PubRank

F R Maxfield

Author PubWeight™ 227.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Endocytosis. Physiol Rev 1997 7.33
2 Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin. Cell 1982 7.23
3 Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell 1984 6.50
4 Membrane transport in the endocytic pathway. Curr Opin Cell Biol 1995 5.86
5 Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. J Biol Chem 1980 5.24
6 Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts. J Cell Biol 1982 5.11
7 Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J Cell Biol 1993 5.08
8 Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol 1984 4.88
9 Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 1994 4.36
10 Collection of insulin, EGF and alpha2-macroglobulin in the same patches on the surface of cultured fibroblasts and common internalization. Cell 1978 3.90
11 Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome. J Cell Biol 1989 3.84
12 Functional expression of the human transferrin receptor cDNA in Chinese hamster ovary cells deficient in endogenous transferrin receptor. J Cell Biol 1987 3.28
13 Ca(2+)- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils. Nature 1995 3.22
14 Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells. Nat Cell Biol 2001 3.22
15 Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron 1996 3.14
16 Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J Cell Biol 1995 3.03
17 Quantification of low density lipoprotein and transferrin endocytic sorting HEp2 cells using confocal microscopy. J Cell Sci 1994 2.88
18 Transglutaminase is essential in receptor-mediated endocytosis of alpha 2-macroglobulin and polypeptide hormones. Nature 1980 2.82
19 Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol Biol Cell 1995 2.74
20 Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J 1998 2.63
21 Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails. J Cell Biol 1999 2.55
22 alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. J Cell Biol 1979 2.48
23 An endocytosed TGN38 chimeric protein is delivered to the TGN after trafficking through the endocytic recycling compartment in CHO cells. J Cell Biol 1998 2.43
24 Cholesterol depletion induces large scale domain segregation in living cell membranes. Proc Natl Acad Sci U S A 2001 2.41
25 Amines inhibit the clustering of alpha2-macroglobulin and EGF on the fibroblast cell surface. Nature 1979 2.41
26 Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog. Biophys J 1998 2.30
27 Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes. J Cell Biol 1992 2.24
28 Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells. J Cell Biol 1995 2.19
29 Ca2+-dependent myosin II activation is required for uropod retraction during neutrophil migration. J Cell Sci 2000 2.19
30 Status of empirical methods for the prediction of protein backbone topography. Biochemistry 1976 2.12
31 Oriented endocytic recycling of alpha5beta1 in motile neutrophils. Blood 2000 2.11
32 Human transferrin receptor internalization is partially dependent upon an aromatic amino acid on the cytoplasmic domain. Cell Regul 1990 2.09
33 The effect of neighboring charges on the helix forming ability of charged amino acids in proteins. Macromolecules 1976 2.08
34 Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways. J Cell Biol 1999 2.06
35 Characterization of rapid membrane internalization and recycling. J Biol Chem 2000 2.03
36 Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment. J Cell Biol 1995 2.02
37 Role of membrane organization and membrane domains in endocytic lipid trafficking. Traffic 2000 2.02
38 Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells. J Cell Biol 1989 1.98
39 Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line. J Cell Biol 1983 1.96
40 Acidification of endocytic vesicles by an ATP-dependent proton pump. J Cell Biol 1983 1.84
41 Acidification of morphologically distinct endosomes in mutant and wild-type Chinese hamster ovary cells. J Cell Biol 1987 1.82
42 Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infect Immun 1998 1.75
43 Sphingomyelinase treatment induces ATP-independent endocytosis. J Cell Biol 1998 1.72
44 Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix. J Leukoc Biol 1997 1.69
45 Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils. J Cell Biol 1990 1.69
46 Local cytoplasmic calcium gradients in living mitotic cells. Nature 1985 1.69
47 Intracellular fusion of sequentially formed endocytic compartments. J Cell Biol 1988 1.67
48 Isolation of a temperature-sensitive variant Chinese hamster ovary cell line with a morphologically altered endocytic recycling compartment. J Cell Physiol 1993 1.63
49 Bafilomycin A1 treatment retards transferrin receptor recycling more than bulk membrane recycling. J Biol Chem 1997 1.61
50 Receptor-mediated endocytosis of diphtheria toxin by cells in culture. Proc Natl Acad Sci U S A 1982 1.59
