Published in J Clin Invest on September 01, 1957
Adrenocortical steroid metabolism and adrenal cortical function in liver disease. J Clin Invest (1960) 1.93
Comparative studies on adrenal cortical function and cortisol metabolism in healthy adults and in patients with shock due to infection. J Clin Invest (1958) 1.67
Conversion of cortisone to cortisol and prednisone to prednisolone. Br Med J (1967) 1.53
The influence of the thyroid on adrenal cortical function. J Clin Invest (1958) 1.37
Steroid metabolism in the cat. 2. Biliary and urinary excretion of metabolites of [4-C]corticosterone. Biochem J (1963) 1.21
Studies on pyrogenic steroids. I. Separation, identification, and measurement of unconjugated dehydroepiandrosterone, etiocholanolone, and adrosterone in human plasma. J Clin Invest (1961) 1.14
Metabolism of 11-oxygenated steroids. 2. 2-Methyl steroids. Biochem J (1959) 1.14
The metabolism of corticosterone in man. J Clin Invest (1960) 1.13
Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo. Diabetes (2012) 1.13
Metabolism of 11-oxygenated steroids. 3. Some 1-dehydro and 9 alpha-fluoro steroids. Biochem J (1964) 1.09
C-19-O-2 STEROIDS AND SOME OF THEIR PRECURSORS IN BLOOD FROM NORMAL HUMAN ADRENALS. J Clin Invest (1965) 1.06
Metabolism of 11-oxygenated steroids. 1. Influence of the A/B ring junction on the reduction of 11-oxo groups. Biochem J (1959) 0.96
Corticosteroid metabolism and rheumatoid arthritis. Ann Rheum Dis (1966) 0.91
Hirsutism, virilism, polycystic ovarian disease, and the steroid-gonadotropin-feedback system: a career retrospective. Am J Physiol Endocrinol Metab (2011) 0.89
Werner's syndrome (progeria of the adult); further pathological and biochemical observations. Br Med J (1959) 0.88
Steroid metabolism in the cat. Biliary and urinary excretion of metabolites of [4-14C]cortisone. Biochem J (1969) 0.87
CORTISOL METABOLISM IN MAN: OBSERVATIONS OF PATHWAYS, POOL SIZES OF METABOLITES AND RATES OF FORMATION OF METABOLITES. J Clin Invest (1959) 0.85
ON THE RATE OF FORMATION OF STERIDAL GLUCURONOSIDES IN PATIENTS WITH FAMILIAL AND ACQUIRED JAUNDICE. J Clin Invest (1964) 0.80
Differences in metabolism of Reichstein's substance S in normal adults and children. J Clin Invest (1958) 0.75
Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. Biochem J (1952) 14.48
The determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma. J Biol Chem (1954) 9.34
The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest (1955) 6.74
Windowless, Flow Type, Proportional Counter for Counting C14. Science (1950) 6.53
Hydrocortisone and cortisone injected into arthritic joints; comparative effects of and use of hydrocortisone as a local antiarthritic agent. J Am Med Assoc (1951) 6.28
The fate of hydrocortisone-4-C14 in man. J Clin Invest (1954) 4.21
17-Hydroxycorticosteroid metabolism in liver disease. J Clin Invest (1954) 3.13
Estimation of 17-hydroxycorticoids in urine. Metabolism (1952) 2.95
17-Hydroxycorticosteroids and 17-ketosteroids in urine on human subjects; clinical application of a method employing beta-glucuronidase hydrolysis. J Clin Endocrinol Metab (1953) 2.27
The characterization of four new metabolites of adrenocortical hormones. J Biol Chem (1955) 2.07
Some aspects of adrenal cortical metabolism. Clin Sci (Lond) (1954) 1.77
Effects in rheumatoid arthritis of hydrocortisone and cortisone injected intra-articularly. AMA Arch Intern Med (1952) 1.60
Metabolism of 4-C 14-cortisol in man: body distribution and rates of conjugation. J Clin Endocrinol Metab (1956) 1.57
Enzymatic mechanisms of hormone metabolism. I. Oxidation-reduction of the steroid nucleus. Recent Prog Horm Res (1956) 1.38
Investigations on the estimation of 17-hydroxycorticoids in urine using the Porter/Silber reaction. Acta Endocrinol (Copenh) (1953) 1.31
Tracer studies of the absorption and fate of steroid hormones in man. J Clin Invest (1956) 1.29
