Ther (1955) 1.76
A PRACTICAL AND SIMPLE EQUIVALENT FOR STUDENT'S T TEST OF STATISTICAL SIGNIFICANCE. J Lab Clin Med (1964) 1.69
Biochemical and pharmacological studies of RO 1-9569 (tetrabenazine), a nonindole tranquilizing agent with reserpine-like effects. J Pharmacol Exp Ther (1959) 1.63
The physiological disposition and metabolic fate of cortisone in man. J Clin Invest (1957) 1.62
On the mechanism of drug potentiation by iproniazid (2-isopropyl-1-isonicotinyl hydrazine). J Pharmacol Exp Ther (1956) 1.61
Physiological disposition and fate of chlorpromazine and a method for its estimation in biological material. J Pharmacol Exp Ther (1956) 1.59
BINDING AND RELEASE OF METARAMINOL: MECHANISM OF NOREPINEPHRINE DEPLETION BY ALPHA-METHYL-M-TYROSINE AND RELATED AGENTS. J Pharmacol Exp Ther (1964) 1.56
The enzymatic metabolism of hexobarbital (evipal). J Pharmacol Exp Ther (1955) 1.56
Possible interrelationship between release of brain norepinephrine and serotonin by reserpine. Science (1957) 1.54
Release of serotonin and catecholamines by drugs. Pharmacol Rev (1962) 1.53
Total body water in man. Am J Physiol (1950) 1.50
Inhibitory effects of beta-diethylaminoethyl diphenylpropylacetate on a variety of drug metabolic pathways in vitro. J Pharmacol Exp Ther (1954) 1.49
Biliary excretion of inulin, sucrose, and mannitol: analysis of bile formation. Am J Physiol (1961) 1.47
The importance of dissociaton constant and lipid-solubility in influencing the passage of drugs into the cerebrospinal fluid. J Pharmacol Exp Ther (1960) 1.47
RECENT VIEWS ON MECHANISMS FOR LOWERING SYMPATHETIC TONE. Circulation (1963) 1.44
On the mechanism of antidepressant action of imipraminelike drugs. Ann N Y Acad Sci (1962) 1.42
The use of procaine amide in cardiac arrhythmias. Circulation (1951) 1.42
Pathways of drug metabolism. J Pharm Pharmacol (1956) 1.41
Biochemical and pharmacological effects of the monoamine oxidase inhibitors, iproniazid, 1-phenyl-2-hydrazinopropane (JB 516) and 1-phenyl-3-hydrazinobutane (JB 835). J Pharmacol Exp Ther (1960) 1.41
The mechanism of serotonin and catecholamine uptake by platelets. J Pharmacol Exp Ther (1959) 1.40
Role of brain serotonin in reserpine action. Ann N Y Acad Sci (1957) 1.40
Structural requirements for bretylium and guanethidine-like activity. Life Sci (1962) 1.39
Release of serotonin from blood platelets by reserpine in vitro. J Pharmacol Exp Ther (1957) 1.39
The enzymatic reduction of chloramphenicol, p-nitrobenzoic acid and other aromatic nitro compounds in mammals. J Pharmacol Exp Ther (1957) 1.38
Metabolism of drugs in subjects with Laennec's cirrhosis. Med Exp Int J Exp Med (1959) 1.38
Postoperative pain; its use in the comparative evaluation of analgesics. Surgery (1952) 1.38
Assay of serotonin and related metabolites, enzymes, and drugs. Methods Biochem Anal (1958) 1.37
Microanalytical procedures for fluorometric assay of brain DOPA-5HTP decarboxylase, norepinephrine and serotonin, and a detailed mapping of decarboxylase activity in brain. J Neurochem (1961) 1.35
The physiological disposition and biotransformation of dibenamine and a method for its estimation in biological tissues. J Pharmacol Exp Ther (1952) 1.35
RELEASE OF METARAMINOL (ARAMINE) FROM THE HEART BY SYMPATHETIC NERVE STIMULATION. Science (1964) 1.33
The role of body fat in limiting the duration of action of thiopental. J Pharmacol Exp Ther (1952) 1.32
MECHANISM OF ACTION OF RESERPINE AND INSULIN ON GASTRIC AMINES AND GASTRIC ACID SECRETION, AND THE EFFECT OF MONOAMINE OXIDASE INHIBITION. J Pharmacol Exp Ther (1963) 1.28
Reserpine and guanethidine action on peripheral stores of catecholamines. Life Sci (1962) 1.27
Observations on the antirheumatic and physiologic effects of phenylbutazone (butazolidin) and some comparisons with cortisone. Am J Med (1954) 1.22
Effects of reserpine and cold-exposure on pituitary-adrenocortical function in rats. J Pharmacol Exp Ther (1961) 1.21
The alimentary tract. Annu Rev Physiol (1960) 1.20
THE ACTIONS OF RESERPINE, GUANETHIDINE AND METARAMINOL ON CARDIAC CATECHOLAMINE STORES. Life Sci (1964) 1.18
Enzymatic reduction of prontosil and other azo dyes. J Pharmacol Exp Ther (1957) 1.17
The physiological disposition of dicumarol in man. J Pharmacol Exp Ther (1950) 1.17
Interaction of monoamine oxidase inhibitors with physiological and biochemical mechanisms in brain. Ann N Y Acad Sci (1959) 1.17
Physiochemical aspects of hydrochloric acid formation. Am J Dig Dis (1959) 1.16
Role for ganglionic norepinephrine in sympathetic synaptic transmission. Science (1961) 1.15
Interaction of drugs with norepinephrine in the brain. Pharmacol Rev (1959) 1.15
Interaction of serotonin and lysergic acid diethylamide (LSD) in the central nervous system. Experientia (1955) 1.14