Published in J Pharmacol Exp Ther on May 01, 1961
Two types of muscarinic response to acetylcholine in mammalian cortical neurons. Proc Natl Acad Sci U S A (1985) 1.66
A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand. J Biol Chem (2008) 1.66
Acceleration of noradrenaline biosynthesis in the guinea-pig vas deferens by potassium. Br J Pharmacol (1970) 1.64
Muscarinic receptors in rat sympathetic ganglia. Br J Pharmacol (1980) 1.44
Effects of hexamethonium and hyoscine on the drug-induced depolarization of isolated superior cervical ganglia. Br J Pharmacol Chemother (1966) 1.28
The effect of reserpine on the pressor responses to angiotensin in the conscious cat. Br J Pharmacol (1970) 1.28
Cardiac sympathetic adrenergic pathways in which synaptic transmission is blocked by atropine sulfate. J Physiol (1967) 1.26
Pharmacological analysis of the muscarinic receptors involved when McN-A 343 stimulates acid secretion in the mouse isolated stomach. Br J Pharmacol (1985) 1.23
Selectivity of agonists for the active state of M1 to M4 muscarinic receptor subtypes. J Pharmacol Exp Ther (2008) 1.22
Allosteric modulation of muscarinic acetylcholine receptors. Curr Neuropharmacol (2007) 1.21
The actions of some cholinomimetic drugs on the isolated taenia of the guinea-pig caecum. Br J Pharmacol (1969) 1.19
The relative potencies of some agonists at M2 muscarinic receptors in guinea-pig ileum, atria and bronchi. Br J Pharmacol (1985) 1.18
The affinity of some acetylenic analogues of 4-DAMP methobromide for muscarinic receptors in guinea-pig ileum and atria. Br J Pharmacol (1988) 1.15
Effects of several muscarinic agonists on cardiac performance and the release of noradrenaline from sympathetic nerves of the perfused rabbit heart. Br J Pharmacol (1972) 1.14
RESPONSES OF THE RAT URINARY BLADDER IN SITU TO DRUGS AND TO NERVE STIMULATION. Br J Pharmacol Chemother (1965) 1.13
Effects of the muscarinic agonist McN-A-343 on responses to sympathetic nerve stimulation in the rabbit ear artery. Br J Pharmacol (1971) 1.10
Rational design of dualsteric GPCR ligands: quests and promise. Br J Pharmacol (2010) 1.07
Effects of McN-A-343 and DMPP on the uptake and release of 3 H-noradrenaline by guinea-pig atria. Br J Pharmacol (1972) 1.07
The effect of McN-A-343 on muscarinic receptors in the cerebral cortex and heart. Br J Pharmacol (1983) 1.06
Relative affinities of drugs acting at cholinoceptors in displacing agonist and antagonist radioligands: the NMS/Oxo-M ratio as an index of efficacy at cortical muscarinic receptors. Br J Pharmacol (1988) 1.05
Intramural nerves in the ventricular myocardium of the domestic fowl and other animals. Br J Pharmacol Chemother (1967) 1.04
Drugs for allosteric sites on receptors. Annu Rev Pharmacol Toxicol (2013) 1.04
Observations on the smooth muscle and contractile activity of the common bile duct. Ann Surg (1966) 1.03
The action of adrenergic neurone blocking agents and other drugs on the pressor responses of various agents in the anaesthetized rat. Br J Pharmacol Chemother (1967) 0.99
Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria. Br J Pharmacol (1991) 0.95
The relationship of the renal vascular activity of angiotensin II to the autonomic nervous system. J Clin Invest (1965) 0.92
Muscarinic activity of McN-A-343 and its value in muscarinic receptor classification. Br J Pharmacol (1987) 0.92