The effect of intra-articular injection of cortisone acetate and of hydrocortisone acetate in rheumatoid arthritis. Clin Sci (Lond) (1953) 1.24
The in vivo metabolism of cortisone. Endocrinology (1953) 1.24
The comparative effects of metacortandracin, 9-alpha-fluorohydrocortisone and hydrocortisone upon ACTH secretion in man. J Clin Endocrinol Metab (1955) 1.17
Effects of incubating compound E and related steroids with various surviving rat tissues. J Biol Chem (1952) 1.06
The conversion of cortisone acetate to other alphaketolic steroids. J Clin Endocrinol Metab (1953) 0.98
Metabolites of hydrocortisone and cortisone in synovial fluid in rheumatoid arthritis. J Clin Endocrinol Metab (1956) 0.94
Plasma levels of 17-hydroxycorticosteroids following the administration of adrenal steroids. Acta Endocrinol (Copenh) (1955) 0.93
Influence of adrenal cortical hormones upon the level of plasma amino acids in eviscerate rats. Endocrinology (1954) 0.92
Effects of 2-methylation on glucocorticoid activity of various C-21 steroids. Proc Soc Exp Biol Med (1957) 0.90
Corticosteroid metabolism in liver: studies on perfused rat livers. Endocrinology (1953) 0.86
Conversion of cortisone to compound F. J Clin Endocrinol Metab (1953) 0.86
Conversion of cortisone to 17-hydrocorticosterone by liver homogenates. Arch Biochem Biophys (1953) 0.81
Steroid compounds resulting from incubation of cortisone with surviving liver slices. Proc Soc Exp Biol Med (1953) 0.80
The relative potency of adrenal corticoids by the thymus involution method. Can J Biochem Physiol (1956) 0.79
Effect of adrenal cortical extract, cortisone and hydrocortisone upon the work of the adrenalectomized-eviscerate rat. Endocrinology (1953) 0.78
A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity. J Biol Chem (1952) 18.27
SJOEGREN'S SYNDROME. A CLINICAL, PATHOLOGICAL, AND SEROLOGICAL STUDY OF SIXTY-TWO CASES. Medicine (Baltimore) (1965) 7.46
The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest (1955) 6.74
Double isotope derivative assay of aldosterone in biological extracts. J Biol Chem (1960) 6.19
Ascorbic acid in aromatic hydroxylation. I. A model system for aromatic hydroxylation. J Biol Chem (1954) 5.08
Identification and assay of serotonin in brain. J Pharmacol Exp Ther (1956) 4.17
THE DEVELOPMENT OF MALIGNANT LYMPHOMA IN THE COURSE OF SJOEGREN'S SYNDROME. Am J Med (1964) 4.07
The gastric secretion of drugs: a pH partition hypothesis. J Pharmacol Exp Ther (1957) 3.99
Posterior subcapsular cataracts induced by corticosteroids in patients with rheumatoid arthritis. JAMA (1960) 3.94
Studies on metacortandralone and metacortandracin in rheumatoid arthritis; antirheumatic potency, metabolic effects, and hormonal properties. J Am Med Assoc (1955) 3.67
The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 3.60
A chemical method for the determination of free choline in plasma. J Biol Chem (1953) 3.57
Norepinephrine depletion as a possible mechanism of action of guanethidine (SU 5864), a new hypotensive agent. Proc Soc Exp Biol Med (1960) 3.26
On the mechanism of intestinal absorption of drugs. J Pharmacol Exp Ther (1959) 3.16
Some physico-chemical factors in drug action. J Pharm Pharmacol (1957) 3.13
The fate of antipyrine in man. J Pharmacol Exp Ther (1950) 3.05
Serotonin release as a possible mechanism of reserpine action. Science (1955) 3.03
The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. J Biol Chem (1953) 2.98
Arteritis of striated muscle in rheumatoid arthritis. Am J Pathol (1951) 2.86
Major undesirable side-effects resulting from prednisolone and prednisone. J Am Med Assoc (1955) 2.85
The effect of certain anions upon the accumulation and retention of iodide by the thyroid gland. Endocrinology (1952) 2.83
Ascorbic acid in aromatic hydroxylation. II. Products formed by reaction of substrates with ascorbic acid, ferrous ion, and oxygen. J Biol Chem (1954) 2.78