51 The End2 mutation in CHO cells slows the exit of transferrin receptors from the recycling compartment but bulk membrane recycling is unaffected. J Cell Biol 1993 1.54
52 Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science 1992 1.53
53 Preparation of solutions with free calcium concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid. Anal Biochem 1991 1.51
54 Acidification of endocytic compartments and the intracellular pathways of ligands and receptors. J Cell Biochem 1984 1.49
55 Cytoskeleton-dependent membrane domain segregation during neutrophil polarization. Mol Biol Cell 2001 1.47
56 Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium. Proc Natl Acad Sci U S A 1986 1.45
57 Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. J Biol Chem 1997 1.45
58 Distribution and transport of cholesterol in Caenorhabditis elegans. Mol Biol Cell 2001 1.42
59 Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. J Biol Chem 1999 1.42
60 Kinetics of endosome acidification in mutant and wild-type Chinese hamster ovary cells. J Cell Biol 1987 1.42
61 Transition from metaphase to anaphase is accompanied by local changes in cytoplasmic free calcium in Pt K2 kidney epithelial cells. Proc Natl Acad Sci U S A 1986 1.40
62 Thyrotropin-releasing hormone-induced changes in intracellular [Ca2+] measured by microspectrofluorometry on individual quin2-loaded cells. J Cell Biol 1984 1.39
63 Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule. Blood 2000 1.38
64 Microinjection of Ca++-calmodulin causes a localized depolymerization of microtubules. J Cell Biol 1983 1.37
65 Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits. Proc Natl Acad Sci U S A 1979 1.36
66 Cytosolic free calcium increases before and oscillates during frustrated phagocytosis in macrophages. J Cell Biol 1987 1.35
67 Attachment to fibronectin or vitronectin makes human neutrophil migration sensitive to alterations in cytosolic free calcium concentration. J Cell Biol 1991 1.26
68 Receptor-mediated uptake of 3,3',5-triiodo-L-thyronine by cultured fibroblasts. Proc Natl Acad Sci U S A 1980 1.25
69 Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages. J Cell Biol 1990 1.22
70 Applications of ratio fluorescence microscopy in the study of cell physiology. FASEB J 1994 1.20
71 Long-lasting and rapid calcium changes during mitosis. J Cell Biol 1988 1.19
72 Kinetics of alpha 2-macroglobulin endocytosis and degradation in mutant and wild-type Chinese hamster ovary cells. J Cell Physiol 1989 1.19
73 Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine. J Exp Med 1995 1.19
74 Intracellular free calcium levels are reduced in mitotic Pt K2 epithelial cells. Proc Natl Acad Sci U S A 1985 1.18
75 Conformational changes in the receptors for epidermal growth factor and asialoglycoproteins induced by the mildly acidic pH found in endocytic vesicles. J Biol Chem 1984 1.18
76 Local and global changes in cytosolic free calcium in neutrophils during chemotaxis and phagocytosis. Cell Calcium 1990 1.16
77 Ratio imaging instrumentation. Methods Cell Biol 1998 1.12
78 Clearance of chylomicron remnants by the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. J Biol Chem 1991 1.11
79 Intracellular calcium levels correlate with speed and persistent forward motion in migrating neutrophils. Biophys J 1995 1.11
80 Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation. J Cell Biol 1988 1.10
81 Quantitative fluorescence techniques for the characterization of endocytosis in intact cells. Subcell Biochem 1993 1.10
82 Measurement of vacuolar pH and cytoplasmic calcium in living cells using fluorescence microscopy. Methods Enzymol 1989 1.09
83 Helix-coil stability constants for the naturally occurring amino acids in water. IX. Glutamic acid parameters from random poly(hydroxybutylglutamine-co-L-glutamic acid). Macromolecules 1976 1.09
84 Improvements in the prediction of protein backbone topography by reduction of statistical errors. Biochemistry 1979 1.09
85 Transferrin receptor containing the SDYQRL motif of TGN38 causes a reorganization of the recycling compartment but is not targeted to the TGN. J Cell Biol 1996 1.08
86 Beta-very low density lipoprotein is sequestered in surface-connected tubules in mouse peritoneal macrophages. J Cell Biol 1993 1.06
87 Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia. J Biol Chem 2000 1.05
88 Binding, surface mobility, internalization, and degradation of rhodamine-labeled alpha 2-macroglobulin. Biochemistry 1981 1.05
89 Receptor-mediated endocytosis of alpha 2-macroglobulin in cultured fibroblasts. J Histochem Cytochem 1980 1.04
90 Tumor necrosis factor increases the number of epidermal growth factor receptors on human fibroblasts. J Biol Chem 1987 1.04
91 The uptake and degradation of matrix-bound lipoproteins by macrophages require an intact actin Cytoskeleton, Rho family GTPases, and myosin ATPase activity. J Biol Chem 2001 1.03
