Published in DNA Seq on January 01, 1992
A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition. Mol Cell Biol (2000) 4.27
The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. Nucleic Acids Res (1992) 3.57
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. Proc Natl Acad Sci U S A (1998) 3.18
Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. Mol Cell Biol (2002) 2.85
BET domain co-regulators in obesity, inflammation and cancer. Nat Rev Cancer (2012) 2.80
A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase. Mol Cell Biol (2002) 2.51
Latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts with RING3, a homolog of the Drosophila female sterile homeotic (fsh) gene. J Virol (1999) 2.36
Evidence that the SKI antiviral system of Saccharomyces cerevisiae acts by blocking expression of viral mRNA. Mol Cell Biol (1993) 2.26
RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F. Cell Growth Differ (2000) 2.13
Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2. Genetics (1998) 2.08
Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution. J Biol Chem (2009) 1.96
The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs. Nucleic Acids Res (1994) 1.68
Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines. J Proteome Res (2006) 1.64
Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse. Dev Dyn (2009) 1.51
E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia. Blood (2003) 1.51
Structure and function of latency-associated nuclear antigen. Curr Top Microbiol Immunol (2007) 1.39
Bromodomain analysis of Brd2-dependent transcriptional activation of cyclin A. Biochem J (2005) 1.38
Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails. BMC Struct Biol (2007) 1.32
Brd2 disruption in mice causes severe obesity without Type 2 diabetes. Biochem J (2009) 1.26
Tumor-specific and proliferation-specific gene expression typifies murine transgenic B cell lymphomagenesis. J Biol Chem (2006) 1.08
Activation-induced nuclear translocation of RING3. J Cell Sci (2000) 1.06
Bromodomain coactivators in cancer, obesity, type 2 diabetes, and inflammation. Discov Med (2010) 1.03
A bromodomain-containing protein from tomato specifically binds potato spindle tuber viroid RNA in vitro and in vivo. J Virol (2003) 0.96
The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis. J Leukoc Biol (2013) 0.92
The role of the double bromodomain-containing BET genes during mammalian spermatogenesis. Curr Top Dev Biol (2013) 0.92
Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation. Proc Natl Acad Sci U S A (1993) 0.91
Brd2 gene disruption causes "metabolically healthy" obesity: epigenetic and chromatin-based mechanisms that uncouple obesity from type 2 diabetes. Vitam Horm (2013) 0.90
Brd2 inhibits adipogenesis via the ERK1/2 signaling pathway in 3T3-L1 adipocytes. PLoS One (2013) 0.88
A systematic molecular genetic approach to study mammalian germline development. Int J Dev Biol (1998) 0.84
Zebrafish brd2a and brd2b are paralogous members of the bromodomain-ET (BET) family of transcriptional coregulators that show structural and expression divergence. BMC Dev Biol (2008) 0.84
BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell. PLoS One (2016) 0.83
The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins. Int J Mol Sci (2016) 0.77
Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis (1999) 45.01
A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Engl J Med (1996) 9.85
Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature (1991) 4.50
A novel cysteine-rich sequence motif. Cell (1991) 4.39
Microbial fouling of reverse-osmosis membranes used in advanced wastewater treatment technology: chemical, bacteriological, and ultrastructural analyses. Appl Environ Microbiol (1983) 3.74
Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation (2001) 3.57
The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. Nucleic Acids Res (1992) 3.57
Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei. J Cell Sci (2000) 3.50
The human PAX6 gene is mutated in two patients with aniridia. Nat Genet (1992) 3.37
Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis. Cell (1998) 3.36
