Published in J Pharm Pharmacol on June 01, 1957
Antigenic modulation of Bordetella pertussis. J Hyg (Lond) (1960) 4.61
The relative activities of some tryptamine analogues on the isolated rat stomach strip preparation. Br J Pharmacol Chemother (1959) 3.17
Barbiturates and oxidative phosphorylation. Biochem J (1960) 2.45
The modification by physostigmine of some effects of nicotine on bar-pressing behaviour of rats. Br J Pharmacol Chemother (1968) 1.86
Studies on the coumarin anticoagulant drugs: interaction of human plasma albumin and warfarin sodium. J Clin Invest (1967) 1.67
The metabolism of thalidomide: the fate of thalidomide and some of its hydrolysis products in various species. Br J Pharmacol Chemother (1965) 1.62
Effects of nicotine and some nicotine-like compounds injected into the cerebral ventricles of the cat. Br J Pharmacol Chemother (1966) 1.54
Comparative detoxication. 7. The metabolism of chlorobenzene in locusts: excretion of unchanged chlorobenzene and cysteine conjugates. Biochem J (1960) 1.33
The passage of ammonia across the blood-brain-barrier and its relation to blood pH. J Clin Invest (1958) 1.28
Transfer of short-chain fatty acids by the intestine. J Physiol (1960) 1.28
Binding of antibiotics to bovine and ovine serum. Antimicrob Agents Chemother (1972) 1.17
Quantitative studies of the passage of different substances out of the cerebrospinal fluid. J Physiol (1962) 1.17
Factors influencing the aggressiveness elicited by marihuana in food-deprived rats. Br J Pharmacol (1972) 1.11
Binding of digitoxin and some related cardenolides to human plasma proteins. J Clin Invest (1969) 1.08
Absorption, metabolism and elimination of pempidine in the rat. Br J Pharmacol Chemother (1959) 1.08
Comparison of ceftazidime and cefamandole pharmacokinetics and blister fluid concentrations. Antimicrob Agents Chemother (1981) 1.04
Comparative detoxication. 8. The metabolism of chlorobenzene in locusts: phenolic metabolites, a comparison with some vertebrate species. Biochem J (1960) 1.02
The effect of dosage form upon the gastrointestinal absorption rate of salicylates. Can Med Assoc J (1961) 0.95
The biological disposition of morphine and its surrogates. Bull World Health Organ (1962) 0.94
The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam. Br J Clin Pharmacol (1982) 0.93
Transport characteristics of folates in cerebrospinal fluid; a study utilizing doubly labeled 5-methyltetrahydrofolate and 5-formyltetrahydrofolate. J Clin Invest (1971) 0.92
Drug transporters in pharmacokinetics. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.91
Relative activity of some inhibitors of mono-amine oxidase in potentiating the action of tryptamine in vitro and in vivo. Br J Pharmacol Chemother (1961) 0.87
A possible explanation for the peripheral selectivity of a novel non-steroidal pure antiandrogen, Casodex (ICI 176,334). Br J Cancer (1989) 0.79
The transfer of drugs across the placenta. Proc R Soc Med (1969) 0.77
Salicylic acid transport in Ricinus communis involves a pH-dependent carrier system in addition to diffusion. Plant Physiol (2009) 0.75
Problems in the Designing of Antimetabolites. Yale J Biol Med (1960) 0.75
[Drug uptake and catabolism in the fetal period]. Arch Gynakol (1971) 0.75
A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity. J Biol Chem (1952) 18.27
The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest (1955) 6.74
Ascorbic acid in aromatic hydroxylation. I. A model system for aromatic hydroxylation. J Biol Chem (1954) 5.08
Identification and assay of serotonin in brain. J Pharmacol Exp Ther (1956) 4.17
The gastric secretion of drugs: a pH partition hypothesis. J Pharmacol Exp Ther (1957) 3.99
Active transport of chloride by isolated frog gastric epithelium; origin of the gastric mucosal potential. Am J Physiol (1955) 3.65
The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 3.60
A chemical method for the determination of free choline in plasma. J Biol Chem (1953) 3.57
Norepinephrine depletion as a possible mechanism of action of guanethidine (SU 5864), a new hypotensive agent. Proc Soc Exp Biol Med (1960) 3.26
On the mechanism of intestinal absorption of drugs. J Pharmacol Exp Ther (1959) 3.16
The fate of antipyrine in man. J Pharmacol Exp Ther (1950) 3.05
Serotonin release as a possible mechanism of reserpine action. Science (1955) 3.03
Ionic transfer across the isolated frog large intestine. J Gen Physiol (1959) 3.00