INTERACTION OF GUANETHIDINE WITH ADRENERGIC NEURONS. J Pharmacol Exp Ther (1965) 2.77
A concept for a role of serotonin and norepinephrine as chemical mediators in the brain. Ann N Y Acad Sci (1957) 2.71
Absorption of drugs from the rat small intestine. J Pharmacol Exp Ther (1958) 2.62
The fate of aminopyrine (pyramidon) in man and methods for the estimation of aminopyrine and its metabolites in biological material. J Pharmacol Exp Ther (1950) 2.54
The miscible pool and turnover rate of hydrocortisone in man. J Clin Invest (1956) 2.51
The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis. J Biol Chem (1959) 2.46
The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J Pharmacol Exp Ther (1957) 2.46
A broader spectrum of Sjogren's syndrome and its pathogenetic implications. Ann Rheum Dis (1961) 2.45
The fate of pentobarbital in man and dog and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 2.38
Enzymatic metabolism of drugs and other foreign compounds. Annu Rev Biochem (1958) 2.36
Bentonite flocculation test for rheumatoid arthritis. Proc Soc Exp Biol Med (1958) 2.35
Serotonin as a mediator of reserpine action in brain. J Pharmacol Exp Ther (1956) 2.26
Physiological disposition and metabolic fate of infused pentoses in man. J Clin Invest (1957) 2.25
A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671. J Pharmacol Exp Ther (1957) 2.20
Detoxication of drugs and other foreign compounds by liver microsomes. Science (1955) 2.20
Vascular lesions in rheumatoid arthritis. J Chronic Dis (1957) 2.15
Estimation of intracellular water in man. Am J Physiol (1950) 2.14
Evidence that serotonin has a role in brain function. Science (1955) 2.13
Vascularity of the early subcutaneous nodule of rheumatoid arthritis. AMA Arch Pathol (1953) 2.11
Pharmacological consequences of the selective release of peripheral norepinephrine by syrosingopine (Su 3118). J Pharmacol Exp Ther (1960) 2.10
The fate of thiopental in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1950) 2.10
Synthesis of hyaluronic acid by human synovial tissue slices. Science (1957) 2.09
Evidence that a humoral agent stimulates the adrenal cortex to secrete aldosterone in experimental secondary hyperaldosteronism. J Clin Invest (1959) 2.00
Interaction of reserpine, serotonin, and lysergic acid diethylamide in brain. Science (1955) 1.99
The clinical effects of cortisone and ACTH on rheumatic diseases. Bull N Y Acad Med (1951) 1.98
THE ENZYMOLOGY OF FEEDBACK INHIBITION OF GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE BY PURINE RIBONUCLEOTIDES. J Biol Chem (1964) 1.96
Adrenocortical steroid metabolism and adrenal cortical function in liver disease. J Clin Invest (1960) 1.93
Absorption of drugs from the stomach. I. The rat. J Pharmacol Exp Ther (1957) 1.86
Absorption of drugs from the stomach. II. The human. J Pharmacol Exp Ther (1957) 1.85
Humoral stimulation of adrenal cortical secretion. J Clin Invest (1962) 1.79
PSEUDOFEEDBACK INHIBITION OF PURINE SYNTHESIS BY 6-MERCAPTOPURINE RIBONUCLEOTIDE AND OTHER PURINE ANALOGUES. J Biol Chem (1964) 1.78
Mechanism of the potentiating action of beta-diethylaminoethyl diphenylpropylacetate. J Pharmacol Exp Ther (1954) 1.78
An improved method for assaying the steroidogenic potency of ACTH. Endocrinology (1955) 1.78
Enzymatic dealkylation of aminopyrine (pyramidon) and other alkylamines. J Biol Chem (1955) 1.77
The metabolic fate of phenylbutazone (butazolidin) in man. J Pharmacol Exp Ther (1955) 1.76
Effects of intra-articular hydrocortisone acetate on the clinical course, aminotripeptidase activity and other changes in the synovial fluid in rheumatoid arthritis. Ann Rheum Dis (1952) 1.76
Quantitative measurement of gastrointestinal blood loss. I. The use of radioactive Cr51 in patients with gastrointestinal hemorrhage. Am J Med (1958) 1.76
Cataracts in rheumatoid arthritis patients treated with corticosteroids. Description and differential diagnosis. Arch Ophthalmol (1961) 1.74