PARTICIPATION OF AN UNUSUAL GANGLIONIC PATHWAY IN THE MEDIATION OF THE PRESSOR EFFECT OF PHYSOSTIGMINE IN THE RAT. Br J Pharmacol Chemother (1964) 0.87
Evidence for muscarinic receptors in the adrenal medulla of the dog. Br J Pharmacol (1969) 0.87
Use of acetylcholine mustard to study allosteric interactions at the M(2) muscarinic receptor. J Pharmacol Exp Ther (2008) 0.84
Blocking effect of McN-A-343 on cardiac slowing produced by vagal stimulation. Br J Pharmacol (1971) 0.82
A new muscarinic agent: 1,4,5,6-tetrahydro-5-phenoxypyrimidine (AH 6405). Br J Pharmacol (1970) 0.82
Investigating the interaction of McN-A-343 with the M2 muscarinic receptor using its nitrogen mustard derivative. Biochem Pharmacol (2009) 0.80
Role of noradrenaline in the acute pressor response to angiotensin in conscious cats. Br J Pharmacol (1970) 0.80
Effects of the muscarinic agonist McN-A-343 on the release by sympathetic nerve stimulation of (3H)-noradrenaline from rabbit isolated ear arteries and guinea-pig atria. Br J Pharmacol (1974) 0.79
Investigating the interaction of McN-A-343 with the M muscarinic receptor using its nitrogen mustard derivative and ACh mustard. Br J Pharmacol (2010) 0.79
Pharmacological studies on the hypogastric ganglion of the rat and guinea-pig. Br J Pharmacol (1972) 0.79
Pharmacological characterization of muscarinic receptors involved in McN-A-343-induced effects on intestinal motility and heart rate in conscious dogs. Br J Pharmacol (1988) 0.78
Stereoselective inhibition of muscarinic receptor subtypes by the enantiomers of hexahydro-difenidol and acetylenic analogues. Br J Pharmacol (1990) 0.78
Responses to pressor substances in conscious and anaesthetized cats. Br J Pharmacol (1971) 0.77
Effects of asparagine mutagenesis of conserved aspartic acids in helix 2 (D2.50) and 3 (D3.32) of M1-M4 muscarinic receptors on the irreversible binding of nitrogen mustard analogs of acetylcholine and McN-A-343. Biochemistry (2013) 0.76
Modulation by the muscarinic agonist McN-A-343 of release of noradrenaline from sympathetic neurones in the rabbit pulmonary artery [proceedings]. Br J Pharmacol (1980) 0.75
Antagonistic properties of McNeil-A-343 at 5-HT4 and 5-HT3 receptors. Br J Pharmacol (1994) 0.75
Drug receptor sites in the rabbit saphenous nerve. Br J Pharmacol (1970) 0.75
An analysis of the peripheral effects of l-DOPA on autonomic nerve function. Br J Pharmacol (1974) 0.75
Proceedings of the British Pharmacological Society 8th-10th September, 1982. Abstracts. Br J Pharmacol (1982) 0.75
Effect of tilting on the pressor responses to McN-A-343, a muscarinic sympathetic ganglion stimulant. Br J Pharmacol (1980) 0.75
Effects of McN-A-343 on responses induced by sympathetic nerve stimulation in the rabbit isolated ear artery. Br J Pharmacol (1970) 0.75
How the birefringence of vertebrate rods is affected by light. J Physiol (1970) 0.75
Action of some ganglion-stimulating substances on the secretion of saliva from the submandibular gland. Br J Pharmacol Chemother (1962) 0.75
SELECTIVE RAT TOXICANT. Science (1964) 3.42
Enhancement of inhibitory and excitatory effects of catecholamines. J Pharmacol Exp Ther (1960) 1.09
A pharmacological comparison of therapeutically useful centrally acting skeletal muscle relaxants. J Pharmacol Exp Ther (1960) 0.88
2-AMINO-5-ARYL-2-OXAZOLINES. POTENT NEW ANORECTIC AGENTS. J Med Chem (1963) 0.87
A rapid method for assessing drug inhibition of feeding behavior. J Pharmacol Exp Ther (1963) 0.79