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
Plasticity in the organization and sequences of human KIR/ILT gene families. Proc Natl Acad Sci U S A (2000) 3.09
Chitinase, beta-1,3-glucanase, osmotin, and extensin are expressed in tobacco explants during flower formation. Plant Cell (1990) 3.05
Genetic analysis of a class of polymyxin resistant partial revertants of stage O sporulation mutants of Bacillus subtilis: map of the chromosome region near the origin of replication. Mol Gen Genet (1979) 3.03
Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. Hum Mol Genet (2001) 2.95
An automated method for the measurement of folate activity. J Clin Pathol (1970) 2.94
DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans. Proc Natl Acad Sci U S A (2001) 2.86
A proteasome-related gene between the two ABC transporter loci in the class II region of the human MHC. Nature (1991) 2.84
DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing. J Mol Biol (1992) 2.82
Acupressure and the prevention of nausea and vomiting after laparoscopy. Br J Anaesth (1999) 2.77
Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol Cell Biol (1995) 2.61
Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells. Nature (1989) 2.61
Identification and preliminary characterization of a protein motif related to the zinc finger. Proc Natl Acad Sci U S A (1993) 2.55
cDNA clones coding for the heavy chain of human HLA-DR antigen. Proc Natl Acad Sci U S A (1982) 2.51
National study of microphthalmia, anophthalmia, and coloboma (MAC) in Scotland: investigation of genetic aetiology. J Med Genet (2002) 2.39
DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13. J Immunol (2000) 2.38
Human major histocompatibility complex contains genes for the major heat shock protein HSP70. Proc Natl Acad Sci U S A (1989) 2.34
Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles. Rheumatology (Oxford) (2006) 2.31
Second proteasome-related gene in the human MHC class II region. Nature (1991) 2.29
Dynamics of proteasome distribution in living cells. EMBO J (1997) 2.18
Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature (1982) 2.18
A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. Science (1997) 2.18
The MHC haplotype project: a resource for HLA-linked association studies. Tissue Antigens (2002) 2.16
Structure, sequence and polymorphism in the HLA-D region. Immunol Rev (1985) 2.16
The LILR family: modulators of innate and adaptive immune pathways in health and disease. Tissue Antigens (2004) 2.13
Molecular mapping of the human major histocompatibility complex by pulsed-field gel electrophoresis. Proc Natl Acad Sci U S A (1987) 2.13
Pitfalls in homozygosity mapping. Am J Hum Genet (2000) 2.12
Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature (1992) 2.12
Folate-binding protein is a marker for ovarian cancer. Cancer Res (1991) 2.12
Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science (1994) 2.08
Structural and functional homology between mammalian DNase IV and the 5'-nuclease domain of Escherichia coli DNA polymerase I. J Biol Chem (1994) 2.04
A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein. EMBO J (1999) 2.04
Isolation of cDNA clones encoding an enzyme from bovine cells that repairs oxidative DNA damage in vitro: homology with bacterial repair enzymes. Nucleic Acids Res (1991) 2.03
The human placental alkaline phosphatase gene and related sequences map to chromosome 2 band q37. Ann Hum Genet (1987) 2.00
Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors. Proc Natl Acad Sci U S A (1990) 1.93
Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin. J Biol Chem (2001) 1.93
Deranged DNA synthesis by bone marrow from vitamin B-12-deficient humans. Br J Haematol (1968) 1.93
The potential impact on travel times of closure and redistribution of A&E units in Ireland. Ir Med J (2004) 1.91
A new human HLA class II-related locus, DM. Nature (1991) 1.91
Six HLA-D region alpha-chain genes on human chromosome 6: polymorphisms and associations of DC alpha-related sequences with DR types. Proc Natl Acad Sci U S A (1984) 1.90
Homozygous human TAP peptide transporter mutation in HLA class I deficiency. Science (1994) 1.88