Effect of perchlorate on the human thyroid gland. Metabolism (1952) 1.74
Effect of ACTH on the erythrocyte-sedimentation rate and plasma-fibrinogen and serum-protein levels in normal persons. Lancet (1951) 1.72
An enzymatic spectrophotometric method for the determination of pyruvic acid in blood. J Lab Clin Med (1956) 1.72
ARA NOMENCLATURE AND CLASSIFICATION OF ARTHRITIS AND RHEUMATISM (TENTATIVE). Arthritis Rheum (1964) 1.69
Overproduction of uric acid as the cause of hyperuricemia in primary gout. J Clin Invest (1957) 1.66
Biochemical and pharmacological studies of RO 1-9569 (tetrabenazine), a nonindole tranquilizing agent with reserpine-like effects. J Pharmacol Exp Ther (1959) 1.63
On the mechanism of drug potentiation by iproniazid (2-isopropyl-1-isonicotinyl hydrazine). J Pharmacol Exp Ther (1956) 1.61
Potassium depletion and alkalosis; their association with hypertension and renal insufficiency. N Engl J Med (1954) 1.60
Effects in rheumatoid arthritis of hydrocortisone and cortisone injected intra-articularly. AMA Arch Intern Med (1952) 1.60
Physiological disposition and fate of chlorpromazine and a method for its estimation in biological material. J Pharmacol Exp Ther (1956) 1.59
Biogenesis and metabolism of 5-hydroxyindole compounds. J Biol Chem (1956) 1.58
Uricolysis in normal man. J Biol Chem (1953) 1.57
The enzymatic metabolism of hexobarbital (evipal). J Pharmacol Exp Ther (1955) 1.56
METHOTREXATE THERAPY IN PSORIATIC ARTHRITIS; DOUBLE-BLIND STUDY ON 21 PATIENTS. JAMA (1964) 1.56
Precursors of adrenal epinephrine and norepinephrine in vivo. Biochim Biophys Acta (1956) 1.56
Possible interrelationship between release of brain norepinephrine and serotonin by reserpine. Science (1957) 1.54
INFLUENCE OF GENETIC AND ENVIRONMENTAL FACTORS ON THE OCCURENCE OF RHEUMATOID ARTHRITIS AND RHEUMATOID FACTOR IN AMERICAN INDIANS. Bull Rheum Dis (1964) 1.54
Studies on dexamethasone, a new synthetic steroid, in rheurheumatoid arthritis: a preliminary report; adrenal cortical, metabolic and early clinical effects. Arthritis Rheum (1958) 1.52
Total body water in man. Am J Physiol (1950) 1.50
Inhibitory effects of beta-diethylaminoethyl diphenylpropylacetate on a variety of drug metabolic pathways in vitro. J Pharmacol Exp Ther (1954) 1.49
The importance of dissociaton constant and lipid-solubility in influencing the passage of drugs into the cerebrospinal fluid. J Pharmacol Exp Ther (1960) 1.47
Increased aldosterone secretion following acute constriction of the inferior vena cava. J Clin Invest (1958) 1.46
RECENT VIEWS ON MECHANISMS FOR LOWERING SYMPATHETIC TONE. Circulation (1963) 1.44
Glucose-6-phosphatase deficiency glycogen storage disease. Studies on the interrelationships of carbohydrate, lipid, and purine abnormalities. Pediatrics (1962) 1.44
On the mechanism of antidepressant action of imipraminelike drugs. Ann N Y Acad Sci (1962) 1.42
The use of procaine amide in cardiac arrhythmias. Circulation (1951) 1.42
Biochemical and pharmacological effects of the monoamine oxidase inhibitors, iproniazid, 1-phenyl-2-hydrazinopropane (JB 516) and 1-phenyl-3-hydrazinobutane (JB 835). J Pharmacol Exp Ther (1960) 1.41
Pathways of drug metabolism. J Pharm Pharmacol (1956) 1.41
The mechanism of serotonin and catecholamine uptake by platelets. J Pharmacol Exp Ther (1959) 1.40
Role of brain serotonin in reserpine action. Ann N Y Acad Sci (1957) 1.40
Structural requirements for bretylium and guanethidine-like activity. Life Sci (1962) 1.39
Metabolic effects of metacortandralone and metacortandracin. Ann N Y Acad Sci (1955) 1.39
Release of serotonin from blood platelets by reserpine in vitro. J Pharmacol Exp Ther (1957) 1.39
The enzymatic reduction of chloramphenicol, p-nitrobenzoic acid and other aromatic nitro compounds in mammals. J Pharmacol Exp Ther (1957) 1.38
Metabolism of drugs in subjects with Laennec's cirrhosis. Med Exp Int J Exp Med (1959) 1.38