The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. J Biol Chem (1953) 2.98
Ascorbic acid in aromatic hydroxylation. II. Products formed by reaction of substrates with ascorbic acid, ferrous ion, and oxygen. J Biol Chem (1954) 2.78
INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS. J Pharmacol Exp Ther (1965) 2.77
A concept for a role of serotonin and norepinephrine as chemical mediators in the brain. Ann N Y Acad Sci (1957) 2.71
Absorption of drugs from the rat small intestine. J Pharmacol Exp Ther (1958) 2.62
The fate of aminopyrine (pyramidon) in man and methods for the estimation of aminopyrine and its metabolites in biological material. J Pharmacol Exp Ther (1950) 2.54
The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J Pharmacol Exp Ther (1957) 2.46
The fate of pentobarbital in man and dog and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 2.38
Enzymatic metabolism of drugs and other foreign compounds. Annu Rev Biochem (1958) 2.36
Serotonin as a mediator of reserpine action in brain. J Pharmacol Exp Ther (1956) 2.26
A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671. J Pharmacol Exp Ther (1957) 2.20
Detoxication of drugs and other foreign compounds by liver microsomes. Science (1955) 2.20
Estimation of intracellular water in man. Am J Physiol (1950) 2.14
Evidence that serotonin has a role in brain function. Science (1955) 2.13
Pharmacological consequences of the selective release of peripheral norepinephrine by syrosingopine (Su 3118). J Pharmacol Exp Ther (1960) 2.10
The fate of thiopental in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1950) 2.10
Interaction of reserpine, serotonin, and lysergic acid diethylamide in brain. Science (1955) 1.99
Absorption of drugs from the stomach. I. The rat. J Pharmacol Exp Ther (1957) 1.86
Absorption of drugs from the stomach. II. The human. J Pharmacol Exp Ther (1957) 1.85
Mechanism of the potentiating action of beta-diethylaminoethyl diphenylpropylacetate. J Pharmacol Exp Ther (1954) 1.78
Enzymatic dealkylation of aminopyrine (pyramidon) and other alkylamines. J Biol Chem (1955) 1.77
The metabolic fate of phenylbutazone (butazolidin) in man. J Pharmacol Exp Ther (1955) 1.76
A PRACTICAL AND SIMPLE EQUIVALENT FOR STUDENT'S T TEST OF STATISTICAL SIGNIFICANCE. J Lab Clin Med (1964) 1.69
Biochemical and pharmacological studies of RO 1-9569 (tetrabenazine), a nonindole tranquilizing agent with reserpine-like effects. J Pharmacol Exp Ther (1959) 1.63
The physiological disposition and metabolic fate of cortisone in man. J Clin Invest (1957) 1.62
On the mechanism of drug potentiation by iproniazid (2-isopropyl-1-isonicotinyl hydrazine). J Pharmacol Exp Ther (1956) 1.61
Physiological disposition and fate of chlorpromazine and a method for its estimation in biological material. J Pharmacol Exp Ther (1956) 1.59
The enzymatic metabolism of hexobarbital (evipal). J Pharmacol Exp Ther (1955) 1.56
Possible interrelationship between release of brain norepinephrine and serotonin by reserpine. Science (1957) 1.54
Total body water in man. Am J Physiol (1950) 1.50
Inhibitory effects of beta-diethylaminoethyl diphenylpropylacetate on a variety of drug metabolic pathways in vitro. J Pharmacol Exp Ther (1954) 1.49
Biliary excretion of inulin, sucrose, and mannitol: analysis of bile formation. Am J Physiol (1961) 1.47
The importance of dissociaton constant and lipid-solubility in influencing the passage of drugs into the cerebrospinal fluid. J Pharmacol Exp Ther (1960) 1.47
RECENT VIEWS ON MECHANISMS FOR LOWERING SYMPATHETIC TONE. Circulation (1963) 1.44
On the mechanism of antidepressant action of imipraminelike drugs. Ann N Y Acad Sci (1962) 1.42
The use of procaine amide in cardiac arrhythmias. Circulation (1951) 1.42
Pathways of drug metabolism. J Pharm Pharmacol (1956) 1.41
Biochemical and pharmacological effects of the monoamine oxidase inhibitors, iproniazid, 1-phenyl-2-hydrazinopropane (JB 516) and 1-phenyl-3-hydrazinobutane (JB 835). J Pharmacol Exp Ther (1960) 1.41
The mechanism of serotonin and catecholamine uptake by platelets. J Pharmacol Exp Ther (1959) 1.40
Role of brain serotonin in reserpine action. Ann N Y Acad Sci (1957) 1.40
Structural requirements for bretylium and guanethidine-like activity. Life Sci (1962) 1.39
Release of serotonin from blood platelets by reserpine in vitro. J Pharmacol Exp Ther (1957) 1.39
The enzymatic reduction of chloramphenicol, p-nitrobenzoic acid and other aromatic nitro compounds in mammals. J Pharmacol Exp Ther (1957) 1.38