92 The distal pathway of lipoprotein-induced cholesterol esterification, but not sphingomyelinase-induced cholesterol esterification, is energy-dependent. J Biol Chem 1996 1.01
93 Phagocytosis of wild-type Legionella pneumophila occurs through a wortmannin-insensitive pathway. Infect Immun 2001 1.01
94 Clathrin hub expression affects early endosome distribution with minimal impact on receptor sorting and recycling. Mol Biol Cell 2001 0.99
95 Unique cellular events occurring during the initial interaction of macrophages with matrix-retained or methylated aggregated low density lipoprotein (LDL). Prolonged cell-surface contact during which ldl-cholesteryl ester hydrolysis exceeds ldl protein degradation. J Biol Chem 1999 0.98
96 Flotillas of lipid rafts fore and aft. Proc Natl Acad Sci U S A 2001 0.96
97 The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages. J Cell Biol 1991 0.94
98 Loss of alpha 2-macroglobulin and epidermal growth factor surface binding induced by phenothiazines and naphthalene sulfonamides. J Cell Physiol 1984 0.94
99 Immunolocalization of acyl-coenzyme A:cholesterol O-acyltransferase in macrophages. J Biol Chem 1998 0.93
100 Enrichment of acyl coenzyme A:cholesterol O-acyltransferase near trans-golgi network and endocytic recycling compartment. Arterioscler Thromb Vasc Biol 2000 0.92
101 Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake. J Biol Chem 1995 0.92
102 Cholesterol: stuck in traffic. Nat Cell Biol 1999 0.92
103 Regulation of neutrophil motility and adhesion by intracellular calcium transients. Blood Cells 1993 0.92
104 Intracellular calcium and calcineurin regulate neutrophil motility on vitronectin through a receptor identified by antibodies to integrins alphav and beta3. Blood 1996 0.91
105 Regulation of endocytic processes by pH. Trends Pharmacol Sci 1988 0.90
106 Simultaneous addition of EGF prolongs the increase in cytosolic free calcium seen in response to bradykinin in NRK-49F cells. J Cell Physiol 1988 0.89
107 Uptake of fibrillar beta-amyloid by microglia isolated from MSR-A (type I and type II) knockout mice. Neuroreport 2001 0.88
108 Calcium and signal transduction in granulocytes. Curr Opin Hematol 1996 0.88
109 Binding and mobility of the cell surface receptors for 3,3',5-triiodo-L-thyronine. Science 1981 0.88
110 Polarized binding of lipoprotein lipase to endothelial cells. Implications for its physiological actions. Arterioscler Thromb 1992 0.87
111 Acidification-dependent dissociation of endocytosed insulin precedes that of endocytosed proteins bearing the mannose 6-phosphate recognition marker. J Biol Chem 1990 0.86
112 Conformational study of [Leu5]-enkephalin by laser Raman spectroscopy. Int J Pept Protein Res 1980 0.86
113 Resting [Ca2+]i and [Ca2+]i transients are similar in fibroblasts from normal and Alzheimer's donors. Neurobiol Aging 1992 0.85
114 Changes in yolk platelet pH during Xenopus laevis development correlate with yolk utilization. A quantitative confocal microscopy study. J Cell Sci 1994 0.85
115 Vesicular and nonvesicular transport of phosphatidylcholine in polarized HepG2 cells. Traffic 2001 0.85
116 Acidification of endocytic vesicles and the intracellular pathways of ligands and receptors. Ann N Y Acad Sci 1983 0.84
117 Yolk platelets in Xenopus oocytes maintain an acidic internal pH which may be essential for sodium accumulation. J Cell Biol 1994 0.84
118 Effects of buffering intracellular free calcium on neutrophil migration through three-dimensional matrices. J Cell Physiol 1997 0.84
119 The actin cytoskeleton is important for the stimulation of cholesterol esterification by atherogenic lipoproteins in macrophages. J Biol Chem 1994 0.83
120 Calcium and calmodulin in the regulation of the microtubular cytoskeleton. Ann N Y Acad Sci 1986 0.82
121 Properties of acidified compartments in hippocampal neurons. Eur J Cell Biol 1993 0.82
122 Nerve growth factor potentiates bradykinin-induced calcium influx and release in PC12 cells. J Neurochem 1991 0.81
123 A Raman spectroscopic investigation of the disulfide conformation in oxytocin and lysine vasopressin. Biochemistry 1977 0.79
124 Fc and C3bi receptors and the differentiation antigen BH2-Ag are randomly distributed in the plasma membrane of locomoting neutrophils. J Cell Biol 1990 0.79
125 Study of the state of ionization of [Leu5]-enkephalin in the crystal and in solution. Int J Pept Protein Res 1980 0.78
126 Evidence for prolonged cell-surface contact of acetyl-LDL before entry into macrophages. Arterioscler Thromb Vasc Biol 1997 0.77
127 Cyclized dipeptide model for a beta-bend. Proc Natl Acad Sci U S A 1979 0.75
128 Effect and cellular site of action of cysteine protease inhibitors on the cholesterol esterification pathway in macrophages and Chinese hamster ovary cells. Biochemistry 1995 0.75
129 Spectroscopic study of the conformations of proline-containing oligopeptides in the crystalline state and in solution. Int J Pept Protein Res 1981 0.75
130 Endocytosis. Adv Nephrol Necker Hosp 2000 0.75