Sequences related to HLA-DR alpha chain on human chromosome 6: restriction enzyme polymorphism detected with DC alpha chain probes. Proc Natl Acad Sci U S A (1983) 1.85
Molecular characterization of a human DNA kinase. J Biol Chem (1999) 1.83
Do patient age and medical condition influence medical advice to stop smoking? Age Ageing (2000) 1.83
Using HIPE data as a research and planning tool: limitations and opportunities. Ir J Med Sci (2005) 1.82
Familial lipoatrophic diabetes with dominant transmission. A new syndrome. Q J Med (1974) 1.81
Splenomegaly in New Guinea. Bull World Health Organ (1967) 1.81
Complete nucleotide sequence of a functional HLA-DP beta gene and the region between the DP beta 1 and DP alpha 1 genes: comparison of the 5' ends of HLA class II genes. Nucleic Acids Res (1985) 1.76
The complete nucleotide sequence of the I-E alpha d immune response gene. Nucleic Acids Res (1983) 1.75
The flavohemoglobin of Escherichia coli confers resistance to a nitrosating agent, a "Nitric oxide Releaser," and paraquat and is essential for transcriptional responses to oxidative stress. J Biol Chem (1999) 1.72
Map of the human MHC. Immunol Today (1993) 1.72
Peer support for patients with type 2 diabetes: cluster randomised controlled trial. BMJ (2011) 1.69
Genetics and molecular genetics of the MHC. Rev Immunogenet (1999) 1.69
Characterization of recombination in the HLA class II region. Am J Hum Genet (1997) 1.69
The opsin family of proteins. Biochem J (1986) 1.67
Restoration of endogenous antigen processing in Burkitt's lymphoma cells by Epstein-Barr virus latent membrane protein-1: coordinate up-regulation of peptide transporters and HLA-class I antigen expression. Eur J Immunol (1995) 1.62
The human endoplasmic reticulum molecular chaperone BiP is an autoantigen for rheumatoid arthritis and prevents the induction of experimental arthritis. J Immunol (2001) 1.62
Killer-cell immunoglobulin-like receptor (KIR) nomenclature report, 2002. Tissue Antigens (2003) 1.60
Posttranslational processing of concanavalin A precursors in jackbean cotyledons. J Cell Biol (1986) 1.58
Placental expression of DC-SIGN may mediate intrauterine vertical transmission of HIV. J Pathol (2001) 1.58
Nomenclature for factors of the HLA system, 2004. Tissue Antigens (2005) 1.57
HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading. Curr Biol (1997) 1.57
Identification of phosphorylated sites in the mouse glucocorticoid receptor. J Biol Chem (1991) 1.54
Role of the ABC transporter Mdl1 in peptide export from mitochondria. Science (2001) 1.53
Effect of isotypes and allelic polymorphism on the binding of staphylococcal exotoxins to MHC class II molecules. J Immunol (1990) 1.53
Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi. Nature (1992) 1.50
Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma. Br J Cancer (1993) 1.49
The cluster of BTN genes in the extended major histocompatibility complex. Genomics (2001) 1.48
An epidemiologic study of breast cancer. Am J Epidemiol (1978) 1.47
Proteomics: new perspectives, new biomedical opportunities. Lancet (2000) 1.46
Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J Exp Med (1995) 1.46
Loss of heterozygosity and amplification on chromosome 11q in human ovarian cancer. Br J Cancer (1993) 1.44
Protein-sensitive and fasting hypoglycemia in children with the hyperinsulinism/hyperammonemia syndrome. J Pediatr (2001) 1.42
Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase. J Clin Endocrinol Metab (2001) 1.42
New cluster of ribosomal genes in Bacillus subtilis with regulatory role in sporulation. Nature (1978) 1.42
Linkage map of two HLA-SB beta and two HLA-SB alpha-related genes: an intron in one of the SB beta genes contains a processed pseudogene. Cell (1984) 1.41
Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures. J Immunol (2001) 1.41
An ovarian tumor marker with homology to vaccinia virus contains an IgV-like region and multiple transmembrane domains. Cancer Res (1992) 1.40
Analysis of the presynaptic signaling mechanisms underlying the inhibition of LTP in rat dentate gyrus by the tyrosine kinase inhibitor, genistein. Hippocampus (2002) 1.40