Metabolism of drugs in subjects with Laennec's cirrhosis. Med Exp Int J Exp Med (1959) 1.38
Postoperative pain; its use in the comparative evaluation of analgesics. Surgery (1952) 1.38
Assay of serotonin and related metabolites, enzymes, and drugs. Methods Biochem Anal (1958) 1.37
Microanalytical procedures for fluorometric assay of brain DOPA-5HTP decarboxylase, norepinephrine and serotonin, and a detailed mapping of decarboxylase activity in brain. J Neurochem (1961) 1.35
The physiological disposition and biotransformation of dibenamine and a method for its estimation in biological tissues. J Pharmacol Exp Ther (1952) 1.35
The role of body fat in limiting the duration of action of thiopental. J Pharmacol Exp Ther (1952) 1.32
Reserpine and guanethidine action on peripheral stores of catecholamines. Life Sci (1962) 1.27
Observations on the antirheumatic and physiologic effects of phenylbutazone (butazolidin) and some comparisons with cortisone. Am J Med (1954) 1.22
Effects of reserpine and cold-exposure on pituitary-adrenocortical function in rats. J Pharmacol Exp Ther (1961) 1.21
The alimentary tract. Annu Rev Physiol (1960) 1.20
THE ACTIONS OF RESERPINE, GUANETHIDINE AND METARAMINOL ON CARDIAC CATECHOLAMINE STORES. Life Sci (1964) 1.18
The physiological disposition of dicumarol in man. J Pharmacol Exp Ther (1950) 1.17
Enzymatic reduction of prontosil and other azo dyes. J Pharmacol Exp Ther (1957) 1.17
Interaction of monoamine oxidase inhibitors with physiological and biochemical mechanisms in brain. Ann N Y Acad Sci (1959) 1.17
Physiochemical aspects of hydrochloric acid formation. Am J Dig Dis (1959) 1.16
Role for ganglionic norepinephrine in sympathetic synaptic transmission. Science (1961) 1.15
Interaction of drugs with norepinephrine in the brain. Pharmacol Rev (1959) 1.15
Storage synthesis, and metabolism of monoamines in the developing brain. J Neurochem (1962) 1.14
Quinoline and its transformation products found in urine. J Biol Chem (1950) 1.14
Interaction of serotonin and lysergic acid diethylamide (LSD) in the central nervous system. Experientia (1955) 1.14
On the mechanism of action of reserpine: effect of reserpine on capacity of tissues to bind serotonin. J Pharmacol Exp Ther (1957) 1.13
Inhibition of drug metabolic pathways by the potentiating agent, 2, 4-dichloro-6-phenyl-phenoxyethyl diethylamine. J Pharmacol Exp Ther (1955) 1.11
Relationship between the lipid solubility of drugs and their oxidation by liver microsomes. Biochem Pharmacol (1959) 1.10
Biochemical pharmacological considerations of phenylbutazone and its analogues. Ann N Y Acad Sci (1960) 1.08
The biotransformation of ethyl biscoumacetate (tromexan) in man, rabbit and dog. J Pharmacol Exp Ther (1953) 1.08
The physiological disposition and cardiac effects of procaine amide. J Pharmacol Exp Ther (1951) 1.08
Inhibition of gastric acid secretion in the dog by the precursor of serotonin, 5-hydroxytryptophan. Gastroenterology (1958) 1.07
Evidence that tranquilizing action of reserpine is associated with change in brain serotonin and not in brain norepinephrine. J Pharmacol Exp Ther (1960) 1.07
Phenylbutazone metabolites: antirheumatic, sodium-retaining and uricosuric effects in man. J Pharmacol Exp Ther (1958) 1.07
Ascorbic acid in aromatic hydroxylation. III. Effect of ascorbic acid on hydroxylation of acetanilide, aniline and antipyrine in vivo. J Pharmacol Exp Ther (1954) 1.06
Depot fat as source of increased liver triglycerides after ethanol. Biochem Biophys Res Commun (1960) 1.05
Serotonin storage mechanism and its interaction with reserpine. Experientia (1958) 1.04
Passage of lipid-insoluble substances from cerebrospinal fluid to blood. J Pharmacol Exp Ther (1962) 1.03
A spectrophotofluorometric study of compounds of biological interest. Arch Biochem Biophys (1957) 1.03
Effect of serotonin (5-hydroxytryptamine) and related compounds on gastric secretion and intestinal motility in the dog. Gastroenterology (1957) 1.02
Isolation from rat brain of a metabolic product, desmethylimipramine, that mediates the antidepressant activity of imipramine (Tofranil). Experientia (1961) 1.01
The physiological disposition and fate of meperidine (demerol) in man and a method for its estimation in plasma. J Pharmacol Exp Ther (1955) 1.01
Metabolites of pamaquine in urine. Proc Soc Exp Biol Med (1950) 1.00
Intravenous anesthetics; new concepts. I. Experimental aspects. Curr Res Anesth Analg (1952) 0.98